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Employment (2)

McMaster University: Hamilton, ON, CA

2017-01 to present | Research Scientist (Department of Pathology/Department of Medicine)
Employment
Source: Self-asserted source
Anna Dvorkin-Gheva

McMaster University: Hamilton, ON, CA

2015-01 to 2017-01 | Scientific Research Associate (Department of Pathology)
Employment
Source: Self-asserted source
Anna Dvorkin-Gheva

Education and qualifications (4)

McMaster University: Hamilton, ON, CA

2009-01 to 2015-01 | Post-doctoral studies (Department of Pathology)
Education
Source: Self-asserted source
Anna Dvorkin-Gheva

Tel Aviv University: Tel Aviv, IL

2009 | Ph.D. (Department of Zoology)
Education
Source: Self-asserted source
Anna Dvorkin-Gheva

Tel Aviv University: Tel Aviv, IL

2004 | M.Sc. (Department of Zoology)
Education
Source: Self-asserted source
Anna Dvorkin-Gheva

Tel Aviv University: Tel Aviv, IL

2001 | B.Sc
Education
Source: Self-asserted source
Anna Dvorkin-Gheva

Works (50)

NOX4 links metabolic regulation in pancreatic cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4.

Science advances
2021-05 | Journal article
Contributors: Jain P; Dvorkin-Gheva A; Mollen E; Malbeteau L; Xie M; Jessa F; Dhavarasa P; Chung S; Brown KR; Jang GH et al.
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Differential expression of sputum and serum autoantibodies in patients with chronic obstructive pulmonary disease.

American journal of physiology. Lung cellular and molecular physiology
2021-04 | Journal article
Contributors: Cass SP; Dvorkin-Gheva A; Yang Y; McGrath JJ; Thayaparan D; Xiao J; Wang F; Mukherjee M; Long F; Peng T et al.
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Mononuclear phagocytic system and fibrosis: back to the future?

The European respiratory journal
2021-03 | Journal article
Contributors: Ask K; Vierhout M; Dvorkin-Gheva A; Shi W
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

FK506-Binding Protein 13 Expression Is Upregulated in Interstitial Lung Disease and Correlated with Clinical Severity. A Potentially Protective Role.

American journal of respiratory cell and molecular biology
2021-02 | Journal article
Contributors: Tat V; Ayaub EA; Ayoub A; Vierhout M; Naiel S; Padwal MK; Abed S; Mekhael O; Tandon K; Revill SD et al.
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Virus-Intrinsic Differences and Heterogeneous IRF3 Activation Influence IFN-Independent Antiviral Protection.

iScience
2020-11 | Journal article
Contributors: Hare DN; Baid K; Dvorkin-Gheva A; Mossman KL
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

NOX4 links metabolic regulation in pancreatic cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4

2020-10 | Preprint
Contributors: Jain P; Dvorkin-Gheva A; Mollen E; Xie M; Jessa F; Dhavarasa P; Chung S; Brown KR; Jang GH; Notta F et al.
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Suboptimal treatment response to anti-IL-5 monoclonal antibodies in severe eosinophilic asthmatics with airway autoimmune phenomena.

The European respiratory journal
2020-10 | Journal article
Contributors: Mukherjee M; Forero DF; Tran S; Boulay ME; Bertrand M; Bhalla A; Cherukat J; Al-Hayyan H; Ayoub A; Revill SD et al.
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Gene expression and <i>in situ</i> protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue.

The European respiratory journal
2020-09 | Journal article
Contributors: Aguiar JA; Tremblay BJ; Mansfield MJ; Woody O; Lobb B; Banerjee A; Chandiramohan A; Tiessen N; Cao Q; Dvorkin-Gheva A et al.
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Antagonists of the serotonin receptor 5A target human breast tumor initiating cells.

BMC cancer
2020-08 | Journal article
Contributors: Gwynne WD; Shakeel MS; Girgis-Gabardo A; Kim KH; Ford E; Dvorkin-Gheva A; Aarts C; Isaac M; Al-Awar R; Hassell JA
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Wnt activation as a therapeutic strategy in medulloblastoma.

Nature communications
2020-08 | Journal article
Contributors: Manoranjan B; Venugopal C; Bakhshinyan D; Adile AA; Richards L; Kameda-Smith MM; Whitley O; Dvorkin-Gheva A; Subapanditha M; Savage N et al.
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

A Cross-Reactive Small Protein Binding Domain Provides a Model to Study Off-Tumor CAR-T Cell Toxicity.

Molecular therapy oncolytics
2020-04 | Journal article
Contributors: Hammill JA; Kwiecien JM; Dvorkin-Gheva A; Lau VWC; Baker C; Wu Y; Bezverbnaya K; Aarts C; Heslen CW; Denisova GF et al.
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue

2020-04 | Preprint
Contributors: Aguiar JA; Tremblay BJ; Mansfield MJ; Woody O; Lobb B; Banerjee A; Chandiramohan A; Tiessen N; Dvorkin-Gheva A; Revill S et al.
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

FK506-binding protein 13 expression is upregulated in interstitial lung disease and correlated with clinical severity: a potentially protective role

2019-12 | Preprint
Contributors: Tat V; Ayaub E; Ayoub A; Vierhout M; Naiel S; Padwal M; Abed S; Mekhael O; Tandon K; Revill S et al.
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Monoamine oxidase-A activity is required for clonal tumorsphere formation by human breast tumor cells.

Cellular & molecular biology letters
2019-11 | Journal article
Contributors: Gwynne WD; Shakeel MS; Wu J; Hallett RM; Girgis-Gabardo A; Dvorkin-Gheva A; Hassell JA
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Protein Misfolding and Endoplasmic Reticulum Stress in Chronic Lung Disease: Will Cell-Specific Targeting Be the Key to the Cure?

Chest
2019-11 | Journal article
Contributors: Naiel S; Tat V; Padwal M; Vierhout M; Mekhael O; Yousof T; Ayoub A; Abed S; Dvorkin-Gheva A; Ask K
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Transcriptomic and functional analyses of 3D placental extravillous trophoblast spheroids.

Scientific reports
2019-08 | Journal article
Contributors: Wong MK; Wahed M; Shawky SA; Dvorkin-Gheva A; Raha S
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Bmi1 regulates human glioblastoma stem cells through activation of differential gene networks in CD133+ brain tumor initiating cells.

Journal of neuro-oncology
2019-05 | Journal article
Contributors: Vora P; Seyfrid M; Venugopal C; Qazi MA; Salim S; Isserlin R; Subapanditha M; O'Farrell E; Mahendram S; Singh M et al.
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Intraductal Adaptation of the 4T1 Mouse Model of Breast Cancer Reveals Effects of the Epithelial Microenvironment on Tumor Progression and Metastasis.

Anticancer research
2019-05 | Journal article
Contributors: Atiya HI; Dvorkin-Gheva A; Hassell J; Patel S; Parker RL; Hartstone-Rose A; Hodge J; Fan D; Ramsdell AF
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Prostaglandin E<sub>2</sub> inhibits profibrotic function of human pulmonary fibroblasts by disrupting Ca<sup>2+</sup> signaling.

American journal of physiology. Lung cellular and molecular physiology
2019-02 | Journal article
Contributors: Mukherjee S; Sheng W; Michkov A; Sriarm K; Sun R; Dvorkin-Gheva A; Insel PA; Janssen LJ
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Sputum Antineutrophil Cytoplasmic Antibodies in Serum Antineutrophil Cytoplasmic Antibody-Negative Eosinophilic Granulomatosis with Polyangiitis.

American journal of respiratory and critical care medicine
2019-01 | Journal article
Contributors: Mukherjee M; Thomas SR; Radford K; Dvorkin-Gheva A; Davydchenko S; Kjarsgaard M; Svenningsen S; Almas S; Felix LC; Stearns J et al.
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

The impact of cigarette smoke exposure, COPD, or asthma status on ABC transporter gene expression in human airway epithelial cells.

Scientific reports
2019-01 | Journal article
Contributors: Aguiar JA; Tamminga A; Lobb B; Huff RD; Nguyen JP; Kim Y; Dvorkin-Gheva A; Stampfli MR; Doxey AC; Hirota JA
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

IL-6 mediates ER expansion during hyperpolarization of alternatively activated macrophages.

Immunology and cell biology
2018-11 | Journal article
Contributors: Ayaub EA; Tandon K; Padwal M; Imani J; Patel H; Dubey A; Mekhael O; Upagupta C; Ayoub A; Dvorkin-Gheva A et al.
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Induction of Autonomous Memory Alveolar Macrophages Requires T Cell Help and Is Critical to Trained Immunity.

Cell
2018-10 | Journal article
Contributors: Yao Y; Jeyanathan M; Haddadi S; Barra NG; Vaseghi-Shanjani M; Damjanovic D; Lai R; Afkhami S; Chen Y; Dvorkin-Gheva A et al.
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

The Overlap of Lung Tissue Transcriptome of Smoke Exposed Mice with Human Smoking and COPD.

Scientific reports
2018-08 | Journal article
Contributors: Obeidat M; Dvorkin-Gheva A; Li X; Bossé Y; Brandsma CA; Nickle DC; Hansbro PM; Faner R; Agusti A; Paré PD et al.
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

The impact of cigarette smoke exposure, and COPD or asthma status on ABC transporter gene expression in human airway epithelial cells

2018-07 | Preprint
Contributors: Aguiar JA; Tamminga A; Lobb B; Huff RD; Nguyen J; Kim Y; Dvorkin-Gheva A; Stampfli MR; Doxey AC; Hirota JA
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Identification of Drug Candidates to Suppress Cigarette Smoke-induced Inflammation via Connectivity Map Analyses.

American journal of respiratory cell and molecular biology
2018-06 | Journal article
Contributors: Vanderstocken G; Dvorkin-Gheva A; Shen P; Brandsma CA; Obeidat M; Bossé Y; Hassell JA; Stampfli MR
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Changes in gut microbiota during development of compulsive checking and locomotor sensitization induced by chronic treatment with the dopamine agonist quinpirole.

Behavioural pharmacology
2018-04 | Journal article
Contributors: Jung TD; Jung PS; Raveendran L; Farbod Y; Dvorkin-Gheva A; Sakic B; Surette MG; Szechtman H
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Transforming the prostatic tumor microenvironment with oncolytic virotherapy.

Oncoimmunology
2018-03 | Journal article
Contributors: Atherton MJ; Stephenson KB; Tzelepis F; Bakhshinyan D; Nikota JK; Son HH; Jirovec A; Lefebvre C; Dvorkin-Gheva A; Ashkar AA et al.
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

A Single TCF Transcription Factor, Regardless of Its Activation Capacity, Is Sufficient for Effective Trilineage Differentiation of ESCs.

Cell reports
2017-09 | Journal article
Contributors: Moreira S; Polena E; Gordon V; Abdulla S; Mahendram S; Cao J; Blais A; Wood GA; Dvorkin-Gheva A; Doble BW
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Customized Viral Immunotherapy for HPV-Associated Cancer.

Cancer immunology research
2017-09 | Journal article
Contributors: Atherton MJ; Stephenson KB; Pol J; Wang F; Lefebvre C; Stojdl DF; Nikota JK; Dvorkin-Gheva A; Nguyen A; Chen L et al.
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

The POZ-ZF transcription factor Znf131 is implicated as a regulator of Kaiso-mediated biological processes.

Biochemical and biophysical research communications
2017-09 | Journal article
Contributors: Robinson SC; Donaldson-Kabwe NS; Dvorkin-Gheva A; Longo J; He L; Daniel JM
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

CXCR3 Signaling Is Required for Restricted Homing of Parenteral Tuberculosis Vaccine-Induced T Cells to Both the Lung Parenchyma and Airway.

Journal of immunology (Baltimore, Md. : 1950)
2017-08 | Journal article
Contributors: Jeyanathan M; Afkhami S; Khera A; Mandur T; Damjanovic D; Yao Y; Lai R; Haddadi S; Dvorkin-Gheva A; Jordana M et al.
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Serotonergic system antagonists target breast tumor initiating cells and synergize with chemotherapy to shrink human breast tumor xenografts.

Oncotarget
2017-05 | Journal article
Contributors: Gwynne WD; Hallett RM; Girgis-Gabardo A; Bojovic B; Dvorkin-Gheva A; Aarts C; Dias K; Bane A; Hassell JA
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Kaiso depletion attenuates the growth and survival of triple negative breast cancer cells.

Cell death & disease
2017-03 | Journal article
Contributors: Bassey-Archibong BI; Rayner LG; Hercules SM; Aarts CW; Dvorkin-Gheva A; Bramson JL; Hassell JA; Daniel JM
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Claudin-Low Breast Cancer; Clinical & Pathological Characteristics.

PloS one
2017-01 | Journal article
Contributors: Dias K; Dvorkin-Gheva A; Hallett RM; Wu Y; Hassell J; Pond GR; Levine M; Whelan T; Bane AL
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Total particulate matter concentration skews cigarette smoke's gene expression profile.

ERJ open research
2016-10 | Journal article
Contributors: Dvorkin-Gheva A; Vanderstocken G; Yildirim AÖ; Brandsma CA; Obeidat M; Bossé Y; Hassell JA; Stampfli MR
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Serotonin transporter antagonists target tumor-initiating cells in a transgenic mouse model of breast cancer.

Oncotarget
2016-08 | Journal article
Contributors: Hallett RM; Girgis-Gabardo A; Gwynne WD; Giacomelli AO; Bisson JN; Jensen JE; Dvorkin-Gheva A; Hassell JA
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Identification and evaluation of network modules for the prognosis of basal-like breast cancer.

Oncotarget
2015-07 | Journal article
Contributors: Hallett RM; Cockburn JG; Li B; Dvorkin-Gheva A; Hassell JA; Bane A
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

T Cells Engineered With Chimeric Antigen Receptors Targeting NKG2D Ligands Display Lethal Toxicity in Mice.

Molecular therapy : the journal of the American Society of Gene Therapy
2015-06 | Journal article
Contributors: VanSeggelen H; Hammill JA; Dvorkin-Gheva A; Tantalo DG; Kwiecien JM; Denisova GF; Rabinovich B; Wan Y; Bramson JL
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Nucleus accumbens core and pathogenesis of compulsive checking.

Behavioural pharmacology
2015-02 | Journal article
Contributors: Ballester González J; Dvorkin-Gheva A; Silva C; Foster JA; Szechtman H
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

5-HT2A/C receptors do not mediate the attenuation of compulsive checking by mCPP in the quinpirole sensitization rat model of obsessive-compulsive disorder (OCD).

Behavioural brain research
2014-11 | Journal article
Contributors: Tucci MC; Dvorkin-Gheva A; Johnson E; Wong M; Szechtman H
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Identification of a novel luminal molecular subtype of breast cancer.

PloS one
2014-07 | Journal article
Contributors: Dvorkin-Gheva A; Hassell JA
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Performance of compulsive behavior in rats is not a unitary phenomenon - validation of separate functional components in compulsive checking behavior.

The European journal of neuroscience
2014-06 | Journal article
Contributors: Tucci MC; Dvorkin-Gheva A; Johnson E; Cheon P; Taji L; Agarwal A; Foster J; Szechtman H
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Separate mechanisms for development and performance of compulsive checking in the quinpirole sensitization rat model of obsessive-compulsive disorder (OCD).

Psychopharmacology
2014-02 | Journal article
Contributors: Tucci MC; Dvorkin-Gheva A; Sharma R; Taji L; Cheon P; Peel J; Kirk A; Szechtman H
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Quinpirole and 8-OH-DPAT induce compulsive checking behavior in male rats by acting on different functional parts of an OCD neurocircuit.

Behavioural pharmacology
2013-02 | Journal article
Contributors: Alkhatib AH; Dvorkin-Gheva A; Szechtman H
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Effects of the serotonergic agonist mCPP on male rats in the quinpirole sensitization model of obsessive-compulsive disorder (OCD).

Psychopharmacology
2013-01 | Journal article
Contributors: Tucci MC; Dvorkin-Gheva A; Graham D; Amodeo S; Cheon P; Kirk A; Peel J; Taji L; Szechtman H
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

A gene signature for predicting outcome in patients with basal-like breast cancer.

Scientific reports
2012-01 | Journal article
Contributors: Hallett RM; Dvorkin-Gheva A; Bane A; Hassell JA
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Hormone receptor and ERBB2 status in gene expression profiles of human breast tumor samples.

PloS one
2011-10 | Journal article
Contributors: Dvorkin-Gheva A; Hassell JA
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

Validation of the dimensionality emergence assay for the measurement of innate anxiety in laboratory mice.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
2011-07 | Journal article
Contributors: Jain A; Dvorkin A; Fonio E; Golani I; Gross CT
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central

An algorithm to discover gene signatures with predictive potential.

Journal of experimental & clinical cancer research : CR
2010-09 | Journal article
Contributors: Hallett RM; Dvorkin A; Gabardo CM; Hassell JA
Source: Self-asserted source
Anna Dvorkin-Gheva via Europe PubMed Central