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Works (25)

Imprinting of serum neutralizing antibodies by Wuhan-1 mRNA vaccines

Nature
2024-06-27 | Journal article
Contributors: Chieh-Yu Liang; Saravanan Raju; Zhuoming Liu; Yuhao Li; Guha Asthagiri Arunkumar; James Brett Case; Suzanne M. Scheaffer; Seth J. Zost; Cory M. Acreman; Matthew Gagne et al.
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Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds

Nature Communications
2024-01-30 | Journal article
Contributors: Eike-Christian Wamhoff; Larance Ronsard; Jared Feldman; Grant A. Knappe; Blake M. Hauser; Anna Romanov; James Brett Case; Shilpa Sanapala; Evan C. Lam; Kerri J. St. Denis et al.
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Characterization of the SARS-CoV-2 BA.5.5 and BQ.1.1 Omicron variants in mice and hamsters

Journal of Virology
2023-09-28 | Journal article
Contributors: James Brett Case; Suzanne M. Scheaffer; Tamarand L. Darling; Traci L. Bricker; Lucas J. Adams; Houda H. Harastani; Reed Trende; Shilpa Sanapala; Daved H. Fremont; Adrianus C. M. Boon et al.
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Neutralization, effector function and immune imprinting of Omicron variants

Nature
2023-09-21 | Journal article
Contributors: Amin Addetia; Luca Piccoli; James Brett Case; Young-Jun Park; Martina Beltramello; Barbara Guarino; Ha Dang; Guilherme Dias de Melo; Dora Pinto; Kaitlin Sprouse et al.
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A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins

Nature Chemical Biology
2023-03 | Journal article
Contributors: Vikas Chonira; Young D. Kwon; Jason Gorman; James Brett Case; Zhiqiang Ku; Rudo Simeon; Ryan G. Casner; Darcy R. Harris; Adam S. Olia; Tyler Stephens et al.
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Therapeutic and vaccine-induced cross-reactive antibodies with effector function against emerging Omicron variants

2023-01-17 | Preprint
Contributors: Amin Addetia; Luca Piccoli; James Brett Case; Young-Jun Park; Martina Beltramello; Barbara Guarino; Ha Dang; Dora Pinto; Suzanne M. Scheaffer; Kaitlin Sprouse et al.
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Resilience of S309 and AZD7442 monoclonal antibody treatments against infection by SARS-CoV-2 Omicron lineage strains

Nature Communications
2022-07-02 | Journal article
Contributors: James Brett Case; Samantha Mackin; John M. Errico; Zhenlu Chong; Emily A. Madden; Bradley Whitener; Barbara Guarino; Michael A. Schmid; Kim Rosenthal; Kuishu Ren et al.
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The Translational Landscape of SARS-CoV-2-infected Cells Reveals Suppression of Innate Immune Genes

mBio
2022-06-28 | Journal article
Contributors: Maritza Puray-Chavez; Nakyung Lee; Kasyap Tenneti; Yiqing Wang; Hung R. Vuong; Yating Liu; Amjad Horani; Tao Huang; Sean P. Gunsten; James B. Case et al.
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Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice

Science Translational Medicine
2022-05-25 | Journal article
Contributors: Andrew C. Hunt; James Brett Case; Young-Jun Park; Longxing Cao; Kejia Wu; Alexandra C. Walls; Zhuoming Liu; John E. Bowen; Hsien-Wei Yeh; Shally Saini et al.
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JIB-04 Has Broad-Spectrum Antiviral Activity and Inhibits SARS-CoV-2 Replication and Coronavirus Pathogenesis

mBio
2022-02-22 | Journal article
Contributors: Juhee Son; Shimeng Huang; Qiru Zeng; Traci L. Bricker; James Brett Case; Jinzhu Zhou; Ruochen Zang; Zhuoming Liu; Xinjian Chang; Tamarand L. Darling et al.
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SARS-CoV-2 Causes Lung Infection without Severe Disease in Human ACE2 Knock-In Mice

Journal of Virology
2022-01-12 | Journal article
Contributors: Emma S. Winkler; Rita E. Chen; Fahmida Alam; Soner Yildiz; James Brett Case; Melissa B. Uccellini; Michael J. Holtzman; Adolfo Garcia-Sastre; Michael Schotsaert; Michael S. Diamond et al.
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Structural mechanism of SARS-CoV-2 neutralization by two murine antibodies targeting the RBD

Cell Reports
2021-10 | Journal article
Contributors: John M. Errico; Haiyan Zhao; Rita E. Chen; Zhuoming Liu; James Brett Case; Meisheng Ma; Aaron J. Schmitz; Michael J. Rau; James A.J. Fitzpatrick; Pei-Yong Shi et al.
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Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail

Nature Microbiology
2021-09-21 | Journal article
Contributors: Jinhui Dong; Seth J. Zost; Allison J. Greaney; Tyler N. Starr; Adam S. Dingens; Elaine C. Chen; Rita E. Chen; James Brett Case; Rachel E. Sutton; Pavlo Gilchuk et al.
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In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains

Nature
2021-08-05 | Journal article
Contributors: Rita E. Chen; Emma S. Winkler; James Brett Case; Ishmael D. Aziati; Traci L. Bricker; Astha Joshi; Tamarand L. Darling; Baoling Ying; John M. Errico; Swathi Shrihari et al.
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SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses

Nature
2021-08-05 | Journal article
Contributors: Jackson S. Turner; Jane A. O’Halloran; Elizaveta Kalaidina; Wooseob Kim; Aaron J. Schmitz; Julian Q. Zhou; Tingting Lei; Mahima Thapa; Rita E. Chen; James Brett Case et al.
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In vivo monoclonal antibody efficacy against SARS-CoV-2 variant strains

2021-04-23 | Preprint
Contributors: Michael Diamond; Rita Chen; Emma Winkler; James Case; Ishmael Aziati; Traci Bricker; Astha Joshi; Tamarand Darling; Baoling Ying; John Errico et al.
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Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies

Nature Medicine
2021-04-04 | Journal article
Contributors: Rita E. Chen; Xianwen Zhang; James Brett Case; Emma S. Winkler; Yang Liu; Laura A. VanBlargan; Jianying Liu; John M. Errico; Xuping Xie; Naveenchandra Suryadevara et al.
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Assessment of serological assays for identifying high titer convalescent plasma

2021-03-28 | Other
Contributors: Christopher W. Farnsworth; James Brett Case; Karl Hock; Rita E. Chen; Jane A. O’Halloran; Rachel Presti; Charles W. Goss; Adriana M. Rauseo; Ali Ellebedy; Elitza S. Theel et al.
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SARS-CoV-2 mRNA vaccines induce a robust germinal centre reaction in humans

2021-03-10 | Preprint
Contributors: Ali Ellebedy; Jackson Turner; Jane O'Halloran; Elizaveta Kalaidina; Wooseob Kim; Aaron Schmitz; Tingting Lei; Mahima Thapa; Rita Chen; James Case et al.
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SARS-CoV-2 variants show resistance to neutralization by many monoclonal and serum-derived polyclonal antibodies

2021-02-10 | Preprint
Contributors: Michael Diamond; Rita Chen; Xuping Xie; James Case; Xianwen Zhang; Laura VanBlargan; Yang Liu; Jianying Liu; John Errico; Emma Winkler et al.
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LDLRAD3 is a receptor for Venezuelan equine encephalitis virus

Nature
2020-12-10 | Journal article
Contributors: Hongming Ma; Arthur S. Kim; Natasha M. Kafai; James T. Earnest; Aadit P. Shah; James Brett Case; Katherine Basore; Theron C. Gilliland; Chengqun Sun; Christopher A. Nelson et al.
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De novo design of picomolar SARS-CoV-2 miniprotein inhibitors

Science
2020-10-23 | Journal article
Contributors: Longxing Cao; Inna Goreshnik; Brian Coventry; James Brett Case; Lauren Miller; Lisa Kozodoy; Rita E. Chen; Lauren Carter; Alexandra C. Walls; Young-Jun Park et al.
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Growth, detection, quantification, and inactivation of SARS-CoV-2

Virology
2020-09 | Journal article
Contributors: James Brett Case; Adam L. Bailey; Arthur S. Kim; Rita E. Chen; Michael S. Diamond
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Potently neutralizing and protective human antibodies against SARS-CoV-2

Nature
2020-08-20 | Journal article
Contributors: Seth J. Zost; Pavlo Gilchuk; James Brett Case; Elad Binshtein; Rita E. Chen; Joseph P. Nkolola; Alexandra Schäfer; Joseph X. Reidy; Andrew Trivette; Rachel S. Nargi et al.
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A Potently Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection

The Journal of Immunology
2020-08-15 | Journal article
Contributors: Wafaa B. Alsoussi; Jackson S. Turner; James B. Case; Haiyan Zhao; Aaron J. Schmitz; Julian Q. Zhou; Rita E. Chen; Tingting Lei; Amena A. Rizk; Katherine M. McIntire et al.
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