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SciProfiles: 2621849

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Employment (1)

Univeristy College London: London, GB

2020-02-01 to present | Assistant Professor/Lecturer of Neuro-oncology (Great Ormond Street Institute of Child Health)
Employment
Source: Self-asserted source
Laura Donovan

Education and qualifications (1)

The Hospital for Sick Children: Toronto, ON, CA

2013-11-17 to 2020-02-02 | Neuro-oncology Fellow (Brain Tumour Research Centre)
Education
Source: Self-asserted source
Laura Donovan

Funding (4)

Combinatorial targeting of oncogene-driven childhood cancer

Grant
Stand up to Cancer, Cancer Research UK (London, GB)
Source: Self-asserted source
Laura Donovan

Decoupling clonal evolution of relapse medulloblastoma

Grant
GOSH NIHR (London, GB)
Source: Self-asserted source
Laura Donovan

Immunotherapy as a targeted low-impact treatment of paediatric brain cancers

Grant
Brain Canada, NeuroDevNet (Toronto, CA)
Source: Self-asserted source
Laura Donovan

Novel immunotherapeutic approaches for the treatment of primary, metastatic and recurrent medulloblastoma

Award
Great Ormond Street Hospital Charity (London, GB)
Source: Self-asserted source
Laura Donovan

Works (13)

Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma

Cell
2020-06 | Journal article
DOI: 10.1016/j.cell.2020.04.047
Part of ISSN: 0092-8674
Source: Self-asserted source
Laura Donovan

Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma

Nature Medicine
2020-05 | Journal article
DOI: 10.1038/s41591-020-0827-2
Part of ISSN: 1078-8956
Part of ISSN: 1546-170X
Source: Self-asserted source
Laura Donovan

Stalled developmental programs at the root of pediatric brain tumors

Nature Genetics
2019-12 | Journal article
DOI: 10.1038/s41588-019-0531-7
Part of ISSN: 1061-4036
Part of ISSN: 1546-1718
Source: Self-asserted source
Laura Donovan

Childhood cerebellar tumours mirror conserved fetal transcriptional programs

Nature
2019-08 | Journal article
DOI: 10.1038/s41586-019-1158-7
Part of ISSN: 0028-0836
Part of ISSN: 1476-4687
Source: Self-asserted source
Laura Donovan

A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases

Cell
2018-02 | Journal article
DOI: 10.1016/j.cell.2018.01.038
Part of ISSN: 0092-8674
Source: Self-asserted source
Laura Donovan

Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling

Nature
2018-01 | Journal article
DOI: 10.1038/nature25169
Part of ISSN: 0028-0836
Part of ISSN: 1476-4687
Source: Self-asserted source
Laura Donovan

Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma

Cancer Cell
2017-09 | Journal article
DOI: 10.1016/j.ccell.2017.08.003
Part of ISSN: 1535-6108
Source: Self-asserted source
Laura Donovan

Spatial heterogeneity in medulloblastoma

Nature Genetics
2017-05 | Journal article
DOI: 10.1038/ng.3838
Part of ISSN: 1061-4036
Part of ISSN: 1546-1718
Source: Self-asserted source
Laura Donovan

Divergent clonal selection dominates medulloblastoma at recurrence

Nature
2016-01 | Journal article
DOI: 10.1038/nature16478
Part of ISSN: 0028-0836
Part of ISSN: 1476-4687
Source: Self-asserted source
Laura Donovan

Expression of the chondroitin sulphate proteoglycan, NG2, in paediatric brain tumors.

Anticancer research
2014-12-01 | Journal article
PMID: 25503117
Source: Self-asserted source
Laura Donovan

CD133 glycosylation is enhanced by hypoxia in cultured glioma stem cells

International Journal of Oncology
2013-03 | Journal article
DOI: 10.3892/ijo.2013.1787
Part of ISSN: 1019-6439
Part of ISSN: 1791-2423
Source: Self-asserted source
Laura Donovan

CD133: holy of grail of neuro-oncology or promiscuous red-herring?

Cell Proliferation
2012-12 | Journal article
DOI: 10.1111/j.1365-2184.2012.00842.x
Part of ISSN: 0960-7722
Source: Self-asserted source
Laura Donovan

A Prominin-1-Rich Pediatric Glioblastoma: Biologic Behavior Is Determined by Oxygen Tension-Modulated CD133 Expression but Not Accompanied by Underlying Molecular Profiles

Translational Oncology
2012-06 | Journal article
DOI: 10.1593/tlo.11337
Part of ISSN: 1936-5233
Source: Self-asserted source
Laura Donovan

Peer review (1 review for 1 publication/grant)

Review activity for Cell. (1)
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