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Fukushima Medical University: Fukushima, JP

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Motonobu Saito

Works (50 of 64)

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Lenvatinib suppress FGF19–FGFR4 signaling to enhance antitumor immune response in gastric cancer

Gastric Cancer
2025-02-13 | Journal article
Contributors: Yuya Maruyama; Motonobu Saito; Shotaro Nakajima; Katsuharu Saito; Hiroya Suzuki; Ryo Kanoda; Hirokazu Okayama; Hiroyuki Hanayama; Wataru Sakamoto; Zenichiro Saze et al.
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Crossref

TIM-3 Expression on Dendritic Cells in Colorectal Cancer

Cancers
2024-05 | Journal article | Author
Contributors: Mei Sakuma; Masanori Katagata; Hirokazu Okayama; Shotaro Nakajima; Katsuharu Saito; Takahiro Sato; Satoshi Fukai; Hideaki Tsumuraya; Hisashi Onozawa; Wataru Sakamoto et al.
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Multidisciplinary Digital Publishing Institute

TGFβ-Responsive Stromal Activation Occurs Early in Serrated Colorectal Carcinogenesis

International Journal of Molecular Sciences
2024-04-24 | Journal article
Contributors: Hideaki Tsumuraya; Hirokazu Okayama; Masanori Katagata; Akira Matsuishi; Satoshi Fukai; Misato Ito; Wataru Sakamoto; Motonobu Saito; Tomoyuki Momma; Shotaro Nakajima et al.
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Crossref
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TIM-3 Expression and M2 Polarization of Macrophages in the TGFβ-Activated Tumor Microenvironment in Colorectal Cancer

Cancers
2023-10-11 | Journal article
Contributors: Masanori Katagata; Hirokazu Okayama; Shotaro Nakajima; Katsuharu Saito; Takahiro Sato; Mei Sakuma; Satoshi Fukai; Eisei Endo; Wataru Sakamoto; Motonobu Saito et al.
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Crossref
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A Potential Biomarker of Dynamic Change in Peripheral CD45RA<sup>−</sup>CD27<sup>+</sup>CD127<sup>+</sup> Central Memory T Cells for Anti-PD-1 Therapy in Patients with Esophageal Squamous Cell Carcinoma

Cancers
2023-07 | Journal article | Author
Contributors: Mei Sakuma; Kosaku Mimura; Shotaro Nakajima; Akinao Kaneta; Tomohiro Kikuchi; Azuma Nirei; Takeshi Tada; Hiroyuki Hanayama; Hirokazu Okayama; Wataru Sakamoto et al.
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Multidisciplinary Digital Publishing Institute

ARID1A deficiency is targetable by AKT inhibitors in HER2-negative gastric cancer

Gastric Cancer
2023-05 | Journal article
Contributors: Takahiro Sato; Motonobu Saito; Shotaro Nakajima; Katsuharu Saito; Masanori Katagata; Satoshi Fukai; Hirokazu Okayama; Wataru Sakamoto; Zenichiro Saze; Tomoyuki Momma et al.
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Crossref

The Impact of Tumor Cell-Intrinsic Expression of Cyclic GMP-AMP Synthase (cGAS)-Stimulator of Interferon Genes (STING) on the Infiltration of CD8<sup>+</sup> T Cells and Clinical Outcomes in Mismatch Repair Proficient/Microsatellite Stable Colorectal Cancer

Cancers
2023-05 | Journal article | Author
Contributors: Shotaro Nakajima; Akinao Kaneta; Hirokazu Okayama; Katsuharu Saito; Tomohiro Kikuchi; Eisei Endo; Takuro Matsumoto; Satoshi Fukai; Mei Sakuma; Takahiro Sato et al.
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Multidisciplinary Digital Publishing Institute

Landscape of EBV-positive gastric cancer

Gastric Cancer
2021-09 | Journal article
Contributors: Motonobu Saito; Koji Kono
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Crossref

ARID1A deficiency in EBV-positive gastric cancer is partially regulated by EBV-encoded miRNAs, but not by DNA promotor hypermethylation

Carcinogenesis
2021-02-11 | Journal article
Contributors: Koji Kase; Motonobu Saito; Shotaro Nakajima; Daisuke Takayanagi; Katsuharu Saito; Leo Yamada; Mai Ashizawa; Hiroshi Nakano; Hiroyuki Hanayama; Hisashi Onozawa et al.
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Crossref

Selective sensitivity of EZH2 inhibitors based on synthetic lethality in ARID1A-deficient gastric cancer

Gastric Cancer
2021-01-06 | Journal article
Contributors: Leo Yamada; Motonobu Saito; Aung Kyi Thar Min; Katsuharu Saito; Mai Ashizawa; Koji Kase; Shotaro Nakajima; Hisashi Onozawa; Hirokazu Okayama; Hisahito Endo et al.
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Crossref

Tn Antigen Expression Defines an Immune Cold Subset of Mismatch-Repair Deficient Colorectal Cancer

International Journal of Molecular Sciences
2020-11 | Journal article | Author
Contributors: Takuro Matsumoto; Hirokazu Okayama; Shotaro Nakajima; Katsuharu Saito; Hiroshi Nakano; Eisei Endo; Koji Kase; Misato Ito; Naoto Yamauchi; Leo Yamada et al.
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Multidisciplinary Digital Publishing Institute

Heterogeneity of ARID1A expression in gastric cancer may affect patient survival and therapeutic efficacy

Human Pathology
2020-07 | Journal article
Contributors: Motonobu Saito; Takashi Kohno; Koji Kono
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Crossref

miRNA-148a-3p Regulates Immunosuppression in DNA Mismatch Repair–Deficient Colorectal Cancer by Targeting PD-L1

Molecular Cancer Research
2019-06-01 | Journal article
Contributors: Mai Ashizawa; Hirokazu Okayama; Teruhide Ishigame; Aung Kyi Thar Min; Katsuharu Saito; Daisuke Ujiie; Yuko Murakami; Tomohiro Kikuchi; Yuko Nakayama; Masaru Noda et al.
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Crossref

Prognostic role of ARID1A negative expression in gastric cancer

Scientific Reports
2019-05-01 | Journal article
Contributors: Mai Ashizawa; Motonobu Saito; Aung Kyi Thar Min; Daisuke Ujiie; Katsuharu Saito; Takahiro Sato; Tomohiro Kikuchi; Hirokazu Okayama; Shotaro Fujita; Hisahito Endo et al.
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Crossref

A Nucleolar Stress-Specific p53-miR-101 Molecular Circuit Functions as an Intrinsic Tumor-Suppressor Network.

EBioMedicine
2018-07 | Journal article
Contributors: Fujiwara Y; Saito M; Robles AI; Nishida M; Takeshita F; Watanabe M; Ochiya T; Yokota J; Kohno T; Harris CC et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Development of targeted therapy and immunotherapy for treatment of small cell lung cancer.

Japanese journal of clinical oncology
2018-07 | Journal article
Contributors: Saito M; Shiraishi K; Goto A; Suzuki H; Kohno T; Kono K
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Prognostic impact of preoperative lymphocyte-to-monocyte ratio in patients with colorectal cancer with special reference to myeloid-derived suppressor cells.

Fukushima journal of medical science
2018-07 | Journal article
Contributors: Shimura T; Shibata M; Gonda K; Hayase S; Sakamoto W; Okayama H; Fujita S; Saito M; Momma T; Ohki S et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Prognostic role of FUT8 expression in relation to p53 status in stage II and III colorectal cancer.

PloS one
2018-07 | Journal article
Contributors: Noda M; Okayama H; Kofunato Y; Chida S; Saito K; Tada T; Ashizawa M; Nakajima T; Aoto K; Kikuchi T et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

The intratumoral distribution influences the prognostic impact of CD68- and CD204-positive macrophages in non-small cell lung cancer.

Lung cancer (Amsterdam, Netherlands)
2018-07 | Journal article
Contributors: Li Z; Maeda D; Yoshida M; Umakoshi M; Nanjo H; Shiraishi K; Saito M; Kohno T; Konno H; Saito H et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Epithelial-mesenchymal transition-converted tumor cells can induce T-cell apoptosis through upregulation of programmed death ligand 1 expression in esophageal squamous cell carcinoma.

Cancer medicine
2018-05 | Journal article
Contributors: Thar Min AK; Okayama H; Saito M; Ashizawa M; Aoto K; Nakajima T; Saito K; Hayase S; Sakamoto W; Tada T et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Targeted therapy according to next generation sequencing-based panel sequencing.

Fukushima journal of medical science
2018-04 | Journal article
Contributors: Saito M; Momma T; Kono K
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Serum transthyretin level is associated with prognosis of patients with gastric cancer.

The Journal of surgical research
2018-03 | Journal article
Contributors: Shimura T; Shibata M; Gonda K; Okayama H; Saito M; Momma T; Ohki S; Kono K
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Augmentation of antibody-dependent cellular cytotoxicity with defucosylated monoclonal antibodies in patients with GI-tract cancer.

Oncology letters
2017-12 | Journal article
Contributors: Nakajima T; Okayama H; Ashizawa M; Noda M; Aoto K; Saito M; Monma T; Ohki S; Shibata M; Takenoshita S et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Decreased expression of CADM1 and CADM4 are associated with advanced stage breast cancer.

Oncology letters
2017-12 | Journal article
Contributors: Saito M; Goto A; Abe N; Saito K; Maeda D; Ohtake T; Murakami Y; Takenoshita S
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Enhanced expression of KIF4A in colorectal cancer is associated with lymph node metastasis.

Oncology letters
2017-12 | Journal article
Contributors: Matsumoto Y; Saito M; Saito K; Kanke Y; Watanabe Y; Onozawa H; Hayase S; Sakamoto W; Ishigame T; Momma T et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Gene aberration profile of tumors of adolescent and young adult females.

Oncotarget
2017-12 | Journal article
Contributors: Kanke Y; Shimomura A; Saito M; Honda T; Shiraishi K; Shimada Y; Watanabe R; Yoshida H; Yoshida M; Shimizu C et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Identification of candidate responders for anti-PD-L1/PD-1 immunotherapy, Rova-T therapy, or EZH2 inhibitory therapy in small-cell lung cancer.

Molecular and clinical oncology
2017-12 | Journal article
Contributors: Saito M; Saito K; Shiraishi K; Maeda D; Suzuki H; Minamiya Y; Kono K; Kohno T; Goto A
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

TBX19 is overexpressed in colorectal cancer and associated with lymph node metastasis.

Fukushima journal of medical science
2017-12 | Journal article
Contributors: Ando J; Saito M; Imai JI; Ito E; Yanagisawa Y; Honma R; Saito K; Tachibana K; Momma T; Ohki S et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Upregulated HOXA9 expression is associated with lymph node metastasis in colorectal cancer.

Oncology letters
2017-12 | Journal article
Contributors: Watanabe Y; Saito M; Saito K; Matsumoto Y; Kanke Y; Onozawa H; Hayase S; Sakamoto W; Ishigame T; Momma T et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Upregulated solute carrier family 37 member 1 in colorectal cancer is associated with poor patient outcome and metastasis.

Oncology letters
2017-12 | Journal article
Contributors: Kikuchi D; Saito M; Saito K; Watanabe Y; Matsumoto Y; Kanke Y; Onozawa H; Hayase S; Sakamoto W; Ishigame T et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Immunogenic tumor cell death induced by chemotherapy in patients with breast cancer and esophageal squamous cell carcinoma.

Oncology reports
2017-11 | Journal article
Contributors: Aoto K; Mimura K; Okayama H; Saito M; Chida S; Noda M; Nakajima T; Saito K; Abe N; Ohki S et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

The genomic and epigenomic landscape in thymic carcinoma.

Carcinogenesis
2017-10 | Journal article
Contributors: Saito M; Fujiwara Y; Asao T; Honda T; Shimada Y; Kanai Y; Tsuta K; Kono K; Watanabe S; Ohe Y et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

CDX2 is involved in microRNA-associated inflammatory carcinogenesis in gastric cancer.

Oncology letters
2017-09 | Journal article
Contributors: Saito M; Okayama H; Saito K; Ando J; Kumamoto K; Nakamura I; Ohki S; Ishi Y; Takenoshita S
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

ING2, a tumor associated gene, enhances PAI‑1 and HSPA1A expression with HDAC1 and mSin3A through the PHD domain and C‑terminal.

Molecular medicine reports
2017-09 | Journal article
Contributors: Ohkouchi C; Kumamoto K; Saito M; Ishigame T; Suzuki SI; Takenoshita S; Harris CC
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

The low expression of miR-451 predicts a worse prognosis in non-small cell lung cancer cases.

PloS one
2017-07 | Journal article
Contributors: Goto A; Tanaka M; Yoshida M; Umakoshi M; Nanjo H; Shiraishi K; Saito M; Kohno T; Kuriyama S; Konno H et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Clinicopathological examination of dipeptidase 1 expression in colorectal cancer.

Biomedical reports
2017-03 | Journal article
Contributors: Tachibana K; Saito M; Imai JI; Ito E; Yanagisawa Y; Honma R; Saito K; Ando J; Momma T; Ohki S et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Treatment of lung adenocarcinoma by molecular-targeted therapy and immunotherapy.

Surgery today
2017-03 | Journal article
Contributors: Saito M; Suzuki H; Kono K; Takenoshita S; Kohno T
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Utility of Assessing the Number of Mutated KRAS, CDKN2A, TP53, and SMAD4 Genes Using a Targeted Deep Sequencing Assay as a Prognostic Biomarker for Pancreatic Cancer.

Pancreas
2017-03 | Journal article
Contributors: Hayashi H; Kohno T; Ueno H; Hiraoka N; Kondo S; Saito M; Shimada Y; Ichikawa H; Kato M; Shibata T et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Annexin A1 is involved in resistance to 5-FU in colon cancer cells.

Oncology reports
2016-11 | Journal article
Contributors: Onozawa H; Saito M; Saito K; Kanke Y; Watanabe Y; Hayase S; Sakamoto W; Ishigame T; Momma T; Ohki S et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Genomic Amplification of CD274 (PD-L1) in Small-Cell Lung Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research
2016-09 | Journal article
Contributors: George J; Saito M; Tsuta K; Iwakawa R; Shiraishi K; Scheel AH; Uchida S; Watanabe SI; Nishikawa R; Noguchi M et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma.

Nature communications
2016-08 | Journal article
Contributors: Shiraishi K; Okada Y; Takahashi A; Kamatani Y; Momozawa Y; Ashikawa K; Kunitoh H; Matsumoto S; Takano A; Shimizu K et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Gene aberrations for precision medicine against lung adenocarcinoma.

Cancer science
2016-05 | Journal article
Contributors: Saito M; Shiraishi K; Kunitoh H; Takenoshita S; Yokota J; Kohno T
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Multiplex Diagnosis of Oncogenic Fusion and MET Exon Skipping by Molecular Counting Using Formalin-Fixed Paraffin Embedded Lung Adenocarcinoma Tissues.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
2015-12 | Journal article
Contributors: Sunami K; Furuta K; Tsuta K; Sasada S; Izumo T; Nakaoku T; Shimada Y; Saito M; Nokihara H; Watanabe S et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Comparisons between mouse and human studies will help the prevention, diagnosis, and treatment of the deadliest type of lung cancer.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
2015-04 | Journal article
Contributors: Kohno T; Saito M
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Development of lung adenocarcinomas with exclusive dependence on oncogene fusions.

Cancer research
2015-04 | Journal article
Contributors: Saito M; Shimada Y; Shiraishi K; Sakamoto H; Tsuta K; Totsuka H; Chiku S; Ichikawa H; Kato M; Watanabe S et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Profiling of actionable gene alterations in ovarian cancer by targeted deep sequencing.

International journal of oncology
2015-04 | Journal article
Contributors: Takenaka M; Saito M; Iwakawa R; Yanaihara N; Saito M; Kato M; Ichikawa H; Shibata T; Yokota J; Okamoto A et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Upregulated Annexin A1 promotes cellular invasion in triple-negative breast cancer.

Oncology reports
2015-01 | Journal article
Contributors: Okano M; Kumamoto K; Saito M; Onozawa H; Saito K; Abe N; Ohtake T; Takenoshita S
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

Multiple metastatic malignant melanoma presenting intraluminal gallbladder bleeding.

International surgery
2014-09 | Journal article
Contributors: Onozawa H; Saito M; Yoshida S; Sakuma T; Matsuzaki M; Katagata N; Watanabe F; Yamaguchi Y; Takenoshita S; Nomizu T
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

A three-microRNA signature predicts responses to platinum-based doublet chemotherapy in patients with lung adenocarcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research
2014-08 | Journal article
Contributors: Saito M; Shiraishi K; Matsumoto K; Schetter AJ; Ogata-Kawata H; Tsuchiya N; Kunitoh H; Nokihara H; Watanabe S; Tsuta K et al.
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central

A mouse model of KIF5B-RET fusion-dependent lung tumorigenesis.

Carcinogenesis
2014-07 | Journal article
Contributors: Saito M; Ishigame T; Tsuta K; Kumamoto K; Imai T; Kohno T
Source: Self-asserted source
Motonobu Saito via Europe PubMed Central
Items per page:
Page 1 of 2

Peer review (18 reviews for 2 publications/grants)

Review activity for Esophagus. (7)
Review activity for Gastric cancer. (11)