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Employment (5)

Seoul National University College of Medicine: Seoul, KR

2013-11-01 to present | Research professor (Xenotransplantation Research Center)
Employment
Source: Self-asserted source
Jun-Seop Shin

Seoul National University Hospital: Jongno-gu, Seoul, KR

2009-04-01 to 2013-03-31 | Research professor (Xenotransplantation Research Center)
Employment
Source: Self-asserted source
Jun-Seop Shin

Korea Islet Transplantation Instititue: Seoul, KR

2006-01-16 to 2009-01-31 | Principal investigator
Employment
Source: Self-asserted source
Jun-Seop Shin

Vanderbilt University School of Medicine: Nashville, TN, US

2004-08-01 to 2005-10-31 | Postdoctoral fellow (Molecular physiology and biophysics)
Employment
Source: Self-asserted source
Jun-Seop Shin

Korea University: Seongbok-gu, Seoul, KR

2003-09-01 to 2004-07-31 | Postdoctoral fellow (Life Sciences)
Employment
Source: Self-asserted source
Jun-Seop Shin

Education and qualifications (3)

Korea University: Seongbok-gu, Seoul, KR

1997-09-01 to 2003-08-25 | Ph.D (Life Sciences)
Education
Source: Self-asserted source
Jun-Seop Shin

Korea University: Seongbok-gu, Seoul, KR

1995-09-01 to 1997-08-25 | MS (Life Sciences)
Education
Source: Self-asserted source
Jun-Seop Shin

Korea University: Seoul, KR

1991-03-01 to 1995-02-25 | BS (Genetic Engineering)
Education
Source: Self-asserted source
Jun-Seop Shin

Works (45)

Clinical Trial Protocol for Porcine Islet Xenotransplantation in South Korea

Diabetes & Metabolism Journal
2024-11-30 | Journal article
Contributors: Byung-Joon Kim; Jun-Seop Shin; Byoung-Hoon Min; Jong-Min Kim; Chung-Gyu Park; Hee-Jung Kang; Eung Soo Hwang; Won-Woo Lee; Jung-Sik Kim; Hyun Je Kim et al.
Source: check_circle
Crossref

Long‐term control of diabetes by tofacitinib‐based immunosuppressive regimen after allo islet transplantation in diabetic rhesus monkeys that rejected previously transplanted porcine islets

Xenotransplantation
2024-03 | Journal article
Contributors: Jong‐Min Kim; Seong‐Jun Kang; So‐Hee Hong; Hyunwoo Chung; Jun‐Seop Shin; Byoung‐Hoon Min; Hyun Je Kim; Jongwon Ha; Chung‐Gyu Park
Source: check_circle
Crossref

Long-term control of diabetes in a nonhuman primate by two separate transplantations of porcine adult islets under immunosuppression

American Journal of Transplantation
2021-11 | Journal article
Contributors: Jong-Min Kim; So-Hee Hong; Jun-Seop Shin; Byoung-Hoon Min; Hyun Je Kim; Hyunwoo Chung; Jiyeon Kim; Yoon Ji Bang; Sol Seo; Eung Soo Hwang et al.
Source: check_circle
Crossref

Long‐term porcine islet graft survival in diabetic non‐human primates treated with clinically available immunosuppressants

Xenotransplantation
2021-03 | Journal article
Contributors: Jong‐Min Kim; So‐Hee Hong; Hyunwoo Chung; Jun‐Seop Shin; Byoung‐Hoon Min; Hyun Je Kim; Jiyeon Kim; Eung Soo Hwang; Hee‐Jung Kang; Jongwon Ha et al.
Source: check_circle
Crossref

Galectin-4 Interaction with CD14 Triggers the Differentiation of Monocytes into Macrophage-like Cells via the MAPK Signaling Pathway

Immune Network
2019 | Journal article
Contributors: So-Hee Hong; Jun-Seop Shin; Hyunwoo Chung; Chung-Gyu Park
Source: check_circle
Crossref

Bioinformatic analysis of peripheral blood RNA-sequencing sensitively detects the cause of late graft loss following overt hyperglycemia in pig-to-nonhuman primate islet xenotransplantation

Scientific Reports
2019-12-11 | Journal article
Contributors: Hyun-Je Kim; Ji Hwan Moon; Hyunwoo Chung; Jun-Seop Shin; Bongi Kim; Jong-Min Kim; Jung-Sik Kim; Il-Hee Yoon; Byoung-Hoon Min; Seong-Jun Kang et al.
Source: check_circle
Crossref

JAK3 inhibitor-based immunosuppression in allogeneic islet transplantation in cynomolgus monkeys

Islets
2019-09-03 | Journal article
Contributors: Jong-Min Kim; Jun-Seop Shin; Byoung-Hoon Min; Seong-Jun Kang; Il-Hee Yoon; Hyunwoo Chung; Jiyeon Kim; Eung-Soo Hwang; Jongwon Ha; Chung-Gyu Park
Source: check_circle
Crossref

Delayed revascularization of islets after transplantation by IL‐6 blockade in pig to non‐human primate islet xenotransplantation model

Xenotransplantation
2018-01 | Journal article
Contributors: Byoung‐Hoon Min; Jun‐Seop Shin; Jong‐Min Kim; Seong‐Jun Kang; Hyun‐Je Kim; Il‐Hee Yoon; Su‐Kyoung Park; Ji‐won Choi; Min‐Suk Lee; Chung‐Gyu Park
Source: check_circle
Crossref

Pre‐clinical results in pig‐to‐non‐human primate islet xenotransplantation using anti‐CD40 antibody (2C10R4)‐based immunosuppression

Xenotransplantation
2018-01 | Journal article
Contributors: Jun‐Seop Shin; Jong‐Min Kim; Byoung‐Hoon Min; Il Hee Yoon; Hyun Je Kim; Jung‐Sik Kim; Yong‐Hee Kim; Seong‐Jun Kang; Jiyeon Kim; Hee‐Jung Kang et al.
Source: check_circle
Crossref

Failure of transplantation tolerance induction by autologous regulatory T cells in the pig‐to‐non‐human primate islet xenotransplantation model

Xenotransplantation
2016-07 | Journal article
Contributors: Jun‐Seop Shin; Byoung‐Hoon Min; Jong‐Min Kim; Jung‐Sik Kim; Il Hee Yoon; Hyun Je Kim; Yong‐Hee Kim; Jae Yool Jang; Hee Jung Kang; Dong‐Gyun Lim et al.
Source: check_circle
Crossref

Application of the Multiplex Cytokine Analysis to Monitor Xenogeneic Immune Responses to the Porcine Islet Graft in Non-Human Primate

Journal of Korean Medical Science
2013 | Journal article
Contributors: Yong-Hee Kim; Jung-Sik Kim; Il-Hee Yoon; Jun-Seop Shin; Jong-Min Kim; Sang-Joon Kim; Chung-Gyu Park
Source: check_circle
Crossref

Changes of N/L ratio and cortisol levels associated with experimental training in untrained rhesus macaques

2013 | Journal article
DOI:

10.1111/jmp.12023

EID:

2-s2.0-84872382052

Contributors: Lee, J.-I.; Shin, J.-S.; Lee, J.-E.; Jung, W.-Y.; Lee, G.; Kim, M.-S.; Park, C.-G.; Kim, S.-J.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Role of Regulatory T Cells in Transferable Immunological Tolerance to Bone Marrow Donor in Murine Mixed Chimerism Model

Journal of Korean Medical Science
2013 | Journal article
Contributors: Il-Hee Yoon; Yong-Hee Kim; You-sun Kim; Jun-Seop Shin; Chung-Gyu Park
Source: check_circle
Crossref

ELISPOT assay as a tool to study the effects of stem cells on cytokine secretion

2012 | Book
DOI:

10.1007/978-1-61779-325-7_9

EID:

2-s2.0-80555153901

Contributors: Shin, J.-S.; Park, C.-G.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

In situ application of hydrogel-type fibrin-islet composite optimized for rapid glycemic control by subcutaneous xenogeneic porcine islet transplantation

2012 | Journal article
DOI:

10.1016/j.jconrel.2012.07.018

EID:

2-s2.0-84865327127

Contributors: Kim, J.-S.; Lim, J.-H.; Nam, H.-Y.; Lim, H.-J.; Shin, J.-S.; Shin, J.-Y.; Ryu, J.-H.; Kim, K.; Kwon, I.-C.; Jin, S.-M. et al.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Reference values of hematology, chemistry, electrolytes, blood gas, coagulation time, and urinalysis in the Chinese rhesus macaques (Macaca mulatta)

2012 | Journal article
DOI:

10.1111/j.1399-3089.2012.00713.x

EID:

2-s2.0-84865371596

Contributors: Lee, J.-I.; Shin, J.-S.; Lee, J.-E.; Jung, W.-Y.; Lee, G.; Kim, M.-S.; Park, C.-G.; Kim, S.-J.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

In situ induction of dendritic cell-based T cell tolerance in humanized mice and nonhuman primates

2011 | Journal article
DOI:

10.1084/jem.20111242

EID:

2-s2.0-84862907881

Contributors: Jung, K.C.; Park, C.-G.; Jeon, Y.K.; Park, H.J.; Ban, Y.L.; Min, H.S.; Kim, E.J.; Kim, J.H.; Kang, B.H.; Park, S.P. et al.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Islet isolation from adult designated pathogen-free pigs: Use of the newer bovine nervous tissue-free enzymes and a revised donor selection strategy would improve the islet graft function

2011 | Journal article
DOI:

10.1111/j.1399-3089.2011.00677.x

EID:

2-s2.0-83755225192

Contributors: Jin, S.-M.; Shin, J.S.; Kim, K.S.; Gong, C.-H.; Park, S.K.; Kim, J.-S.; Yeom, S.-C.; Hwang, E.S.; Lee, C.T.; Kim, S.-J. et al.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Murine Mesenchymal Stem Cells Suppress T Lymphocyte Activation Through IL-2 Receptor α (CD25) Cleavage by Producing Matrix Metalloproteinases

2011 | Journal article
DOI:

10.1007/s12015-010-9203-9

EID:

2-s2.0-79955047654

Contributors: Park, M.-J.; Shin, J.-S.; Kim, Y.-H.; Hong, S.-H.; Yang, S.-H.; Shin, J.-Y.; Kim, S.-Y.; Kim, B.; Kim, J.-S.; Park, C.-G.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Novel culture technique involving an histone deacetylase inhibitor reduces the marginal islet mass to correct streptozotocin-induced diabetes

2011 | Journal article
DOI:

10.3727/096368910X557146

EID:

2-s2.0-80855164561

Contributors: Shin, J.-S.; Min, B.-H.; Lim, J.-Y.; Kim, B.-K.; Han, H.-J.; Yoon, K.-H.; Kim, S.-J.; Park, C.-G.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

The sequential combination of a JNK inhibitor and simvastatin protects porcine islets from peritransplant apoptosis and inflammation

2011 | Journal article
DOI:

10.3727/096368910X550170

EID:

2-s2.0-80053161046

Contributors: Jin, S.-M.; Kim, K.S.; Lee, S.-Y.; Gong, C.-H.; Park, S.K.; Shin, J.S.; Park, C.-G.; Kim, S.-J.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Effects of Tau on the activity of triose phosphate isomerase (TPI) in brain cells

2010 | Journal article
DOI:

10.1016/j.neuint.2010.03.014

EID:

2-s2.0-77952876615

Contributors: Park, S.-A.; Park, H.W.; Kim, N.-H.; Kim, Y.-H.; Kwak, M.-J.; Shin, J.-S.; Kim, C.-W.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Immunomodulation of delayed-type hypersensitivity responses by mesenchymal stem cells is associated with bystander T cell apoptosis in the draining lymph node

2010 | Journal article
DOI:

10.4049/jimmunol.0902723

EID:

2-s2.0-77958139165

Contributors: Lim, J.-H.; Kim, J.-S.; Yoon, I.-H.; Shin, J.-S.; Nam, H.-Y.; Yang, S.-H.; Kim, S.-J.; Park, C.-G.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

The change of cytokines in tear and blood after different pterygium operation

2010 | Journal article
DOI:

10.1016/j.cyto.2009.11.008

EID:

2-s2.0-73649143094

Contributors: Lee, J.K.; Song, Y.S.; Shin, J.S.; Kwon, Y.S.; Shin, M.S.; Kim, J.C.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

A fibrin gel carrier system for islet transplantation into kidney subcapsule

2009 | Journal article
DOI:

10.1007/s00592-008-0073-4

EID:

2-s2.0-69849105332

Contributors: Lim, J.-Y.; Min, B.-H.; Kim, B.-G.; Han, H.-J.; Kim, S.-J.; Kim, C.-W.; Han, S.-S.; Shin, J.-S.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Bortezomib can suppress activation of rapamycin-resistant memory T cells without affecting regulatory T-cell viability in non-human primates

2009 | Journal article
DOI:

10.1097/TP.0b013e3181bd7b3a

EID:

2-s2.0-74049101534

Contributors: Kim, J.-S.; Lee, J.-I.; Shin, J.-Y.; Kim, S.-Y.; Shin, J.-S.; Lim, J.-H.; Cho, H.-S.; Yoon, I.-H.; Kim, K.-H.; Kim, S.-J. et al.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Combinations of growth factors enhance the potency of islets in vitro

2009 | Journal article
DOI:

10.1097/MPA.0b013e318197a62e

EID:

2-s2.0-66149112524

Contributors: Lim, J.Y.; Min, B.H.; Kim, B.G.; Shin, J.-S.; Park, C.S.; Yoon, T.W.; Han, S.S.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Evaluation of human mesenchymal stem cell expansion without differentiation by 2-dimensional electrophoresis

2009 | Journal article
EID:

2-s2.0-84884635404

Contributors: Lee, B.-H.; Shin, J.-S.; Lim, Y.-H.; Kim, C.-W.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

A defect in glucose-induced dissociation of glucokinase from the regulatory protein in Zucker diabetic fatty rats in the early stage of diabetes

2007 | Journal article
DOI:

10.1152/ajpregu.00260.2006

EID:

2-s2.0-34147168086

Contributors: Shin, J.-S.; Torres, T.P.; Catlin, R.L.; Donahue, E.P.; Shiota, M.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Proteome analysis of serum from type 2 diabetics with nephropathy

2007 | Journal article
DOI:

10.1021/pr060489g

EID:

2-s2.0-33847395363

Contributors: Kim, H.-J.; Cho, E.-H.; Yoo, J.-H.; Kim, P.-K.; Shin, J.-S.; Kim, M.-R.; Kim, C.-W.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Proteome of mesenchymal stem cells

2007 | Journal article
DOI:

10.1002/pmic.200700089

EID:

2-s2.0-34548417199

Contributors: Hye, W.P.; Shin, J.-S.; Kim, C.-W.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Streptozotocin-induced diabetes can be reversed by hepatic oval cell activation through hepatic transdifferentiation and pancreatic islet regeneration

2007 | Journal article
DOI:

10.1038/labinvest.3700561

EID:

2-s2.0-34250349195

Contributors: Kim, S.; Shin, J.-S.; Kim, H.-J.; Fisher, R.C.; Lee, M.-J.; Kim, C.-W.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Transplantation of reconstructed corneal layer composed of corneal epithelium and fibroblasts on a lyophilized amniotic membrane to severely alkali-burned cornea

2006 | Journal article
DOI:

10.1111/j.1525-1594.2006.00237.x

EID:

2-s2.0-33744759568

Contributors: Jang, I.-K.; Ahn, J.-I.; Shin, J.-S.; Kwon, Y.-S.; Ryu, Y.-H.; Lee, J.-K.; Park, J.-K.; Song, K.-Y.; Yang, E.-K.; Kim, J.-C.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

In vitro trans-differentiation of rat mesenchymal cells into insulin-producing cells by rat pancreatic extract

2005 | Journal article
DOI:

10.1016/j.bbrc.2005.03.111

EID:

2-s2.0-17044401306

Contributors: Choi, K.S.; Shin, J.-S.; Lee, J.-J.; Kim, Y.S.; Kim, S.-B.; Kim, C.-W.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Inhibitory effect of rapamycin on corneal neovascularization in vitro and in vivo

2005 | Journal article
DOI:

10.1167/iovs.04-0753

EID:

2-s2.0-13944281689

Contributors: Kwon, Y.S.; Hong, H.S.; Kim, J.C.; Shin, J.S.; Son, Y.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Microcrystallization of α-lactalbumin

2005 | Journal article
DOI:

10.1016/j.jcrysgro.2005.05.012

EID:

2-s2.0-23144432048

Contributors: Lee, M.-J.; Kwon, J.-H.; Shin, J.-S.; Kim, C.-W.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Proteome analysis of rat pancreas induced by pancreatectomy

2005 | Journal article
DOI:

10.1016/j.bbapap.2005.02.003

EID:

2-s2.0-17444428065

Contributors: Shin, J.-S.; Lee, J.-J.; Lee, E.-J.; Kim, Y.-H.; Chae, K.-S.; Kim, C.-W.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Development and characterization of a rabbit corneal endothelial cell line

2004 | Journal article
DOI:

10.1007/s10384-004-0103-x

EID:

2-s2.0-6344236778

Contributors: Shin, J.S.; Jang, I.K.; Kim, C.W.; Kim, J.C.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Human β-defensin 2 is induced by interleukin-1β in the corneal epithelial cells

2004 | Journal article
EID:

2-s2.0-3242755069

Contributors: Shin, J.-S.; Kim, C.-W.; Kwon, Y.-S.; Kim, J.-C.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Isolation of ethanol-induced genes in pancreatic β-cells by representational difference analysis (RDA)

2004 | Journal article
EID:

2-s2.0-1642265739

Contributors: Shin, J.-S.; Kwon, Y.-S.; Lee, J.-J.; Kim, C.-W.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Characterization of streptozotocin-induced diabetic rats and pharmacodynamics of insulin formulations

2003 | Journal article
DOI:

10.1271/bbb.67.2396

EID:

2-s2.0-3242883645

Contributors: Lee, J.-J.; Yi, H.-Y.; Yang, J.-W.; Shin, J.-S.; Kwon, J.-H.; Kim, C.-W.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Enhancement of mouse pancreatic regeneration and HIT-T15 cell proliferation with rat pancreatic extract

2003 | Journal article
DOI:

10.1016/j.bbrc.2003.07.011

EID:

2-s2.0-0041829434

Contributors: Kim, Y.S.; Lee, J.-J.; Shin, J.-S.; Kim, H.-J.; Kim, C.-W.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Ethanol decreases basal insulin secretion from HIT-T15 cells

2002 | Journal article
DOI:

10.1016/S0024-3205(02)01484-4

EID:

2-s2.0-0037087076

Contributors: Shin, J.-S.; Lee, J.-J.; Yang, J.-W.; Kim, C.-W.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

In vitro model using mouse hepatocytes for study of alcohol stress

2001 | Journal article
DOI:

10.1271/bbb.65.1528

EID:

2-s2.0-0035403453

Contributors: Yang, J.-W.; Shin, J.-S.; Lee, J.-J.; Chang, H.-I.; Kim, C.-W.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

The effects of fetal bovine serum, epidermal growth factor, and retinoic acid on adult rat islets embedded in collagen gels

1999 | Journal article
EID:

2-s2.0-0032933083

Contributors: Shin, J.-S.; Chang, H.-I.; Sung, H.-C.; Kim, C.-W.
Source: Self-asserted source
Jun-Seop Shin via Scopus - Elsevier

Peer review (1 review for 1 publication/grant)

Review activity for Transplant immunology. (1)