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Employment (2)

University of California San Diego Health Sciences: La Jolla, CA, US

2022-07 to present | Assistant Project Scientist (Moores Cancer Center)
Employment
Source: Self-asserted source
Yun Huang

University Children's Hospital Zurich: Zurich, CH

2013-01 to 2022-06 | Research fellow (Division of Oncology)
Employment
Source: Self-asserted source
Yun Huang

Education and qualifications (2)

University of Science and Technology of China: Hefei, CN

2006-09-01 to 2012-04-04 | PhD
Education
Source: Self-asserted source
Yun Huang

Anhui University: Hefei, Anhui, CN

2002-09 to 2006-06 | Bachelor of Science (Life Science School)
Education
Source: Self-asserted source
Yun Huang

Funding (4)

Deciphering enhancer reprograming functions of the oncogenic TCF3-HLF fusion in leukemia

Grant
Krebsliga Schweiz (Zurich, CH)
Source: Self-asserted source
Yun Huang

Enhancer factor EP300/CREBBP and metabolic dependencies in high-risk acute lymphoblastic leukemia

Grant
Krebsliga Schweiz (Zurich, CH)
Source: Self-asserted source
Yun Huang

Functional identification of specific dependencies in high-risk leukemia to develop new treatments

Grant
Swiss Life - Jubiläumsstiftung (Zurich, CH)
Source: Self-asserted source
Yun Huang

Modeling and targeting critical oncogenic determinants driven by the TCF3-HLF translocation in high risk ALL

Grant
Krebsliga Schweiz (Zurich, CH)
Source: Self-asserted source
Yun Huang

Works (18)

Rapid Generation of Leukemogenic Chromosomal Translocations in Vivo Using CRISPR/Cas9

HemaSphere
2020 | Journal article
Source: Self-asserted source
Yun Huang

Targeting the oncogenic activity of TCF3-HLF in leukemia

Molecular & Cellular Oncology
2020 | Journal article
Source: Self-asserted source
Yun Huang

$γ$-Catenin-Dependent Signals Maintain BCR-ABL1+ B Cell Acute Lymphoblastic Leukemia

Cancer cell
2019 | Journal article
Source: Self-asserted source
Yun Huang

The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability

Cancer cell
2019 | Journal article
Source: Self-asserted source
Yun Huang

Chromosome nondisjunction during bipolar mitoses of binucleated intermediates promote aneuploidy formation along with multipolar mitoses rather than chromosome loss in micronuclei induced by asbestos

Oncotarget
2017 | Journal article
Source: Self-asserted source
Yun Huang

Efficient generation of multi-gene knockout cell lines and patient-derived xenografts using multi-colored lenti-CRISPR-Cas9

Bio-protocol
2017 | Journal article
Source: Self-asserted source
Yun Huang

Image-based RNA interference screening reveals an individual dependence of acute lymphoblastic leukemia on stromal cysteine support

Oncotarget
2014 | Journal article
Source: Self-asserted source
Yun Huang

Unrepaired DNA damage facilitates elimination of uniparental chromosomes in interspecific hybrid cells

Cell Cycle
2014 | Journal article
Source: Self-asserted source
Yun Huang

Inhibitors of phosphatidylinositol 3′-kinases promote mitotic cell death in HeLa cells

PloS one
2012 | Journal article
Source: Self-asserted source
Yun Huang

Lagging chromosomes entrapped in micronuclei are not'lost'by cells

Cell research
2012 | Journal article
Source: Self-asserted source
Yun Huang

Rapid proliferation of daughter cells lacking particular chromosomes due to multipolar mitosis promotes clonal evolution in colorectal cancer cells

Cell Cycle
2012 | Journal article
Source: Self-asserted source
Yun Huang

Regulation of asymmetrical cytokinesis by cAMP during meiosis I in mouse oocytes

PloS one
2012 | Journal article
Source: Self-asserted source
Yun Huang

Tetraploid cells from cytokinesis failure induce aneuploidy and spontaneous transformation of mouse ovarian surface epithelial cells

Cell cycle
2012 | Journal article
Source: Self-asserted source
Yun Huang

Micronucleus formation detected by live-cell imaging

Mutagenesis
2011 | Journal article
Source: Self-asserted source
Yun Huang

p53 dependent centrosome clustering prevents multipolar mitosis in tetraploid cells

PLoS One
2011 | Journal article
Source: Self-asserted source
Yun Huang

The fate of micronucleated cells post X-irradiation detected by live cell imaging

DNA repair
2011 | Journal article
Source: Self-asserted source
Yun Huang

Nucleophosmin/B23 inhibits Eg5-mediated microtubule depolymerization by inactivating its ATPase activity

Journal of Biological Chemistry
2010 | Journal article
Source: Self-asserted source
Yun Huang

Multiple origins of spontaneously arising micronuclei in HeLa cells: direct evidence from long-term live cell imaging

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
2008 | Journal article
Source: Self-asserted source
Yun Huang

Peer review (17 reviews for 5 publications/grants)

Review activity for Biomarker research. (2)
Review activity for Cancer cell international. (9)
Review activity for Cellular oncology. (1)
Review activity for Journal of experimental & clinical cancer research. (2)
Review activity for Journal of translational medicine. (3)
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