Personal information

Countries

China

Activities

Collapse all

Employment (1)

Sloan Kettering Institute: New York, NY, US

2024-05-09 to present | Research Fellow (Piro lito lab)
Employment
Source: check_circle
Memorial Sloan Kettering Cancer Center

Works (19)

Structure-Based Design and Discovery of a Potent and Cell-Active LC3A/B Covalent Inhibitor

Journal of Medicinal Chemistry
2024-07-25 | Journal article
DOI: 10.1021/acs.jmedchem.4c00898
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Contributors: Zhenfei Zhou; Siqi Huang; Shijie Fan; Xueyuan Li; Chengyu Wang; Wanlin Yu; Daohai Du; yuanyuan zhang; Kaixian Chen; Wei Fu et al.
Source: Self-asserted source
Shijie Fan

Data from PRMT1 Inhibition Activates the Interferon Pathway to Potentiate Antitumor Immunity and Enhance Checkpoint Blockade Efficacy in Melanoma

2024-02-01 | Preprint
DOI: 10.1158/0008-5472.c.7054136
Contributors: Hongru Tao; Chen Jin; Liyuan Zhou; Zhenzhong Deng; Xiao Li; Wenzhen Dang; Shijie Fan; Bing Li; Fei Ye; Junyan Lu et al.
Source: check_circle
Crossref

Data from PRMT1 Inhibition Activates the Interferon Pathway to Potentiate Antitumor Immunity and Enhance Checkpoint Blockade Efficacy in Melanoma

2024-02-01 | Preprint
DOI: 10.1158/0008-5472.c.7054136.v1
Contributors: Hongru Tao; Chen Jin; Liyuan Zhou; Zhenzhong Deng; Xiao Li; Wenzhen Dang; Shijie Fan; Bing Li; Fei Ye; Junyan Lu et al.
Source: check_circle
Crossref

PRMT1 Inhibition Activates the Interferon Pathway to Potentiate Antitumor Immunity and Enhance Checkpoint Blockade Efficacy in Melanoma

Cancer Research
2024-02-01 | Journal article
DOI: 10.1158/0008-5472.CAN-23-1082
Contributors: Hongru Tao; Chen Jin; Liyuan Zhou; Zhenzhong Deng; Xiao Li; Wenzhen Dang; Shijie Fan; Bing Li; Fei Ye; Junyan Lu et al.
Source: check_circle
Crossref

Supplementary Data from PRMT1 Inhibition Activates the Interferon Pathway to Potentiate Antitumor Immunity and Enhance Checkpoint Blockade Efficacy in Melanoma

2024-02-01 | Preprint
DOI: 10.1158/0008-5472.25124762
Contributors: Hongru Tao; Chen Jin; Liyuan Zhou; Zhenzhong Deng; Xiao Li; Wenzhen Dang; Shijie Fan; Bing Li; Fei Ye; Junyan Lu et al.
Source: check_circle
Crossref

Supplementary Data from PRMT1 Inhibition Activates the Interferon Pathway to Potentiate Antitumor Immunity and Enhance Checkpoint Blockade Efficacy in Melanoma

2024-02-01 | Preprint
DOI: 10.1158/0008-5472.25124768
Contributors: Hongru Tao; Chen Jin; Liyuan Zhou; Zhenzhong Deng; Xiao Li; Wenzhen Dang; Shijie Fan; Bing Li; Fei Ye; Junyan Lu et al.
Source: check_circle
Crossref

Supplementary Data from PRMT1 Inhibition Activates the Interferon Pathway to Potentiate Antitumor Immunity and Enhance Checkpoint Blockade Efficacy in Melanoma

2024-02-01 | Preprint
DOI: 10.1158/0008-5472.25124768.v1
Contributors: Hongru Tao; Chen Jin; Liyuan Zhou; Zhenzhong Deng; Xiao Li; Wenzhen Dang; Shijie Fan; Bing Li; Fei Ye; Junyan Lu et al.
Source: check_circle
Crossref

Supplementary Data from PRMT1 Inhibition Activates the Interferon Pathway to Potentiate Antitumor Immunity and Enhance Checkpoint Blockade Efficacy in Melanoma

2024-02-01 | Preprint
DOI: 10.1158/0008-5472.25124762.v1
Contributors: Hongru Tao; Chen Jin; Liyuan Zhou; Zhenzhong Deng; Xiao Li; Wenzhen Dang; Shijie Fan; Bing Li; Fei Ye; Junyan Lu et al.
Source: check_circle
Crossref

An ATG4B inhibitor blocks autophagy and sensitizes Sorafenib inhibition activities in HCC tumor cells

Bioorganic & Medicinal Chemistry
2023-04 | Journal article
DOI: 10.1016/j.bmc.2023.117262
Part of ISSN: 0968-0896
Contributors: Yanqiu Xie; Shijie Fan; Dongxuan Ni; Wei Wan; Pan Xu; Yiluan Ding; Ruihan Zhang; Jing Lu; Naixia Zhang; Yuanyuan Zhang et al.
Source: Self-asserted source
Shijie Fan
grade
Preferred source (of 2)‎

Cyclization strategy leads to highly potent Bromodomain and extra-terminal (BET) Bromodomain inhibitors for the treatment of acute liver injury

European Journal of Medicinal Chemistry
2023-02 | Journal article
DOI: 10.1016/j.ejmech.2022.115023
Part of ISSN: 0223-5234
Contributors: Chao Chen; Tian Lu; Panyu Chen; Zizhou Li; Yaxi Yang; Shijie Fan; Yuanyuan Zhang; Kaixian Chen; Wei Fu; Yugang Wang et al.
Source: Self-asserted source
Shijie Fan

Histone deacetylase inhibitor givinostat attenuates nonalcoholic steatohepatitis and liver fibrosis

Acta Pharmacologica Sinica
2022-04 | Journal article
DOI: 10.1038/s41401-021-00725-1
Part of ISSN: 1671-4083
Part of ISSN: 1745-7254
Contributors: He-ming Huang; Shi-jie Fan; Xiao-ru Zhou; Yan-jun Liu; Xiao Li; Li-ping Liao; Jing Huang; Cui-cui Shi; Liang Yu; Rong Fu et al.
Source: Self-asserted source
Shijie Fan

P300/CBP inhibition sensitizes mantle cell lymphoma to PI3Kδ inhibitor idelalisib

Acta Pharmacologica Sinica
2022-02 | Journal article
DOI: 10.1038/s41401-021-00643-2
Part of ISSN: 1671-4083
Part of ISSN: 1745-7254
Contributors: Xiao-ru Zhou; Xiao Li; Li-ping Liao; Jie Han; Jing Huang; Jia-cheng Li; Hong-ru Tao; Shi-jie Fan; Zhi-feng Chen; Qi Li et al.
Source: Self-asserted source
Shijie Fan

Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein

Angewandte Chemie International Edition
2021-12-06 | Journal article
DOI: 10.1002/anie.202109464
Part of ISSN: 1433-7851
Part of ISSN: 1521-3773
Contributors: Shijie Fan; Liyan Yue; Wei Wan; Yuanyuan Zhang; Bidong Zhang; Chinatsu Otomo; Quanfu Li; Tingting Lin; Junchi Hu; Pan Xu et al.
Source: Self-asserted source
Shijie Fan

Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2–EED Interaction

Journal of Medicinal Chemistry
2021-06-24 | Journal article
DOI: 10.1021/acs.jmedchem.0c02261
Part of ISSN: 0022-2623
Part of ISSN: 1520-4804
Contributors: Daohai Du; Dandan Xu; Licheng Zhu; Giulia Stazi; Clemens Zwergel; Yanli Liu; Zhongyuan Luo; Yuanqing Li; yuanyuan zhang; Kongkai Zhu et al.
Source: Self-asserted source
Shijie Fan

Cyclin-dependent kinase inhibitor roscovitine attenuates liver inflammation and fibrosis by influencing initiating steps of liver injury

Clinical Science
2021-04-16 | Journal article
DOI: 10.1042/cs20201111
Part of ISSN: 0143-5221
Part of ISSN: 1470-8736
Contributors: Yanjun Liu; Jiacheng Li; Liping Liao; Heming Huang; Shijie Fan; Rong Fu; Jing Huang; Cuicui Shi; Liang Yu; Kai-xian Chen et al.
Source: Self-asserted source
Shijie Fan

Histone deacetylase inhibitor givinostat alleviates liver fibrosis by regulating hepatic stellate cell activation

Molecular Medicine Reports
2021-02-26 | Journal article
DOI: 10.3892/mmr.2021.11944
Part of ISSN: 1791-2997
Part of ISSN: 1791-3004
Contributors: He-Ming Huang; Xiao-Ru Zhou; Yan-Jun Liu; Shi-Jie Fan; Li-Ping Liao; Jing Huang; Cui-Cui Shi; Liang Yu; Jin-Jin Pen; Cheng Luo et al.
Source: Self-asserted source
Shijie Fan

The dynamic conformational landscape of the protein methyltransferase SETD8

eLife
2019-05-13 | Journal article
DOI: 10.7554/elife.45403
Part of ISSN: 2050-084X
Contributors: Shi Chen; Rafal Wiewiora; Fanwang Meng; Nicolas Babault; Anqi Ma; Wenyu Yu; Kun Qian; Hao Hu; Hua Zou; Junyi Wang et al.
Source: Self-asserted source
Shijie Fan
grade
Preferred source (of 2)‎

Machine Learning Methods in Precision Medicine Targeting Epigenetic Diseases

Current Pharmaceutical Design
2019-01-22 | Journal article
DOI: 10.2174/1381612824666181112114228
Part of ISSN: 1381-6128
Contributors: Shijie Fan; Yu Chen; Cheng Luo; Fanwang Meng
Source: Self-asserted source
Shijie Fan

Development and evaluation of a novel series of Nitroxoline-derived BET inhibitors with antitumor activity in renal cell carcinoma

Oncogenesis
2018-11-02 | Journal article
DOI: 10.1038/s41389-018-0093-z
Part of ISSN: 2157-9024
Contributors: Wei Chen; Hao Zhang; Zhifeng Chen; Hao Jiang; Liping Liao; Shijie Fan; Jing Xing; Yiqian Xie; Shijie Chen; Hong Ding et al.
Source: Self-asserted source
Shijie Fan
How many people are using ORCID?