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SciProfiles: 2858646
Scopus Author ID: 56596811100
Scopus Author ID: 56231322200

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Employment (1)

Universidade Federal do Rio Grande do Sul: Porto Alegre, Rio Grande do Sul, BR

2023-03-01 to present | PostDoc Position (Departamento de Bioquímica UFRGS)
Employment
Source: Self-asserted source
Ribeiro RT

Education and qualifications (3)

Universidade Federal do Rio Grande do Sul: Porto Alegre, RS, BR

2019-03-15 to 2023-02-16 | PhD (PPG Ciências Biológicas - Bioquímica)
Education
Source: Self-asserted source
Ribeiro RT

Universidade Federal do Rio Grande do Sul: Porto Alegre, RS, BR

2018-03 to 2019-03-11 | Master of Sciences (PPG Ciências Biológicas - Bioquímica)
Education
Source: Self-asserted source
Ribeiro RT

Universidade Federal do Rio Grande do Sul: Porto Alegre, RS, BR

2011-08 to 2018-07-02 | Pharmacist (Faculdade de Farmácia)
Education
Source: Self-asserted source
Ribeiro RT

Works (43)

Disturbances in mitochondrial quality control and mitochondria-lysosome contact underlie the cerebral cortex and heart damage of mucopolysaccharidosis type II mice

Metabolic Brain Disease
2025-04-12 | Journal article
DOI: 10.1007/s11011-025-01605-x
Contributors: Camila Vieira Pinheiro; Rafael Teixeira Ribeiro; Ana Cristina Roginski; Morgana Brondani; Ângela Beatris Zemniaçak; Chrístofer Ian Hernandez Hoffmann; Adriana Fernanda K. Vizuete; Carlos-Alberto Gonçalves; Alexandre Umpierrez Amaral; Moacir Wajner et al.
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Crossref

Maternal lactoferrin supplementation prevents mitochondrial and redox homeostasis dysfunction, and improves antioxidant defenses through Nrf2 and UCP2 signaling after neonatal hypoxia-ischemia

Free Radical Biology and Medicine
2025-02 | Journal article
DOI: 10.1016/j.freeradbiomed.2025.02.036
Part of ISSN: 0891-5849
Contributors: Andrey Vinicios S. Carvalho; Eduardo F. Sanches; Rafael T. Ribeiro; Luz Elena Durán-Carabali; Osmar Ramires Júnior; Bruna Dutra Muniz; Moacir Wajner; Angela T. Wyse; Carlos Alexandre Netto; Stéphane V. Sizonenko
Source: Self-asserted source
Ribeiro RT

α-Ketoisocaproic Acid Disrupts Mitochondrial Bioenergetics in the Brain of Neonate Rats: Molecular Modeling Studies of α-ketoglutarate Dehydrogenase Subunits Inhibition

Neurochemical Research
2025-02 | Journal article
DOI: 10.1007/s11064-024-04328-0
Contributors: Ângela Beatris Zemniaçak; Rafael Teixeira Ribeiro; Gustavo Machado das Neves; Sâmela de Azevedo Cunha; Tailine Quevedo Tavares; Andrey Vinícios Soares Carvalho; Carlos Alexandre Netto; Roger Frigério Castilho; Moacir Wajner; Alexandre Umpierrez Amaral
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Protective effects of the PPAR agonist bezafibrate against disruption of redox and energy homeostasis, neuronal death, astroglial reactivity, and neuroinflammation induced in vivo by D-2-hydroxyglutaric acid in rat brain

European Journal of Pharmacology
2025-01 | Journal article
DOI: 10.1016/j.ejphar.2024.177186
Contributors: Rafael Teixeira Ribeiro; Manuela Bianchin Marcuzzo; Andrey Vinícios Soares Carvalho; Rafael Palavro; Ediandra Tissot Castro; Camila Vieira Pinheiro; Larissa Daniele Bobermin; Alexandre Umpierrez Amaral; Guilhian Leipnitz; Carlos Alexandre Netto et al.
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Crossref

L-carnitine protects against oxidative damage and neuroinflammation in cerebral cortex of rats submitted to chronic chemically-induced model of hyperphenylalaninemia

Metabolic Brain Disease
2025-01-18 | Journal article
DOI: 10.1007/s11011-025-01537-6
Part of ISSN: 1573-7365
Contributors: Jéssica Lamberty Faverzani; Gilian Guerreiro; Franciele Fatima Lopes; Angela Sitta; Daniella de Moura Coelho; Caroline Paula Mescka; Luísa Degrandi Sehn; Gabriel de Lima Rosa; Amanda Muliterno Domingues Lourenço de Lima; Esteban Alberto Gonzalez et al.
Source: Self-asserted source
Ribeiro RT

Impairment of neuromotor development and cognition associated with histopathological and neurochemical abnormalities in the cerebral cortex and striatum of glutaryl-CoA dehydrogenase deficient mice

Neurochemistry International
2024-12 | Journal article
DOI: 10.1016/j.neuint.2024.105898
Part of ISSN: 0197-0186
Contributors: Ediandra Tissot Castro; Rafael Teixeira Ribeiro; Andrey Vinicios Soares Carvalho; Diorlon Nunes Machado; Ângela Beatris Zemniaçak; Rafael Palavro; Sâmela de Azevedo Cunha; Tailine Quevedo Tavares; Diogo Onofre Gomes de Souza; Carlos Alexandre Netto et al.
Source: Self-asserted source
Ribeiro RT

Oxidative Stress Associated With Increased Reactive Nitrogen Species Generation in the Liver and Kidney Caused by a Major Metabolite Accumulating in Tyrosinemia Type 1

Cell Biochemistry and Function
2024-12 | Journal article
DOI: 10.1002/cbf.70010
Contributors: Julia Gabrieli Bender; Rafael Teixeira Ribeiro; Ângela Beatris Zemniaçak; Rafael Palavro; Rafael Aguiar Marschner; Simone Magagnin Wajner; Ediandra Tissot Castro; Guilhian Leipnitz; Moacir Wajner; Alexandre Umpierrez Amaral
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Crossref

3-Hydroxy-3-Methylglutaric Acid Disrupts Brain Bioenergetics, Redox Homeostasis, and Mitochondrial Dynamics and Affects Neurodevelopment in Neonatal Wistar Rats

Biomedicines
2024-07-15 | Journal article
DOI: 10.3390/biomedicines12071563
Contributors: Josyane de Andrade Silveira; Manuela Bianchin Marcuzzo; Jaqueline Santana da Rosa; Nathalia Simon Kist; Chrístofer Ian Hernandez Hoffmann; Andrey Soares Carvalho; Rafael Teixeira Ribeiro; André Quincozes-Santos; Carlos Alexandre Netto; Moacir Wajner et al.
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In Vivo Intracerebral Administration of α-Ketoisocaproic Acid to Neonate Rats Disrupts Brain Redox Homeostasis and Promotes Neuronal Death, Glial Reactivity, and Myelination Injury

Molecular Neurobiology
2024-05 | Journal article
DOI: 10.1007/s12035-023-03718-9
Contributors: Ângela Beatris Zemniaçak; Rafael Teixeira Ribeiro; Camila Vieira Pinheiro; Sâmela de Azevedo Cunha; Tailine Quevedo Tavares; Ediandra Tissot Castro; Guilhian Leipnitz; Moacir Wajner; Alexandre Umpierrez Amaral
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Type 3 Deiodinase is Induced in Brain Of Two Models Leading to Cognitive Impairment

2024-04-10 | Preprint
DOI: 10.21203/rs.3.rs-4222656/v1
Contributors: Milla Paim Dreher; Thaliane Carvalho Oliveira; Jessica Carvalho Sindô¹; Maria Inês Gonzalez Solari¹; Rafael Teixeira Ribeiro; Larisse Longo; Vitor Gayger-Dias; Vanessa-Fernanda Silva; Laura Bayni Rodrigues Freitas; Carlos-Alberto Gonçalves et al.
Source: Self-asserted source
Ribeiro RT

Disturbances in mitochondrial bioenergetics and control quality and unbalanced redox homeostasis in the liver of a mouse model of mucopolysaccharidosis type II

Molecular and Cellular Biochemistry
2024-03-18 | Journal article
DOI: 10.1007/s11010-024-04952-y
Part of ISSN: 0300-8177
Part of ISSN: 1573-4919
Contributors: Camila Vieira Pinheiro; Rafael Teixeira Ribeiro; Ana Cristina Roginski; Morgana Brondani; Ângela Beatris Zemniaçak; Chrístofer Ian Hernandez Hoffmann; Alexandre Umpierrez Amaral; Moacir Wajner; Guilherme Baldo; Guilhian Leipnitz
Source: Self-asserted source
Ribeiro RT
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N-Acetylglutamate and N-acetylmethionine compromise mitochondrial bioenergetics homeostasis and glutamate oxidation in brain of developing rats: Potential implications for the pathogenesis of ACY1 deficiency

Biochemical and Biophysical Research Communications
2023-12 | Journal article
DOI: 10.1016/j.bbrc.2023.149123
Contributors: Vanessa Trindade Bortoluzzi; Rafael Teixeira Ribeiro; Camila Vieira Pinheiro; Ediandra Tissot Castro; Tailine Quevedo Tavares; Guilhian Leipnitz; Jörn Oliver Sass; Roger Frigério Castilho; Alexandre Umpierrez Amaral; Moacir Wajner
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Disturbance of mitochondrial functions caused by N-acetylglutamate and N-acetylmethionine in brain of adolescent rats: Potential relevance in aminoacylase 1 deficiency

Neurochemistry International
2023-10 | Journal article | Author
DOI: 10.1016/j.neuint.2023.105631
Part of ISSN: 0197-0186
Contributors: Bortoluzzi, V. T.; Ribeiro RT; Ângela Zemniaçak; Sâmela de Azevedo Cunha; Jörn Oliver Sass; Roger Frigério Castilho; Amaral AU; Moacir Wajner
Source: Self-asserted source
Ribeiro RT
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Inflammation and Redox Homeostasis Induces Type 3 Deiodinase and Impacts Brain Endoplasmic Reticulum–Mitochondria Crosstalk Both in Local and Systemic Disease Models

2023-10-03 | Preprint
DOI: 10.21203/rs.3.rs-3304213/v1
Contributors: Rafael Aguiar Marschner; Thaliane Carvalho Oliveira; Milla Paim Dreher; Julia Maria Correa; Rafael Teixeira Ribeiro; Vitor Gayger Dias; Vanessa Fernanda Silva; Laura Freitas; Carlos Alberto Gonçalves; Mario Reis Alvares-da-Silva et al.
Source: Self-asserted source
Ribeiro RT

Glycine disrupts myelin, glutamatergic neurotransmission, and redox homeostasis in a neonatal model for non ketotic hyperglycinemia

Biochimie
2023-08 | Journal article
DOI: 10.1016/j.biochi.2023.07.022
Part of ISSN: 0300-9084
Contributors: Belisa Parmeggiani; Marian Flores Signori; Cristiane Cecatto; Marina Rocha Frusciante; Manuela Bianchin Marcuzzo; Débora Guerini Souza; Rafael Teixeira Ribeiro; Bianca Seminotti; Diogo Onofre Gomes de Souza; César Augusto João Ribeiro et al.
Source: Self-asserted source
Ribeiro RT

Sulfite Impairs Bioenergetics and Redox Status in Neonatal Rat Brain: Insights into the Early Neuropathophysiology of Isolated Sulfite Oxidase and Molybdenum Cofactor Deficiencies

Cellular and Molecular Neurobiology
2023-08 | Journal article
DOI: 10.1007/s10571-023-01328-6
Contributors: Júlia Pramio; Mateus Grings; Amanda Gasparin da Rosa; Rafael Teixeira Ribeiro; Nícolas Manzke Glanzel; Marian Flores Signori; Manuela Bianchin Marcuzzo; Larissa Daniele Bobermin; Angela T. S. Wyse; André Quincozes-Santos et al.
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Mitochondrial dysfunction, oxidative stress, ER stress and mitochondria-ER crosstalk alterations in a chemical rat model of Huntington's disease: Potential benefits of bezafibrate

Toxicology Letters
2023-05 | Journal article
DOI: 10.1016/j.toxlet.2023.04.011
Part of ISSN: 0378-4274
Contributors: Morgana Brondani; Ana Cristina Roginski; Rafael Teixeira Ribeiro; Maria Paula de Medeiros; Chrístofer Ian Hernandez Hoffmann; Moacir Wajner; Guilhian Leipnitz; Bianca Seminotti
Source: Self-asserted source
Ribeiro RT

Disruption of mitochondrial bioenergetics and calcium homeostasis by phytanic acid in the heart: Potential relevance for the cardiomyopathy in Refsum disease

Biochimica et Biophysica Acta (BBA) - Bioenergetics
2023-04 | Journal article
DOI: 10.1016/j.bbabio.2023.148961
Part of ISSN: 0005-2728
Contributors: Ângela Beatriz Zemniaçak; Ana Cristina Roginski; Rafael Teixeira Ribeiro; Julia Gabrieli Bender; Rafael Aguiar Marschner; Simone Magagnin Wajner; Moacir Wajner; Alexandre Umpierrez Amaral
Source: Self-asserted source
Ribeiro RT

l-2-Hydroxyglutaric Acid Administration to Neonatal Rats Elicits Marked Neurochemical Alterations and Long-Term Neurobehavioral Disabilities Mediated by Oxidative Stress

Neurotoxicity Research
2023-04 | Journal article
DOI: 10.1007/s12640-022-00625-0
Contributors: Rafael Teixeira Ribeiro; Andrey Vinícios Soares Carvalho; Rafael Palavro; Luz Elena Durán-Carabali; Ângela Beatris Zemniaçak; Alexandre Umpierrez Amaral; Carlos Alexandre Netto; Moacir Wajner
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Crossref

Uncovering Actions of Type 3 Deiodinase in the Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD)

Cells
2023-03-27 | Journal article
DOI: 10.3390/cells12071022
Contributors: Rafael Aguiar Marschner; Ana Cristina Roginski; Rafael Teixeira Ribeiro; Larisse Longo; Mário Reis Álvares-da-Silva; Simone Magagnin Wajner
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Understanding the Progression of Metabolic Dysfunction Asso-Ciated Fatty Liver Disease (MAFLD): Early Effect on Mitochon-Dria and Krebs Cycle Due to Type 3 Deiodinase Dysfunction

2022-12-06 | Preprint
DOI: 10.20944/preprints202212.0091.v1
Contributors: Rafael Aguiar Marschner; Ana Cristina Roginski; Rafael Teixeira Ribeiro; Larisse Longo; Laura Bainy Rodrigues de Freitas; Mario Reis Álvares-da-Silva; Simone Wajner
Source: Self-asserted source
Ribeiro RT

Disruption of mitochondrial bioenergetics, calcium retention capacity and cell viability caused by D-2-hydroxyglutaric acid in the heart

Biochimie
2022-11 | Journal article
DOI: 10.1016/j.biochi.2022.11.004
Part of ISSN: 0300-9084
Contributors: Rafael Teixeira Ribeiro; Ana Cristina Roginski; Rafael Aguiar Marschner; Simone Magagnin Wajner; Roger Frigério Castilho; Alexandre Umpierrez Amaral; Moacir Wajner
Source: Self-asserted source
Ribeiro RT

Disruption of mitochondrial functions involving mitochondrial permeability transition pore opening caused by maleic acid in rat kidney

Journal of Bioenergetics and Biomembranes
2022-08 | Journal article
DOI: 10.1007/s10863-022-09945-4
Part of ISSN: 0145-479X
Part of ISSN: 1573-6881
Contributors: Ana Cristina Roginski; Ângela Beatris Zemniaçak; Rafael Aguiar Marschner; Simone Magagnin Wajner; Rafael Teixeira Ribeiro; Moacir Wajner; Alexandre Umpierrez Amaral
Source: Self-asserted source
Ribeiro RT

Disturbance of Mitochondrial Dynamics, Endoplasmic Reticulum–Mitochondria Crosstalk, Redox Homeostasis, and Inflammatory Response in the Brain of Glutaryl-CoA Dehydrogenase-Deficient Mice: Neuroprotective Effects of Bezafibrate

Molecular Neurobiology
2022-08 | Journal article
DOI: 10.1007/s12035-022-02887-3
Contributors: Bianca Seminotti; Morgana Brondani; Rafael Teixeira Ribeiro; Guilhian Leipnitz; Moacir Wajner
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Crossref

Influence of Altered Thyroid Hormone Mechanisms in the Progression of Metabolic Dysfunction Associated with Fatty Liver Disease (MAFLD): A Systematic Review

Metabolites
2022-07-22 | Journal article
DOI: 10.3390/metabo12080675
Contributors: Rafael Aguiar Marschner; Fernanda Arenhardt; Rafael Teixeira Ribeiro; Simone Magagnin Wajner
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Crossref
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Plinia trunciflora Extract Administration Prevents HI-Induced Oxidative Stress, Inflammatory Response, Behavioral Impairments, and Tissue Damage in Rats.

Nutrients
2022-01-17 | Journal article
DOI: 10.3390/nu14020395
PMID: 35057576
PMC: PMC8779767
Source: Self-asserted source
Ribeiro RT

S-adenosylmethionine induces mitochondrial dysfunction, permeability transition pore opening and redox imbalance in subcellular preparations of rat liver

Journal of Bioenergetics and Biomembranes
2021-10 | Journal article
DOI: 10.1007/s10863-021-09914-3
Source: Self-asserted source
Ribeiro RT
grade
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Neuronal Death, Glial Reactivity, Microglia Activation, Oxidative Stress and Bioenergetics Impairment Caused by Intracerebroventricular Administration of D-2-hydroxyglutaric Acid to Neonatal Rats.

Neuroscience
2021-07-30 | Journal article
DOI: 10.1016/j.neuroscience.2021.07.024
PMID: 34333063
Source: Self-asserted source
Ribeiro RT

Differential Age-Dependent Mitochondrial Dysfunction, Oxidative Stress, and Apoptosis Induced by Neonatal Hypoxia-Ischemia in the Immature Rat Brain.

Molecular neurobiology
2021-01-08 | Journal article
DOI: 10.1007/s12035-020-02261-1
PMID: 33417220
Source: Self-asserted source
Ribeiro RT

3-Hydroxy-3-Methylglutaric Acid Impairs Redox and Energy Homeostasis, Mitochondrial Dynamics, and Endoplasmic Reticulum-Mitochondria Crosstalk in Rat Brain.

Neurotoxicity research
2019-11-13 | Journal article
DOI: 10.1007/s12640-019-00122-x
PMID: 31721046
Source: Self-asserted source
Ribeiro RT

Free Radical Scavengers Prevent Argininosuccinic Acid-Induced Oxidative Stress in the Brain of Developing Rats: a New Adjuvant Therapy for Argininosuccinate Lyase Deficiency?

Molecular neurobiology
2019-11-09 | Journal article
DOI: 10.1007/s12035-019-01825-0
PMID: 31707633
Source: Self-asserted source
Ribeiro RT

Acute lysine overload provokes marked striatum injury involving oxidative stress signaling pathways in glutaryl-CoA dehydrogenase deficient mice

Neurochemistry International
2019-10 | Journal article
DOI: 10.1016/j.neuint.2019.104467
Part of ISSN: 0197-0186
Source: Self-asserted source
Ribeiro RT

l-Carnitine prevents oxidative stress in striatum of glutaryl-CoA dehydrogenase deficient mice submitted to lysine overload

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
2019-09 | Journal article
DOI: 10.1016/j.bbadis.2019.06.007
Part of ISSN: 0925-4439
Source: Self-asserted source
Ribeiro RT
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Disruption of Brain Redox Homeostasis, Microglia Activation and Neuronal Damage Induced by Intracerebroventricular Administration of S-Adenosylmethionine to Developing Rats

Molecular Neurobiology
2019-04 | Journal article
DOI: 10.1007/s12035-018-1275-6
Part of ISSN: 0893-7648
Part of ISSN: 1559-1182
Source: Self-asserted source
Ribeiro RT

S-Adenosylmethionine Promotes Oxidative Stress and Decreases Na+, K+-ATPase Activity in Cerebral Cortex Supernatants of Adolescent Rats: Implications for the Pathogenesis of S-Adenosylhomocysteine Hydrolase Deficiency

Molecular Neurobiology
2018-07 | Journal article
DOI: 10.1007/s12035-017-0804-z
Part of ISSN: 0893-7648
Part of ISSN: 1559-1182
Source: Self-asserted source
Ribeiro RT

Experimental Evidence that In Vivo Intracerebral Administration of L-2-Hydroxyglutaric Acid to Neonatal Rats Provokes Disruption of Redox Status and Histopathological Abnormalities in the Brain

Neurotoxicity Research
2018-04 | Journal article
DOI: 10.1007/s12640-018-9874-6
Part of ISSN: 1029-8428
Part of ISSN: 1476-3524
Source: Self-asserted source
Ribeiro RT

Induction of Neuroinflammatory Response and Histopathological Alterations Caused by Quinolinic Acid Administration in the Striatum of Glutaryl-CoA Dehydrogenase Deficient Mice

Neurotoxicity Research
2018-04 | Journal article
DOI: 10.1007/s12640-017-9848-0
Part of ISSN: 1029-8428
Part of ISSN: 1476-3524
Source: Self-asserted source
Ribeiro RT
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Mevalonolactone disrupts mitochondrial functions and induces permeability transition pore opening in rat brain mitochondria: Implications for the pathogenesis of mevalonic aciduria

Neurochemistry International
2017-09 | Journal article
DOI: 10.1016/j.neuint.2017.03.005
Part of ISSN: 0197-0186
Source: Self-asserted source
Ribeiro RT

α-Ketoadipic Acid and α-Aminoadipic Acid Cause Disturbance of Glutamatergic Neurotransmission and Induction of Oxidative Stress In Vitro in Brain of Adolescent Rats

Neurotoxicity Research
2017-08 | Journal article
DOI: 10.1007/s12640-017-9735-8
Part of ISSN: 1029-8428
Part of ISSN: 1476-3524
Source: Self-asserted source
Ribeiro RT

Oxidative Stress, Disrupted Energy Metabolism, and Altered Signaling Pathways in Glutaryl-CoA Dehydrogenase Knockout Mice: Potential Implications of Quinolinic Acid Toxicity in the Neuropathology of Glutaric Acidemia Type I

Molecular Neurobiology
2016-11 | Journal article
DOI: 10.1007/s12035-015-9548-9
Part of ISSN: 0893-7648
Part of ISSN: 1559-1182
Source: Self-asserted source
Ribeiro RT
grade
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cis-4-Decenoic and decanoic acids impair mitochondrial energy, redox and Ca 2+ homeostasis and induce mitochondrial permeability transition pore opening in rat brain and liver: Possible implications for the pathogenesis of MCAD deficiency

Biochimica et Biophysica Acta (BBA) - Bioenergetics
2016-09 | Journal article
DOI: 10.1016/j.bbabio.2016.05.007
Part of ISSN: 0005-2728
Source: Self-asserted source
Ribeiro RT

In vivo intracerebral administration of L-2-hydroxyglutaric acid provokes oxidative stress and histopathological alterations in striatum and cerebellum of adolescent rats

Free Radical Biology and Medicine
2015-06 | Journal article
DOI: 10.1016/j.freeradbiomed.2015.02.008
Part of ISSN: 0891-5849
Source: Self-asserted source
Ribeiro RT
grade
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Acute lysine overload provokes protein oxidative damage and reduction of antioxidant defenses in the brain of infant glutaryl-CoA dehydrogenase deficient mice: A role for oxidative stress in GA I neuropathology

Journal of the Neurological Sciences
2014-09 | Journal article
DOI: 10.1016/j.jns.2014.06.034
Part of ISSN: 0022-510X
Source: Self-asserted source
Ribeiro RT
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