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Scopus Author ID: 8263360100

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Employment (1)

Fondazione Istituto FIRC di Oncologia Molecolare: Milano, Lombardia, IT

2014 to present | Staff Scientist (Molecular Machines in Signaling Pathways research program at IFOM)
Employment
Source: Self-asserted source
elena maspero

Works (25)

Myosin VI regulates ciliogenesis by promoting the turnover of the centrosomal/satellite protein OFD1.

EMBO reports
2021-12 | Journal article
DOI: 10.15252/embr.202154160
PMID: 34957672
Contributors: Magistrati E; Maestrini G; Niño CA; Lince-Faria M; Beznoussenko G; Mironov A; Maspero E; Bettencourt-Dias M; Polo S
Source: Self-asserted source
elena maspero via Europe PubMed Central

Hecw controls oogenesis and neuronal homeostasis by promoting the liquid state of ribonucleoprotein particles.

Nature communications
2021-09 | Journal article
DOI: 10.1038/s41467-021-25809-8
PMID: 34531401
PMC: PMC8446043
Contributors: Fajner V; Giavazzi F; Sala S; Oldani A; Martini E; Napoletano F; Parazzoli D; Cesare G; Cerbino R; Maspero E et al.
Source: Self-asserted source
elena maspero via Europe PubMed Central

The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress.

Cell reports
2021-09 | Journal article
DOI: 10.1016/j.celrep.2021.109694
PMID: 34525372
Contributors: Napoletano F; Ferrari Bravo G; Voto IAP; Santin A; Celora L; Campaner E; Dezi C; Bertossi A; Valentino E; Santorsola M et al.
Source: Self-asserted source
elena maspero via Europe PubMed Central

Ouabain and Digoxin Activate the Proteasome and the Degradation of the ERα in Cells Modeling Primary and Metastatic Breast Cancer

Cancers
2020-12 | Journal article | Author
DOI: 10.3390/cancers12123840
Contributors: Claudia Busonero; Stefano Leone; Fabrizio Bianchi; elena maspero; Marco Fiocchetti; ORAZIO PALUMBO; Manuela Cipolletti; Stefania Bartoloni; Filippo Acconcia
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

USP25 Regulates EGFR Fate by Modulating EGF-Induced Ubiquitylation Dynamics

Biomolecules
2020-11 | Journal article | Author
DOI: 10.3390/biom10111548
Contributors: Carlos A. Niño; Nadine Wollscheid; Giangreco G; elena maspero; Simona Polo
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Clathrin light chain A drives selective myosin VI recruitment to clathrin-coated pits under membrane tension

Nature Communications
2019 | Journal article
DOI: 10.1038/s41467-019-12855-6
EID:

2-s2.0-85074249548

Part of ISSN: 20411723
Contributors: Biancospino, M.; Buel, G.R.; Niño, C.A.; Maspero, E.; di Perrotolo, R.S.; Raimondi, A.; Redlingshöfer, L.; Weber, J.; Brodsky, F.M.; Walters, K.J. et al.
Source: Self-asserted source
elena maspero via Scopus - Elsevier

Detection of ubiquitinated targets in mammalian and Drosophila models

Methods in Enzymology
2019 | Book chapter
DOI: 10.1016/bs.mie.2018.12.030
EID:

2-s2.0-85061249883

Part of ISSN: 15577988 00766879
Contributors: Maspero, E.; Fajner, V.; Weber, J.; Polo, S.
Source: Self-asserted source
elena maspero via Scopus - Elsevier

HECT E3 ligases: A tale with multiple facets

Frontiers in Physiology
2019 | Journal article
DOI: 10.3389/fphys.2019.00370
EID:

2-s2.0-85068220176

Part of ISSN: 1664042X
Contributors: Weber, J.; Polo, S.; Maspero, E.
Source: Self-asserted source
elena maspero via Scopus - Elsevier

Molecularly Distinct Clathrin-Coated Pits Differentially Impact EGFR Fate and Signaling

Cell Reports
2019 | Journal article
DOI: 10.1016/j.celrep.2019.05.017
EID:

2-s2.0-85065903115

Part of ISSN: 22111247
Contributors: Pascolutti, R.; Algisi, V.; Conte, A.; Raimondi, A.; Pasham, M.; Upadhyayula, S.; Gaudin, R.; Maritzen, T.; Barbieri, E.; Caldieri, G. et al.
Source: Self-asserted source
elena maspero via Scopus - Elsevier

β-Sheet Augmentation Is a Conserved Mechanism of Priming HECT E3 Ligases for Ubiquitin Ligation

Journal of Molecular Biology
2018 | Journal article
DOI: 10.1016/j.jmb.2018.06.044
EID:

2-s2.0-85049508547

Part of ISSN: 10898638 00222836
Contributors: Jäckl, M.; Stollmaier, C.; Strohäker, T.; Hyz, K.; Maspero, E.; Polo, S.; Wiesner, S.
Source: Self-asserted source
elena maspero via Scopus - Elsevier

HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation

EMBO Molecular Medicine
2017 | Journal article
DOI: 10.15252/emmm.201606684
EID:

2-s2.0-85007039831

Part of ISSN: 17574684 17574676
Contributors: Myant, K.B.; Cammareri, P.; Hodder, M.C.; Wills, J.; Von Kriegsheim, A.; Győrffy, B.; Rashid, M.; Polo, S.; Maspero, E.; Vaughan, L. et al.
Source: Self-asserted source
elena maspero via Scopus - Elsevier

Targeting HECT-type E3 ligases – insights from catalysis, regulation and inhibitors

FEBS Letters
2017 | Journal article
DOI: 10.1002/1873-3468.12775
EID:

2-s2.0-85028879936

Part of ISSN: 18733468 00145793
Contributors: Fajner, V.; Maspero, E.; Polo, S.
Source: Self-asserted source
elena maspero via Scopus - Elsevier

In vitro ubiquitination: Self-ubiquitination, chain formation, and substrate ubiquitination assays

Methods in Molecular Biology
2016 | Book chapter
DOI: 10.1007/978-1-4939-3756-1_7
EID:

2-s2.0-84987841757

Part of ISSN: 10643745
Contributors: Maspero, E.; Polo, S.
Source: Self-asserted source
elena maspero via Scopus - Elsevier

USP9X Controls EGFR Fate by Deubiquitinating the Endocytic Adaptor Eps15

Current Biology
2016 | Journal article
DOI: 10.1016/j.cub.2015.11.050
EID:

2-s2.0-84959523268

Part of ISSN: 09609822
Contributors: Savio, M.G.; Wollscheid, N.; Cavallaro, E.; Algisi, V.; Di Fiore, P.P.; Sigismund, S.; Maspero, E.; Polo, S.
Source: Self-asserted source
elena maspero via Scopus - Elsevier

Structural and functional framework for the autoinhibition of nedd4-family ubiquitin ligases

Structure
2014 | Journal article
DOI: 10.1016/j.str.2014.09.006
EID:

2-s2.0-84908510945

Part of ISSN: 18784186 09692126
Contributors: Mari, S.; Ruetalo, N.; Maspero, E.; Stoffregen, M.C.; Pasqualato, S.; Polo, S.; Wiesner, S.
Source: Self-asserted source
elena maspero via Scopus - Elsevier

Tyrosine phosphorylation of NEDD4 activates its ubiquitin ligase activity

Science Signaling
2014 | Journal article
DOI: 10.1126/scisignal.2005290
EID:

2-s2.0-84908454158

Part of ISSN: 19379145 19450877
Contributors: Persaud, A.; Alberts, P.; Mari, S.; Tong, J.; Murchie, R.; Maspero, E.; Safi, F.; Moran, M.F.; Polo, S.; Rotin, D.
Source: Self-asserted source
elena maspero via Scopus - Elsevier

Molecular mechanism of ubiquitin-dependent traffic

Vesicle Trafficking in Cancer
2013 | Book chapter
Part of DOI: 10.1007/978-1-4614-6528-7_10
EID:

2-s2.0-84949176444
Contributors: Maspero, E.; Wollscheid, H.-P.; Polo, S.
Source: Self-asserted source
elena maspero via Scopus - Elsevier

Structure of a ubiquitin-loaded HECT ligase reveals the molecular basis for catalytic priming

Nature Structural and Molecular Biology
2013 | Journal article
DOI: 10.1038/nsmb.2566
EID:

2-s2.0-84878900697

Part of ISSN: 15459993 15459985
Contributors: Maspero, E.; Valentini, E.; Mari, S.; Cecatiello, V.; Soffientini, P.; Pasqualato, S.; Polo, S.
Source: Self-asserted source
elena maspero via Scopus - Elsevier

The LXR-IDOL axis defines a clathrin-, caveolae -, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation

Journal of Lipid Research
2013 | Journal article
DOI: 10.1194/jlr.M037713
EID:

2-s2.0-84881247296

Part of ISSN: 00222275 15397262
Contributors: Sorrentino, V.; Nelson, J.K.; Maspero, E.; Marques, A.R.A.; Scheer, L.; Polo, S.; Zelcer, N.
Source: Self-asserted source
elena maspero via Scopus - Elsevier

Threshold-controlled ubiquitination of the EGFR directs receptor fate

EMBO Journal
2013 | Journal article
DOI: 10.1038/emboj.2013.149
EID:

2-s2.0-84881446387

Part of ISSN: 02614189 14602075
Contributors: Sigismund, S.; Algisi, V.; Nappo, G.; Conte, A.; Pascolutti, R.; Cuomo, A.; Bonaldi, T.; Argenzio, E.; Verhoef, L.G.G.C.; Maspero, E. et al.
Source: Self-asserted source
elena maspero via Scopus - Elsevier

A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase

Cell Cycle
2012 | Journal article
DOI: 10.4161/cc.20919
EID:

2-s2.0-84863793933

Part of ISSN: 15514005 15384101
Contributors: Gatti, M.; Pinato, S.; Maspero, E.; Soffientini, P.; Polo, S.; Penengo, L.
Source: Self-asserted source
elena maspero via Scopus - Elsevier

Structure of the HECT:ubiquitin complex and its role in ubiquitin chain elongation

EMBO Reports
2011 | Journal article
DOI: 10.1038/embor.2011.21
EID:

2-s2.0-79953325889

Part of ISSN: 1469221X 14693178
Contributors: Maspero, E.; Mari, S.; Valentini, E.; Musacchio, A.; Fish, A.; Pasqualato, S.; Polo, S.
Source: Self-asserted source
elena maspero via Scopus - Elsevier

A two-tiered mechanism of EGFR inhibition by RALT/MIG6 via kinase suppression and receptor degradation

Journal of Cell Biology
2010 | Journal article
DOI: 10.1083/jcb.201002032
EID:

2-s2.0-77951785332

Part of ISSN: 00219525 00219525
Contributors: Frosi, Y.; Anastasi, S.; Ballarò, C.; Varsano, G.; Castellani, L.; Maspero, E.; Polo, S.; Alemà, S.; Segatto, O.
Source: Self-asserted source
elena maspero via Scopus - Elsevier

Molecular mechanisms of coupled monoubiquitination

Nature Cell Biology
2006 | Journal article
DOI: 10.1038/ncb1484
EID:

2-s2.0-33750532531

Part of ISSN: 14657392
Contributors: Woelk, T.; Oldrini, B.; Maspero, E.; Confalonieri, S.; Cavallaro, E.; Di Fiore, P.P.; Polo, S.
Source: Self-asserted source
elena maspero via Scopus - Elsevier

Clathrin-independent endocytosis of ubiquitinated cargos

Proceedings of the National Academy of Sciences of the United States of America
2005 | Journal article
DOI: 10.1073/pnas.0409817102
EID:

2-s2.0-14544306526

Part of ISSN: 00278424
Contributors: Sigismund, S.; Woelk, T.; Puri, C.; Maspero, E.; Tacchetti, C.; Transidico, P.; Di Fiore, P.P.; Polo, S.
Source: Self-asserted source
elena maspero via Scopus - Elsevier

Peer review (1 review for 1 publication/grant)

Review activity for Nature communications (1)
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