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Works (20)

Nilotinib attenuates vascular pathology in experimental cerebral malaria

Blood Advances
2025-02-24 | Journal article
DOI: 10.1182/bloodadvances.2024015364
Contributors: Luana Dos Santos Ortolan; Priyanka Bansal; Veronica I Primavera; Rodrigo J.R.X. Freitas; Ling Wei; Sabrina Epiphanio; Alexis Kaushansky; Joe Douglas Smith
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Systems-level reconstruction of kinase phosphosignaling networks regulating endothelial barrier integrity using temporal data

npj Systems Biology and Applications
2024-11-16 | Journal article
DOI: 10.1038/s41540-024-00468-9
Contributors: Ling Wei; John D. Aitchison; Alexis Kaushansky; Fred D. Mast
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Systems-level reconstruction of kinase phosphosignaling networks regulating endothelial barrier integrity using temporal data

2024-08-05 | Preprint
DOI: 10.1101/2024.08.01.606198
Contributors: Ling Wei; John D. Aitchison; Alexis Kaushansky; Fred D. Mast
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Interrogating endothelial barrier regulation by temporally resolved kinase network generation

Life Science Alliance
2024-05 | Journal article
DOI: 10.26508/lsa.202302522
Contributors: Ling Wei; Selasi Dankwa; Kamalakannan Vijayan; Joseph D Smith; Alexis Kaushansky
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Using machine learning to dissect host kinases required forLeishmaniainternalization and development

2024-05-16 | Preprint
DOI: 10.1101/2024.05.16.593986
Contributors: Ling Wei; Umaru Barrie; Gina M. Aloisio; Francis T. H. Khuong; Nadia Arang; Arani Datta; Alexis Kaushansky; Dawn M. Wetzel
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Exploring Subsite Selectivity within Plasmodium vivax N-Myristoyltransferase Using Pyrazole-Derived Inhibitors

Journal of Medicinal Chemistry
2024-05-09 | Journal article
DOI: 10.1021/acs.jmedchem.4c00168
Contributors: Diego Rodríguez-Hernández; Michael K. Fenwick; Rachael Zigweid; Banumathi Sankaran; Peter J. Myler; Per Sunnerhagen; Alexis Kaushansky; Bart L. Staker; Morten Grøtli
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Protocol for assembling and implementing a partially automated system for rearing and handling Anopheles stephensi mosquitoes

STAR Protocols
2023-12 | Journal article
DOI: 10.1016/j.xpro.2023.102621
Contributors: Zephyr Pitre; Tess Seltzer; Cecilia Kalthoff; Maria Benitez-Cortez; Conrad Yee; Elizabeth K.K. Glennon; Veronica I. Primavera; Alexis Kaushansky
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Multiple Receptor Tyrosine Kinases Regulate Dengue Infection of Hepatocytes

2023-07-30 | Preprint
DOI: 10.1101/2023.07.30.549949
Contributors: Natasha M. Bourgeois; Ling Wei; Nhi N. T. Ho; Maxwell L. Neal; Denali Seferos; Tinotenda Tongogara; Fred D. Mast; John D. Aitchison; Alexis Kaushansky
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Liver-stage Plasmodium infection tunes clinical outcomes

Trends in Parasitology
2023-05 | Journal article
DOI: 10.1016/j.pt.2023.03.004
Contributors: Alexis Kaushansky; Nana Minkah
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Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality

Journal of Cell Biology
2022-11-07 | Journal article
DOI: 10.1083/jcb.202011050
Contributors: Arti T. Navare; Fred D. Mast; Jean Paul Olivier; Thierry Bertomeu; Maxwell L. Neal; Lindsay N. Carpp; Alexis Kaushansky; Jasmin Coulombe-Huntington; Mike Tyers; John D. Aitchison
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Interrogating endothelial barrier regulation by temporally resolved kinase network generation

2022-09-20 | Preprint
DOI: 10.1101/2022.09.19.508598
Contributors: Ling Wei; Selasi Dankwa; Kamalakannan Vijayan; Joseph D. Smith; Alexis Kaushansky
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Cyclosporine Induces Fenestra-Associated Injury in Human Renal Microvessels In Vitro

ACS Biomaterials Science & Engineering
2022-01-10 | Journal article
DOI: 10.1021/acsbiomaterials.1c00986
Contributors: Ryan J. Nagao; Raluca Marcu; Yu Jung Shin; Daniel Lih; Jun Xue; Nadia Arang; Ling Wei; Shreeram Akilesh; Alexis Kaushansky; Jonathan Himmelfarb et al.
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Host-targeted Interventions as an Exciting Opportunity to Combat Malaria

Chemical Reviews
2021-09-08 | Journal article
DOI: 10.1021/acs.chemrev.1c00062
Contributors: Kamalakannan Vijayan; Ling Wei; Elizabeth K. K. Glennon; Christa Mattocks; Natasha Bourgeois; Bart Staker; Alexis Kaushansky
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A systems-level gene regulatory network model for Plasmodium falciparum

Nucleic Acids Research
2021-05-21 | Journal article
DOI: 10.1093/nar/gkaa1245
Contributors: Maxwell L Neal; Ling Wei; Eliza Peterson; Mario L Arrieta-Ortiz; Samuel A Danziger; Nitin S Baliga; Alexis Kaushansky; John D Aitchison
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Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality

Journal of Cell Biology
2020-10-05 | Journal article
DOI: 10.1083/jcb.202006159
Contributors: Fred D. Mast; Arti T. Navare; Almer M. van der Sloot; Jasmin Coulombe-Huntington; Michael P. Rout; Nitin S. Baliga; Alexis Kaushansky; Brian T. Chait; Alan Aderem; Charles M. Rice et al.
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Dengue activates mTORC2 signaling to counteract apoptosis and maximize viral replication

2020-09-22 | Preprint
DOI: 10.1101/2020.09.22.308890
Contributors: Christoph C. Carter; Jean Paul Olivier; Alexis Kaushansky; Fred D. Mast; John D. Aitchison
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A system-level gene regulatory network model forPlasmodium falciparum

2020-08-10 | Preprint
DOI: 10.1101/2020.08.10.235317
Contributors: ML Neal; L Wei; E Peterson; ML Arrieta-Ortiz; SA Danziger; NS Baliga; A Kaushansky; JD Aitchison
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Spatial presentation of biological molecules to cells by localized diffusive transfer

Lab on a Chip
2019 | Journal article
DOI: 10.1039/C9LC00122K
Contributors: Mary C. Regier; Emily Olszewski; Christoph C. Carter; John D. Aitchison; Alexis Kaushansky; Jennifer Davis; Erwin Berthier; David J. Beebe; Kelly R. Stevens
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Next Generation Histology-Directed Imaging Mass Spectrometry Driven by Autofluorescence Microscopy

Analytical Chemistry
2018-11-06 | Journal article
DOI: 10.1021/acs.analchem.8b02885
Contributors: Nathan Heath Patterson; Michael Tuck; Adam Lewis; Alexis Kaushansky; Jeremy L. Norris; Raf Van de Plas; Richard M. Caprioli
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A call to arms: Unifying the fight against resistance

Science Signaling
2018-10-23 | Journal article
DOI: 10.1126/scisignal.aav0442
Contributors: Alexis Kaushansky; Lizbeth Hedstrom; Aaron Goldman; Juswinder Singh; Priscilla L. Yang; Pradipsinh K. Rathod; Michael Cynamon; Dominik Wodarz; Daruka Mahadevan; Andrew Tomaras et al.
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Peer review (3 reviews for 3 publications/grants)

Review activity for ACS infectious diseases. (1)
Review activity for Cell death and differentiation. (1)
Review activity for Nature communications (1)
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