Luis J. Fernández (0000-0001-5376-4440)

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Biography

Dr. Luis J. Fernandez received the MSc degree in Physics at the Univeristy of Zaragoza (Spain) in 2001. Then he joined the Transducers Science and Technology department at Twente Univeristy (The Netherlands) where he obtained the PhD degree in 2005 for the development of MEMS based power sensor for radio frequency signals. During the next 5 years he was involved in the development of low cost Micro Total Analysis Systems (TAS), microfluidic control elements and biosensors at CIC micro GUNE/IK4- Ikerlan Research Institute (Spain), becoming a formal partner of the centre. In 2010 he received the “Ramon y Cajal Fellowship” to join the University of Zaragoza (Spain) and lead scientific advances in the field of microfluidic devices for diagnostic and cell culture applications.
Luis Fernandez is currently Associate Professor at the University of Zaragoza, and CTO of Microliquid S.L., a company dedicated to the development and manufacturing of microfluidic devices for diagnostic and drug delivery applications.
He is also co-founder of the company BEONCHIP, dedicated to the commercialization of cell culture biomimetic devices based on microfluidics, and partner of EBERS MEDICAL TECHNOLOGY dedicated to the development and commercialization of tissue engineering and organ preservation equipment. Dr Fernandez has published 43 scientific papers with SCI, holds 25 patents (11 of them licensed or under exploitation) and 3 know-how transfers.

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Universidad de Zaragoza: Zaragoza, Aragón, ES

Researcher (Academic) (Ingeniería Mecánica)

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Luis J. Fernández

https://orcid.org/0000-0001-5376-4440

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Biography

Activities

Employment (5)

Universidad de Zaragoza: Zaragoza, Aragón, ES

Universidad de Zaragoza: Zaragoza, Aragón, ES

Instituto Universitario de Investigación en Ingenería de Aragón [I3A] : Zaragoza, Aragón, ES

Ikerlan Centro de Investigaciones Tecnológicas: Arrasate Mondragón, País Vasco, ES

Ikerlan Centro de Investigaciones Tecnológicas: Arrasate Mondragón, País Vasco, ES

Education and qualifications (2)

University of Twente: Twente, NL

University of Zaragoza: Zaragoza, ES

Funding (37)

DESARROLLO DE UN SISTEMA DE PRESERVACIÓN NORMOTÉRMICA CON CAPACIDAD DE MONITORIZACIÓN METABÓLICA NO INVASIVA (PRENOMON)

DESARROLLO DE UN SISTEMA BASADO EN MICROTECNOLOGÍA QUE INTEGRA CO-CULTUVOS CELULARES ORGANIZADOS, ANDAMIAJE ESPECÍFICO Y MICROSENSORES: HACIA UN MODELO IN-VITRO DE RIÑÓN.

DESARROLLO DE UN SISTEMA PORTATIL Y DE BAJO COSTE PARA LA DETECCIÓN DE CONTAMINANTES EN ALIMENTOS BASADO EN MICROFLUIDICA

Therapy Optimization in Glioblastoma: An Integrative Human Data-Based Approach Using Mathematical Models

CO-CULTIVO DE CÉLULAS RENALES EN DISPOSITIVO MICROFABRICADO: HACIA UN MODELO IN VITRO DE RIÑÓN

InForMed - An integrated pilot line for micro-fabricated medical devices (G.A. no. 662155)

INDUSTRIALIZACIÓN DE UN DISPOSITIVO MICROFLUIDICO PARA LA DETERMINACIÓN in situ Y CUANTITATIVA DEL CONSUMO DE DROGAS DE ABUSO EN SALIVA

Incidencia de los fenómenos de transporte en la hidrólisis enzimática y aplicación de mecánica de fluidos computacional en problemas de escalado (MIXING).

Estudio de respuesta bio-mecánica de dispositivos de B. BRAUN

Desarrollo de un sistema fluídico de diluciones

ESTUDIOS VOLUMÉTRICOS Y DE VIABILIDAD BIOLÓGICA DE LA VIRUTA ÓSEA OBTENIDA TRAS EL FRESADO A BAJA VELOCIDAD SIN IRRIGACIÓN

ESTUDIOS DE RESISTENCIA MECÁNICA DE MALLAS DE POLIÉSTERES (PLGA, PCL, PHB) FABRICADOS POR ELECTROSPINNING

Caracterizaion mecanica de hidrogeles

Desarrollo de un lector portátil para la determinación cuantitativa del abuso de drogas a través del análisis de saliva basado en el uso de microfluídica y sensores electroquímicos

DISEÑO, FABRICACIÓN Y CARACTERIZACIÓN DE CHIPS MICROFLUIDICOS PARA CULTIVO CELULAR QUE PERMITA LA INTEGRACIÓN DE GRADIENTES QUÍMICOS

FABRICACIÓN DE CHIPS MICROFLUÍDICOS MEDIANTE TÉCNICAS DE MOLDEO POR INYECCIÓN

3DFF three dimensions flex fluidicis

ACtivación del Titanio para Implantes BioAdaptados: ACTIBA

EFECTO DE LA MODIFICACIÓN SUPERFICIAL DE IMPLANTES DE TITANIO SOBRE LA OSTEOINTEGRACIÓN DE ESTOS EN UN MODELO DE CÓNDILO FEMORAL DE CONEJO

SEGUIMIENTO, ASESORÍA Y REDACCIÓN DE DOCUMENTOS TÉCNICOS PARA MICROLIQUID EN EL ÁMBITO DE LA FABRICACIÓN DE CARTUCHOS

DISEÑO,FABRICACION Y VALIDACION DE UNA PLATAFORMA MICROFLUICIDA PARA EL CULTIVO Y MONITORIZACION DE CELULAS EPITELIALES IN-VITRO EN CONDICIONES IN-VIVO

DESARROLLO DE UN SISTEMA DE CULTIVO CELULAR PARA CRIBADO DE ALTO RENDIMIENTO BASADO EN MICROFLUÍDICA

DESARROLLO DE UN SISTEMA EFICIENTE PARA LA CARACTERIZACIÓN DE SENSORES BASADOS EN CNT-FET

DESARROLLO DE ENCAPSULADOS VERSÁTILES Y DE BAJO COSTE PARA DISPOSITIVOS MICROFLUÍDICOS

DESARROLLO DE UN SISTEMA MICROFLUÍDICO DE CULTIVO CELULAR

DOTACION RAMON Y CAJAL 2010

SEGUIMIENTO, ASESORÍA Y REDACCIÓN DE DOCUMENTOS TÉCNICOS PARA PFF

1. Self-POCNAD - LoC prototype for parallel detection of multiple mRNA types from HPV virus for PoC cervical cancer screening

CIRCUITOS MICROFLUIDICOS INTEGRADOS CON ELEMENTOS ACTUADORES Y SENSORES

L4 - MICAS - Microtecnologías aplicadas a la salud

2. LABONFOIL - Integration of oleds, dry films and gelified reagents to fabricate laboratories on cards for food and environmental purposes

PORTFASTFLU - Portable automated test for fast detection and surveillance of influenza

OPTOBIOSENS - Microsistemas basados en micro/nanobiosensores fotónicos con integración microfluídica para aplicaciones en diagnóstico clínico

Fabricación de una matriz de pin-holes para el Módulo de Detección óptica

MICROGUNE

Desarrollo de un circuito microfluidico y del encapsulado de un sensor bioquímico

EMMA: Electro Mechanical Microcomponents for Precision Applications

Works (50 of 80)

Enabling cell recovery from 3D cell culture microfluidic devices for tumour microenvironment biomarker profiling

On the Simulation of Organ-on-Chip Cell Processes: Application to an In Vitro Model of Glioblastoma Evolution

Force spectroscopy-based simultaneous topographical and mechanical characterization to study polymer-to-polymer interactions in coated alginate microspheres

Modulation of Antioxidant Potential with Coenzyme Q10 Suppressed Invasion of Temozolomide-Resistant Rat Glioma In Vitro and In Vivo

A label free disposable device for rapid isolation of rare tumor cells from blood by ultrasounds

Activated human primary NK cells efficiently kill colorectal cancer cells in 3D spheroid cultures irrespectively of the level of PD-L1 expression

Soft Thermoplastic Elastomer for Easy and Rapid Spin-Coating Fabrication of Microfluidic Devices with High Hydrophilization and Bonding Performances

Tunable injectable alginate-based hydrogel for cell therapy in Type 1 Diabetes Mellitus

Alkynyl gold(I) complex triggers necroptosis via ROS generation in colorectal carcinoma cells

Combined in-silico and on-chip validation of pseudopalisade formation hypothesis in Glioblastoma

Glioblastoma on a microfluidic chip: Generating pseudopalisades and enhancing aggressiveness through blood vessel obstruction events

Multiwell capillarity-based microfluidic device for the study of 3D tumour tissue-2D endothelium interactions and drug screening in co-culture models

Preserving tumor heterogeneity: A microfluidic reactor for ex vivo preservation of colorectal cancer biopsies

SU–8 micro coriolis mass flow sensor

Thermoplastic elastomer with advanced hydrophilization and bonding performances for rapid (30 s) and easy molding of microfluidic devices

Development and characterization of a microfluidic model of the tumour microenvironment

Engineering glioblastoma microenvironment in a chip to study cell response

Hypoxia in gliomas: Opening therapeutical opportunities using a mathematical-based approach

Hypoxia in gliomas: Opening therapeutical opportunities using a mathematical-based approach

Improved anti-tumor activity of novel highly bioactive liposome-bound TRAIL in breast cancer cells

Prevention of Bone Loss in a Model of Postmenopausal Osteoporosis through Adrenomedullin Inhibition

TRAIL-coated lipid-nanoparticles overcome resistance to soluble recombinant TRAIL in non-small cell lung cancer cells

High-order TRAIL oligomer formation in TRAIL-coated lipid nanoparticles enhances DR5 cross-linking and increases antitumour effect against colon cancer