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Employment (1)

University of Virginia: Charlottesville, VA, US

1999-09-09 to present | Professor (Pharmacology)
Employment
Source: Self-asserted source
Edward Perez-Reyes

Education and qualifications (2)

University of Colorado health Sciences Center: Denver, CO, US

1980-08-20 to 1986-06-01 | Ph.D. (Pharmacology)
Education
Source: Self-asserted source
Edward Perez-Reyes

University of North Carolina: Chapel Hill, NC, US

1976-09-01 to 1978-12-15 | BA Chemistry
Education
Source: Self-asserted source
Edward Perez-Reyes

Funding (13)

Validation of a novel mouse model of temporal lobe epilepsy

2019-08-01 to 2021-07-31 | Grant
National Institute of Neurological Disorders and Stroke (Bethesda, US)
URL: https://app.dimensions.ai/details/grant/grant.8556424
GRANT_NUMBER: R61NS112549
Source: Self-asserted source
Edward Perez-Reyes via DimensionsWizard

Developing a drug-inducible gene therapy for temporal lobe epilepsy

2016-07-01 to 2020-04-30 | Grant
National Institute of Neurological Disorders and Stroke (n/a, US)
URL: https://grants.uberresearch.com/100000065/R01NS097726/Developing-a-drug-inducible-gene-therapy-for-temporal-lobe-epilepsy
GRANT_NUMBER: grant.R01NS097726
Source: Self-asserted source
Edward Perez-Reyes via DimensionsWizard

Probing epileptic circuits with novel Cre- and drug-regulated genetic approaches

2015-02-01 to 2017-01-31 | Grant
National Institute of Neurological Disorders and Stroke (n/a, US)
URL: https://grants.uberresearch.com/100000065/R21NS090843/Probing-epileptic-circuits-with-novel-Cre-and-drug-regulated-genetic-approaches
GRANT_NUMBER: grant.R21NS090843
Source: Self-asserted source
Edward Perez-Reyes via DimensionsWizard

Na Channel beta4 as a Gene Therapy Target for Epilepsy

2012-07-01 to 2014-06-30 | Grant
National Institute of Neurological Disorders and Stroke (n/a, US)
URL: https://grants.uberresearch.com/100000065/R21NS080061/Na-Channel-beta4-as-a-Gene-Therapy-Target-for-Epilepsy
GRANT_NUMBER: grant.R21NS080061
Source: Self-asserted source
Edward Perez-Reyes via DimensionsWizard

Silencing Hyperactive Neurons as a Treatment for Temporal Lobe Epilepsy

2011-07-01 to 2013-12-31 | Grant
Citizens United for Research in Epilepsy (Chicago, US)
URL: https://app.dimensions.ai/details/grant/grant.3868067
GRANT_NUMBER:

259046
Source: Self-asserted source
Edward Perez-Reyes via DimensionsWizard

Neuron-specific block of T-type calcium channels

2011-03-15 to 2013-08-28 | Grant
National Institute of Neurological Disorders and Stroke (n/a, US)
URL: https://grants.uberresearch.com/100000065/R21NS069524/Neuron-specific-block-of-T-type-calcium-channels
GRANT_NUMBER: grant.R21NS069524
Source: Self-asserted source
Edward Perez-Reyes via DimensionsWizard

Mechanisms by which T-type calcium channels increase seizure susceptibility

2009-09-30 to 2011-08-31 | Grant
National Institute of Neurological Disorders and Stroke (n/a, US)
URL: https://grants.uberresearch.com/100000065/R01NS067456/Mechanisms-by-which-T-type-calcium-channels-increase-seizure-susceptibility
GRANT_NUMBER: grant.R01NS067456
Source: Self-asserted source
Edward Perez-Reyes via DimensionsWizard

Development of High Throughput Assays for N-type Calcium Channels

2006-01-01 to 2007-12-31 | Grant
National Institute of Neurological Disorders and Stroke (n/a, US)
URL: https://grants.uberresearch.com/100000065/R21NS051344/Development-of-High-Throughput-Assays-for-N-type-Calcium-Channels
GRANT_NUMBER: grant.R21NS051344
Source: Self-asserted source
Edward Perez-Reyes via DimensionsWizard

Molecular Analysis of Neuronal T Type CA++ Channels

1999-07-05 to 2009-05-31 | Grant
National Institute of Neurological Disorders and Stroke (n/a, US)
URL: https://grants.uberresearch.com/100000065/R01NS038691/Molecular-Analysis-of-Neuronal-T-Type-CA-Channels
GRANT_NUMBER: grant.R01NS038691
Source: Self-asserted source
Edward Perez-Reyes via DimensionsWizard

CLONING AND EXPESSION OF A CARDIAC T TYPE CA CHANNEL

1997-07-01 to 2001-08-31 | Grant
National Heart Lung and Blood Institute (n/a, US)
URL: https://grants.uberresearch.com/100000050/R01HL058728/CLONING-AND-EXPESSION-OF-A-CARDIAC-T-TYPE-CA-CHANNEL
GRANT_NUMBER: grant.R01HL058728
Source: Self-asserted source
Edward Perez-Reyes via DimensionsWizard

FUNCTIONAL CHARACTERIZATION OF CARDIAC CALCIUM CHANNELS

1992-05-05 to 1998-04-30 | Grant
National Heart Lung and Blood Institute (n/a, US)
URL: https://grants.uberresearch.com/100000050/R29HL046702/FUNCTIONAL-CHARACTERIZATION-OF-CARDIAC-CALCIUM-CHANNELS
GRANT_NUMBER: grant.R29HL046702
Source: Self-asserted source
Edward Perez-Reyes via DimensionsWizard

FUNCTIONAL CHARACTERIZATION OF CARDIAC CALCIUM CHANNELS

1991-09-30 to 1992-05-04 | Grant
National Heart Lung and Blood Institute (n/a, US)
URL: https://grants.uberresearch.com/100000050/R55HL046702/FUNCTIONAL-CHARACTERIZATION-OF-CARDIAC-CALCIUM-CHANNELS
GRANT_NUMBER: grant.R55HL046702
Source: Self-asserted source
Edward Perez-Reyes via DimensionsWizard

PRIMARY STRUCTURE OF CALCIUM CHANNELS

1988-11-17 to 1990-01-01 | Grant
National Heart Lung and Blood Institute (n/a, US)
URL: https://grants.uberresearch.com/100000050/F32HL007831/PRIMARY-STRUCTURE-OF-CALCIUM-CHANNELS
GRANT_NUMBER: grant.F32HL007831
Source: Self-asserted source
Edward Perez-Reyes via DimensionsWizard

Works (10)

Preferential superficial cortical layer activation during seizure propagation

Epilepsia
2024-12-24 | Journal article
DOI: 10.1111/epi.18239
Contributors: Anastasia Brodovskaya; Shinnosuke Shiono; Chengsan Sun; Edward Perez‐Reyes; Jaideep Kapur
Source: check_circle
Crossref

EpiPro, a Novel, Synthetic, Activity-Regulated Promoter That Targets Hyperactive Neurons in Epilepsy for Gene Therapy Applications

International Journal of Molecular Sciences
2023-09 | Journal article | Author
DOI: 10.3390/ijms241914467
Contributors: Cassidy T. Burke; Iuliia Vitko; Justyna Straub; Elsa O. Nylund; Agnieszka Gawda; Kathryn Blair; Kyle Sullivan; Lara Ergun; Matteo Ottolini; Manoj K. Patel et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

Drug-Inducible Gene Therapy Effectively Reduces Spontaneous Seizures in Kindled Rats but Creates Off-Target Side Effects in Inhibitory Neurons

International Journal of Molecular Sciences
2023-07 | Journal article | Author
DOI: 10.3390/ijms241411347
Contributors: Kyle Sullivan; Iuliia Vitko; Kathryn Blair; Ronald P. Gaykema; Madison Failor; Jennifer San Pietro; Deblina Dey; John M. Williamson; Ruth L. Stornetta; Jaideep Kapur et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

Voltage-gated calcium channels (Ca<sub>V</sub>) in GtoPdb v.2023.1

IUPHAR/BPS Guide to Pharmacology CITE
2023-04-26 | Journal article
DOI: 10.2218/gtopdb/F80/2023.1
Contributors: William A. Catterall; Edward Perez-Reyes; Terrance P. Snutch; Jörg Striessnig
Source: check_circle
Crossref

Targeting oxidized phospholipids by AAV-based gene therapy in mice with established hepatic steatosis prevents progression to fibrosis

Science Advances
2022-07-15 | Journal article
DOI: 10.1126/sciadv.abn0050
Contributors: Clint M. Upchurch; Scott Yeudall; Caitlin M. Pavelec; Dennis Merk; Jan Greulich; Mohan Manjegowda; Shyam S. Raghavan; Irina M. Bochkis; Michael M. Scott; Edward Perez-Reyes et al.
Source: check_circle
Crossref

Voltage-gated calcium channels (Ca<sub>V</sub>) in GtoPdb v.2021.3

IUPHAR/BPS Guide to Pharmacology CITE
2021-09-02 | Journal article
DOI: 10.2218/gtopdb/F80/2021.3
Contributors: William A. Catterall; Edward Perez-Reyes; Terrance P. Snutch; Jörg Striessnig
Source: check_circle
Crossref

Voltage-gated calcium channels in GtoPdb v.2021.2

IUPHAR/BPS Guide to Pharmacology CITE
2021-06-25 | Journal article
DOI: 10.2218/gtopdb/F80/2021.2
Contributors: William A. Catterall; Edward Perez-Reyes; Terrance P. Snutch; Jörg Striessnig
Source: check_circle
Crossref

Voltage-gated calcium channels (version 2020.5) in the IUPHAR/BPS Guide to Pharmacology Database

IUPHAR/BPS Guide to Pharmacology CITE
2020-11-12 | Journal article
DOI: 10.2218/gtopdb/F80/2020.5
Contributors: William A. Catterall; Edward Perez-Reyes; Terrance P. Snutch; Jörg Striessnig
Source: check_circle
Crossref

Voltage-gated calcium channels (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

IUPHAR/BPS Guide to Pharmacology CITE
2019-09-16 | Journal article
DOI: 10.2218/gtopdb/F80/2019.4
Contributors: William A. Catterall; Edward Perez-Reyes; Terrance P. Snutch; Jörg Striessnig
Source: check_circle
Crossref

Calmodulin regulates Cav3 T-type channels at their gating brake

Journal of Biological Chemistry
2017-12 | Journal article
DOI: 10.1074/jbc.M117.807925
Contributors: Jean Chemin; Valentina Taiakina; Arnaud Monteil; Michael Piazza; Wendy Guan; Robert F. Stephens; Ashraf Kitmitto; Zhiping P. Pang; Annette C. Dolphin; Edward Perez-Reyes et al.
Source: check_circle
Crossref

Peer review (2 reviews for 2 publications/grants)

Review activity for Gene therapy. (1)
Review activity for Molecular therapy. (1)
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