Personal information

Websites & social links

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Keywords

Drug Development, Modeling & Simulation, Biostatistics, Materials Science, Physical Virology, Self-assembly, Elasticity, Percolation Theory, Molecular Dynamics, Monte Carlo, Mathematica, Wolfram Language

Countries

United States

Activities

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Employment (6)

American Regent Inc: Shirley, NY, US

2022-04 to present | Senior Data Science Manager (Quantitative Sciences)
Employment
Source: Self-asserted source
Nicholas E. Brunk

VeriSIM Life: San Francisco, CA, US

2021-03 to 2022-04 | Senior Scientist (Modeling & Simulation)
Employment
Source: Self-asserted source
Nicholas E. Brunk

Wolfram Research Inc: Champaign, IL, US

2020-04 to 2022-04 | Scientific Software Developer
Employment
Source: Self-asserted source
Nicholas E. Brunk

Indiana University Bloomington: Bloomington, IN, US

2016-08 to 2021-05 | Research Assistant / Associate Instructor (Intelligent Systems Engineering)
Employment
Source: Self-asserted source
Nicholas E. Brunk

Indiana University Bloomington: Bloomington, IN, US

2015-01 to 2016-08 | Research Associate (Molecular and Cellular Biochemistry)
Employment
Source: Self-asserted source
Nicholas E. Brunk

Assembly Biosciences: Bloomington, US

2013-04 to 2014-12 | Laboratory Technician
Employment
Source: Self-asserted source
Nicholas E. Brunk

Education and qualifications (5)

Indiana University Bloomington: Bloomington, IN, US

2016-08 to present | Doctor of Philosophy (PhD) (Intelligent Systems Engineering - Nanoengineering)
Education
Source: Self-asserted source
Nicholas E. Brunk

Indiana University Bloomington: Bloomington, IN, US

2016-08 to 2019-05 | Master of Science (MS) (Intelligent Systems Engineering)
Education
Source: Self-asserted source
Nicholas E. Brunk

Indiana University Bloomington: Bloomington, IN, US

2014-05 to 2015-12 | Professional Science Master (PSM) (Biotechnology)
Education
Source: Self-asserted source
Nicholas E. Brunk

Indiana University Bloomington: Bloomington, IN, US

2008-08 to 2012-05 | Bachelor of Science (BS) (Physics)
Education
Source: Self-asserted source
Nicholas E. Brunk

Indiana University Bloomington: Bloomington, IN, US

2008-08 to 2012-05 | Bachelor of Arts (BA) (Mathematics)
Education
Source: Self-asserted source
Nicholas E. Brunk

Professional activities (2)

American Association of Pharmaceutical Scientists: Arlington, Virginia, US

2022 to present
Membership
Source: Self-asserted source
Nicholas E. Brunk

American Physical Society: College Park, MD, US

2017-10 to present
Membership
Source: Self-asserted source
Nicholas E. Brunk

Works (15)

Shape control of deformable charge-patterned nanoparticles

Physical Review E
2023-01-10 | Journal article
DOI: 10.1103/PhysRevE.107.014502
Contributors: Fanbo Sun; Nicholas E. Brunk; Vikram Jadhao
Source: check_circle
Crossref

Multilayered Ordered Protein Arrays Self-Assembled from a Mixed Population of Virus-like Particles

ACS Nano
2022-05-24 | Journal article
DOI: 10.1021/acsnano.1c11272
Contributors: Masaki Uchida; Nicholas E. Brunk; Nathasha D. Hewagama; Byeongdu Lee; Peter E. Prevelige, Jr.; Vikram Jadhao; Trevor Douglas
Source: check_circle
Crossref

In Silico Development of Combinatorial Therapeutic Approaches Targeting Key Signaling Pathways in Metabolic Syndrome

Pharmaceutical Research
2022-03-21 | Journal article
DOI: 10.1007/s11095-022-03231-z
Part of ISSN: 0724-8741
Part of ISSN: 1573-904X
Source: Self-asserted source
Nicholas E. Brunk

Binary Nanoparticle Superlattice Simulator

nanoHUB
2021 | Software
DOI: 10.21981/S6D9-TB56
Source: Self-asserted source
Nicholas E. Brunk

Combinatorial approaches using an AI/ML-driven drug development platform targeting insulin resistance, lipid dysregulation, and inflammation for the amelioration of metabolic syndrome in patients

2021-09-02 | Other
DOI: 10.1101/2021.09.01.458488
Contributors: Maksim Khotimchenko; Nicholas E. Brunk; Mark S. Hixon; Daniel M. Walden; Hypatia Hou; Kaushik Chakravarty; Jyotika Varshney
Source: check_circle
Crossref

Percolation Theory Reveals Biophysical Properties of Virus-like Particles

ACS Nano
2021-08-24 | Journal article
DOI: 10.1021/acsnano.1c01882
Contributors: Nicholas E. Brunk; Reidun Twarock
Source: check_circle
Crossref

Designing Surface Charge Patterns for Shape Control of Deformable Nanoparticles

Physical Review Letters
2020-12-10 | Journal article
DOI: 10.1103/PhysRevLett.125.248001
Contributors: Nicholas E. Brunk; JCS Kadupitiya; Vikram Jadhao
Source: check_circle
Crossref

Nanoparticle Shape Lab

2020-01-27 | Software
DOI: 10.21981/VPEC-Q251
Source: Self-asserted source
Nicholas E. Brunk

Computational studies of shape control of charged deformable nanocontainers

Journal of Materials Chemistry B
2019 | Journal article
DOI: 10.1039/C9TB01003C
Contributors: Nicholas E. Brunk; Vikram Jadhao
Source: check_circle
Crossref

Linker-Mediated Assembly of Virus-Like Particles into Ordered Arrays via Electrostatic Control

ACS Applied Bio Materials
2019-05-20 | Journal article
DOI: 10.1021/acsabm.9b00166
Contributors: Nicholas E. Brunk; Masaki Uchida; Byeongdu Lee; Masafumi Fukuto; Lin Yang; Trevor Douglas; Vikram Jadhao
Source: check_circle
Crossref

Nanoparticle Assembly Lab

Indiana University
2019-04 | Software
DOI: 10.21981/recv-rd32
Source: Self-asserted source
Nicholas E. Brunk

Competition between Normative and Drug-Induced Virus Self-Assembly Observed with Single-Particle Methods

Journal of the American Chemical Society
2019-01-23 | Journal article
DOI: 10.1021/jacs.8b10131
Contributors: Panagiotis Kondylis; Christopher J. Schlicksup; Nicholas E. Brunk; Jinsheng Zhou; Adam Zlotnick; Stephen C. Jacobson
Source: check_circle
Crossref

Nanosphere Electrostatics Lab

Indiana University
2018-07-05 | Software
DOI: 10.4231/d34x54j88
Source: Self-asserted source
Nicholas E. Brunk

Molecular jenga: the percolation phase transition (collapse) in virus capsids

Physical Biology
2018-06-06 | Journal article
DOI: 10.1088/1478-3975/aac194
Contributors: Nicholas E Brunk; Lye Siang Lee; James A Glazier; William Butske; Adam Zlotnick
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

A molecular breadboard: Removal and replacement of subunits in a hepatitis B virus capsid

Protein Science
2017 | Journal article
DOI: 10.1002/PRO.3265
WOSUID: WOS:000413668900005
Contributors: Stephen C. Jacobson; Joseph Che-Yen Wang; Adam Zlotnick; David Keifer; Martin F. Jarrold; Panagiotis Kondylis; Elizabeth Pierson; Nicholas Brunk; Daniel G. Haywood; Lye Siang Lee
Source: check_circle
Web of Science Researcher Profile Sync
grade
Preferred source (of 2)‎

Peer review (10 reviews for 3 publications/grants)

Review activity for Bulletin of mathematical biology. (5)
Review activity for Journal of physics. (2)
Review activity for Nanotechnology. (3)
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