Personal information

Cell Biology, Tissue Engineering, Regenerative Medicine, Glaucoma, Bone, Hydrogels, Organoids
United States

Activities

Employment (6)

SUNY Upstate Medical University: Syracuse, New York, US

2018-08-01 to present | Assistant Professor (Ophthalmology, Cell and Developmental Biology)
Employment
Source: Self-asserted source
Samuel Herberg

Wake Forest School of Medicine: NC, NC, US

2017-08-01 to 2018-07-31 | Sr Research Fellow (Wake Forest Institute for Regenerative Medicine)
Employment
Source: Self-asserted source
Samuel Herberg

Case Western Reserve University: Cleveland, OH, US

2014-07 to 2017-07 | NRSA F32 Postdoctoral Fellow (Biomedical Engineering)
Employment
Source: Self-asserted source
Samuel Herberg

Augusta University: Augusta, GA, US

2013-05 to 2014-06 | Research Associate (Cellular Biology and Anatomy)
Employment
Source: Self-asserted source
Samuel Herberg

Augusta University: Augusta, GA, US

2008-08 to 2013-05 | Graduate Research Assistant (Cellular Biology and Anatomy)
Employment
Source: Self-asserted source
Samuel Herberg

Scil Technology GmbH: Martinsried, Bayern, DE

2005 to 2008 | Manager Pharmaceutical Development (Pharmaceutical Development)
Employment
Source: Self-asserted source
Samuel Herberg

Education and qualifications (2)

Augusta University: Augusta, GA, US

2008 to 2013 | PhD Cellular Biology and Anatomy (Cellular Biology and Anatomy)
Education
Source: Self-asserted source
Samuel Herberg

Hochschule Darmstadt: Darmstadt, Hessen, DE

2001 to 2005 | BS Biotechnology Engineering (Chemical and Biotechnology Engineering)
Education
Source: Self-asserted source
Samuel Herberg

Funding (3)

The role of glaucomatous trabecular meshwork cues in driving Schlemm’s canal cell mechano-pathobiology

2024-07-01 to 2026-06-30 | Grant
BrightFocus Foundation (Clarksburg, US)
GRANT_NUMBER:

G2024006S

Source: check_circle
ProposalCentral

Role of cellular memory in glaucoma.

2022-09-30 to 2027-08-31 | Grant
National Eye Institute (Bethesda, US)
GRANT_NUMBER: R01EY034096
Source: Self-asserted source
Samuel Herberg via DimensionsWizard

Blockade of miR-29b-1-5p promotes MSC-mediated bone regeneration during aging

2014-08-01 to 2017-07-31 | Grant
National Institute of Dental and Craniofacial Research (n/a, US)
GRANT_NUMBER: grant.F32DE024712
Source: Self-asserted source
Samuel Herberg via DimensionsWizard

Works (50 of 54)

Items per page:
Page 1 of 2

TRPV4 overactivation enhances cellular contractility and drives ocular hypertension in TGFβ2 overexpressing eyes

2025-01-21 | Preprint
Contributors: Christopher N Rudzitis; Monika Lakk; Ayushi Singh; Sarah N Redmon; Denisa Kirdajova; Yun-Ting Tseng; Michael L De Ieso; W Daniel Stamer; Samuel Herberg; David Križaj
Source: check_circle
Crossref

TRPV4 overactivation enhances cellular contractility and drives ocular hypertension in TGFβ2 overexpressing eyes

2025-01-21 | Preprint
Contributors: Christopher N Rudzitis; Monika Lakk; Ayushi Singh; Sarah N Redmon; Denisa Kirdajova; Yun-Ting Tseng; Michael L De Ieso; W Daniel Stamer; Samuel Herberg; David Križaj
Source: check_circle
Crossref

The role of YAP/TAZ mechanosignaling in trabecular meshwork and Schlemm’s canal cell dysfunction

Vision Research
2024-11 | Journal article
Contributors: Rajanya Ghosh; Samuel Herberg
Source: check_circle
Crossref

TRPV4 overactivation enhances cellular contractility and drives ocular hypertension in TGFβ2 overexpressing eyes

2024-11-08 | Preprint
Contributors: Christopher N. Rudzitis; Monika Lakk; Ayushi Singh; Sarah N. Redmon; Denisa Kirdajova; Yun-Ting Tseng; Michael L. De Ieso; W. Daniel Stamer; Samuel Herberg; David Križaj
Source: check_circle
Crossref

ECM biomaterials for modeling of outflow cell biology in health and disease

Biomaterials and Biosystems
2024-03 | Journal article
Contributors: Souvik Ghosh; Samuel Herberg
Source: check_circle
Crossref

Targeting YAP/TAZ mechanosignaling to ameliorate stiffness-induced Schlemm’s canal cell pathobiology

American Journal of Physiology-Cell Physiology
2024-02-01 | Journal article
Contributors: Haiyan Li; Megan Kuhn; Ruth A. Kelly; Ayushi Singh; Kavipriya Kovai Palanivel; Izzy Salama; Michael L. De Ieso; W. Daniel Stamer; Preethi S. Ganapathy; Samuel Herberg
Source: check_circle
Crossref

Li et al_Source Data.xlsx

2023-11-21 | Journal article | Author
SOURCE-WORK-ID:

24584577

Contributors: Samuel Herberg
Source: check_circle
figshare

Li et al_Supplemental Material.pdf

2023-11-17 | Journal article | Author
SOURCE-WORK-ID:

24582357

Contributors: Samuel Herberg
Source: check_circle
figshare

Targeting YAP mechanosignaling to ameliorate stiffness-induced Schlemm’s canal cell pathobiology

2023-09-10 | Preprint
Contributors: Haiyan Li; Megan Kuhn; Ruth A. Kelly; Ayushi Singh; Kavipriya Kovai Palanivel; Izzy Salama; Michael L. De Ieso; W. Daniel Stamer; Preethi S. Ganapathy; Samuel Herberg
Source: check_circle
Crossref

Simvastatin Attenuates Glucocorticoid-Induced Human Trabecular Meshwork Cell Dysfunction via YAP/TAZ Inactivation

Current Eye Research
2023-08-03 | Journal article
Contributors: Hannah Yoo; Ayushi Singh; Haiyan Li; Ana N. Strat; Tyler Bagué; Preethi S. Ganapathy; Samuel Herberg
Source: check_circle
Crossref

YAP/TAZ inactivation with simvastatin attenuates glucocorticoid-induced human trabecular meshwork cell dysfunction

2022-09-28 | Preprint
Contributors: Hannah Yoo; Ayushi Singh; Haiyan Li; Ana N. Strat; Tyler Bagué; Preethi S. Ganapathy; Samuel Herberg
Source: check_circle
Crossref

TGFβ2 Regulates Human Trabecular Meshwork Cell Contractility via ERK and ROCK Pathways with Distinct Signaling Crosstalk Dependent on the Culture Substrate

Current Eye Research
2022-08-03 | Journal article
Contributors: Haiyan Li; Jessica L. Henty-Ridilla; Audrey M. Bernstein; Preethi S. Ganapathy; Samuel Herberg
Source: check_circle
Crossref

YAP/TAZ mediate TGFβ2-induced Schlemm’s canal cell dysfunction

2022-06-06 | Preprint
Contributors: Haiyan Li; Ayushi Singh; Kristin M. Perkumas; W. Daniel Stamer; Preethi S. Ganapathy; Samuel Herberg
Source: check_circle
Crossref

Effects of netarsudil-family Rho kinase inhibitors on human trabecular meshwork cell contractility and actin remodeling using a bioengineered ECM hydrogel

2022-05-19 | Preprint
Contributors: Tyler Bagué; Ayushi Singh; Rajanya Ghosh; Hannah Yoo; Curtis Kelly; Mitchell A. deLong; Casey C. Kopczynski; Samuel Herberg
Source: check_circle
Crossref

Engineering a 3D hydrogel system to study optic nerve head astrocyte morphology and behavior in response to glaucomatous insult

2022-01-11 | Preprint
Contributors: Ana N. Strat; Alexander Kirschner; Hannah Yoo; Ayushi Singh; Tyler Bagué; Haiyan Li; Samuel Herberg; Preethi S. Ganapathy
Source: check_circle
Crossref

Extracellular matrix stiffness and TGFβ2 regulate YAP/TAZ activity in human trabecular meshwork cells

2021-09-30 | Preprint
Contributors: Haiyan Li; VijayKrishna Raghunathan; W. Daniel Stamer; Preethi S. Ganapathy; Samuel Herberg
Source: check_circle
Crossref

TGFβ2 regulates human trabecular meshwork cell contractility via ERK and ROCK pathways with distinct signaling crosstalk dependent on the culture substrate

2021-07-01 | Other
Contributors: Haiyan Li; Jessica L. Henty-Ridilla; Preethi S. Ganapathy; Samuel Herberg
Source: check_circle
Crossref

Mechanosensitive channel inhibition attenuates TGFβ2-induced actin cytoskeletal remodeling and reactivity in mouse optic nerve head astrocytes

2021-06-05 | Other
Contributors: Alexander Kirschner; Ana N. Strat; John Yablonski; Tyler Bagué; Haiyan Li; Samuel Herberg; Preethi S. Ganapathy
Source: check_circle
Crossref

A tissue-engineered human trabecular meshwork hydrogel for advanced glaucoma disease modeling.

Experimental eye research
2021-01-28 | Journal article
Source: Self-asserted source
Samuel Herberg

Scaffold-free human mesenchymal stem cell construct geometry regulates long bone regeneration

Communications Biology
2021-01-19 | Journal article
Contributors: Samuel Herberg; Daniel Varghai; Daniel S. Alt; Phuong N. Dang; Honghyun Park; Yuxuan Cheng; Jung-Youn Shin; Anna D. Dikina; Joel D. Boerckel; Marsha W. Rolle et al.
Source: check_circle
Crossref

A tissue-engineered human trabecular meshwork hydrogel for advanced glaucoma disease modeling

2020-07-31 | Preprint
Contributors: Haiyan Li; Tyler Bagué; Alexander Kirschner; Robert W. Weisenthal; Alison E. Patteson; Nasim Annabi; W. Daniel Stamer; Preethi S. Ganapathy; Samuel Herberg
Source: check_circle
Crossref

Simulating the human colorectal cancer microenvironment in 3D tumor-stroma co-cultures in vitro and in vivo.

Scientific reports
2020-06-17 | Journal article
Source: Self-asserted source
Samuel Herberg

Pleural Effusion Aspirate for Use in 3D Lung Cancer Modeling and Chemotherapy Screening

ACS Biomaterials Science and Engineering
2019 | Journal article
EID:

2-s2.0-85063395184

Contributors: Mazzocchi, A.; Devarasetty, M.; Herberg, S.; Petty, W.J.; Marini, F.; Miller, L.; Kucera, G.; Dukes, D.K.; Ruiz, J.; Skardal, A. et al.
Source: Self-asserted source
Samuel Herberg via Scopus - Elsevier

What doesn't kill you makes you stranger: Dipeptidyl peptidase-4 (CD26) proteolysis differentially modulates the activity of many peptide hormones and cytokines generating novel cryptic bioactive ligands

Pharmacology and Therapeutics
2019 | Journal article
EID:

2-s2.0-85062148942

Contributors: Elmansi, A.M.; Awad, M.E.; Eisa, N.H.; Kondrikov, D.; Hussein, K.A.; Aguilar-Pérez, A.; Herberg, S.; Periyasamy-Thandavan, S.; Fulzele, S.; Hamrick, M.W. et al.
Source: Self-asserted source
Samuel Herberg via Scopus - Elsevier

Simulating the human tumor microenvironment in colorectal cancer organoids in vitro and in vivo

2019-11-01 | Other
Contributors: Mahesh Devarasetty; Anthony Dominijanni; Samuel Herberg; Ethan Shelkey; Aleksander Skardal; Shay Soker
Source: check_circle
Crossref

Scaffold-free human mesenchymal stem cell construct geometry regulates long bone regeneration

2019-09-30 | Other
Contributors: Samuel Herberg; Daniel Varghai; Daniel S. Alt; Phuong N. Dang; Honghyun Park; Yuxuan Cheng; Jung-Youn Shin; Anna D. Dikina; Joel D. Boerckel; Marsha W. Rolle et al.
Source: check_circle
Crossref

Deconstructed Microfluidic Bone Marrow On-A-Chip to Study Normal and Malignant Hemopoietic Cell-Niche Interactions.

Small (Weinheim an der Bergstrasse, Germany)
2019-08-29 | Journal article
Source: Self-asserted source
Samuel Herberg

Combinatorial morphogenetic and mechanical cues to mimic bone development for defect repair

Science Advances
2019-08-02 | Journal article
Contributors: S. Herberg; A. M. McDermott; P. N. Dang; D. S. Alt; R. Tang; J. H. Dawahare; D. Varghai; J.-Y. Shin; A. McMillan; A. D. Dikina et al.
Source: check_circle
Crossref

Recapitulating bone development through engineered mesenchymal condensations and mechanical cues for tissue regeneration

Science Translational Medicine
2019-06-05 | Journal article
Contributors: Anna M. McDermott; Samuel Herberg; Devon E. Mason; Joseph M. Collins; Hope B. Pearson; James H. Dawahare; Rui Tang; Amit N. Patwa; Mark W. Grinstaff; Daniel J. Kelly et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Selective serotonin re-uptake inhibitor sertraline inhibits bone healing in a calvarial defect model

International journal of oral science
2018 | Journal article
EID:

2-s2.0-85054441851

Contributors: Howie, R.N.; Herberg, S.; Durham, E.; Grey, Z.; Bennfors, G.; Elsalanty, M.; LaRue, A.C.; Hill, W.D.; Cray, J.J.
Source: Self-asserted source
Samuel Herberg via Scopus - Elsevier

RNA interfering molecule delivery from in situ forming biodegradable hydrogels for enhancement of bone formation in rat calvarial bone defects.

Acta biomaterialia
2018-06 | Journal article
Contributors: Nguyen MK; Jeon O; Dang PN; Huynh CT; Varghai D; Riazi H; McMillan A; Herberg S; Alsberg E
Source: Self-asserted source
Samuel Herberg via Europe PubMed Central
grade
Preferred source (of 2)‎

A Modular Strategy to Engineer Complex Tissues and Organs.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
2018-02 | Journal article
Contributors: Dikina AD; Alt DS; Herberg S; McMillan A; Strobel HA; Zheng Z; Cao M; Lai BP; Jeon O; Petsinger VI et al.
Source: Self-asserted source
Samuel Herberg via Europe PubMed Central
grade
Preferred source (of 2)‎

High-density human mesenchymal stem cell rings with spatiotemporally-controlled morphogen presentation as building blocks for engineering bone diaphyseal tissue.

Nanotheranostics
2018-02 | Journal article
Contributors: Herberg S; Varghai D; Cheng Y; Dikina AD; Dang PN; Rolle MW; Alsberg E
Source: Self-asserted source
Samuel Herberg via Europe PubMed Central

Endochondral Ossification in Critical-Sized Bone Defects via Readily Implantable Scaffold-Free Stem Cell Constructs.

Stem cells translational medicine
2017-07 | Journal article
Contributors: Dang PN; Herberg S; Varghai D; Riazi H; Varghai D; McMillan A; Awadallah A; Phillips LM; Jeon O; Nguyen MK et al.
Source: Self-asserted source
Samuel Herberg via Europe PubMed Central
grade
Preferred source (of 2)‎

Mesenchymal stem cell expression of SDF-1β synergizes with BMP-2 to augment cell-mediated healing of critical-sized mouse calvarial defects.

Journal of tissue engineering and regenerative medicine
2017-06 | Journal article
Contributors: Herberg S; Aguilar-Perez A; Howie RN; Kondrikova G; Periyasamy-Thandavan S; Elsalanty ME; Shi X; Hill WD; Cray JJ
Source: Self-asserted source
Samuel Herberg via Europe PubMed Central
grade
Preferred source (of 2)‎

Recapitulating bone development for tissue regeneration through engineered mesenchymal condensations and mechanical cues

2017-06 | Journal article
OTHER-ID:

PPR27704

Contributors: McDermott AM; Herberg S; Mason DE; Pearson HB; Dawahare JH; Collins JM; Grinstaff MW; Kelly DJ; Alsberg E; Boerckel JD
Source: Self-asserted source
Samuel Herberg via Europe PubMed Central

Controlled Dual Growth Factor Delivery From Microparticles Incorporated Within Human Bone Marrow-Derived Mesenchymal Stem Cell Aggregates for Enhanced Bone Tissue Engineering via Endochondral Ossification.

Stem cells translational medicine
2016-02 | Journal article
Contributors: Dang PN; Dwivedi N; Phillips LM; Yu X; Herberg S; Bowerman C; Solorio LD; Murphy WL; Alsberg E
Source: Self-asserted source
Samuel Herberg via Europe PubMed Central
grade
Preferred source (of 2)‎

The adipokine leptin mediates muscle- and liver-derived IGF-1 in aged mice.

Experimental gerontology
2015-10 | Journal article
Contributors: Hamrick MW; Dukes A; Arounleut P; Davis C; Periyasamy-Thandavan S; Mork S; Herberg S; Johnson MH; Isales CM; Hill WD et al.
Source: Self-asserted source
Samuel Herberg via Europe PubMed Central
grade
Preferred source (of 2)‎

Caloric restriction and the adipokine leptin alter the SDF-1 signaling axis in bone marrow and in bone marrow derived mesenchymal stem cells.

Molecular and cellular endocrinology
2015-07 | Journal article
Contributors: Periyasamy-Thandavan S; Herberg S; Arounleut P; Upadhyay S; Dukes A; Davis C; Johnson M; McGee-Lawrence M; Hamrick MW; Isales CM et al.
Source: Self-asserted source
Samuel Herberg via Europe PubMed Central
grade
Preferred source (of 2)‎

Mesenchymal stem cell expression of stromal cell-derived factor-1β augments bone formation in a model of local regenerative therapy.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society
2015-02 | Journal article
Contributors: Herberg S; Kondrikova G; Hussein KA; Johnson MH; Elsalanty ME; Shi X; Hamrick MW; Isales CM; Hill WD
Source: Self-asserted source
Samuel Herberg via Europe PubMed Central
grade
Preferred source (of 2)‎

Total body irradiation is permissive for mesenchymal stem cell-mediated new bone formation following local transplantation.

Tissue engineering. Part A
2014-12 | Journal article
Contributors: Herberg S; Kondrikova G; Hussein KA; Periyasamy-Thandavan S; Johnson MH; Elsalanty ME; Shi X; Hamrick MW; Isales CM; Hill WD
Source: Self-asserted source
Samuel Herberg via Europe PubMed Central
grade
Preferred source (of 2)‎

Inkjet-based biopatterning of SDF-1β augments BMP-2-induced repair of critical size calvarial bone defects in mice.

Bone
2014-10 | Journal article
Contributors: Herberg S; Kondrikova G; Periyasamy-Thandavan S; Howie RN; Elsalanty ME; Weiss L; Campbell P; Hill WD; Cray JJ
Source: Self-asserted source
Samuel Herberg via Europe PubMed Central
grade
Preferred source (of 2)‎

Low-dose bone morphogenetic protein-2/stromal cell-derived factor-1β cotherapy induces bone regeneration in critical-size rat calvarial defects.

Tissue engineering. Part A
2014-05 | Journal article
Contributors: Herberg S; Susin C; Pelaez M; Howie RN; Moreno de Freitas R; Lee J; Cray JJ; Johnson MH; Elsalanty ME; Hamrick MW et al.
Source: Self-asserted source
Samuel Herberg via Europe PubMed Central
grade
Preferred source (of 2)‎

Stromal cell-derived factor-1β mediates cell survival through enhancing autophagy in bone marrow-derived mesenchymal stem cells.

PloS one
2013 | Journal article
Contributors: Herberg S; Shi X; Johnson MH; Hamrick MW; Isales CM; Hill WD
Source: Self-asserted source
Samuel Herberg via Europe PubMed Central
grade
Preferred source (of 2)‎

Effects of the activin A-myostatin-follistatin system on aging bone and muscle progenitor cells.

Experimental gerontology
2013-02 | Journal article
Contributors: Bowser M; Herberg S; Arounleut P; Shi X; Fulzele S; Hill WD; Isales CM; Hamrick MW
Source: Self-asserted source
Samuel Herberg via Europe PubMed Central
grade
Preferred source (of 2)‎

Stromal cell-derived factor-1β potentiates bone morphogenetic protein-2-stimulated osteoinduction of genetically engineered bone marrow-derived mesenchymal stem cells in vitro.

Tissue engineering. Part A
2013-01 | Journal article
Contributors: Herberg S; Fulzele S; Yang N; Shi X; Hess M; Periyasamy-Thandavan S; Hamrick MW; Isales CM; Hill WD
Source: Self-asserted source
Samuel Herberg via Europe PubMed Central
grade
Preferred source (of 2)‎

Remote ischemic perconditioning is effective alone and in combination with intravenous tissue-type plasminogen activator in murine model of embolic stroke.

Stroke
2012-10 | Journal article
Contributors: Hoda MN; Siddiqui S; Herberg S; Periyasamy-Thandavan S; Bhatia K; Hafez SS; Johnson MH; Hill WD; Ergul A; Fagan SC et al.
Source: Self-asserted source
Samuel Herberg via Europe PubMed Central
grade
Preferred source (of 2)‎

Stability of human stromal-derived factor-1alpha (CXCL12alpha) after blood sampling.

Annals of clinical and laboratory science
2010 | Journal article
Contributors: Kirkpatrick B; Nguyen L; Kondrikova G; Herberg S; Hill WD
Source: Self-asserted source
Samuel Herberg via Europe PubMed Central

Stability of human stromal-derived factor-1α (CXCL12α) after blood sampling

Annals of Clinical and Laboratory Science
2010 | Journal article
EID:

2-s2.0-77955834773

Contributors: Kirkpatrick, B.; Nguyen, L.; Kondrikova, G.; Herberg, S.; Hill, W.D.
Source: Self-asserted source
Samuel Herberg via Scopus - Elsevier

The adipokine leptin increases skeletal muscle mass and significantly alters skeletal muscle miRNA expression profile in aged mice.

Biochemical and biophysical research communications
2010-09 | Journal article
Contributors: Hamrick MW; Herberg S; Arounleut P; He HZ; Shiver A; Qi RQ; Zhou L; Isales CM; Mi QS
Source: Self-asserted source
Samuel Herberg via Europe PubMed Central
grade
Preferred source (of 2)‎
Items per page:
Page 1 of 2

Peer review (15 reviews for 9 publications/grants)

Review activity for ACS biomaterials science & engineering. (1)
Review activity for Advanced science. (1)
Review activity for Experimental Eye Research. (7)
Review activity for Eye and vision. (1)
Review activity for Industrial & engineering chemistry research. (1)
Review activity for Journal of translational medicine. (1)
Review activity for Nature materials. (1)
Review activity for npj regenerative medicine. (1)
Review activity for Vision research. (1)