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Employment (3)

University of Pennsylvania: Philadelphia, PA, US

Postdoctoral Researcher (DM-Infectious Diseases)
Employment
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University of Pennsylvania via ORCID Member Portal

University of Pennsylvania: Philadelphia, Pennsylvania, US

2022-07-01 to present | Senior Research Investigator (Department of Medicine)
Employment
Source: Self-asserted source
István Tombácz

University of Pennsylvania: Philadelphia, PA, US

2017-07-01 to 2022-06-30 | Postdoctoral Researcher (Department of Medicine)
Employment
Source: Self-asserted source
István Tombácz

Works (13)

CAR T cells produced in vivo to treat cardiac injury

Science
2022-01-07 | Journal article
Contributors: Joel G. Rurik; István Tombácz; Amir Yadegari; Pedro O. Méndez Fernández; Swapnil V. Shewale; Li Li; Toru Kimura; Ousamah Younoss Soliman; Tyler E. Papp; Ying K. Tam et al.
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Crossref

Highly efficient CD4+ T cell targeting and genetic recombination using engineered CD4+ cell-homing mRNA-LNPs.

Molecular therapy : the journal of the American Society of Gene Therapy
2021-06 | Journal article
Contributors: Tombácz I; Laczkó D; Shahnawaz H; Muramatsu H; Natesan A; Yadegari A; Papp TE; Alameh MG; Shuvaev V; Mui BL et al.
Source: Self-asserted source
István Tombácz via Europe PubMed Central

Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates.

NPJ vaccines
2021-04 | Journal article
Contributors: Saunders KO; Pardi N; Parks R; Santra S; Mu Z; Sutherland L; Scearce R; Barr M; Eaton A; Hernandez G et al.
Source: Self-asserted source
István Tombácz via Europe PubMed Central

Vaccination with Messenger RNA: A Promising Alternative to DNA Vaccination.

Methods in molecular biology (Clifton, N.J.)
2021-01 | Journal article
Contributors: Tombácz I; Weissman D; Pardi N
Source: Self-asserted source
István Tombácz via Europe PubMed Central

Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates

2020-12 | Preprint
Contributors: Saunders KO; Pardi N; Parks R; Santra S; Mu Z; Sutherland L; Scearce R; Barr M; Eaton A; Hernandez G et al.
Source: Self-asserted source
István Tombácz via Europe PubMed Central

A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice.

Immunity
2020-07 | Journal article
Contributors: Laczkó D; Hogan MJ; Toulmin SA; Hicks P; Lederer K; Gaudette BT; Castaño D; Amanat F; Muramatsu H; Oguin TH et al.
Source: Self-asserted source
István Tombácz via Europe PubMed Central

Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood-brain barrier.

Proceedings of the National Academy of Sciences of the United States of America
2020-01 | Journal article
Contributors: Marcos-Contreras OA; Greineder CF; Kiseleva RY; Parhiz H; Walsh LR; Zuluaga-Ramirez V; Myerson JW; Hood ED; Villa CH; Tombacz I et al.
Source: Self-asserted source
István Tombácz via Europe PubMed Central

Characterization of HIV-1 Nucleoside-Modified mRNA Vaccines in Rabbits and Rhesus Macaques.

Molecular therapy. Nucleic acids
2019-03 | Journal article
Contributors: Pardi N; LaBranche CC; Ferrari G; Cain DW; Tombácz I; Parks RJ; Muramatsu H; Mui BL; Tam YK; Karikó K et al.
Source: Self-asserted source
István Tombácz via Europe PubMed Central

Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses.

The Journal of experimental medicine
2018-05 | Journal article
Contributors: Pardi N; Hogan MJ; Naradikian MS; Parkhouse K; Cain DW; Jones L; Moody MA; Verkerke HP; Myles A; Willis E et al.
Source: Self-asserted source
István Tombácz via Europe PubMed Central

High Fcp1 phosphatase activity contributes to setting an intense transcription rate required in Drosophila nurse and follicular cells for egg production.

Gene
2012-08 | Journal article
Contributors: Juhász I; Villányi Z; Tombácz I; Boros IM
Source: Self-asserted source
István Tombácz via Europe PubMed Central

The RNA Pol II CTD phosphatase Fcp1 is essential for normal development in Drosophila melanogaster.

Gene
2009-07 | Journal article
Contributors: Tombácz I; Schauer T; Juhász I; Komonyi O; Boros I
Source: Self-asserted source
István Tombácz via Europe PubMed Central

GAL4 induces transcriptionally active puff in the absence of dSAGA- and ATAC-specific chromatin acetylation in the Drosophila melanogaster polytene chromosome.

Chromosoma
2009-05 | Journal article
Contributors: Ciurciu A; Tombácz I; Popescu C; Boros I
Source: Self-asserted source
István Tombácz via Europe PubMed Central

Misregulated RNA Pol II C-terminal domain phosphorylation results in apoptosis.

Cellular and molecular life sciences : CMLS
2009-03 | Journal article
Contributors: Schauer T; Tombácz I; Ciurciu A; Komonyi O; Boros IM
Source: Self-asserted source
István Tombácz via Europe PubMed Central

Peer review (1 review for 1 publication/grant)

Review activity for npj vaccines. (1)