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Long-Read RNA-sequencing reveals transcript-specific regulation in human-derived cortical neurons

2024-11-11 | Preprint
DOI: 10.1101/2024.11.08.622610
Contributors: Jishu Xu; Michaela Hörner; Elena Buena Atienza; Kalaivani Manibarathi; Maike Nagel; Stefan Hauser; Jakob Admard; Nicolas Casadei; Stephan Ossowski; Rebecca Schüle
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Unraveling Axonal Transcriptional Landscapes: Insights from iPSC-Derived Cortical Neurons and Implications for Motor Neuron Degeneration

2024-03-29 | Preprint
DOI: 10.1101/2024.03.26.586780
Contributors: Jishu Xu; Michaela Hörner; Maike Nagel; Perwin Perhat; Milena Korneck; Marvin Noß; Stefan Hauser; Ludger Schöls; Jakob Admard; Nicolas Casadei et al.
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Clinically approved immunomodulators ameliorate behavioral changes in a mouse model of hereditary spastic paraplegia type 11

Frontiers in Neuroscience
2024-02-16 | Journal article
DOI: 10.3389/fnins.2024.1299554
Part of ISSN: 1662-453X
Contributors: Michaela Hörner; Sandy Popp; Julien Branchu; Giovanni Stevanin; Frédéric Darios; Stephan Klebe; Janos Groh; Rudolf Martini
Source: Self-asserted source
Michaela Hörner
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Microglia-mediated demyelination protects against CD8+ T cell-driven axon degeneration in mice carrying PLP defects

Nature Communications
2023-10-30 | Journal article
DOI: 10.1038/s41467-023-42570-2
Contributors: Janos Groh; Tassnim Abdelwahab; Yogita Kattimani; Michaela Hörner; Silke Loserth; Viktoria Gudi; Robert Adalbert; Fabian Imdahl; Antoine-Emmanuel Saliba; Michael Coleman et al.
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CNS-associated T-lymphocytes in a mouse model of Hereditary Spastic Paraplegia type 11 (SPG11) are therapeutic targets for established immunomodulators

Experimental Neurology
2022-09 | Journal article
DOI: 10.1016/j.expneurol.2022.114119
Part of ISSN: 0014-4886
Contributors: Michaela Hörner; Janos Groh; Dennis Klein; Winfried Ilg; Ludger Schöls; Sara Dos Santos; Anna Bergmann; Stephan Klebe; Margaux Cauhape; Julien Branchu et al.
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Michaela Hörner
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Teriflunomide attenuates neuroinflammation-related neural damage in mice carrying human <i>PLP1</i> mutations

Journal of Neuroinflammation
2018 | Journal article
DOI: 10.1186/S12974-018-1228-Z
WOSUID: WOS:000437329000001
Contributors: Groh, Janos; Hoerner, Michaela; Martini, Rudolf
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Pathogenic inflammation in the CNS of mice carrying human <i>PLP1</i> mutations

Human Molecular Genetics
2016 | Journal article
DOI: 10.1093/HMG/DDW296
WOSUID: WOS:000397061300007
Contributors: Groh, Janos; Friedman, Hana C.; Orel, Nadiya; Ip, Chi Wang; Fischer, Stefan; Spahn, Irene; Schaeffner, Erik; Hoerner, Michaela; Stadler, David; Buttmann, Mathias et al.
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