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Loop profile: 479524

Keywords

Immunology, Diabetes, Molecular Biology

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United States

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Employment (3)

Allegheny General Hospital: Pittsburgh, PA, US

2016-08 to present | Senior Scientist (ICT)
Employment
Source: Self-asserted source
Brett Phillips

Pennsylvania State University College of Medicine: Hershey, PA, US

2011-08 to 2016-06 | Research Assistant (Surgery)
Employment
Source: Self-asserted source
Brett Phillips

University of Pittsburgh: Pittsburgh, PA, US

2007-06 to 2011-06 | Post-Doctoral Scholar (Immunogenetics)
Employment
Source: Self-asserted source
Brett Phillips

Education and qualifications (2)

Pennsylvania State University College of Medicine: Hershey, PA, US

2001-09 to 2007-03 | PhD Cellular and Molecular Physiology (Physiology)
Education
Source: Self-asserted source
Brett Phillips

Millersville University Department of Biology: Millersville, PA, US

1997-09 to 2001-06 | BS Molecular Biology
Education
Source: Self-asserted source
Brett Phillips

Works (41)

Improvement in insulin sensitivity and prevention of high fat diet-induced liver pathology using a CXCR2 antagonist.

Cardiovascular diabetology
2022-07-12 | Journal article
DOI: 10.1186/s12933-022-01564-y
PMID: 35831885
PMC: PMC9277870
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Mechanobiology of the Intervertebral Disc and Treatments Working in Conjunction with the Human Anatomy

Handbook of Spine Technology
2021 | Book chapter
DOI: 10.1007/978-3-319-33037-2_22-1
Part of ISBN: 9783319330372
Part of ISBN: 9783319330372
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Neutrophils and their role in the aetiopathogenesis of type 1 and type 2 diabetes.

Diabetes/metabolism research and reviews
2021-07-18 | Review
DOI: 10.1002/dmrr.3483
PMID: 34245096
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Human Hemangioblast-Derived Mesenchymal Stem Cells Promote Islet Engraftment in a Minimal Islet Mass Transplantation Model in Mice.

Frontiers in medicine
2021-04-15 | Journal article
DOI: 10.3389/fmed.2021.660877
PMID: 33937296
PMC: PMC8081894
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Neutrophil-Associated Inflammatory Changes in the Pre-Diabetic Pancreas of Early-Age NOD Mice.

Frontiers in endocrinology
2021-03-10 | Journal article
DOI: 10.3389/fendo.2021.565981
PMID: 33776903
PMC: PMC7988208
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Arrest in the Progression of Type 1 Diabetes at the Mid-Stage of Insulitic Autoimmunity Using an Autoantigen-Decorated All-<i>trans</i> Retinoic Acid and Transforming Growth Factor Beta-1 Single Microparticle Formulation.

Frontiers in immunology
2021-03-08 | Journal article
DOI: 10.3389/fimmu.2021.586220
PMID: 33763059
PMC: PMC7982719
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Significant lipid and neutrophil accumulation and active inflammasome in high BMI tumor regions of human pancreatic ductal adenocarcinoma.

Journal of Clinical Oncology
2021-01-20 | Conference abstract
DOI: 10.1200/jco.2021.39.3_suppl.438
Part of ISSN: 0732-183X
Part of ISSN: 1527-7755
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

The Role of Genetic Variant rs13266634 in SLC30A8/ZnT8 in Postoperative Hyperglycemia After Major Abdominal Surgery

The Journal of Clinical Endocrinology & Metabolism
2019-09-01 | Journal article
DOI: 10.1210/jc.2018-02588
Part of ISSN: 0021-972X
Part of ISSN: 1945-7197
Source: Self-asserted source
Brett Phillips

Significant neutrophil accumulation, IL-18 deposition, and active inflammasome in tumor regions of human pancreatic ductal adenocarcinoma.

Journal of Clinical Oncology
2019-05-20 | Conference abstract
DOI: 10.1200/jco.2019.37.15_suppl.e15754
Part of ISSN: 0732-183X
Part of ISSN: 1527-7755
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Tolerogenic Dendritic Cells and T-Regulatory Cells at the Clinical Trials Crossroad for the Treatment of Autoimmune Disease; Emphasis on Type 1 Diabetes Therapy

Frontiers in Immunology
2019-02-06 | Review
DOI: 10.3389/fimmu.2019.00148
Part of ISSN: 1664-3224
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

The Sex-specific Effects of LPS on Depressive-like Behavior and Oxidative Stress in the Hippocampus of the Mouse.

Neuroscience
2018-12-14 | Journal article
DOI: 10.1016/j.neuroscience.2018.12.008
PMID: 30553795
Source: Self-asserted source
Brett Phillips

Co-Stimulation-Impaired Bone Marrow-Derived Dendritic Cells Prevent Dextran Sodium Sulfate-Induced Colitis in Mice

Frontiers in Immunology
2018-05-03 | Journal article
DOI: 10.3389/fimmu.2018.00894
Part of ISSN: 1664-3224
Source: Self-asserted source
Brett Phillips

Salivary cotinine levels in children with otolaryngological disorders

International Journal of Pediatric Otorhinolaryngology
2017-11 | Journal article
DOI: 10.1016/j.ijporl.2017.08.023
Contributors: Christine M. Clark; Jillian N. Printz; Lauren E. Stahl; Brett E. Phillips; Michele M. Carr
Source: check_circle
Crossref

Immune and metabolic responses in early and late sepsis during mild dietary zinc restriction

Journal of Surgical Research
2017-04 | Journal article
DOI: 10.1016/j.jss.2016.10.020
Part of ISSN: 0022-4804
Source: Self-asserted source
Brett Phillips
grade
Preferred source (of 2)‎

Oral omega-3 fatty acids promote resolution in chemical peritonitis

Journal of Surgical Research
2016-11 | Journal article
DOI: 10.1016/j.jss.2016.06.036
Part of ISSN: 0022-4804
Source: Self-asserted source
Brett Phillips

Sarcopenia and sarcopenic obesity in patients with complex abdominal wall hernias

The American Journal of Surgery
2016-11 | Journal article
DOI: 10.1016/j.amjsurg.2016.03.003
Part of ISSN: 0002-9610
Source: Self-asserted source
Brett Phillips

Impaired recovery from peritoneal inflammation in a mouse model of mild dietary zinc restriction.

Molecular nutrition & food research
2016-02-02 | Journal article
DOI: 10.1002/mnfr.201500688
PMID: 26627196
Source: Self-asserted source
Brett Phillips

Absence of the zinc transporter ZnT2 in the intestinal Paneth cell increases susceptibility of mucosal crypt cells to microbial stress

Journal of the American College of Surgeons
2015-10 | Conference poster
DOI: 10.1016/j.jamcollsurg.2015.08.195
Part of ISSN: 1072-7515
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Mild Systemic Zinc Imbalance Delays Recovery in a Mouse Model of Surgically-Induced Ileus: Is it Driven by Disturbances in the Cytokine Network or Pro-Inflammatory Components of the Lipidome?

Journal of the American College of Surgeons
2014-09 | Conference abstract
DOI: 10.1016/j.jamcollsurg.2014.07.089
Part of ISSN: 1072-7515
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Peri-procedural povidone-iodine rectal preparation reduces microorganism counts and infectious complications following ultrasound-guided needle biopsy of the prostate

World Journal of Urology
2014-08 | Journal article
DOI: 10.1007/s00345-014-1291-8
Part of ISSN: 0724-4983
Part of ISSN: 1433-8726
Source: Self-asserted source
Brett Phillips

Involvement of Suppressive B-Lymphocytes in the Mechanism of Tolerogenic Dendritic Cell Reversal of Type 1 Diabetes in NOD Mice

PLoS ONE
2014-01-17 | Journal article
DOI: 10.1371/journal.pone.0083575
Part of ISSN: 1932-6203
Source: Self-asserted source
Brett Phillips

Prevalence of systemic inflammation and micronutrient imbalance in patients with complex abdominal hernias.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
2013-12-20 | Journal article
DOI: 10.1007/s11605-013-2431-y
PMID: 24356980
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Round window membrane permeability to golimumab in guinea pigs: a pilot study.

The Laryngoscope
2013-06-25 | Journal article
DOI: 10.1002/lary.24163
PMID: 23801274
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Type 1 Diabetes Immunotherapy - Successes, Failures and Promises

Type 1 Diabetes - Pathogenesis, Genetics and Immunotherapy
2011-11-25 | Book chapter
DOI: 10.5772/22062
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

FoxO6 integrates insulin signaling with gluconeogenesis in the liver.

Diabetes
2011-09-22 | Journal article
DOI: 10.2337/db11-0548
PMID: 21940782
PMC: PMC3198083
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Phosphatidylinositol-3-kinase activity during in vitro dendritic cell generation determines suppressive or stimulatory capacity.

Immunologic research
2011-08-01 | Journal article
DOI: 10.1007/s12026-011-8206-1
PMID: 21476100
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Current state of type 1 diabetes immunotherapy: incremental advances, huge leaps, or more of the same?

Clinical & developmental immunology
2011-07-18 | Review
DOI: 10.1155/2011/432016
PMID: 21785616
PMC: PMC3139873
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Phase I (safety) study of autologous tolerogenic dendritic cells in type 1 diabetic patients.

Diabetes care
2011-06-16 | Journal article
DOI: 10.2337/dc11-0472
PMID: 21680720
PMC: PMC3161299
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Interleukin-7 matures suppressive CD127(+) forkhead box P3 (FoxP3)(+) T cells into CD127(-) CD25(high) FoxP3(+) regulatory T cells.

Clinical and experimental immunology
2011-03-17 | Journal article
DOI: 10.1111/j.1365-2249.2011.04334.x
PMID: 21413939
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Drug delivery technologies for autoimmune disease.

Expert opinion on drug delivery
2010-10-20 | Review
DOI: 10.1517/17425247.2010.527329
PMID: 20958218
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

A peptide-based material platform for displaying antibodies to engage T cells.

Biomaterials
2010-09-28 | Journal article
DOI: 10.1016/j.biomaterials.2010.08.083
PMID: 20880580
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Identification of a cardiac specific protein transduction domain by in vivo biopanning using a M13 phage peptide display library in mice.

PloS one
2010-08-17 | Journal article
DOI: 10.1371/journal.pone.0012252
PMID: 20808875
PMC: PMC2923200
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Autoimmune diseases: symptoms, diagnosis, and treatment

Nova Biomedical/Nova Science Publishers
2010-03-12 | Book chapter
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Dendritic cell-based therapy in Type 1 diabetes mellitus.

Expert review of clinical immunology
2009-05-01 | Journal article
DOI: 10.1586/eci.09.8
PMID: 20477010
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Dendritic cell mediated therapy for immunoregulation of type 1 diabetes mellitus.

Pediatric endocrinology reviews : PER
2008-06-01 | Review
PMID: 18552749
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Toward a cure for type 1 diabetes mellitus: diabetes-suppressive dendritic cells and beyond.

Pediatric diabetes
2008-06-01 | Review
DOI: 10.1111/j.1399-5448.2008.00401.x
PMID: 18540865
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

A microsphere-based vaccine prevents and reverses new-onset autoimmune diabetes.

Diabetes
2008-03-03 | Journal article
DOI: 10.2337/db07-0507
PMID: 18316361
PMC: PMC2713034
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Occludin independently regulates permeability under hydrostatic pressure and cell division in retinal pigment epithelial cells.

Investigative ophthalmology & visual science
2008-02-08 | Journal article
DOI: 10.1167/iovs.07-1204
PMID: 18263810
PMC: PMC2483238
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Glucocorticoids induce transactivation of tight junction genes occludin and claudin-5 in retinal endothelial cells via a novel cis-element.

Experimental eye research
2008-01-12 | Journal article
DOI: 10.1016/j.exer.2008.01.002
PMID: 18501346
PMC: PMC2613867
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Renal diseases as targets of gene therapy.

Contributions to nephrology
2008-01-01 | Review
DOI: 10.1159/000125552
PMID: 18391581
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips

Blood Retinal Barrier

Retinal Vascular Disease
Book chapter
DOI: 10.1007/978-3-540-29542-6_8
Part of ISBN: 9783540295419
Contributors: Brett Phillips
Source: Self-asserted source
Brett Phillips
How many people are using ORCID?