Personal information

Activities

Employment (2)

Dana Farber Cancer Institute: Boston, MA, US

2009-06 to 2011-09 | Senior Research Technician/Lab Manager (Medical Oncology)
Employment
Source: Self-asserted source
Lear Brace

New England Biolabs Inc: Ipswich, MA, US

2004-02 to 2009-05 | Research Intern
Employment
Source: Self-asserted source
Lear Brace

Education and qualifications (2)

Harvard University: Cambridge, MA, US

2011-09-01 to 2016-10-20 | PhD (Genetics and Complex Diseases)
Education
Source: Self-asserted source
Lear Brace

Emmanuel College: Boston, MA, US

2005-09 to 2009-05 | Bachelors of Science (Chemistry and Biology)
Education
Source: Self-asserted source
Lear Brace

Works (10)

Dietary protein restriction reduces circulating VLDL triglyceride levels via CREBH-APOA5–dependent and –independent mechanisms

JCI Insight
2018-11-02 | Journal article
Contributors: J. Humberto Treviño-Villarreal; Justin S. Reynolds; Alexander Bartelt; P. Kent Langston; Michael R. MacArthur; Alessandro Arduini; Valeria Tosti; Nicola Veronese; Beatrice Bertozzi; Lear E. Brace et al.
Source: check_circle
Crossref

Increased oxidative phosphorylation in response to acute and chronic DNA damage

npj Aging and Mechanisms of Disease
2016-10-13 | Journal article
Contributors: Lear E Brace; Sarah C Vose; Kristopher Stanya; Rose M Gathungu; Vasant R Marur; Alban Longchamp; Humberto Treviño-Villarreal; Pedro Mejia; Dorathy Vargas; Karen Inouye et al.
Source: check_circle
Crossref

Endogenous hydrogen sulfide production is essential for dietary restriction benefits.

2015-01 | Journal article
Contributors: Hine C; Harputlugil E; Zhang Y; Ruckenstuhl C; Lee BC; Brace L; Longchamp A; Treviño-Villarreal JH; Mejia P; Ozaki CK et al.
Source: Self-asserted source
Lear Brace via Europe PubMed Central

Defective mitophagy in XPA via PARP-1 hyperactivation and NAD(+)/SIRT1 reduction.

2014-05 | Journal article
Contributors: Fang EF; Scheibye-Knudsen M; Brace LE; Kassahun H; SenGupta T; Nilsen H; Mitchell JR; Croteau DL; Bohr VA
Source: Self-asserted source
Lear Brace via Europe PubMed Central

Lifespan extension by dietary intervention in a mouse model of Cockayne syndrome uncouples early postnatal development from segmental progeria.

2013-12 | Journal article
Contributors: Brace LE; Vose SC; Vargas DF; Zhao S; Wang XP; Mitchell JR
Source: Self-asserted source
Lear Brace via Europe PubMed Central

Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion.

2011-09 | Journal article
Contributors: Bass AJ; Lawrence MS; Brace LE; Ramos AH; Drier Y; Cibulskis K; Sougnez C; Voet D; Saksena G; Sivachenko A et al.
Source: Self-asserted source
Lear Brace via Europe PubMed Central

Mutations in the DDR2 kinase gene identify a novel therapeutic target in squamous cell lung cancer.

2011-06 | Journal article
Contributors: Hammerman PS; Sos ML; Ramos AH; Xu C; Dutt A; Zhou W; Brace LE; Woods BA; Lin W; Zhang J et al.
Source: Self-asserted source
Lear Brace via Europe PubMed Central

The Deinococcus radiodurans Snf2 intein caught in the act: detection of the Class 3 intein signature Block F branched intermediate.

2010-08 | Journal article
Contributors: Brace LE; Southworth MW; Tori K; Cushing ML; Perler F
Source: Self-asserted source
Lear Brace via Europe PubMed Central

Splicing of the mycobacteriophage Bethlehem DnaB intein: identification of a new mechanistic class of inteins that contain an obligate block F nucleophile.

2010-01 | Journal article
Contributors: Tori K; Dassa B; Johnson MA; Southworth MW; Brace LE; Ishino Y; Pietrokovski S; Perler FB
Source: Self-asserted source
Lear Brace via Europe PubMed Central

NMR structure of a KlbA intein precursor fromMethanococcus jannaschii

Protein Science
2007-07 | Journal article
Contributors: Margaret A. Johnson; Maurice W. Southworth; Torsten Herrmann; Lear Brace; Francine B. Perler; Kurt Wüthrich
Source: Self-asserted source
Lear Brace via Crossref Metadata Search