I am a chemical engineer that engaged into a research career in chemistry.
Early steps in research were given in 1999, the first year of the Chemical Engineering degree, when I joined the project "On the rocks" and started studying the influence of different rocks in the growth and crystal habit of inorganic crystals.
In 2006, this interest in crystals led me into an area that was then emerging: the design of new crystal forms of active pharmaceutical ingredients using crystal engineering principles, a rich and challenging area that was explored in both my Ms.C. (pre-Bologna) and Ph.D. projects. At this time, I joined Centro de Química Estrutural to develop my research.
Furthermore I have been dedicated to metallodrugs and metallopharmaceuticals, where mechanochemistry reveals to be a very powerful synthetic technique.
Since 2012, my main focus has been on developing BioMOFs, metal organic frameworks (MOFs) for pharmacological applications, such as controlled drug delivery.
The determination of stability, solubility and dissolution rates (via HPLC studies) of the novel pharmaceutical crystal forms as well as the establishment of structure-properties relationships are an important part of my work.
Over the years, I acquired expertise in Crystallography by extensively using single crystal and powder X-ray diffraction techniques in the screening and characterization of new crystal forms. More recently, I was given the opportunity to collect data at the European Synchrotron Radiation Facility (ESRF, Grenoble), one of the most powerful synchrotron radiation source in Europe, a very important step for the new challenge that I am embracing in my scientific life: structure solution from X-ray powder diffraction data. NMR crystallography and computational chemistry are also skills to be addressed in a near future.
I also have knowledge on differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), hot-stage microscopy (HSM), infrared spectroscopy.
Polymorphic screening; Design of multicomponent crystal forms and their solubility; Metallodrugs and metallopharmaceuticals; BioMOFs; Mechanochemistry; X-ray diffraction techniques; Crystallography
Papers in international periodicals with peer review 60 (+1 submitted)
Book chapters 6
Papers in national periodicals with peer review 3
Papers in conference proceedings 12
Oral communications 30
Poster communications 77