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Keywords

biotechnology, natural products, bioassays, genetic engineering, biochemistry

Countries

Spain

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Employment (10)

Fundación Instituto Canario de Investigación del Cáncer: La Laguna,, Tenerife, ES

2016-02-07 to present | Researcher responsible of project MACBIOBLUE (R&D)
Employment
Source: Self-asserted source
Rafael Zarate

Fundación Instituto Canario de Investigación del Cáncer: La Laguna, Tenerife, ES

2013 to 2016-05-31 | Manager of the research project Algabiomac (Research)
Employment
Source: Self-asserted source
Rafael Zarate

Fundación Instituto Canario de Investigación del Cáncer: La Laguna, Tenerife, ES

2013 to 2015 | Manager of the research project Algabiomac (Research)
Employment
Source: Self-asserted source
Rafael Zarate

Biotifarm Cluster (cluster of Biotechnol. and Pharma Industry of the Canary Islands) : La Laguna, Tenerife, ES

2012 to 2013 | Manager of Biotifarm (Management)
Employment
Source: Self-asserted source
Rafael Zarate

Fundación Instituto Canario de Investigación del Cáncer: La Laguna, Tenerife, ES

2010 to 2012 | Manager of the Foundation
Employment
Source: Self-asserted source
Rafael Zarate

Centro Atlántico del Medicamento S.A.: La Laguna, Tenerife, ES

2009 to 2010 | Director of R&D (Research and development)
Employment
Source: Self-asserted source
Rafael Zarate

Fundacion Instituto Canario de Investigación del Cancer: La Laguna, Tenerife, ES

2002 to 2002 | Researcher (Research and development)
Employment
Source: Self-asserted source
Rafael Zarate

Rijksuniversiteit Leiden: Leiden, NL

1998 to 2000 | Postdoctoral researcher ( Pharmacognosy, Leiden/Amsterdam Centre for Drug Research)
Employment
Source: Self-asserted source
Rafael Zarate

Universidad de Sevilla : Sevilla, Andalucia, ES

1995 to 1997 | Postdoctoral researcher (Dept of Plant Biology)
Employment
Source: Self-asserted source
Rafael Zarate

The University of Edinburgh: Edinburgh, Scotland, GB

1991 to 1994 | PhD student ( Dept of Botany)
Employment
Source: Self-asserted source
Rafael Zarate

Education and qualifications (4)

Universidad de La Laguna Facultad de Biología: La Laguna, Islas Canarias, ES

1989 to present | BSc
Education
Source: Self-asserted source
Rafael Zarate

Rijksuniversiteit Leiden: Leiden, NL

1998 to 2000 | Post doctoral fellow (Pharmacognosy, Leiden/Amsterdam Centre for Drug Research)
Education
Source: Self-asserted source
Rafael Zarate

Universidad de Sevilla: Sevilla, Andalucía, ES

1995 to 1997 | Postdoctoral fellow (Dept of Plant Biology)
Education
Source: Self-asserted source
Rafael Zarate

The University of Edinburgh: Edinburgh, Scotland, GB

1991 to 1994 | PhD (Dept of Botany)
Education
Source: Self-asserted source
Rafael Zarate

Funding (12)

Proyecto demostrativo y de transferencia tecnológica para ayudar a las empresas a desarrollar nuevos productos y procesos en el ámbito de la biotecnología azul de la Macaronesia

2016-10 to present | Contract
European Commission (PCT-MAC, BE)
URL: http://www.macbioblue.com
GRANT_NUMBER:

project MACBIOBLUE (MAC/1.1b/086)
Source: Self-asserted source
Rafael Zarate

Desarrollo de industrias biotecnológicas a partir de la explotación de macro y microalgas marinas de las regiones de la Macaronesia (y país tercer vecino)

2013 to 2015 | Grant
EU Programme PCT-MAC (Brussels, Canary Islands, BE)
URL: http://www.algabiomac.com
GRANT_NUMBER:

MAC/3/C217
Source: Self-asserted source
Rafael Zarate

Desarrollo de un producto antiparasitario natural para uso ganadero

2010 to 2012 | Grant
Gobierno de Canarias, Consejería Industria, Comercio y Turismo (Santa Cruz de Tenerife, Canary Islands, ES)
Source: Self-asserted source
Rafael Zarate

Contratación de personal investigador (I-3)

2010 to 2011 | Salary award
Ministerio de Educación, Cultura y Deporte (Madrid, Canary Islands, ES)
Source: Self-asserted source
Rafael Zarate

Desarrollo de industrias biotecnológicas y farmacéuticas basadas en el conocimiento y la biodiversidad macaronésica (Biopharmac)

2009 to 2011 | Grant
EU Program PCT-MAC (Brussels, Canary Islands, BE)
Source: Self-asserted source
Rafael Zarate

Nuevas entidades moleculares con actividad antitumoral, antihormonal y antiparasitaria

2009 to 2010 | Grant
Agencia Canaria de Investigación, Innovación y Sociedad de la Informacion (Santa Cruz de Tenerife, ES)
Source: Self-asserted source
Rafael Zarate

VIH (SIDA): búsqueda y caracterización de nuevas entidades moleculares con actividad anti-VIH para el desarrollo de nuevos fármacos antifusogénicos con potencial aplicabilidad en terapias alternativas en el SIDA

2008 to 2009 | Grant
Fundacion Canaria de Investigacion y Salud (Las Palmas de Gran Canaria, ES)
Source: Self-asserted source
Rafael Zarate

Biotecnología de la Síntesis de Ácidos Grasos: Interés en Medicina, Nutrición y Acuicultura

2007 to 2009 | Grant
Dirección General de Universidades, Gobierno de Canarias (Santa Cruz de Tenerife, ES)
Source: Self-asserted source
Rafael Zarate

Estrategia Multidisciplinar en el Diseño, Síntesis, Aislamiento, Producción Biotecnológica, Modelización, Transporte y Evaluación Farmacológica de Nuevas Entidades Moleculares con Actividad Antitumoral

2006 to 2009 | Grant
Ministerio de Educación y Ciencia (Madrid, ES)
Source: Self-asserted source
Rafael Zarate

Ensayo con oleiletanolamida y dos nuevas drogas para estudiar su mecanismo de acción en la obesidad

2005 to 2006 | Grant
Fundacion Canaria de Investigacion y Salud (Las Palmas de Gran Canaria, ES)
Source: Self-asserted source
Rafael Zarate

Nuevos Líderes en Terapia Antileishmania y Anticancerígenas: Productos Naturales y Sintéticos con Actividad Revertidora del Fenotipo de Multirresistencia a Fármacos y Antitumoral

2004 to 2006 | Grant
Ministerio de Educación y Ciencia (Madrid, ES)
Source: Self-asserted source
Rafael Zarate

Ingeniería del metabolismo secundario de las plantas medicinales: Atropa baetica, Maytenus amazonica y M. macrocarpa

2003 to 2008 | Grant
Ministerio de Educación y Ciencia (Madrid, ES)
Source: Self-asserted source
Rafael Zarate

Works (43)

Lipid characterization of 14 macroalgal species from Madeira Archipelago: implications for animal and human nutrition

Botanica Marina
2022-02-23 | Journal article
DOI: 10.1515/bot-2021-0024
Contributors: Ana Galindo; Diana B. Reis; Inés Rodríguez; José A. Pérez; Beatriz Abdul-Jalbar; Rafael Zárate; Nuno Nunes; Miguel A. A. Pinheiro de Carvalho; Nieves G. Acosta; Covadonga Rodríguez
Source: check_circle
Crossref

Pharmacological and Cosmeceutical Potential of Seaweed Beach-Casts of Macaronesia

Applied Sciences
2020-08-23 | Journal article
DOI: 10.3390/app10175831
Contributors: Rafael Zárate; Eduardo Portillo; Sílvia Teixidó; Miguel A. A. Pinheiro de Carvalho; Nuno Nunes; Sónia Ferraz; Ana M. L. Seca; Gonçalo P. Rosa; Maria Carmo Barreto
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Anticoccidial efficacy of Canary rue (Ruta pinnata) extracts against the caprine apicomplexan Eimeria ninakohlyakimovae

J. Anim. Sci.
2019 | Journal article
CIENCIAIUL: 2019.97:101–110
Source: Self-asserted source
Rafael Zarate

Significance of long chain polyunsaturated fatty acids in human health

Clinical and Translational Medicine
2017-12 | Journal article
DOI: 10.1186/s40169-017-0153-6
Contributors: Rafael Zárate; Nabil el Jaber‐Vazdekis; Noemi Tejera; José A. Pérez; Covadonga Rodríguez
Source: check_circle
Crossref

Healthy omega-3 enhancement in Echium acanthocarpum transformed hairy roots by overexpression of a 6-desaturase gene from Primula vialii

Scirea
2016 | Journal article
Source: Self-asserted source
Rafael Zarate

Importance of polyunsaturated fatty acid from marine algae. En: Omega-3 Fatty Acids – Keys to Nutritional Health. (Eds.) N. Hedge, A. Zanwar, SP Adekar

2016 | Book chapter
Source: Self-asserted source
Rafael Zarate

La producción de microalgas en la región Macaronésica ¿una realidad a corto o medio plazo?

2015-10 | Journal article
Source: Self-asserted source
Rafael Zarate

Micro and macroalgae from the Macaronesia. Search for bioactive compounds

Asociación de Investigación Cientifica del Atlantico
2015-10 | Journal article
Source: Self-asserted source
Rafael Zarate

Multi-development–HPTLC Method for Quantitation of Hyoscyamine, Scopolamine and their Biosynthetic Precursors in Selected Solanaceae Plants Grown in Natural Conditions and as In Vitro Cultures

Phytochem Anal
2014 | Journal article
Source: Self-asserted source
Rafael Zarate

Improvement of polyunsaturated fatty acid production in Echium acanthocarpum transformed hairy root cultures by application of different abiotic stress conditions

ISRN Biotechnology
2013 | Journal article
Source: Self-asserted source
Rafael Zarate

Metabolic Engineering of Plant Cellular Metabolism: Methodologies, Advances and Future Directions

Biotechnology for Medicinal Plants. Micropropagation and Improvement
2013 | Book chapter
Source: Self-asserted source
Rafael Zarate

Echium acanthocarpum hairy root cultures, a suitable system for polyunsaturated fatty acid research and production

BMC Biotechnology
2011 | Journal article
Source: Self-asserted source
Rafael Zarate

Plant Secondary Metabolism Engineering: Methods, Strategies, Advances, and Omics

2010 | Book chapter
Source: Self-asserted source
Rafael Zarate

The lupane-type triterpene 30-oxo-calenduladiol is a CCR5 antagonist with anti-HIV-1 and anti-chemotactic activities

Journal Biological Chemistry
2009 | Journal article
Source: Self-asserted source
Rafael Zarate

Biotechnology for the production of plant natural products

2008 | Book chapter
Source: Self-asserted source
Rafael Zarate

Cloning, characterization and analysis of expression profiles of a cDNA coding a hyoscyamine 6b-hydroxylase (H6H) from Atropa baetica Willk

Plant Physiol. Biochem
2008 | Journal article
Source: Self-asserted source
Rafael Zarate

Dichloromethane as solvent for lipid extraction, lipid classes and fatty acid assessment from samples of different nature

Journal Agricultural Food Chemistry
2008 | Journal article
Source: Self-asserted source
Rafael Zarate

Effects of Elicitors on Tropane Alkaloids and Gene Expression in Atropa baetica Transgenic Hairy Roots

Journal of Natural Products
2008 | Journal article
Source: Self-asserted source
Rafael Zarate

Seed germination and in vitro propagation of Maytenus canariensis through regeneration of adventitious shoots from axillary and apical buds

Biologia Plantarum
2008 | Journal article
Source: Self-asserted source
Rafael Zarate

Double domino Knoevenagel hetero Diels-Alder strategy towards bis-pyrano-1,4-benzoquinones

Tetrahedron
2007 | Journal article
Source: Self-asserted source
Rafael Zarate

Strategies for the genetic modification of the medicinal plant Catharanthus roseus (L.) G. Don

Phytochemistry Reviews
2007 | Journal article
Source: Self-asserted source
Rafael Zarate

Terpenoids from the medicinal plant Maytenus ilicifolia

Journal of Natural Products
2007 | Journal article
Source: Self-asserted source
Rafael Zarate

Studies on tropane alkaloid extraction employing two different volatile organic solvents, dichloromethane versus chloroform

Phytochemical Analysi
2006 | Journal article
Source: Self-asserted source
Rafael Zarate

Tailoring tropane alkaloid accumulation in transgenic Atropa baetica hairy roots by overexpressing the coding enzyme gene hyoscyamine 6β-hydroxylase (H6H)

Biotechnology Letters
2006 | Journal article
Source: Self-asserted source
Rafael Zarate

Expression of strictosidine β-D-glucosidase cDNA, involved in the monoterpene indole alkaloid pathway, from Catharanthus roseus in a transgenic suspension culture of Nicotiana tabacum

Plant Physiol. Biochemistry
2001 | Journal article
Source: Self-asserted source
Rafael Zarate

Terpenoid indole alkaloid profile changes in Catharanthus pusillus during development

Plant Science
2001 | Journal article
Source: Self-asserted source
Rafael Zarate

Genetic transformation via particle bombardment of Catharanthus roseus plants through adventitious organogenesis of buds

Biotechnology Letters
1999 | Journal article
Source: Self-asserted source
Rafael Zarate

Tropane alkaloid production by Agrobacterium rhizogenes transformed hairy root cultures of Atropa baetica Willk.

Plant Cell Reports
1999 | Journal article
Source: Self-asserted source
Rafael Zarate

Embryo rescue and development of Juniperus oxycedrus sbsp.oxycedrus and macrocarpa

Seed Science and Technology
1998 | Journal article
Source: Self-asserted source
Rafael Zarate

In vitro germplasm conservation of Atropa baetica by cold storage

Botanic Garden Micropropagation News
1998 | Journal article
Source: Self-asserted source
Rafael Zarate

Induction and development of adventitious shorts of Atropa baetica as a means of propagation

Euphytica
1997 | Journal article
Source: Self-asserted source
Rafael Zarate

Changes in the amount of [6]-gingerol and derivatives during a culture cycle of ginger, Zingiber officinale Rosc.

Plant Science
1996 | Journal article
Source: Self-asserted source
Rafael Zarate

Application of two rapid techniques of column chromatography to separate the pungent principles of ginger, Zingiber officinale Rosc

Journal of Chromatography
1992 | Journal article
Source: Self-asserted source
Rafael Zarate

Journal article
DOI:

10.1023/A:1002953929890
Source: Self-asserted source
Rafael Zarate

Changes in the amounts of [6]gingerol and derivatives during a culture cycle of ginger, Zingiber officinale

Journal article
DOI:

10.1016/S0168-9452(96)04512-8
Source: Self-asserted source
Rafael Zarate

Double Domino Knoevenagel Hetero Diels—Alder Strategy Towards Bis-pyrano-1,4-benzoquinones.

Journal article
DOI:

10.1002/chin.200731110
Source: Self-asserted source
Rafael Zarate

Echium acanthocarpum hairy root cultures, a suitable system for polyunsaturated fatty acid studies and production

Journal article
DOI:

10.1186/1472-6750-11-42
Source: Self-asserted source
Rafael Zarate

Production of pulchelin E in hairy roots, callus and suspension cultures of Rudbeckia hirta L.

Journal article
DOI:

10.1016/S0168-9452(02)00065-1
Source: Self-asserted source
Rafael Zarate

Strategies for the genetic modification of the medicinal plant Catharanthus roseus (L.) G. Don

Journal article
DOI:

10.1007/s11101-006-9020-6
Source: Self-asserted source
Rafael Zarate

Studies of the cellular localization of the phenolic pungent principle of ginger, Zingiber officinale Roscoe

Journal article
DOI:

10.1111/j.1469-8137.1994.tb03948.x
Source: Self-asserted source
Rafael Zarate

Tailoring Tropane Alkaloid Accumulation in Transgenic Hairy Roots of Atropa baetica by Over-expressing the Gene Encoding Hyoscyamine 6β-hydroxylase

Journal article
DOI:

10.1007/s10529-006-9085-8
Source: Self-asserted source
Rafael Zarate

Terpenoid indole alkaloid profile changes in Catharanthus pusillus during development

Journal article
DOI:

10.1016/S0168-9452(01)00340-5
Source: Self-asserted source
Rafael Zarate

Tropane Alkaloid Distribution in Atropa baetica Plants

Journal article
DOI:

10.1023/B:JOEC.0000006489.76006.cb
Source: Self-asserted source
Rafael Zarate

Peer review (3 reviews for 3 publications/grants)

Review activity for 3 biotech. (1)
Review activity for Foods. (1)
Review activity for Marine drugs. (1)
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