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Scopus Author ID: 7103388892
ResearcherID: Q-1205-2017
SciProfiles: 164872

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Employment (1)

University of Maryland, IBBR: Rockville, MD, US

2014-03-10 to present | Research Professor (Institute for Bioscience and Biotechnology Research)
Employment
Source: Self-asserted source
Alexander Andrianov

Education and qualifications (3)

Massachusetts Institute of Technology: Cambridge, MA, US

1991-09-17 to 1993-07-01 | Postdoctoral (Chemical Engineering)
Education
Source: Self-asserted source
Alexander Andrianov

Lomonosov Moscow State University: Moscow, RU

1980-09-01 to 1991-09-16 | Ph.D. (Polymer Chemistry)
Education
Source: Self-asserted source
Alexander Andrianov

Lomonosov Moscow State University: Moscow, RU

1975-09-01 to 1980-09-01 | B.S. (Chemistry Department)
Education
Source: Self-asserted source
Alexander Andrianov

Funding (6)

Rational design and efficacy testing of vaccines against HCV

2022-05-05 to 2027-04-30 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.12884897
GRANT_NUMBER: R01AI168048
Source: Self-asserted source
Alexander Andrianov via DimensionsWizard

Collaborative Research: Conformal Assemblies of Polyphosphazenes with Controlled Biofuncationality

2018-07-15 to 2021-06-30 | Grant
Directorate for Mathematical & Physical Sciences (Arlington, US)
URL: https://app.dimensions.ai/details/grant/grant.7671642
GRANT_NUMBER: 1808531
Source: Self-asserted source
Alexander Andrianov via DimensionsWizard

Structure-Based Vaccine Design for Hepatits C Virus

2017-06-01 to 2022-05-31 | Grant
National Institute of Allergy and Infectious Diseases (n/a, US)
URL: https://grants.uberresearch.com/100000060/R01AI132213/Structure-Based-Vaccine-Design-for-Hepatits-C-Virus
GRANT_NUMBER: R01AI132213
Source: Self-asserted source
Alexander Andrianov via DimensionsWizard

Novel Polyphosphazene Technology for Stabilizing Protein Therapeutics

2017-06 to 2018-03 | Grant
Maryland Innovation Initiative, TEDCO (Columbia, MD, US)
GRANT_NUMBER:

2017-MII-3977
Source: Self-asserted source
Alexander Andrianov

Polyphosphazene Presenters for the Mulitmeric Protein Malaria Vaccine

2003-10-01 to 2004-09-30 | Grant
Department of Defense, Small Business Innovation Research (Washington, US)
URL: https://grants.uberresearch.com/100000005/132082/Polyphosphazene-Presenters-for-the-Mulitmeric-Protein-Malaria-Vaccine
GRANT_NUMBER: 132082
Source: Self-asserted source
Alexander Andrianov via DimensionsWizard

Development of an Intranasal Rotavirus Subunit Vaccine

2002-07-15 to 2003-03-14 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, US)
GRANT_NUMBER: 1R43AI052669-01
GRANT_NUMBER: 1R43AI052669-01
Source: Self-asserted source
Alexander Andrianov via DimensionsWizard

Works (50 of 102)

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Protein–polyelectrolyte complexation: effects of sterically repulsive groups, macromolecular architecture and hierarchical assembly

Soft Matter
2025 | Journal article
DOI: 10.1039/D4SM01254B
Contributors: Raman Hlushko; Alexander Marin; Alexander K. Andrianov
Source: check_circle
Crossref

Virus-Mimicking Polymer Nanocomplexes Co-Assembling HCV E1E2 and Core Proteins with TLR 7/8 Agonist—Synthesis, Characterization, and In Vivo Activity

Journal of Functional Biomaterials
2025-01-19 | Journal article
DOI: 10.3390/jfb16010034
Contributors: Thomas R. Fuerst; Alexander Marin; Sarah Jeong; Liudmila Kulakova; Raman Hlushko; Katrina Gorga; Eric A. Toth; Nevil J. Singh; Alexander K. Andrianov
Source: check_circle
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Hydrolytically Degradable Zwitterionic Polyphosphazene Containing HEPES Moieties as Side Groups

Biomacromolecules
2024-10-14 | Journal article
DOI: 10.1021/acs.biomac.4c01008
Contributors: Harichandra D. Tagad; Alexander Marin; Raman Hlushko; Alexander K. Andrianov
Source: check_circle
Crossref

Directly visualizing individual polyorganophosphazenes and their single-chain complexes with proteins

Communications Materials
2024-03-14 | Journal article
DOI: 10.1038/s43246-024-00476-6
Contributors: Raman Hlushko; Edwin Pozharski; Vivek M. Prabhu; Alexander K. Andrianov
Source: check_circle
Crossref

Immunopotentiating Polyphosphazene Delivery Systems: Supramolecular Self-Assembly and Stability in the Presence of Plasma Proteins

Molecular Pharmaceutics
2024-02-05 | Journal article
DOI: 10.1021/acs.molpharmaceut.3c00916
Contributors: Alexander Marin; Sri H. Kethanapalli; Alexander K. Andrianov
Source: check_circle
Crossref

Engineering Degradation Rate of Polyphosphazene-Based Layer-by-Layer Polymer Coatings

Journal of Functional Biomaterials
2024-01-23 | Journal article
DOI: 10.3390/jfb15020026
Contributors: Jordan Brito; Junho Moon; Raman Hlushko; Aliaksei Aliakseyeu; Alexander K. Andrianov; Svetlana A. Sukhishvili
Source: check_circle
Crossref
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Cryo-EM and AFM visualize linear polyorganophosphazene: individual chains and single-chain assemblies with proteins

2023-10-31 | Preprint
DOI: 10.21203/rs.3.rs-3411603/v1
Contributors: Alexander Andrianov; Raman Hlushko; Edvin Pozharski; Vivek Prabhu
Source: check_circle
Crossref

Monitoring Protein Complexation with Polyphosphazene Polyelectrolyte Using Automated Dynamic Light Scattering Titration and Asymmetric Flow Field Flow Fractionation and Protein Recognition Immunoassay

ACS Polymers Au
2023-10-11 | Journal article
DOI: 10.1021/acspolymersau.3c00006
Contributors: Michael Lueckheide; Alexander Marin; Harichandra D. Tagad; Nicholas D. Posey; Vivek M. Prabhu; Alexander K. Andrianov
Source: check_circle
Crossref

Noncovalent PEGylation of protein and peptide therapeutics

WIREs Nanomedicine and Nanobiotechnology
2023-09 | Journal article
DOI: 10.1002/wnan.1897
Contributors: Alexander K. Andrianov
Source: check_circle
Crossref

Prospects for developing an Hepatitis C virus E1E2‐based nanoparticle vaccine

Reviews in Medical Virology
2023-09 | Journal article
DOI: 10.1002/rmv.2474
Contributors: Eric A. Toth; Alexander K. Andrianov; Thomas R. Fuerst
Source: check_circle
Crossref

Fluorine-Functionalized Polyphosphazene Immunoadjuvant: Synthesis, Solution Behavior and In Vivo Potency

Molecules
2023-05-21 | Journal article
DOI: 10.3390/molecules28104218
Contributors: Harichandra D. Tagad; Alexander Marin; Ruixue Wang; Abdul S. Yunus; Thomas R. Fuerst; Alexander K. Andrianov
Source: check_circle
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4-Methylumbelliferone-Functionalized Polyphosphazene and Its Assembly into Biocompatible Fluorinated Nanocoatings with Selective Antiproliferative Activity

Biomacromolecules
2023-05-08 | Journal article
DOI: 10.1021/acs.biomac.3c00153
Contributors: Harichandra D. Tagad; Jordan Brito; Alexander Marin; Christian Buckley; Haoyu Wang; Jingyu Sun; Svetlana A. Sukhishvili; Hongjun Wang; Alexander K. Andrianov
Source: check_circle
Crossref

Skin Vaccination with Ebola Virus Glycoprotein Using a Polyphosphazene-Based Microneedle Patch Protects Mice against Lethal Challenge

Journal of Functional Biomaterials
2022-12 | Journal article | Author
DOI: 10.3390/jfb14010016
Contributors: Andrey Romanyuk; Ruixue Wang; Alexander Marin; Benjamin M. Janus; Eric I. Felner; Dengning Xia; Yenny Goez-Gazi; 0000-0001-6031-5360; Abdul S. Yunus; Eric Toth et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

Factors Controlling Degradation of Biologically Relevant Synthetic Polymers in Solution and Solid State

ACS Applied Bio Materials
2022-11-21 | Journal article
DOI: 10.1021/acsabm.2c00694
Contributors: Jordan Brito; Alexander K. Andrianov; Svetlana A. Sukhishvili
Source: check_circle
Crossref

Supramolecular Protein-Polyelectrolyte Assembly at Near Physiological Conditions—Water Proton NMR, ITC, and DLS Study

Molecules
2022-11-01 | Journal article
DOI: 10.3390/molecules27217424
Contributors: Alexander Marin; Marc B. Taraban; Vanshika Patel; Y. Bruce Yu; Alexander K. Andrianov
Source: check_circle
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grade
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Polyphosphazene: A New Adjuvant Platform for Cocaine Vaccine Development

Molecular Pharmaceutics
2022-09-05 | Journal article
DOI: 10.1021/acs.molpharmaceut.2c00489
Contributors: Mingliang Lin; Alexander Marin; Beverly Ellis; Lisa M. Eubanks; Alexander K. Andrianov; Kim D. Janda
Source: check_circle
Crossref

Hierarchically Structured, All-Aqueous-Coated Hydrophobic Surfaces with pH-Selective Droplet Transfer Capability

ACS Applied Materials & Interfaces
2022-06-08 | Journal article
DOI: 10.1021/acsami.2c04499
Contributors: Jordan Brito; Kaustubh Asawa; Alexander Marin; Alexander K. Andrianov; Chang-Hwan Choi; Svetlana A. Sukhishvili
Source: check_circle
Crossref

Induction of broadly neutralizing antibodies using a secreted form of the hepatitis C virus E1E2 heterodimer as a vaccine candidate.

Proceedings of the National Academy of Sciences of the United States of America
2022-03-09 | Journal article
DOI: 10.1073/pnas.2112008119
PMID: 35263223
PMC: PMC8931252
Source: Self-asserted source
Alexander Andrianov

Cationic Fluoropolyphosphazenes: Synthesis and Assembly with Heparin as a Pathway to Hemocompatible Nanocoatings

ACS Applied Bio Materials
2022-01-17 | Journal article
DOI: 10.1021/acsabm.1c01099
Contributors: Alexander Marin; Jordan Brito; Svetlana A. Sukhishvili; Alexander K. Andrianov
Source: check_circle
Crossref

Nano-Assembly of Quisinostat and Biodegradable Macromolecular Carrier Results in Supramolecular Complexes with Slow-Release Capabilities

Pharmaceutics
2021-11-02 | Journal article
DOI: 10.3390/pharmaceutics13111834
Contributors: Ananda Chowdhury; Alexander Marin; David J. Weber; Alexander K. Andrianov
Source: check_circle
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grade
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Immunopotentiating and Delivery Systems for HCV Vaccines

Viruses
2021-05-25 | Journal article
DOI: 10.3390/v13060981
Contributors: Alexander K. Andrianov; Thomas R. Fuerst
Source: check_circle
Crossref

Next generation polyphosphazene immunoadjuvant: Synthesis, self-assembly and in vivo potency with human papillomavirus VLPs-based vaccine

Nanomedicine: Nanotechnology, Biology and Medicine
2021-04 | Journal article
DOI: 10.1016/j.nano.2021.102359
Part of ISSN: 1549-9634
Contributors: Alexander Marin; Ananda Chowdhury; Sarah M. Valencia; Athina Zacharia; Reinhard Kirnbauer; Richard B.S. Roden; Ligia A. Pinto; Robert H. Shoemaker; Jason D. Marshall; Alexander K. Andrianov
Source: Self-asserted source
Alexander Andrianov via Crossref Metadata Search

Ionic Fluoropolyphosphazenes as Potential Adhesive Agents for Dental Restoration Applications

Regenerative Engineering and Translational Medicine
2021-03-19 | Journal article
DOI: 10.1007/s40883-020-00192-w
Contributors: Michael D. Weir; Papatya Kaner; Alexander Marin; Alexander K. Andrianov
Source: check_circle
Crossref

Improvement of RG1-VLP vaccine performance in BALB/c mice by substitution of alhydrogel with the next generation polyphosphazene adjuvant PCEP

Human Vaccines & Immunotherapeutics
2021-02-11 | Journal article
DOI: 10.1080/21645515.2021.1875763
Part of ISSN: 2164-5515
Contributors: Sarah M. Valencia; Athina Zacharia; Alexander Marin; Rebecca L. Matthews; Chia-Kuei Wu; Breana Myers; Chelsea Sanders; Simone Difilippantonio; Reinhard Kirnbauer; Richard B. Roden et al.
Source: Self-asserted source
Alexander Andrianov via Crossref Metadata Search

Intracellular Delivery of Active Proteins by Polyphosphazene Polymers

Pharmaceutics
2021-02-10 | Journal article
DOI: 10.3390/pharmaceutics13020249
Contributors: Bareera Qamar; Melani Solomon; Alexander Marin; Thomas R. Fuerst; Alexander K. Andrianov; Silvia Muro
Source: check_circle
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Polyphosphazene immunoadjuvants: Historical perspective and recent advances

Journal of Controlled Release
2021-01 | Journal article
DOI: 10.1016/j.jconrel.2020.12.001
Part of ISSN: 0168-3659
Contributors: Alexander K. Andrianov; Robert Langer
Source: Self-asserted source
Alexander Andrianov via Crossref Metadata Search

Polyphosphazenes enable durable, hemocompatible, highly efficient antibacterial coatings

Biomaterials
2021-01 | Journal article
DOI: 10.1016/j.biomaterials.2020.120586
Part of ISSN: 0142-9612
Contributors: Victoria Albright; Daniel Penarete-Acosta; Mary Stack; Jeremy Zheng; Alexander Marin; Hanna Hlushko; Hongjun Wang; Arul Jayaraman; Alexander K. Andrianov; Svetlana A. Sukhishvili
Source: Self-asserted source
Alexander Andrianov via Crossref Metadata Search

Design of a native-like secreted form of the hepatitis C virus E1E2 heterodimer

Proceedings of the National Academy of Sciences
2021-01-11 | Journal article
DOI: 10.1073/pnas.2015149118
Part of ISSN: 0027-8424
Contributors: Johnathan D. Guest; Ruixue Wang; Khadija H. Elkholy; Andrezza Chagas; Kinlin L. Chao; Thomas E. Cleveland; Young Chang Kim; Zhen-Yong Keck; Alexander Marin; Abdul S. Yunus et al.
Source: Self-asserted source
Alexander Andrianov via Crossref Metadata Search

Protein-loaded soluble and nanoparticulate formulations of ionic polyphosphazenes and their interactions on molecular and cellular levels

Materials Science and Engineering C
2020 | Journal article
DOI: 10.1016/j.msec.2019.110179
EID:

2-s2.0-85072034679
Contributors: Andrianov, A.K.; Marin, A.; Deng, J.; Fuerst, T.R.
Source: Self-asserted source
Alexander Andrianov via Scopus - Elsevier

Structure-based design of hepatitis C virus E2 glycoprotein improves serum binding and cross-neutralization

Journal of Virology
2020-09-02 | Journal article
DOI: 10.1128/jvi.00704-20
Part of ISSN: 0022-538X
Part of ISSN: 1098-5514
Source: Self-asserted source
Alexander Andrianov

In Vivo and In Vitro Potency of Polyphosphazene Immunoadjuvants with Hepatitis C Virus Antigen and the Role of Their Supramolecular Assembly.

Molecular pharmaceutics
2020-06-12 | Journal article
DOI: 10.1021/acs.molpharmaceut.0c00487
PMID: 32530637
Source: Self-asserted source
Alexander Andrianov
grade
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Supramolecular Assembly of Toll-like Receptor 7/8 Agonist into Multimeric Water-Soluble Constructs Enables Superior Immune Stimulation In Vitro and In Vivo

ACS Applied Bio Materials
2020-05-18 | Journal article
DOI: 10.1021/acsabm.0c00189
Contributors: Alexander K. Andrianov; Alexander Marin; Ruixue Wang; Hatice Karauzum; Ananda Chowdhury; Pragati Agnihotri; Abdul S. Yunus; Roy A. Mariuzza; Thomas R. Fuerst
Source: check_circle
Crossref

New Family of Water-Soluble Sulfo–Fluoro Polyphosphazenes and Their Assembly within Hemocompatible Nanocoatings

ACS Applied Bio Materials
2019-09-16 | Journal article
DOI: 10.1021/acsabm.9b00485
Contributors: Victoria Albright; Alexander Marin; Papatya Kaner; Svetlana A. Sukhishvili; Alexander K. Andrianov
Source: check_circle
Crossref
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Preface

ACS Symposium Series
2018 | Book
DOI: 10.1021/bk-2018-1298.pr001
EID:

2-s2.0-85052654789
Contributors: Andrianov, A.K.; Allcock, H.R.
Source: Self-asserted source
Alexander Andrianov via Scopus - Elsevier

Hydrolytically Degradable PEGylated Polyelectrolyte Nanocomplexes for Protein Delivery

Biomacromolecules
2018-06 | Journal article
DOI: 10.1021/acs.biomac.8b00785
Part of ISSN: 1525-7797
Contributors: Alexander K. Andrianov; Alexander Marin; Andre Paul Martinez; Jacob L. Weidman; Thomas R. Fuerst
Source: Self-asserted source
Alexander Andrianov via Crossref Metadata Search
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Biocompatible Nanocoatings of Fluorinated Polyphosphazenes through Aqueous Assembly

ACS Applied Materials & Interfaces
2018-03 | Journal article
DOI: 10.1021/acsami.8b02072
Part of ISSN: 1944-8244
Contributors: Victor Selin; Victoria Albright; John F. Ankner; Alexander Marin; Alexander K. Andrianov; Svetlana A. Sukhishvili
Source: Self-asserted source
Alexander Andrianov via Crossref Metadata Search
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Rational design of a trispecific antibody targeting the HIV-1 Env with elevated anti-viral activity

Nature Communications
2018-02 | Journal article
DOI: 10.1038/s41467-018-03335-4
Part of ISSN: 2041-1723
Contributors: James J. Steinhardt; Javier Guenaga; Hannah L. Turner; Krisha McKee; Mark K. Louder; Sijy O’Dell; Chi-I Chiang; Lin Lei; Andrey Galkin; Alexander K. Andrianov et al.
Source: Self-asserted source
Alexander Andrianov via Crossref Metadata Search
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Biodegradable “Scaffold” Polyphosphazenes for Non-Covalent PEGylation of Proteins

Polyphosphazenes in Biomedicine, Engineering, and Pioneering Synthesis
2018-01-01 | Book chapter
DOI: 10.1021/bk-2018-1298.ch006
Source: Self-asserted source
Alexander Andrianov
grade
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Fluorinated Polyphosphazene Coatings Using Aqueous Nano-Assembly of Polyphosphazene Polyelectrolytes

Polyphosphazenes in Biomedicine, Engineering, and Pioneering Synthesis
2018-01-01 | Book chapter
DOI: 10.1021/bk-2018-1298.ch005
Source: Self-asserted source
Alexander Andrianov
grade
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Self-Assembling Ionic Polyphosphazenes and Their Biomedical Applications

Polyphosphazenes in Biomedicine, Engineering, and Pioneering Synthesis
2018-01-01 | Book chapter
DOI: 10.1021/bk-2018-1298.ch002
Source: Self-asserted source
Alexander Andrianov
grade
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PCPP-Adjuvanted Respiratory Syncytial Virus (RSV) sF Subunit Vaccine: Self-Assembled Supramolecular Complexes Enable Enhanced Immunogenicity and Protection

Molecular Pharmaceutics
2017-07-03 | Journal article
DOI: 10.1021/acs.molpharmaceut.7b00118
Contributors: Corinne Cayatte; Alexander Marin; Gaurav Manohar Rajani; Kirsten Schneider-Ohrum; Angie Snell Bennett; Jason D. Marshall; Alexander K. Andrianov
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Biodegradable “Smart” Polyphosphazenes with Intrinsic Multifunctionality as Intracellular Protein Delivery Vehicles

Biomacromolecules
2017-06-12 | Journal article
DOI: 10.1021/acs.biomac.7b00537
Contributors: Andre P. Martinez; Bareera Qamar; Thomas R. Fuerst; Silvia Muro; Alexander K. Andrianov
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Crossref
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Self-assembly of polyphosphazene immunoadjuvant with poly(ethylene oxide) enables advanced nanoscale delivery modalities and regulated pH-dependent cellular membrane activity

Heliyon
2016 | Journal article
DOI: http://dx.doi.org/10.1016/j.heliyon.2016.e00102
Source: Self-asserted source
Alexander Andrianov
grade
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Molecular-Level Interactions of Polyphosphazene Immunoadjuvants and Their Potential Role in Antigen Presentation and Cell Stimulation

Biomacromolecules
2016-10 | Journal article
DOI: 10.1021/acs.biomac.6b01251
Contributors: Alexander K. Andrianov; Alexander Marin; Thomas R. Fuerst
Source: Self-asserted source
Alexander Andrianov via Crossref Metadata Search
grade
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Biodegradable Polyphosphazene Based Peptide-Polymer Hybrids

Polymers
2016-04-22 | Journal article
DOI: 10.3390/polym8040161
Contributors: Anne Linhardt; Michael König; Wolfgang Schöfberger; Oliver Brüggemann; Alexander Andrianov; Ian Teasdale
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Crossref
grade
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Polyionic vaccine adjuvants: another look at aluminum salts and polyelectrolytes

Clinical and Experimental Vaccine Research
2015 | Journal article
DOI: 10.7774/cevr.2015.4.1.23
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Crossref

The effect of stable macromolecular complexes of ionic polyphosphazene on HIV Gag antigen and on activation of human dendritic cells and presentation to T-cells

2014 | Journal article
DOI:

10.1016/j.biomaterials.2014.06.043

EID:

2-s2.0-84905504230
Contributors: Palmer, C.D.; Ninković, J.; Prokopowicz, Z.M.; Mancuso, C.J.; Marin, A.; Andrianov, A.K.; Dowling, D.J.; Levy, O.
Source: Self-asserted source
Alexander Andrianov via Scopus - Elsevier

Microneedles for intradermal vaccination: Immunopotentiation and formulation aspects

Novel Immune Potentiators and Delivery Technologies for Next Generation Vaccines
2013 | Book chapter
Part of DOI: 10.1007/978-1-4614-5380-2_10
EID:

2-s2.0-84929526536
Contributors: Andrianov, A.K.
Source: Self-asserted source
Alexander Andrianov via Scopus - Elsevier

Intradermal immunization using coated microneedles containing an immunoadjuvant

2012 | Journal article
DOI:

10.1016/j.vaccine.2011.09.062

EID:

2-s2.0-84861994663
Contributors: Andrianov, A.K.; Mutwiri, G.
Source: Self-asserted source
Alexander Andrianov via Scopus - Elsevier

Carboxymethylcellulose-Chitosan-coated microneedles with modulated hydration properties

2011 | Journal article
DOI:

10.1002/app.33608

EID:

2-s2.0-79953694472
Contributors: Marin, A.; Andrianov, A.K.
Source: Self-asserted source
Alexander Andrianov via Scopus - Elsevier
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Peer review (23 reviews for 15 publications/grants)

Review activity for ACS applied nano materials. (1)
Review activity for ACS applied polymer materials. (1)
Review activity for ACS biomaterials science & engineering. (1)
Review activity for ACS macro letters. (1)
Review activity for Biomacromolecules. (5)
Review activity for European journal of inorganic chemistry. (1)
Review activity for Industrial & engineering chemistry research. (1)
Review activity for Langmuir : (2)
Review activity for Macromolecular chemistry and physics. (1)
Review activity for Macromolecules. (1)
Review activity for Molecular pharmaceutics. (2)
Review activity for Monatshefte für Chemie. (1)
Review activity for Nanomaterials. (1)
Review activity for Pharmaceutics. (2)
Review activity for Regenerative engineering and translational medicine. (2)
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