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Schlafen 11 further sensitizes BRCA-deficient cells to PARP inhibitors through single-strand DNA gap accumulation behind replication forks

Oncogene
2024-08-02 | Journal article
Contributors: Hiroshi Onji; Sota Tate; Tomohisa Sakaue; Kohei Fujiwara; Shiho Nakano; Miho Kawaida; Nobuyuki Onishi; Takashi Matsumoto; Wataru Yamagami; Takashi Sugiyama et al.
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Schlafen 11 further sensitizes BRCA-deficient cells to PARP inhibitors through single-strand DNA gap accumulation behind replication forks

2024-02-02 | Preprint
Contributors: Junko Murai; Hiroshi Onji; Sota Tate; Tomohisa Sakaue; Kohei Fujiwara; Miho Kawaida; Nobuyuki Onishi; Takashi Matsumoto; Wataru Yamagami; Takashi Sugiyama et al.
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Synergistic effects of PARP inhibitors by Schlafen 11 and BRCA2-deficiency through accumulation of single-strand DNA gaps behind a fork

2023-06-28 | Preprint
Contributors: Hiroshi Onji; Sota Tate; Tomohisa Sakaue; Nobuyuki Onishi; Takashi Matsumoto; Takashi Sugiyama; Shigeki Higashiyama; Junko Murai
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Reconsidering the mechanisms of action of PARP inhibitors based on clinical outcomes

Cancer Science
2022-09 | Journal article
Contributors: Hiroshi Onji; Junko Murai
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