Personal information

Activities

Employment (3)

University of Florida: Gainesville, FL, US

2018-08-16 to present | Assistant Professor (Department of Chemical Engineering)
Employment
Source: Self-asserted source
Piyush K. Jain

Massachusetts Institute of Technology: Cambridge, MA, US

2018-03-24 to 2018-08-15 | Research Scientist (Institute of Medical Engineering & Science)
Employment
Source: Self-asserted source
Piyush K. Jain

Massachusetts Institute of Technology: Cambridge, MA, US

2013-06-01 to 2018-03-23 | Postdoctoral Associate (Institute for Medical Engineering & Science)
Employment
Source: Self-asserted source
Piyush K. Jain

Education and qualifications (2)

University of Missouri Kansas City: Kansas City, MO, US

2006-08-23 to 2013-05-20 | PhD (Department of Pharmaceutical Sciences)
Education
Source: Self-asserted source
Piyush K. Jain

Dr Hari Singh Gour University: Sagar, Madhya Pradesh, IN

2002-08-01 to 2006-07-01 | Bachelors of Pharmacy (Department of Pharmaceutical Sciences)
Education
Source: Self-asserted source
Piyush K. Jain

Funding (11)

A rapid CRISPR-based self-testing platform for early detection of HIV

2024-01-19 to 2026-12-31 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, US)
GRANT_NUMBER: R61AI181016
Source: Self-asserted source
Piyush K. Jain via DimensionsWizard

Discovery and engineering of CRISPR/Cas systems

2022-09-01 to 2027-08-31 | Grant
National Institute of General Medical Sciences (Bethesda, Maryland, US)
GRANT_NUMBER:

R35GM147788

Source: check_circle
University of Florida
grade
Preferred source (of 2)‎

The Development of Novel RNA Dependent RNA Polymerases, Nucleases, and Transposases by Metagenomics and Protein Engineering

2022-09-01 to 2024-08-30 | Award
US Department of Agriculture Agricultural Research Service (Washington, N/A, US)
GRANT_NUMBER:

58-6066-2-044

Source: check_circle
University of Florida

Discovery and engineering of CRISPR/Cas systems

2022-09 to 2027-08 | Grant
National Institute of General Medical Sciences (Bethesda, Maryland, US)
GRANT_NUMBER: 1R35GM147788-01
Source: Self-asserted source
Piyush K. Jain

Relapsing malaria in Africa: mechanisms for persistence amid falciparum decline

2022-07-25 to 2023-06-30 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, Maryland, US)
GRANT_NUMBER:

R01AI165537

Source: check_circle
University of Florida

Rapid point-of-care detection of Hepatitis C viral RNA using multiplexed CRISPR/Cas platforms

2022-05-01 to 2025-04-30 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, US)
GRANT_NUMBER: R21AI168795
Source: Self-asserted source
Piyush K. Jain via DimensionsWizard
grade
Preferred source (of 2)‎

Rapid detection of Hepatitis C virus using CRISPR/Cas

2021-09-01 to 2024-08-31 | Grant
National Institute of Allergy and Infectious Diseases (Bethesda, US)
GRANT_NUMBER: R21AI156321
Source: Self-asserted source
Piyush K. Jain via DimensionsWizard
grade
Preferred source (of 2)‎

COVID-19: SICA Study: Seroepidemiological Insight into COVID-19 transmission in Africa

2021-08-31 to 2026-08-30 | Award
Centers for Disease Control and Prevention (Atlanta, Georgia, US)
GRANT_NUMBER:

U01GH002338

Source: check_circle
University of Florida

COVID-19: Development and validation of a CRISPR-based rapid and affordable kit for early diagnosis of COVID-19

2020-11-25 to 2022-01-31 | Contract
United States-India Science and Technology Endowment Fund (Gainesville, N/A, US)
GRANT_NUMBER:

USISTEF/COVID-I/247/2020

Source: check_circle
University of Florida

Development of HITI CRISPR gene therapy for dilated cardiomyopathy in a canine model

2020-09-01 to 2022-08-31 | Contract
Sarepta Therapeutics Inc (Cambridge, N/A, US)
GRANT_NUMBER:

AGR00018125 TO No. 3

Source: check_circle
University of Florida

Early Detection of Breast Cancer in the Urine using CRISPR

2020-07-01 to 2021-06-30 | Grant
FLORIDA BREAST CANCER FOUNDATION (Gainesville, N/A, US)
GRANT_NUMBER:

AGR00018466

Source: check_circle
University of Florida

Works (46)

PAM-free diagnostics with diverse type V CRISPR-Cas systems

2024-10-23 | Preprint
Contributors: Piyush Jain; Santosh Rananaware; Katelyn Meister; Grace Shoemaker; Emma Vesco; Luke Samuel Sandoval; Jordan Lewis; August Bodin; Vedant Karalkar; Ian Lange et al.
Source: check_circle
Crossref

CRISPR-Mediated Gene Editing Tool Development for Patients with Usher Syndrome Type II

UF Journal of Undergraduate Research
2024-10-16 | Journal article | Author
Part of ISSN: 2638-0668
Contributors: Katerina; Kate Beerensson; Noah Rakestraw ; Piyush K. Jain
Source: check_circle
Florida Online Journals

CRISPR-Mediated Gene Editing Tool Development for Patients with Usher Syndrome Type II

UF Journal of Undergraduate Research
2024-10-11 | Journal article | Author
URI:

https://journals.flvc.org/UFJUR/article/view/135367

Part of ISSN: 2638-0668
Contributors: Katerina; Kate Beerensson; Noah Rakestraw ; Piyush K. Jain
Source: check_circle
Florida Online Journals

Harnessing noncanonical crRNA for highly efficient genome editing

Nature Communications
2024-05-07 | Journal article
Contributors: Guanhua Xun; Zhixin Zhu; Nilmani Singh; Jingxia Lu; Piyush K. Jain; Huimin Zhao
Source: check_circle
Crossref

Harnessing noncanonical crRNAs to improve functionality of Cas12a orthologs

Cell Reports
2024-02 | Journal article
Contributors: Long T. Nguyen; Nicolas C. Macaluso; Noah R. Rakestraw; Dylan R. Carman; Brianna L.M. Pizzano; Raymond C. Hautamaki; Santosh R. Rananaware; Isabel E. Roberts; Piyush K. Jain
Source: check_circle
Crossref

Programmable RNA detection with CRISPR-Cas12a

Nature Communications
2023-09-05 | Journal article
Contributors: Santosh R. Rananaware; Emma K. Vesco; Grace M. Shoemaker; Swapnil S. Anekar; Luke Samuel W. Sandoval; Katelyn S. Meister; Nicolas C. Macaluso; Long T. Nguyen; Piyush K. Jain
Source: check_circle
Crossref

CRISPR-based diagnostics detects invasive insect pests

bioRxiv
2023-05-18 | Journal article
Contributors: Pathour R. Shashank; Brandon M. Parker; Santosh R. Rananaware; David Plotkin; Christian Couch; Lilia G. Yang; Long T. Nguyen; N. R. Prasannakumar; W. Evan Braswell; Piyush K. Jain et al.
Source: check_circle
Dimensions

Engineering highly thermostable Cas12b via de novo structural analyses for one-pot detection of nucleic acids

Cell Reports Medicine
2023-05-08 | Journal article
Contributors: Long T. Nguyen; Santosh R. Rananaware; Lilia G. Yang; Nicolas C. Macaluso; Julio E. Ocana-Ortiz; Katelyn S. Meister; Brianna L.M. Pizzano; Luke Samuel W. Sandoval; Raymond C. Hautamaki; Zoe R. Fang et al.
Source: check_circle
Dimensions

Programmable RNA detection with CRISPR-Cas12a

2023-01-30 | Preprint
Contributors: Santosh R. Rananaware; Emma K. Vesco; Grace M. Shoemaker; Swapnil S. Anekar; Luke Samuel W. Sandoval; Katelyn S. Meister; Nicolas C. Macaluso; Long T. Nguyen; Piyush K. Jain
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

A Thermostable Cas12b from <i>Brevibacillus</i> Leverages One-Pot Discrimination of SARS-CoV-2 Variants of Concern

SSRN Electronic Journal
2022 | Journal article
Contributors: Long T. Nguyen; Nicolas C. Macaluso; Brianna L.M. Pizzano; Melanie N. Cash; Jan Spacek; Jan Karasek; Rhoel R. Dinglasan; Marco Salemi; Piyush K. Jain
Source: check_circle
Dimensions

Engineering Highly Thermostable Cas12b via de novo Structural Analyses for One-Pot Detection of Nucleic Acids

SSRN Electronic Journal
2022 | Journal article
Contributors: Long T. Nguyen; Santosh R. Rananaware; Lilia G. Yang; Nicolas C. Macaluso; Julio E. Ocana-Ortiz; Katelyn S. Meister; Brianna L.M. Pizzano; Luke Samuel W. Sandoval; Raymond C. Hautamaki; Zoe R. Fang et al.
Source: check_circle
Dimensions

A click chemistry amplified nanopore assay for ultrasensitive quantification of HIV-1 p24 antigen in clinical samples

Nature Communications
2022-11-11 | Journal article
Contributors: Xiaojun Wei; Xiaoqin Wang; Zehui Zhang; Yuanyuan Luo; Zixin Wang; Wen Xiong; Piyush K. Jain; John R. Monnier; Hui Wang; Tony Y. Hu et al.
Source: check_circle
Crossref

Engineering Highly Thermostable Cas12b via De Novo Structural Analyses for One-Pot Detection of Nucleic Acids

medRxiv
2022-10-04 | Journal article
Contributors: Long T. Nguyen; Santosh R. Rananaware; Lilia G. Yang; Nicolas C. Macaluso; Julio E. Ocana-Ortiz; Katelyn S. Meister; Brianna L.M. Pizzano; Luke Samuel W. Sandoval; Raymond C. Hautamaki; Zoe R. Fang et al.
Source: check_circle
Dimensions

Ancestral origins are associated with SARS-CoV-2 susceptibility and protection in a Florida patient population

2022-03-31 | Preprint
Contributors: Yiran Shen; Bhuwan Khatri; Santosh Rananaware; Danmeng Li; David A. Ostrov; Piyush K Jain; Christopher J. Lessard; Cuong Q. Nguyen
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

A thermostable Cas12b from Brevibacillus leverages one-pot discrimination of SARS-CoV-2 variants of concern

EBioMedicine
2022-03-13 | Journal article
Contributors: Long T. Nguyen; Nicolas C. Macaluso; Brianna L.M. Pizzano; Melanie N. Cash; Jan Spacek; Jan Karasek; Megan R. Miller; John A. Lednicky; Rhoel R. Dinglasan; Marco Salemi et al.
Source: check_circle
Dimensions

Rapid SARS-CoV-2 diagnosis using disposable strips and a metal-oxide-semiconductor field-effect transistor platform

Journal of Vacuum Science & Technology B Nanotechnology and Microelectronics Materials Processing Measurement and Phenomena
2022-02-09 | Journal article
Contributors: Chan-Wen Chiu; Minghan Xian; Jenna L. Stephany; Xinyi Xia; Chao-Ching Chiang; Fan Ren; Cheng-Tse Tsai; Siang-Sin Shan; Yu-Te Liao; Josephine F. Esquivel-Upshaw et al.
Source: check_circle
Dimensions

Clinical validation of engineered CRISPR/Cas12a for rapid SARS-CoV-2 detection

Communications Medicine
2022-01-12 | Journal article
Contributors: Long T. Nguyen; Santosh R. Rananaware; Brianna L. M. Pizzano; Brandon T. Stone; Piyush K. Jain
Source: check_circle
Crossref
grade
Preferred source (of 4)‎

A Thermostable Cas12b from Brevibacillus Leverages One-pot Detection of SARS-CoV-2 Variants of Concern

2021-10-18 | Other
Contributors: Long T. Nguyen; Nicolas C. Macaluso; Brianna L.M. Pizzano; Melanie N. Cash; Jan Spacek; Jan Karasek; Rhoel R. Dinglasan; Marco Salemi; Piyush K. Jain
Source: check_circle
Crossref

A Combinatorial Approach towards Adaptability of 22 Functional Cas12a Orthologs for Nucleic Acid Detection in Clinical Samples

2021-07-22 | Preprint
Contributors: Long T. Nguyen; Nicolas C. Macaluso; Piyush K. Jain
Source: check_circle
Crossref

Identification of risk and protective human leukocyte antigens in COVID-19 using genotyping and structural modeling

[]
2021-05-08 | Preprint
Source: Self-asserted source
Piyush K. Jain

CRISPR-ENHANCE: An enhanced nucleic acid detection platform using Cas12a

Methods
2021-02 | Journal article
Part of ISSN: 1046-2023
Source: Self-asserted source
Piyush K. Jain

Chapter 16 Mesoporous silica nanoparticles: synthesis, properties, and biomedical applications

2020 | Book chapter
Contributors: Marco A. Downing; Piyush K. Jain
Source: check_circle
Dimensions

Author Correction: Enhancement of trans-cleavage activity of Cas12a with engineered crRNA enables amplified nucleic acid detection

Nature Communications
2020-11-24 | Journal article
Contributors: Long T. Nguyen; Brianna M. Smith; Piyush K. Jain
Source: check_circle
Dimensions

Enhancement of trans-cleavage activity of Cas12a with engineered crRNA enables amplified nucleic acid detection

2020-04-14 | Preprint
Contributors: Long T. Nguyen; Brianna M. Smith; Piyush K. Jain
Source: check_circle
Crossref
grade
Preferred source (of 3)‎

Mesoporous silica nanoparticles: Synthesis, properties, and biomedical applications

Nanoparticles for Biomedical Applications: Fundamental Concepts, Biological Interactions and Clinical Applications
2019 | Book chapter
EID:

2-s2.0-85093482087

Contributors: Downing, M.A.; Jain, P.K.
Source: Self-asserted source
Piyush K. Jain via Scopus - Elsevier

Non-viral delivery of CRISPR/Cas9 complex using CRISPR-GPS nanocomplexes

Nanoscale
2019 | Journal article
Contributors: Piyush K. Jain; Justin H. Lo; Santosh Rananaware; Marco Downing; Apekshya Panda; Michelle Tai; Srivatsan Raghavan; Heather E. Fleming; Sangeeta N. Bhatia
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Photocleavable drug conjugates

2018-12-25 | Patent
Source: Self-asserted source
Piyush K. Jain

Front Cover: The ULTIMATE Reagent: A Universal Photocleavable and Clickable Reagent for the Regiospecific and Reversible End Labeling of Any Nucleic Acid (ChemBioChem 12/2018)

ChemBioChem
2018-06-18 | Journal article
Contributors: Piyush K. Jain; Simon H. Friedman
Source: check_circle
Crossref

The ULTIMATE Reagent: A Universal Photocleavable and Clickable Reagent for the Regiospecific and Reversible End Labeling of Any Nucleic Acid

ChemBioChem
2018-06-18 | Journal article
Contributors: Piyush K. Jain; Simon H. Friedman
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Methods and uses for remotely triggered protease activity measurements

2017-09-11 | Patent
Source: Self-asserted source
Piyush K. Jain

Macromol. Biosci. 8/2016

Macromolecular Bioscience
2016 | Journal article
EID:

2-s2.0-84982957788

Part of ISBN:

16165195 16165187

Contributors: Sarode, B.R.; Jain, P.K.; Friedman, S.H.
Source: Self-asserted source
Piyush K. Jain via Scopus - Elsevier

Polymerizing Insulin with Photocleavable Linkers to Make Light-Sensitive Macropolymer Depot Materials

Macromolecular Bioscience
2016 | Journal article
WOSUID:

WOS:000381047500003

Contributors: Sarode, B. R.; Jain, P. K.; Friedman, S. H.
Source: Self-asserted source
Piyush K. Jain via ResearcherID
grade
Preferred source (of 2)‎

Development of Light‐Activated CRISPR Using Guide RNAs with Photocleavable Protectors

Angewandte Chemie International Edition
2016-09-26 | Journal article
Contributors: Piyush K. Jain; Vyas Ramanan; Arnout G. Schepers; Nisha S. Dalvie; Apekshya Panda; Heather E. Fleming; Sangeeta N. Bhatia
Source: check_circle
Crossref
grade
Preferred source (of 4)‎

Photoactivated Spatiotemporally-Responsive Nanosensors of in Vivo Protease Activity

Acs Nano
2015 | Journal article
WOSUID:

WOS:000367280100020

Contributors: Dudani, J. S.; Jain, P. K.; Kwong, G. A.; Stevens, K. R.; Bhatia, S. N.
Source: Self-asserted source
Piyush K. Jain via ResearcherID
grade
Preferred source (of 2)‎

Patterning of cells through patterning of biology

Abstracts of Papers of the American Chemical Society
2014 | Journal article
WOSUID:

WOS:000349165101843

Contributors: Friedman, S. H.; Kala, A.; Jain, P. K.
Source: Self-asserted source
Piyush K. Jain via ResearcherID

Patterning of cells through patterning of biology

Molecular Biosystems
2014 | Journal article
WOSUID:

WOS:000337103600006

Contributors: Kala, A.; Jain, P. K.; Friedman, S. H.
Source: Self-asserted source
Piyush K. Jain via ResearcherID
grade
Preferred source (of 2)‎

The synthesis of tetra-modified RNA for the multidimensional control of gene expression via light-activated RNA interference

Nature Protocols
2014 | Journal article
WOSUID:

WOS:000329186400002

Contributors: Kala, A.; Jain, P. K.; Karunakaran, D.; Shah, S.; Friedman, S. H.
Source: Self-asserted source
Piyush K. Jain via ResearcherID
grade
Preferred source (of 2)‎

Construction of a Photoactivated Insulin Depot

Angewandte Chemie-International Edition
2013 | Journal article
WOSUID:

WOS:000313913300008

Contributors: Jain, P. K.; Karunakaran, D.; Friedman, S. H.
Source: Self-asserted source
Piyush K. Jain via ResearcherID
grade
Preferred source (of 2)‎

Construction of a Photoactivated Insulin Depot

Angewandte Chemie
2012-12-03 | Journal article
Contributors: Piyush K. Jain; Dipu Karunakaran; Simon H. Friedman
Source: check_circle
Dimensions

Patterning of Gene Expression Using New Photolabile Groups Applied to Light Activated RNAi

Journal of the American Chemical Society
2011 | Journal article
WOSUID:

WOS:000287553000015

Contributors: Jain, P. K.; Shah, S.; Friedman, S. H.
Source: Self-asserted source
Piyush K. Jain via ResearcherID
grade
Preferred source (of 2)‎

BIOL 43 - Optimization of light activated RNA interference using new photolabile groups

Abstracts of Papers of the American Chemical Society
2009 | Journal article
WOSUID:

WOS:000207861900759

Contributors: Friedman, Simon H.; Jain, Piyush K.; Shah, Samit
Source: Self-asserted source
Piyush K. Jain via ResearcherID

Light Activated RNA Interference Using Photo-cleavable siRNA

Journal of Biomolecular Structure &amp; Dynamics
2009 | Journal article
WOSUID:

WOS:000266300700050

Contributors: Shah, Samit; Jain, Piyush; Karunakaran, Dipu; Kala, Ashish; Rangarajan, Subhashree; Friedman, Simon H.
Source: Self-asserted source
Piyush K. Jain via ResearcherID

Light-activated RNA interference using double-stranded siRNA precursors modified using a remarkable regiospecificity of diazo-based photolabile groups

Nucleic Acids Research
2009 | Journal article
WOSUID:

WOS:000268331800037

Contributors: Shah, Samit; Jain, Piyush K.; Kala, Ashish; Karunakaran, Dipu; Friedman, Simon H.
Source: Self-asserted source
Piyush K. Jain via ResearcherID
grade
Preferred source (of 2)‎

CRISPR-Enhance Flourescence based Assay v1.0 v1

Other
Contributors: Piyush Jain; Long T Nguyen; Santosh Rananaware
Source: Self-asserted source
Piyush K. Jain via Crossref Metadata Search

CRISPR-Enhance Lateral Flow Assay v1

Other
Contributors: Piyush Jain; Long T Nguyen; Santosh Rananaware
Source: Self-asserted source
Piyush K. Jain via Crossref Metadata Search

CRISPR-Enhance Lateral Flow Assay v1.0 v1

Other
Contributors: Piyush Jain; Long T Nguyen; Santosh Rananaware
Source: Self-asserted source
Piyush K. Jain via Crossref Metadata Search

Peer review (30 reviews for 10 publications/grants)

Review activity for Chem. (1)
Review activity for Chemical communications. (17)
Review activity for Drug delivery and translational research. (1)
Review activity for Journal of materials chemistry. (1)
Review activity for Nature biotechnology. (1)
Review activity for Nature communications (2)
Review activity for Nature medicine. (1)
Review activity for Nucleic acids research. (1)
Review activity for Organic & biomolecular chemistry. (4)
Review activity for The CRISPR journal. (1)