Personal information

Biography

Dedicated researcher with thorough experience in in vitro and in vivo cancer immunotherapy and tumor immunology. Track record of publications in peer-reviewed journals and book chapters and author of a patent. Expertise in cell culture, immunoassays, microbiology, electronic & confocal microscopy, and lung, melanoma and bladder cancer mouse models. Proficient at quickly learning new laboratory skills, as well as enthusiastic about teaching lab members. Organized and detail-oriented. Always approaching projects with a hard-working nature.

Activities

Employment (2)

University of Pennsylvania: Philadelphia, PA, US

2019-01-08 to present | Post-doc (Pulmonary, Allergy, and Critical Care Division, Perelman School of Medicine)
Employment
Source: Self-asserted source
Estela Noguera-Ortega

University of Pennsylvania: Philadelphia, PA, US

2017-09-01 to 2019-01-07 | Post-doc (Hematology / Oncology Department, Perelman School of Medicine)
Employment
Source: Self-asserted source
Estela Noguera-Ortega

Education and qualifications (1)

Universitat Autònoma de Barcelona: Barcelona, Catalunya, ES

2011-09-01 to 2015-11-27 | PhD (Genetics and Microbiology Department)
Education
Source: Self-asserted source
Estela Noguera-Ortega

Professional activities (1)

American Association for Cancer Research: Philadelphia, PA, US

2018-10-09 to present
Membership
Source: Self-asserted source
Estela Noguera-Ortega

Works (26)

Desmoplastic stroma restricts T cell extravasation and mediates immune exclusion and immunosuppression in solid tumors

Nature Communications
2023-08-22 | Journal article
Contributors: Zebin Xiao; Leslie Todd; Li Huang; Estela Noguera-Ortega; Zhen Lu; Lili Huang; Meghan Kopp; Yue Li; Nimisha Pattada; Wenqun Zhong et al.
Source: check_circle
Crossref

Data from Monitoring Therapeutic Response to Anti-FAP CAR T Cells Using [<sup>18</sup>F]AlF-FAPI-74

2023-04-01 | Preprint
Contributors: Iris K. Lee; Estela Noguera-Ortega; Zebin Xiao; Leslie Todd; John Scholler; Decheng Song; Maria Liousia; Katheryn Lohith; Kexiang Xu; Kimberly J. Edwards et al.
Source: check_circle
Crossref

Data from Monitoring Therapeutic Response to Anti-FAP CAR T Cells Using [<sup>18</sup>F]AlF-FAPI-74

2023-04-01 | Preprint
Contributors: Iris K. Lee; Estela Noguera-Ortega; Zebin Xiao; Leslie Todd; John Scholler; Decheng Song; Maria Liousia; Katheryn Lohith; Kexiang Xu; Kimberly J. Edwards et al.
Source: check_circle
Crossref

Supplementary Data from Monitoring Therapeutic Response to Anti-FAP CAR T Cells Using [<sup>18</sup>F]AlF-FAPI-74

2023-04-01 | Preprint
Contributors: Iris K. Lee; Estela Noguera-Ortega; Zebin Xiao; Leslie Todd; John Scholler; Decheng Song; Maria Liousia; Katheryn Lohith; Kexiang Xu; Kimberly J. Edwards et al.
Source: check_circle
Crossref

Supplementary Data from Monitoring Therapeutic Response to Anti-FAP CAR T Cells Using [<sup>18</sup>F]AlF-FAPI-74

2023-04-01 | Preprint
Contributors: Iris K. Lee; Estela Noguera-Ortega; Zebin Xiao; Leslie Todd; John Scholler; Decheng Song; Maria Liousia; Katheryn Lohith; Kexiang Xu; Kimberly J. Edwards et al.
Source: check_circle
Crossref

Supplementary Data from Monitoring Therapeutic Response to Anti-FAP CAR T Cells Using [<sup>18</sup>F]AlF-FAPI-74

2023-04-01 | Preprint
Contributors: Iris K. Lee; Estela Noguera-Ortega; Zebin Xiao; Leslie Todd; John Scholler; Decheng Song; Maria Liousia; Katheryn Lohith; Kexiang Xu; Kimberly J. Edwards et al.
Source: check_circle
Crossref

Supplementary Data from Monitoring Therapeutic Response to Anti-FAP CAR T Cells Using [<sup>18</sup>F]AlF-FAPI-74

2023-04-01 | Preprint
Contributors: Iris K. Lee; Estela Noguera-Ortega; Zebin Xiao; Leslie Todd; John Scholler; Decheng Song; Maria Liousia; Katheryn Lohith; Kexiang Xu; Kimberly J. Edwards et al.
Source: check_circle
Crossref

Supplementary Data from Monitoring Therapeutic Response to Anti-FAP CAR T Cells Using [<sup>18</sup>F]AlF-FAPI-74

2023-04-01 | Preprint
Contributors: Iris K. Lee; Estela Noguera-Ortega; Zebin Xiao; Leslie Todd; John Scholler; Decheng Song; Maria Liousia; Katheryn Lohith; Kexiang Xu; Kimberly J. Edwards et al.
Source: check_circle
Crossref

Supplementary Data from Monitoring Therapeutic Response to Anti-FAP CAR T Cells Using [<sup>18</sup>F]AlF-FAPI-74

2023-04-01 | Preprint
Contributors: Iris K. Lee; Estela Noguera-Ortega; Zebin Xiao; Leslie Todd; John Scholler; Decheng Song; Maria Liousia; Katheryn Lohith; Kexiang Xu; Kimberly J. Edwards et al.
Source: check_circle
Crossref

Supplementary Figure from Monitoring Therapeutic Response to Anti-FAP CAR T Cells Using [<sup>18</sup>F]AlF-FAPI-74

2023-04-01 | Preprint
Contributors: Iris K. Lee; Estela Noguera-Ortega; Zebin Xiao; Leslie Todd; John Scholler; Decheng Song; Maria Liousia; Katheryn Lohith; Kexiang Xu; Kimberly J. Edwards et al.
Source: check_circle
Crossref

Supplementary Figure from Monitoring Therapeutic Response to Anti-FAP CAR T Cells Using [<sup>18</sup>F]AlF-FAPI-74

2023-04-01 | Preprint
Contributors: Iris K. Lee; Estela Noguera-Ortega; Zebin Xiao; Leslie Todd; John Scholler; Decheng Song; Maria Liousia; Katheryn Lohith; Kexiang Xu; Kimberly J. Edwards et al.
Source: check_circle
Crossref

Mycobacterial surface characters remodeled by growth conditions drive different tumor-infiltrating cells and systemic IFN-γ/IL-17 release in bladder cancer treatment

OncoImmunology
2022-12-31 | Journal article
Contributors: Sandra Guallar-Garrido; Víctor Campo-Pérez; Míriam Pérez-Trujillo; Cecilia Cabrera; Jordi Senserrich; Alejandro Sánchez-Chardi; Rosa Maria Rabanal; Elisabet Gómez-Mora; Estela Noguera-Ortega; Marina Luquin et al.
Source: check_circle
Crossref

Monitoring Therapeutic Response to Anti-FAP CAR T Cells Using [18F]AlF-FAPI-74

Clinical Cancer Research
2022-12-15 | Journal article
Contributors: Iris K. Lee; Estela Noguera-Ortega; Zebin Xiao; Leslie Todd; John Scholler; Decheng Song; Maria Liousia; Katheryn Lohith; Kexiang Xu; Kimberly J. Edwards et al.
Source: check_circle
Crossref

PPT1 inhibition enhances the antitumor activity of anti–PD-1 antibody in melanoma

JCI Insight
2020-09-03 | Journal article
Contributors: Gaurav Sharma; Rani Ojha; Estela Noguera-Ortega; Vito W. Rebecca; John Attanasio; Shujing Liu; Shengfu Piao; Jennifer J. Lee; Michael C. Nicastri; Sandra L. Harper et al.
Source: check_circle
Crossref

Mycobacteria-Based Vaccines as Immunotherapy for Non-urological Cancers

Cancers
2020-07-05 | Journal article
Contributors: Estela Noguera-Ortega; Sandra Guallar-Garrido; Esther Julián
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

CAR T Cells for Solid Tumors: New Strategies for Finding, Infiltrating, and Surviving in the Tumor Microenvironment

Frontiers in Immunology
2019-02-05 | Journal article
Part of ISSN: 1664-3224
Source: Self-asserted source
Estela Noguera-Ortega

ER Translocation of the MAPK Pathway Drives Therapy Resistance in BRAF-Mutant Melanoma.

Cancer discovery
2018-12-18 | Journal article
Source: Self-asserted source
Estela Noguera-Ortega

PPT1 Promotes Tumor Growth and Is the Molecular Target of Chloroquine Derivatives in Cancer.

Cancer discovery
2018-11-15 | Journal article
Source: Self-asserted source
Estela Noguera-Ortega

Intravesical Mycobacterium brumae triggers both local and systemic immunotherapeutic responses against bladder cancer in mice

Scientific Reports
2018-10-10 | Journal article
Part of ISSN: 2045-2322
Contributors: Estela Noguera-Ortega; Rosa M. Rabanal; Elisabet Gómez-Mora; Cecilia Cabrera; Marina Luquin; Esther Julián
Source: Self-asserted source
Estela Noguera-Ortega via Crossref Metadata Search
grade
Preferred source (of 2)‎

Mycobacteria-Derived Agents for the Treatment of Urological and Renal Cancers

Mycobacterium - Research and Development
2018-06-20 | Book chapter
Part of ISBN: 9781789232103
Part of ISBN: 9781789232110
Source: Self-asserted source
Estela Noguera-Ortega
grade
Preferred source (of 2)‎

Autophagy in the Tumor or in the Host: Which Plays a Greater Supportive Role?

Cancer discovery
2018-03 | Journal article
Contributors: Noguera-Ortega E; Amaravadi RK
Source: Self-asserted source
Estela Noguera-Ortega via Europe PubMed Central

Mycobacteria Clumping Increase Their Capacity to Damage Macrophages.

Frontiers in microbiology
2016 | Journal article
Contributors: Brambilla C; Llorens-Fons M; Julián E; Noguera-Ortega E; Tomàs-Martínez C; Pérez-Trujillo M; Byrd TF; Alcaide F; Luquin M
Source: Self-asserted source
Estela Noguera-Ortega via Europe PubMed Central

Mycobacteria emulsified in olive oil-in-water trigger a robust immune response in bladder cancer treatment

Scientific Reports
2016-06-06 | Journal article
Part of ISSN: 2045-2322
Contributors: Estela Noguera-Ortega; Núria Blanco-Cabra; Rosa Maria Rabanal; Alejandro Sánchez-Chardi; Mónica Roldán; Sandra Guallar-Garrido; Eduard Torrents; Marina Luquin; Esther Julián
Source: Self-asserted source
Estela Noguera-Ortega via Crossref Metadata Search

Nonpathogenic Mycobacterium brumae Inhibits Bladder Cancer Growth In Vitro, Ex Vivo, and In Vivo

European Urology Focus
2015 | Journal article
Source: Self-asserted source
Estela Noguera-Ortega
grade
Preferred source (of 2)‎

γ-Irradiated mycobacteria enhance survival in bladder tumor-bearing mice although they are less efficacious than live mycobacteria.

2015-07 | Journal article
Contributors: Noguera-Ortega E; Rabanal RM; Secanella-Fandos S; Torrents E; Luquin M; Julián E
Source: Self-asserted source
Estela Noguera-Ortega via Europe PubMed Central

Killed but Metabolically Active Mycobacterium bovis bacillus Calmette-Guerin Retains the Antitumor Ability of Live bacillus Calmette-Guerin

Journal of Urology
2014 | Journal article
DOI:

10.1016/j.juro.2013.12.002

Contributors: Secanella-Fandos, Silvia; Noguera-Ortega, Estela; Olivares, Francesc; Luquin, Marina; Julian, Esther
Source: Self-asserted source
Estela Noguera-Ortega via ResearcherID

Peer review (32 reviews for 6 publications/grants)

Review activity for Biology. (1)
Review activity for Biomolecules. (13)
Review activity for Cancers. (14)
Review activity for JoVE. (1)
Review activity for Pathogens. (1)
Review activity for Pharmaceutics. (2)