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Scopus Author ID: 25825436400
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Employment (4)

Jagiellonian University: Krakow, PL

2020 to present (Department of Evolutionary Immunology)
Employment
Source: Self-asserted source
Tomasz Prajsnar

University of Sheffield Medical School: Sheffield, GB

2017-05 to 2019-12 | Post-doctoral Researcher (Department of Infection, Immunity and Cardiovascular Disease)
Employment
Source: Self-asserted source
Tomasz Prajsnar

Leiden University: Leiden, NL

2015-02 to 2017-05 | Marie Curie Postdoctoral Fellow (Institute of Biology Leiden )
Employment
Source: Self-asserted source
Tomasz Prajsnar

University of Sheffield: Sheffield, GB

2014-02 to 2015-02 | BIA Postdoctoral Fellow (Department of Molecular Biology and Biotechnology)
Employment
Source: Self-asserted source
Tomasz Prajsnar

Education and qualifications (2)

University of Sheffield Medical School: Sheffield, Sheffield, GB

2006-10 to 2010-02 | PhD (Department of Infection and Immunity)
Qualification
Source: Self-asserted source
Tomasz Prajsnar

Jagiellonian University: Krakow, PL

2001-10 to 2006-06 | MSc in Medical Biotechnology (Faculty of Biochemistry, Biophysics and Biotechnology)
Education
Source: Self-asserted source
Tomasz Prajsnar

Works (39)

Experimental evolution of Staphylococcus aureus in macrophages: dissection of a conditional adaptive trait promoting intracellular survival

mBio
2024 | Journal article
DOI: 10.1128/mbio.00346-24
EID:

2-s2.0-85196053200

Part of ISSN: 21507511 21612129
Contributors: Alves, J.; Vrieling, M.; Ring, N.; Yebra, G.; Pickering, A.; Prajsnar, T.K.; Renshaw, S.A.; Fitzgerald, J.R.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Pulses of Class I PI3kinase activity identify the release and recapture of prey from neutrophil phagosomes

bioRxiv
2024 | Other
DOI: 10.1101/2024.02.29.582694
EID:

2-s2.0-85188848312

Part of ISSN: 26928205
Contributors: Muir, C.F.; Reyes-Aldasoro, C.C.; Ellett, F.E.; Prajsnar, T.K.; Ho, Y.X.; Bernut, A.; Loynes, C.A.; Elworthy, S.; Bowden, K.A.; Cadbury, A.J. et al.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Activated PI3K delta syndrome 1 mutations cause neutrophilia in zebrafish larvae

DMM Disease Models and Mechanisms
2023 | Journal article
DOI: 10.1242/dmm.049841
EID:

2-s2.0-85150079683

Part of ISSN: 17548411 17548403
Contributors: Elworthy, S.; Rutherford, H.A.; Prajsnar, T.K.; Hamilton, N.M.; Vogt, K.; Renshaw, S.A.; Condliffe, A.M.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

MCPIP1 functions as a safeguard of early embryonic development

Scientific Reports
2023 | Journal article
DOI: 10.1038/s41598-023-44294-1
EID:

2-s2.0-85173531700

Part of ISSN: 20452322
Contributors: Lichawska-Cieslar, A.; Szukala, W.; Prajsnar, T.K.; Pooranachandran, N.; Kulecka, M.; Dabrowska, M.; Mikula, M.; Rakus, K.; Chadzinska, M.; Jura, J.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Phagosomal Acidification Is Required to Kill Streptococcus pneumoniae in a Zebrafish Model

Cellular Microbiology
2022-06-09 | Journal article
DOI: 10.1155/2022/9429516
Part of ISSN: 1462-5822
Part of ISSN: 1462-5814
Source: Self-asserted source
Tomasz Prajsnar
grade
Preferred source (of 2)‎

Dram1 confers resistance to Salmonella infection

bioRxiv
2021 | Other
DOI: 10.1101/2021.03.21.436194
EID:

2-s2.0-85105407511

Part of ISSN: 26928205
Contributors: Masud, S.; Zhang, R.; Prajsnar, T.K.; Meijer, A.H.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)<sup>1</sup>

Autophagy
2021 | Journal article
DOI: 10.1080/15548627.2020.1797280
EID:

2-s2.0-85102619204

Part of ISSN: 15548635 15548627
Contributors: Klionsky, D.J.; Abdel-Aziz, A.K.; Abdelfatah, S.; Abdellatif, M.; Abdoli, A.; Abel, S.; Abeliovich, H.; Abildgaard, M.H.; Abudu, Y.P.; Acevedo-Arozena, A. et al.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Human-specific staphylococcal virulence factors enhance pathogenicity in a humanised zebrafish C5a receptor model

Journal of cell science
2021 | Journal article
DOI: 10.1242/jcs.252205
EID:

2-s2.0-85102605726

Part of ISSN: 14779137
Contributors: Buchan, K.D.; van Gent, M.; Prajsnar, T.K.; Ogryzko, N.V.; de Jong, N.W.M.; Kolata, J.; Foster, S.J.; van Strijp, J.A.G.; Renshaw, S.A.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Neutrophils use selective autophagy receptor Sqstm1/p62 to target Staphylococcus aureus for degradation in vivo in zebrafish

Autophagy
2021 | Journal article
DOI: 10.1080/15548627.2020.1765521
EID:

2-s2.0-85087184995

Part of ISSN: 15548635 15548627
Contributors: Gibson, J.F.; Prajsnar, T.K.; Hill, C.J.; Tooke, A.K.; Serba, J.J.; Tonge, R.D.; Foster, S.J.; Grierson, A.J.; Ingham, P.W.; Renshaw, S.A. et al.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

The autophagic response to Staphylococcus aureus provides an intracellular niche in neutrophils

Autophagy
2021 | Journal article
DOI: 10.1080/15548627.2020.1739443
EID:

2-s2.0-85081745871

Part of ISSN: 15548635 15548627
Contributors: Prajsnar, T.K.; Serba, J.J.; Dekker, B.M.; Gibson, J.F.; Masud, S.; Fleming, A.; Johnston, S.A.; Renshaw, S.A.; Meijer, A.H.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

The role of galanin during bacterial infection in larval zebrafish

Cells
2021 | Journal article
DOI: 10.3390/cells10082011
EID:

2-s2.0-85115042521

Part of ISSN: 20734409
Contributors: Nowik, N.; Prajsnar, T.K.; Przyborowska, A.; Rakus, K.; Sienkiewicz, W.; Spaink, H.P.; Podlasz, P.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Tilapia Lake Virus-Induced Neuroinflammation in Zebrafish: Microglia Activation and Sickness Behavior

Frontiers in Immunology
2021 | Journal article
DOI: 10.3389/fimmu.2021.760882
EID:

2-s2.0-85117900755

Part of ISSN: 16643224
Contributors: Mojzesz, M.; Widziolek, M.; Adamek, M.; Orzechowska, U.; Podlasz, P.; Prajsnar, T.K.; Pooranachandran, N.; Pecio, A.; Michalik, A.; Surachetpong, W. et al.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Human-specific staphylococcal virulence factors enhance pathogenicity in a humanised zebrafish C5a receptor model

bioRxiv
2020 | Other
DOI: 10.1101/2020.02.18.955021
EID:

2-s2.0-85102724146

Part of ISSN: 26928205
Contributors: Buchan, K.D.; van Gent, M.; Prajsnar, T.K.; Ogryzko, N.V.; de Jong, N.W.M.; Kolata, J.; Foster, S.J.; van Strijp, J.A.G.; Renshaw, S.A.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Polymersomes Eradicating Intracellular Bacteria

ACS Nano
2020 | Journal article
DOI: 10.1021/acsnano.0c01870
EID:

2-s2.0-85088581633

Part of ISSN: 1936086X 19360851
Contributors: Fenaroli, F.; Robertson, J.D.; Scarpa, E.; Gouveia, V.M.; Di Guglielmo, C.; De Pace, C.; Elks, P.M.; Poma, A.; Evangelopoulos, D.; Canseco, J.O. et al.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Macrophages target Salmonella by Lc3-associated phagocytosis in a systemic infection model

Autophagy
2019 | Journal article
DOI: 10.1080/15548627.2019.1569297
EID:

2-s2.0-85060626226
Contributors: Masud, S.; Prajsnar, T.K.; Torraca, V.; Lamers, G.E.M.; Benning, M.; Van Der Vaart, M.; Meijer, A.H.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Neutrophils use selective autophagy receptor p62 to target Staphylococcus aureus for degradation in the zebrafish model

bioRxiv
2019 | Other
DOI: 10.1101/604884
EID:

2-s2.0-85095643675

Part of ISSN: 26928205
Contributors: Gibson, J.F.; Prajsnar, T.K.; Serba, J.J.; Tonge, R.D.; Grierson, A.J.; Ingham, P.W.; Renshaw, S.A.; Johnston, S.A.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

The autophagic response to Staphylococcus aureus provides an intracellular niche in neutrophils

bioRxiv
2019 | Other
DOI: 10.1101/581223
EID:

2-s2.0-85095647189

Part of ISSN: 26928205
Contributors: Prajsnar, T.K.; Serba, J.J.; Dekker, B.M.; Gibson, J.F.; Masud, S.; Fleming, A.; Johnston, S.A.; Renshaw, S.A.; Meijer, A.H.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Rubicon-Dependent Lc3 Recruitment to Salmonella-Containing Phagosomes Is a Host Defense Mechanism Triggered Independently From Major Bacterial Virulence Factors.

Frontiers in Cellular and Infection Microbiology
2019-08-02 | Journal article
DOI: 10.3389/fcimb.2019.00279
PMID: 31428591
PMC: PMC6688089
Source: Self-asserted source
Tomasz Prajsnar
grade
Preferred source (of 2)‎

Decoration of the enterococcal polysaccharide antigen EPA is essential for virulence, cell surface charge and interaction with effectors of the innate immune system.

PLoS pathogens
2019-05-02 | Journal article
DOI: 10.1371/journal.ppat.1007730
PMID: 31048927
Source: Self-asserted source
Tomasz Prajsnar
grade
Preferred source (of 2)‎

A transgenic zebrafish line for in vivo visualisation of neutrophil myeloperoxidase.

PloS one
2019-04-19 | Journal article
DOI: 10.1371/journal.pone.0215592
PMID: 31002727
Source: Self-asserted source
Tomasz Prajsnar
grade
Preferred source (of 2)‎

A transgenic zebrafish line for in vivo visualisation of neutrophil myeloperoxidase

bioRxiv
2018 | Other
DOI: 10.1101/456541
EID:

2-s2.0-85095483284

Part of ISSN: 26928205
Contributors: Buchan, K.D.; Prajsnar, T.K.; Ogryzko, N.V.; de Jong, N.W.M.; van Gent, M.; Kolata, J.; Foster, S.J.; van Strijp, J.A.G.; Renshaw, S.A.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Construction and use of Staphylococcus aureus strains to study within-host infection dynamics

Methods in Molecular Biology
2018 | Book chapter
DOI: 10.1007/978-1-4939-7638-6_2
EID:

2-s2.0-85040694395

Part of ISSN: 10643745
Contributors: McVicker, G.; Prajsnar, T.K.; Foster, S.J.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Decoration of the enterococcal polysaccharide antigen EPA is essential for virulence, cell surface charge and resistance to innate immunity

bioRxiv
2018 | Other
DOI: 10.1101/479022
EID:

2-s2.0-85095649908

Part of ISSN: 26928205
Contributors: Smith, R.E.; Salamaga, B.; Szkuta, P.; Hajdamowicz, N.; Prajsnar, T.K.; Bulmer, G.; Fontaine, T.; Kołodziejczyk, J.; Herry, J.-M.; Hounslow, A. et al.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Human skin commensals augment Staphylococcus aureus pathogenesis

Nature Microbiology
2018 | Journal article
DOI: 10.1038/s41564-018-0198-3
EID:

2-s2.0-85050003557
Contributors: Boldock, E.; Surewaard, B.G.J.; Shamarina, D.; Na, M.; Fei, Y.; Ali, A.; Williams, A.; Pollitt, E.J.G.; Szkuta, P.; Morris, P. et al.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Use of larval zebrafish model to study within-host infection dynamics

Methods in Molecular Biology
2018 | Book chapter
DOI: 10.1007/978-1-4939-7638-6_14
EID:

2-s2.0-85040672946

Part of ISSN: 10643745
Contributors: Prajsnar, T.K.; McVicker, G.; Williams, A.; Renshaw, S.A.; Foster, S.J.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Bacterial size matters: Multiple mechanisms controlling septum cleavage and diplococcus formation are critical for the virulence of the opportunistic pathogen Enterococcus faecalis

PLoS Pathogens
2017 | Journal article
DOI: 10.1371/journal.ppat.1006526
EID:

2-s2.0-85026859312
Contributors: Salamaga, B.; Prajsnar, T.K.; Jareño-Martinez, A.; Willemse, J.; Bewley, M.A.; Chau, F.; Ben Belkacem, T.; Meijer, A.H.; Dockrell, D.H.; Renshaw, S.A. et al.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Fitness determinants of vancomycin-resistant Enterococcus faecium during growth in human serum

bioRxiv
2017 | Other
DOI: 10.1101/101329
EID:

2-s2.0-85095656132

Part of ISSN: 26928205
Contributors: Zhang, X.; Guzman Prieto, A.M.; de Maat, V.; Prajsnar, T.K.; Bayjanov, J.R.; de Been, M.; Rogers, M.R.C.; Bonten, M.J.M.; Mesnage, S.; Willems, R.J.L. et al.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

RNA-seq and Tn-seq reveal fitness determinants of vancomycin-resistant Enterococcus faecium during growth in human serum

BMC Genomics
2017 | Journal article
DOI: 10.1186/s12864-017-4299-9
EID:

2-s2.0-85034663285
Contributors: Zhang, X.; de Maat, V.; Guzmán Prieto, A.M.; Prajsnar, T.K.; Bayjanov, J.R.; de Been, M.; Rogers, M.R.C.; Bonten, M.J.M.; Mesnage, S.; Willems, R.J.L. et al.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Targeting mononuclear phagocytes for eradicating intracellular parasites

bioRxiv
2017 | Other
DOI: 10.1101/119297
EID:

2-s2.0-85095631013

Part of ISSN: 26928205
Contributors: Rizzello, L.; Robertson, J.D.; Elks, P.M.; Poma, A.; Daneshpour, N.; Prajsnar, T.K.; Evangelopoulos, D.; Canseco, J.O.; Yona, S.; Marriott, H.M. et al.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Intracellular Staphylococcus aureus eludes selective autophagy by activating a host cell kinase

Autophagy
2016 | Journal article
DOI: 10.1080/15548627.2016.1226732
EID:

2-s2.0-84990219083
Contributors: Neumann, Y.; Bruns, S.A.; Rohde, M.; Prajsnar, T.K.; Foster, S.J.; Schmitz, I.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Zebrafish as a new model to study effects of periodontal pathogens on cardiovascular diseases

Scientific Reports
2016 | Journal article
DOI: 10.1038/srep36023
EID:

2-s2.0-84992363477
Contributors: Widziolek, M.; Prajsnar, T.K.; Tazzyman, S.; Stafford, G.P.; Potempa, J.; Murdoch, C.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Existence of a colonizing Staphylococcus aureus strain isolated in diabetic foot ulcers

Diabetes
2015 | Journal article
DOI: 10.2337/db15-0031
EID:

2-s2.0-84964697346
Contributors: Messad, N.; Prajsnar, T.K.; Lina, G.; O'Callaghan, D.; Foster, S.J.; Renshaw, S.A.; Skaar, E.P.; Bes, M.; Dunyach-Remy, C.; Vandenesch, F. et al.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

A Spaetzle-like role for nerve growth factor β in vertebrate immunity to Staphylococcus aureus

Science
2014 | Journal article
DOI: 10.1126/science.1258705
EID:

2-s2.0-84909595112
Contributors: Hepburn, L.; Prajsnar, T.K.; Klapholz, C.; Moreno, P.; Loynes, C.A.; Ogryzko, N.V.; Brown, K.; Schiebler, M.; Hegyi, K.; Antrobus, R. et al.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Clonal Expansion during Staphylococcus aureus Infection Dynamics Reveals the Effect of Antibiotic Intervention

PLoS Pathogens
2014 | Journal article
DOI: 10.1371/journal.ppat.1003959
EID:

2-s2.0-84895730300
Contributors: McVicker, G.; Prajsnar, T.K.; Williams, A.; Wagner, N.L.; Boots, M.; Renshaw, S.A.; Foster, S.J.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Zebrafish as a novel vertebrate model to dissect enterococcal pathogenesis

Infection and Immunity
2013 | Journal article
DOI: 10.1128/IAI.00976-13
EID:

2-s2.0-84886778892
Contributors: Prajsnar, T.K.; Renshaw, S.A.; Ogryzko, N.V.; Foster, S.J.; Serror, P.; Mesnagea, S.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

A privileged intraphagocyte niche is responsible for disseminated infection of staphylococcus aureus in a zebrafish model

Cellular Microbiology
2012 | Journal article
DOI: 10.1111/j.1462-5822.2012.01826.x
EID:

2-s2.0-84866338541
Contributors: Prajsnar, T.K.; Hamilton, R.; Garcia-Lara, J.; Mcvicker, G.; Williams, A.; Boots, M.; Foster, S.J.; Renshaw, S.A.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

The Lysozyme-Induced Peptidoglycan N-Acetylglucosamine Deacetylase pgda (EF1843) Is Required for Enterococcus faecalis Virulence

Journal of Bacteriology
2012 | Journal article
DOI: 10.1128/JB.00981-12
EID:

2-s2.0-84869116802
Contributors: Benachour, A.; Ladjouzi, R.; Le Jeune, A.; Hébert, L.; Thorpe, S.; Courtin, P.; Chapot-Chartier, M.-P.; Prajsnar, T.K.; Foster, S.J.; Mesnage, S.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

A novel vertebrate model of Staphylococcus aureus infection reveals phagocyte-dependent resistance of zebrafish to non-host specialized pathogens

Cellular Microbiology
2008 | Journal article
DOI: 10.1111/j.1462-5822.2008.01213.x
EID:

2-s2.0-54049105321
Contributors: Prajsnar, T.K.; Cunliffe, V.T.; Foster, S.J.; Renshaw, S.A.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Identification and characterization of σ<sup>S</sup>, a novel component of the Staphylococcus aureus stress and virulence responses

PLoS ONE
2008 | Journal article
DOI: 10.1371/journal.pone.0003844
EID:

2-s2.0-57349134511
Contributors: Shaw, L.N.; Lindholm, C.; Prajsnar, T.K.; Miller, H.K.; Brown, M.C.; Golonka, E.; Stewart, G.C.; Tarkowski, A.; Potempa, J.
Source: Self-asserted source
Tomasz Prajsnar via Scopus - Elsevier

Peer review (1 review for 1 publication/grant)

Review activity for Nature communications (1)
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