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Works (5)

Substrate-specific effects point to the important role of Y361 as part of the YER motif in closing the binding pocket of OCT1

Journal of Biological Chemistry
2025-02 | Journal article
Contributors: Sarah Römer; Erika Lazzarin; Anna Neumann; Erik Lindemann; Marleen J. Meyer-Tönnies; Thomas Stockner; Mladen V. Tzvetkov
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Interaction of GAT1 with sodium ions: from efficient recruitment to stabilisation of substrate and conformation

2024-10-02 | Preprint
Contributors: Erika Lazzarin; Ralph Gradisch; Sophie MC Skopec; Leticia Alves da Silva; Chiara Sebastianelli-Schoditsch; Dániel Szöllősi; Julian Maier; Sonja Sucic; Marko Roblek; Baruch I Kanner et al.
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Unveiling the crucial role of betaine: Modulation of GABA homeostasis via SLC6A1 transporter (GAT1)

2024-05-01 | Preprint
Contributors: Manan Bhatt; Erika Lazzarin; Ana Sofia Alberto-Silva; Guido Domingo; Rocco Zerlotti; Ralph Gradisch; Andre Bazzone; Harald H. Sitte; Thomas Stockner; Elena Bossi
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Ligand coupling mechanism of the human serotonin transporter differentiates substrates from inhibitors

Nature Communications
2024-01-10 | Journal article
Contributors: Ralph Gradisch; Katharina Schlögl; Erika Lazzarin; Marco Niello; Julian Maier; Felix P. Mayer; Leticia Alves da Silva; Sophie M. C. Skopec; Randy D. Blakely; Harald H. Sitte et al.
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Interaction of GAT1 with sodium ions: from efficient recruitment to stabilisation of substrate and conformation

2023-10-13 | Preprint
Contributors: Erika Lazzarin; Ralph Gradisch; Sophie M.C. Skopec; Leticia Alves da Silva; Chiara Sebastianelli-Schoditsch; Dániel Szöllősi; Julian Maier; Sonja Sucic; Marko Roblek; Baruch I. Kanner et al.
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Crossref