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Activities

Employment (5)

Vall d'Hebron Hospital Universitari: Barcelona, ES

1999-01-01 to 2023-05-26 | Faculty Attending, Ph.D. (Clinical Biochemistry)
Employment
Source: Self-asserted source
Rosanna Paciucci

Hospital del Mar: Barcelona, Catalunya, ES

1994-01-01 to 1998-09-30 | Postdoct Ph.D., Contract for Specific Project / Service. Project in Pancreas Cancer Research (Generalitat de Catalunya, IMIM, Unitat Biologia Celular i Molecular)
Employment
Source: Self-asserted source
Rosanna Paciucci

Ministerio de Educación, Cultura y Deporte: Santander, Cantabria, ES

1990-09-01 to 1993-06-30 | Postdoct, Ph.D. Scholarship from Ministerio de Educación, Cultura y Deporte (Universidad de Cantabria, Facultad Medicina, Dpto Biología Molecular)
Employment
Source: Self-asserted source
Rosanna Paciucci

The Mount Sinai Hospital: New York, NY, US

1982-07-01 to 1984-07-31 | Research Assistant, Lab. of Tumor Pharmacology, Fellowship from the Neoplastic Disease Dept. (Medical School, Neoplastic Diseases)
Employment
Source: Self-asserted source
Rosanna Paciucci

Policlinico Umberto I: Rome, IT

1979 to 1982 | Research Assistant, Lab. Immunology (Policlinico Umberto I, II Surgical Clinics, Renal Transplants)
Employment
Source: Self-asserted source
Rosanna Paciucci

Education and qualifications (4)

Ministry of Education: Madrid, ES

2006 to present | Specialist in Clinical Biochemistry (Clinical Biochemistry)
Qualification
Source: Self-asserted source
Rosanna Paciucci

New York University Langone Medical Center: New York City, New York, US

1984-09-01 to 1990-06-22 | Ph. D. Cellular and Molecular Biology (Pathology, Scholarship from NYU)
Education
Source: Self-asserted source
Rosanna Paciucci

New York University Langone Medical Center: New York City, New York, US

1984-09-01 to 1986-06-10 | MS in Cellular and Molecular Biology (Pathology, Scholarship from NYU )
Education
Source: Self-asserted source
Rosanna Paciucci

Sapienza University of Rome: Rome, Lazio, IT

1977-10-01 to 1982-06-20 | Bachelor/ Laurea in Biologia (Faculty of Biology)
Education
Source: Self-asserted source
Rosanna Paciucci

Professional activities (6)

Ministerio de Ciencia y Tecnología : Madrid, ES

2002 to present | Expert in Biomedicine, evaluator of research projects in cancer (AEI Agencia Estatal de Investigación, previously ANEP)
Invited position
Source: Self-asserted source
Rosanna Paciucci

Autonoma University: Barcelona, Catalunya, ES

1998 to present | Ph.D. Thesis Director of 5 students: Patricia Benedit, Mariano Hurtado, Veronica Cánovas, Valentina Maggio, Emily Toscano (in progress) (Faculty of Medicine, Dept. Cellular and Molecular Biology)
Invited position
Source: Self-asserted source
Rosanna Paciucci

Autonoma University: Barcelona, Catalunya, ES

2014 to 2019 | Teacher and coordinator of the Oncology module (Master in Translational Research, at the Vall Hebron Research Institute, Vall Hebron Hospital)
Service
Source: Self-asserted source
Rosanna Paciucci

University of Barcelona: Barcelona, Catalunya, ES

1998 to 2011 | Ph.D. Thesis Director of 5 students: Víctor Manuel Díaz, Anna Santamaría, Lide Alaña, Neus Marqués, Valentí Gómez (Faculty of Biology, Dept. Genetics and Biochemistry)
Invited position
Source: Self-asserted source
Rosanna Paciucci

University of Barcelona: Barcelona, Catalunya, ES

1999 to 2007 | Teaching professor (invited every other year) (Faculty of Biology, Dept. Genetics, Course in Genetics of Cancer)
Service
Source: Self-asserted source
Rosanna Paciucci

Scientific Committee, VHIR, Vall d'Hebron Hospital: Barcelona, ES

2003 to 2005 | Appointed Representative for the 'Biomedical Research Unit', VHIR (Vall Hebron Research Institute )
Invited position
Source: Self-asserted source
Rosanna Paciucci

Funding (19)

Early detection and tailored therapy for hormone-naïve metastatic prostate cancer patients.

2019-06 to 2019-06 | Grant
Ministerio Ciencia, Innovación y Universidades, Sudireccion Evaluación y Fomento de la Investigación (Madrid, Madrid, ES)
GRANT_NUMBER:

PI19/01726

Source: Self-asserted source
Rosanna Paciucci

Early detection of recurrence for a personalized therapy of hormone-naïve prostate cancer patients with metastatic disease

2018-01 to 2022-12 | Grant
Ministerio de Ciencia, Innovación y Universidades (Madrid, Madrid, ES)
GRANT_NUMBER:

RTI 2018-096055-B-100

Source: Self-asserted source
Rosanna Paciucci

Translational reprogramming in the resistant cancer.

2017 to 2019 | Award
Agència de Gestió d'Ajuts Universitaris i de Recerca (Barcelona, Catalunya, ES) (Barcelona, ES)
GRANT_NUMBER:

SGR/2017-2019/PACIUCCI/MOROTE

Source: Self-asserted source
Rosanna Paciucci

The therapeutic stress generates resistance in prostate cancer stem cells: search for predictive markers and therapeutic targets

2015-01 to 2017-12 | Grant
Ministerio de Economía y Competitividad (Madrid, Madrid, ES)
GRANT_NUMBER: SAF2014-59958-R
Source: Self-asserted source
Rosanna Paciucci

The therapeutic stress as generator of resistance in cancer stem cells.

2014-01 to 2018-12 | Salary award
Industex S.A.. (Barcelona, Catalunya, ES)
Source: Self-asserted source
Rosanna Paciucci

Translation reprogramming and mitotic control

2014-01 to 2016-01 | Grant
Agència de Gestió d'Ajuts Universitaris i de Recerca (Barcelona, Catalunya, ES)
GRANT_NUMBER:

AGAUR, 2014-SGR733

Source: Self-asserted source
Rosanna Paciucci

Translational reprogramming in cancer: identification of markers of aggressive metastatic tumors. (BA12/00078)

2012-09 to 2012-12 | Grant
Ministry of Health and Economy Health Strategic Action 2012, Spain (Madrid, ES)
Source: Self-asserted source
Rosanna Paciucci

The oncogene PTOV1 regulates protein translation and Notch signaling. A study of its relevance in cancer

2012-01 to 2014-12 | Grant
MINISTERIO DE ECONOMIA y COMPETITIVIDAD PLAN NACIONAL de I+D+i 2008-2011 Subprograma de Proyectos de Investigación Fundamental (Madrid, Madrid, ES)
GRANT_NUMBER:

SAF 2011-30496

Source: Self-asserted source
Rosanna Paciucci

Translational reprogramming can mediate oncogenesis

2010-01 to 2012-12 | Grant
Fundación Mutua Madrileña; Fundación Mutua Madrileña (Madrid, Madrid, ES)
GRANT_NUMBER:

Fundación Mutua Madrileña

Source: Self-asserted source
Rosanna Paciucci

Cancer, cellular signaling and ubiquitination

2009 to 2014 | Grant
Direcció General de Recerca, Generalitat de Catalunya (Barcelona, ES)
Source: Self-asserted source
Rosanna Paciucci

Modulation of proliferation and tumor progression mediated by PTOV1: interaction with the Notch pathway and expression in tumor tissues-array

2008-01 to 2010-12 | Grant
Instituto de Salud Carlos III (Madrid, Madrid, ES)
GRANT_NUMBER: PI080547
Source: Self-asserted source
Rosanna Paciucci
grade
Preferred source (of 2)‎

Proliferation and tumor progression by PTOV1: studying the functional interaction with the Notch pathway and its expression in tumor tissues-array.

2008-01 to 2010-12 | Grant
Ministry of Science and Innovation Spain (Madrid, Madrid, ES)
GRANT_NUMBER:

SAF2008-03936

Source: Self-asserted source
Rosanna Paciucci

Translational Oncology of hormone-dependent tumors

2007-01 to 2009-12 | Grant
Ministerio de Sanidad, Consumo y Bienestar Social (Madrid, Madrid, ES)
GRANT_NUMBER:

Rd06/0020/0058

Source: Self-asserted source
Rosanna Paciucci

Function of the complex PTOV1/Flotillin-1/RACK1 in the proliferation and tumor progression. Its validation on human cancer tissue-arrays and in the transgenic TRAMP model of prostate cancer

2005-01 to 2007-12 | Grant
Ministerio de Educación, Cultura y Deporte (Madrid, Madrid, ES)
GRANT_NUMBER:

SAF2005-05848

Source: Self-asserted source
Rosanna Paciucci

Functional characterization of the PTOV1-flotillin-1 complex in the modulation of cancer cell proliferation: mitotic control and interaction with the Notch pathway

2005-01 to 2007-12 | Grant
Fundació Pi i Sunyer Foundation la Marató de TV3 (Barcelona, Catalunya, ES)
GRANT_NUMBER: 052610
Source: Self-asserted source
Rosanna Paciucci

PTOV1, a new protein implicated in prostate cancer and PIN. Study of its usefulness as tumor marker

2001-01 to 2003-12 | Grant
Asociación Española de Urología (Madrid, Madrid, ES)
Source: Self-asserted source
Rosanna Paciucci

Anàlisi del paper dels activadors del plasminogen (PAs) a la nefropatia diabètica. Establiment del model d'inducció experimental de diabetis a ratolins null pels PAs

1999 to 2001 | Grant
Institut d’Investigacions Biomèdiques August Pi i Sunyer, Universitat de Barcelona (Barcelona, ES)
GRANT_NUMBER: 992910
Source: Self-asserted source
Rosanna Paciucci

MECANISMOS MOLECULARES DE SOBREEXPRESION DE LAS PROTEA SAS ACTIVADORAS DEL PLASMINOGENO EN LOS TUMORES DEL PAN CREAS EXOCRINO. IMPLICACION DE LOS GENES K-RAS Y P53 EN LA PROGRESION TUMORAL MEDIADA POR PROTEASAS

1997-12 to 1999-12 | Grant
MINISTRY OF EDUCATION AND CULTURE (MADRID, SPAIN, ES)
GRANT_NUMBER:

SAF97-0084

Source: Self-asserted source
Rosanna Paciucci

Diferenciació cel.lular i metastàsis

1995 to 1997 | Grant
Institut d’Investigacions Biomèdiques August Pi i Sunyer, Universitat de Barcelona (Barcelona, ES)
GRANT_NUMBER: Marató TV3 1994
Source: Self-asserted source
Rosanna Paciucci

Works (46)

Dasatinib-Induced Chylothorax: A Clinical Laboratory's Perspective.

EJIFCC
2023-04-18 | Journal article
Contributors: Gea CS; Victor Martin-Riera; Ruiz ARG; Ferrer-Costa R; Paciucci R (Author); Ramirez-Serra C (Author)
Source: Self-asserted source
Rosanna Paciucci

Rapid and accurate method for quantifying busulfan in plasma samples by isocratic liquid chromatography-tandem mass spectrometry (LC-MS/MS).

Advances in Laboratory Medicine
2022-06-13 | Journal article
Contributors: Yolanda Villena-Ortiz; Castellote-Bellés L; Luisa María Martínez Sánchez; Benítez-Carabante MI; Miarons M; Vima-Bofarull J; Barquin-DelPino R; Paciucci R; Rodríguez-Frías F; Ferrer-Costa R et al.
Source: Self-asserted source
Rosanna Paciucci

Recovery of serum testosterone levels is an accurate predictor of survival from COVID-19 in male patients

[BMC Medicine]
2022-03-29 | Journal article
Source: Self-asserted source
Rosanna Paciucci

RNA-binding proteins: underestimated contributors in tumorigenesis.

Seminars in Cancer Biology
2022-02-02 | Journal article
OTHER-ID:

S1044-579X(22)00020-7

Source: Self-asserted source
Rosanna Paciucci

STAT3 inhibition with galiellalactone effectively targets the prostate cancer stem-like cell population

Scientific Reports
2020-12 | Journal article
Part of ISSN: 2045-2322
Source: Self-asserted source
Rosanna Paciucci

C1 esterase inhibitor and the contact system in COVID‐19

British Journal of Haematology
2020-08 | Journal article
Part of ISSN: 0007-1048
Part of ISSN: 1365-2141
Source: Self-asserted source
Rosanna Paciucci

Insights into new mechanisms and models of cancer stem cell multidrug resistance

Seminars in Cancer Biology
2020-02 | Journal article
Part of ISSN: 1044-579X
Source: Self-asserted source
Rosanna Paciucci

A novel DNA-binding motif in prostate tumor overexpressed-1 (PTOV1) required for the expression of ALDH1A1 and CCNG2 in cancer cells

Cancer Letters
2019-06 | Journal article
Part of ISSN: 0304-3835
Source: Self-asserted source
Rosanna Paciucci

Autophagy inhibition as a promising therapeutic target for laryngeal cancer

Carcinogenesis
2019-05-03 | Journal article
Part of ISSN: 0143-3334
Part of ISSN: 1460-2180
Source: Self-asserted source
Rosanna Paciucci

Expression patterns and bioinformatic analysis of miR-1260a and miR-1274a in Prostate Cancer Tunisian patients

Molecular Biology Reports
2018-12 | Journal article
Part of ISSN: 0301-4851
Part of ISSN: 1573-4978
Source: Self-asserted source
Rosanna Paciucci

Silencing of the transcriptional factor ZEB1 alters the steroidogenic pathway, and increases the concentration of testosterone and DHT in DU145 cells

Oncology Reports
2018-11-26 | Journal article
Part of ISSN: 1021-335X
Part of ISSN: 1791-2431
Source: Self-asserted source
Rosanna Paciucci

miR-99a reveals two novel oncogenic proteins E2F2 and EMR2 and represses stemness in lung cancer

Cell Death & Disease
2017-10 | Journal article
Part of ISSN: 2041-4889
Source: Self-asserted source
Rosanna Paciucci

Prostate Tumor Overexpressed-1 (PTOV1) promotes docetaxel-resistance and survival of castration resistant prostate cancer cells

Oncotarget
2017-08-29 | Journal article
Part of ISSN: 1949-2553
Source: Self-asserted source
Rosanna Paciucci

The role of prostate tumor overexpressed 1 in cancer progression

Oncotarget
2017-02-14 | Journal article
Part of ISSN: 1949-2553
Source: Self-asserted source
Rosanna Paciucci

Targeted proteomics in urinary extracellular vesicles identifies biomarkers for diagnosis and prognosis of prostate cancer

Oncotarget
2017-01-17 | Journal article
Part of ISSN: 1949-2553
Source: Self-asserted source
Rosanna Paciucci

Prostate tumor OVerexpressed-1 (PTOV1) down-regulates HES1 and HEY1 notch targets genes and promotes prostate cancer progression

Molecular Cancer
2014 | Journal article
Part of ISSN: 1476-4598
Source: Self-asserted source
Rosanna Paciucci

SPARC mediates metastatic cooperation between CSC and non-CSC prostate cancer cell subpopulations

Molecular Cancer
2014-12 | Journal article
Part of ISSN: 1476-4598
Source: Self-asserted source
Rosanna Paciucci

Regulation of protein translation and c-Jun expression by prostate tumor overexpressed 1

Oncogene
2014-02 | Journal article
Part of ISSN: 0950-9232
Part of ISSN: 1476-5594
Source: Self-asserted source
Rosanna Paciucci

Ribosomal proteins as novel players in tumorigenesis

Cancer and Metastasis Reviews
2013-12-28 | Journal article
Part of ISSN: 0167-7659
Part of ISSN: 1573-7233
Source: Self-asserted source
Rosanna Paciucci

Oxidative stress and cancer: An overview

Ageing Research Reviews
2013-01 | Journal article
Part of ISSN: 1568-1637
Source: Self-asserted source
Rosanna Paciucci

Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells

Journal of Clinical Investigation
2012-05-01 | Journal article
Part of ISSN: 0021-9738
Source: Self-asserted source
Rosanna Paciucci

Cancer, Senescence, and Aging: Translation from Basic Research to Clinics

Journal of Aging Research
2011 | Journal article
Part of ISSN: 2090-2212
Source: Self-asserted source
Rosanna Paciucci

PTOV1 is overexpressed in human high-grade malignant tumors

Virchows Archiv
2011-03 | Journal article
Part of ISSN: 0945-6317
Part of ISSN: 1432-2307
Source: Self-asserted source
Rosanna Paciucci

Regulation of Aurora B Kinase by the Lipid Raft Protein Flotillin-1

Journal of Biological Chemistry
2010-07 | Journal article
Part of ISSN: 0021-9258
Source: Self-asserted source
Rosanna Paciucci

PTOV1 Expression Predicts Prostate Cancer in Men with Isolated High-Grade Prostatic Intraepithelial Neoplasia in Needle Biopsy

Clinical Cancer Research
2008-05-01 | Journal article
Part of ISSN: 1078-0432
Part of ISSN: 1557-3265
Source: Self-asserted source
Rosanna Paciucci

Activation of the epidermal growth factor signalling pathway by tissue plasminogen activator in pancreas cancer cells

Gut
2007-04-05 | Journal article
Part of ISSN: 0017-5749
Source: Self-asserted source
Rosanna Paciucci

Requirement of the enzymatic and signaling activities of plasmin for phorbol-ester-induced scattering of colon cancer cells

Experimental Cell Research
2006-07 | Journal article
Part of ISSN: 0014-4827
Source: Self-asserted source
Rosanna Paciucci

PTOV1 Enables the Nuclear Translocation and Mitogenic Activity of Flotillin-1, a Major Protein of Lipid Rafts

Molecular and Cellular Biology
2005-03 | Journal article
Part of ISSN: 0270-7306
Part of ISSN: 1098-5549
Source: Self-asserted source
Rosanna Paciucci

Intracellular Clusterin Induces G2-M Phase Arrest and Cell Death in PC-3 Prostate Cancer Cells1

Cancer Research
2004-09-01 | Journal article
Part of ISSN: 0008-5472
Part of ISSN: 1538-7445
Source: Self-asserted source
Rosanna Paciucci

Specific interaction of tissue-type plasminogen activator (t-PA) with annexin II on the membrane of pancreatic cancer cells activates plasminogen and promotes invasion in vitro

Gut
2004-07-01 | Journal article
Part of ISSN: 0017-5749
Source: Self-asserted source
Rosanna Paciucci

[Antimitogenic effect of Pygeum africanum extracts on human prostatic cancer cell lines and explants from benign prostatic hyperplasia].

Archivos espanoles de urologia
2003-05-01 | Journal article
Source: Self-asserted source
Rosanna Paciucci

PTOV-1, a Novel Protein Overexpressed in Prostate Cancer, Shuttles between the Cytoplasm and the Nucleus and Promotes Entry into the S Phase of the Cell Division Cycle

The American Journal of Pathology
2003-03 | Journal article
Part of ISSN: 0002-9440
Source: Self-asserted source
Rosanna Paciucci

Tissue plasminogen activator is required for the growth, invasion, and angiogenesis of pancreatic tumor cells

Gastroenterology
2002-03 | Journal article
Part of ISSN: 0016-5085
Source: Self-asserted source
Rosanna Paciucci

PTOV1, a novel protein overexpressed in prostate cancer containing a new class of protein homology blocks

Oncogene
2001-03 | Journal article
Part of ISSN: 0950-9232
Part of ISSN: 1476-5594
Source: Self-asserted source
Rosanna Paciucci

Activation of the Urokinase Plasminogen Activator/Urokinase Plasminogen Activator Receptor System and Redistribution of E-Cadherin Are Associated with Hepatocyte Growth Factor-Induced Motility of Pancreas Tumor Cells Overexpressing Met

The American Journal of Pathology
1998-07 | Journal article
Part of ISSN: 0002-9440
Source: Self-asserted source
Rosanna Paciucci

Protein Kinase C-α Activity Inversely Modulates Invasion and Growth of Intestinal Cells

Journal of Biological Chemistry
1998-06 | Journal article
Part of ISSN: 0021-9258
Source: Self-asserted source
Rosanna Paciucci

The plasminogen activator system in pancreas cancer: role of t-PA in the invasive potential in vitro

Oncogene
1998-02 | Journal article
Part of ISSN: 0950-9232
Part of ISSN: 1476-5594
Source: Self-asserted source
Rosanna Paciucci

Role of UEV-1, an Inactive Variant of the E2 UbiquitinConjugating Enzymes, in In Vitro Differentiation and Cell Cycle Behavior of HT-29-M6 Intestinal Mucosecretory Cells

Molecular and Cellular Biology
1998-01 | Journal article
Part of ISSN: 0270-7306
Part of ISSN: 1098-5549
Source: Self-asserted source
Rosanna Paciucci

Isolation of tissue-type plasminogen activator, cathepsin H, and non-specific cross-reacting antigen from SK-PC-1 pancreas cancer cells using subtractive hybridization

FEBS Letters
1996-04-29 | Journal article
Part of ISSN: 0014-5793
Source: Self-asserted source
Rosanna Paciucci

Role of 300 kDa complexes as intermediates in tubulin folding and dimerization: characterization of a 25 kDa cytosolic protein involved in the GTP-dependent release of monomeric tubulin

Biochemical Journal
1994-07-01 | Journal article
Part of ISSN: 0264-6021
Part of ISSN: 1470-8728
Source: Self-asserted source
Rosanna Paciucci

Binding of Heat-Shock Protein 70 (hsp70) to Tubulin

Archives of Biochemistry and Biophysics
1994-05 | Journal article
Part of ISSN: 0003-9861
Source: Self-asserted source
Rosanna Paciucci

Incorporation of tubulin subunits into dimers requires GTP hydrolysis.

Journal of cell science
1993-10-01 | Journal article
PMID: 8282766
Source: Self-asserted source
Rosanna Paciucci

Dissection of the mouse N-ras gene upstream regulatory sequences and identification of the promoter and a negative regulatory element

Molecular and Cellular Biology
1991-03 | Journal article
Part of ISSN: 0270-7306
Part of ISSN: 1098-5549
Source: Self-asserted source
Rosanna Paciucci

Characterization of unr; a gene closely linked to N-ras.

Nucleic acids research
1990-08-01 | Journal article
PMID: 2204029
Source: Self-asserted source
Rosanna Paciucci

[Preliminary results of acyclovir treatment of herpetic infections in organ transplant patients].

Giornale italiano di chemioterapia
1984-01-01 | Journal article
PMID: 6381206
Source: Self-asserted source
Rosanna Paciucci

[T-suppressors in subjects treated with renal transplantation. Preliminary data]

Minerva chirurgica
1980-05-01 | Journal article
PMID: 6450336
Source: Self-asserted source
Rosanna Paciucci

Peer review (1 review for 1 publication/grant)

Review activity for EMBO molecular medicine. (1)