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Laboratory for Computational Neuroscience
European Institute for Theoretical Neuroscience

Other IDs

Loop profile: 10022

Keywords

Computational neuroscience, theoretical neuroscience, neurophysics

Countries

France

Biography

Research Director at CNRS, Director of the European Institute for Theoretical Neuroscience, Editor in Chief of the Journal of Computational Neuroscience.

Activities

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Employment (1)

CNRS: Paris-Saclay, FR

2000-10-01 to present | Research Director (Paris-Saclay Institute of Neuroscience (NeuroPSI))
Employment
Source: Self-asserted source
Alain Destexhe

Education and qualifications (3)

Universite Laval: Quebec, QC, CA

1995-07-01 to 2000-06-30 | Assistant Professor (Department of Physiology)
Education
Source: Self-asserted source
Alain Destexhe

Salk Institute: San Diego, CA, US

1992-08-01 to 1995-06-30 | Postdoctoral researcher (CNL)
Education
Source: Self-asserted source
Alain Destexhe

Universite Libre de Bruxelles: Bruxelles, BE

1985-09-01 to 1992-03-21 | PhD (Chemical Physics)
Education
Source: Self-asserted source
Alain Destexhe

Professional activities (1)

CNRS Délégation Paris Michel-Ange: Paris, Île-de-France, FR

2008-01-12 | Silver Medal
Distinction
Source: Self-asserted source
Alain Destexhe

Works (50 of 280)

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Biologically realistic mean field model of spiking neural networks with fast and slow inhibitory synapses

2025-03-02 | Preprint
DOI: 10.1101/2025.02.28.640853
Contributors: Claudio Di Geronimo; Alain Destexhe; Matteo di Volo
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Crossref

Entropy and Complexity Tools Across Scales in Neuroscience: A Review

Entropy
2025-01-24 | Journal article
DOI: 10.3390/e27020115
Contributors: Rodrigo Cofré; Alain Destexhe
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Transcranial direct current stimulation modulates primate brain dynamics across states of consciousness

2024-10-04 | Preprint
DOI: 10.7554/eLife.101688.1
Contributors: Guylaine Hoffner; Pablo Castro; Lynn Uhrig; Camilo M Signorelli; Morgan Dupont; Jordy Tasserie; Alain Destexhe; Rodrigo Cofre; Jacobo Sitt; Bechir Jarraya
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Crossref

Transcranial direct current stimulation modulates primate brain dynamics across states of consciousness

2024-10-04 | Preprint
DOI: 10.7554/eLife.101688
Contributors: Guylaine Hoffner; Pablo Castro; Lynn Uhrig; Camilo M Signorelli; Morgan Dupont; Jordy Tasserie; Alain Destexhe; Rodrigo Cofre; Jacobo Sitt; Bechir Jarraya
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Crossref

A computational approach to evaluate how molecular mechanisms impact large-scale brain activity

2024-10-01 | Preprint
DOI: 10.21203/rs.3.rs-4610184/v1
Contributors: Alain Destexhe; Maria Sacha; Federico Tesler; Rodrigo Cofre
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Crossref

Dynamical structure-function correlations provide robust and generalizable signatures of consciousness in humans

Communications Biology
2024-09-30 | Journal article
DOI: 10.1038/s42003-024-06858-3
Contributors: Pablo Castro; Andrea Luppi; Enzo Tagliazucchi; Yonatan S. Perl; Lorina Naci; Adrian M. Owen; Jacobo D. Sitt; Alain Destexhe; Rodrigo Cofré
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EEG-fMRI in awake rat and whole-brain simulations show decreased brain responsiveness to sensory stimulations during absence seizures

eLife
2024-07-08 | Journal article
DOI: 10.7554/eLife.90318.4
Contributors: Petteri Stenroos; Isabelle Guillemain; Federico Tesler; Olivier Montigon; Nora Collomb; Vasile Stupar; Alain Destexhe; Veronique Coizet; Olivier David; Emmanuel L Barbier
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Crossref

EEG-fMRI in awake rat and whole-brain simulations show decreased brain responsiveness to sensory stimulations during absence seizures

eLife
2024-07-08 | Journal article
DOI: 10.7554/eLife.90318
Contributors: Petteri Stenroos; Isabelle Guillemain; Federico Tesler; Olivier Montigon; Nora Collomb; Vasile Stupar; Alain Destexhe; Veronique Coizet; Olivier David; Emmanuel L Barbier
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Crossref

Transcranial direct current stimulation modulates primate brain dynamics across states of consciousness.

2024-03-30 | Preprint
DOI: 10.1101/2024.03.27.586806
Contributors: Guylaine Hoffner; Pablo Castro; Lynn Uhrig; Camilo Miguel Signorelli; Morgan Dupont; Jordy Tasserie; Alain Destexhe; Rodrigo Cofre; Jacobo Sitt; Bechir Jarraya
Source: check_circle
Crossref

Local orchestration of distributed functional patterns supporting loss and restoration of consciousness in the primate brain

Nature Communications
2024-03-11 | Journal article
DOI: 10.1038/s41467-024-46382-w
Contributors: Andrea I. Luppi; Lynn Uhrig; Jordy Tasserie; Camilo M. Signorelli; Emmanuel A. Stamatakis; Alain Destexhe; Bechir Jarraya; Rodrigo Cofre
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Vast Parameter Space Exploration of the Virtual Brain: A Modular Framework for Accelerating the Multi-Scale Simulation of Human Brain Dynamics

Applied Sciences
2024-03-06 | Journal article
DOI: 10.3390/app14052211
Contributors: Michiel van der Vlag; Lionel Kusch; Alain Destexhe; Viktor Jirsa; Sandra Diaz-Pier; Jennifer S. Goldman
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Asynchronous and Slow-Wave Oscillatory States in Connectome-Based Models of Mouse, Monkey and Human Cerebral Cortex

Applied Sciences
2024-01-26 | Journal article
DOI: 10.3390/app14031063
Contributors: Maria Sacha; Jennifer S. Goldman; Lionel Kusch; Alain Destexhe
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Dynamical structure-function correlations provide robust and generalizable signatures of consciousness in humans

2024-01-23 | Preprint
DOI: 10.21203/rs.3.rs-3778096/v1
Contributors: Rodrigo Cofre; Pablo Castro; Enzo Tagliazucchi; Yonathan Sanz Perl; Lorina Naci; Adrian Owen; Jacobo Sitt; Alain Destexhe; Andrea Luppi
Source: check_circle
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Dynamics and bifurcation structure of a mean-field model of adaptive exponential integrate-and-fire networks

2023-12-10 | Preprint
DOI: 10.1101/2023.12.09.570909
Contributors: Lionel Kusch; Damien Depannemaecker; Alain Destexhe; Viktor Jirsa
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Crossref

A Multi-Scale Study of Thalamic State-Dependent Responsiveness

2023-12-04 | Preprint
DOI: 10.1101/2023.12.02.567941
Contributors: Jorin Overwiening; Federico Tesler; Domenico Guarino; Alain Destexhe
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High-Density Exploration of Activity States in a Multi-Area Brain Model

Neuroinformatics
2023-11-20 | Journal article
DOI: 10.1007/s12021-023-09647-1
Contributors: David Aquilué-Llorens; Jennifer S. Goldman; Alain Destexhe
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Crossref

Asynchronous and slow-wave oscillatory states in connectome-based models of mouse, monkey and human cerebral cortex

2023-08-04 | Preprint
DOI: 10.1101/2023.08.03.551869
Contributors: Maria Sacha; Jennifer S. Goldman; Lionel Kusch; Alain Destexhe
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Dynamical properties of self-sustained and driven neural networks

2023-07-18 | Preprint
DOI: 10.1101/2023.07.15.549166
Contributors: Jules Bouté; Alain Destexhe
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Local Orchestration of Global Functional Patterns Supporting Loss and Restoration of Consciousness in the Primate Brain

2023-07-03 | Preprint
DOI: 10.1101/2023.06.30.547281
Contributors: Andrea I. Luppi; Lynn Uhrig; Jordy Tasserie; Camilo M. Signorelli; Emmanuel Stamatakis; Alain Destexhe; Bechir Jarraya; Rodrigo Cofre
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Consequence assessment and behavioral patterns of inhibition in decision-making: modelling its underlying mechanisms

2023-02-15 | Preprint
DOI: 10.1101/2023.02.14.528595
Contributors: Gloria Cecchini; Michael DePass; Emre Baspinar; Marta Andujar; Surabhi Ramawat; Pierpaolo Pani; Stefano Ferraina; Alain Destexhe; Rubén Moreno-Bote; Ignasi Cos
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Experimental and computational analysis of REM sleep distributed cortical activity in mice

2023-01-20 | Preprint
DOI: 10.1101/2023.01.19.524685
Contributors: Mathias Peuvrier; Laura Fernandez; Sylvain Crochet; Alain Destexhe; Paul Salin
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Crossref

Dynamical models to evaluate structure–function relationships in network neuroscience

Nature Reviews Neuroscience
2022-12 | Journal article
DOI: 10.1038/s41583-022-00646-w
Contributors: Andrea I. Luppi; Joana Cabral; Rodrigo Cofre; Alain Destexhe; Gustavo Deco; Morten L. Kringelbach
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Crossref

Noise Enhancement of Neural Information Processing

Entropy
2022-12-16 | Journal article
DOI: 10.3390/e24121837
Contributors: Alain Destexhe
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Crossref
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A Model for the Propagation of Seizure Activity in Normal Brain Tissue

eneuro
2022-11 | Journal article
DOI: 10.1523/ENEURO.0234-21.2022
Contributors: Damien Depannemaecker; Mallory Carlu; Jules Bouté; Alain Destexhe
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Crossref

A reformulation of the brain’s magneto-quasistatic approximation and a formalism for the long-distance magnetic field generated by populations of neurons

Journal of Applied Physics
2022-11-07 | Journal article
DOI: 10.1063/5.0094862
Contributors: Alexis O. García Rodríguez; Alain Destexhe
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Crossref

Awake perception is associated with dedicated neuronal assemblies in the cerebral cortex

Nature Neuroscience
2022-10 | Journal article
DOI: 10.1038/s41593-022-01168-5
Contributors: Anton Filipchuk; Joanna Schwenkgrub; Alain Destexhe; Brice Bathellier
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Crossref

A method to convert neural signals into sound sequences

The Journal of the Acoustical Society of America
2022-06 | Journal article
DOI: 10.1121/10.0011549
Contributors: Alain Destexhe; Luc Foubert
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Crossref

Reproducible patterns of neural activity without attractors in cortical networks

2022-05-25 | Preprint
DOI: 10.1101/2022.05.24.493230
Contributors: Domenico Guarino; Anton Filipchuk; Alain Destexhe
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Crossref

Extracellular and intracellular components of the impedance of neural tissue

Biophysical Journal
2022-03 | Journal article
DOI: 10.1016/j.bpj.2022.02.022
Contributors: Claude Bedard; Charlotte Piette; Laurent Venance; Alain Destexhe
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Linking Brain Structure, Activity, and Cognitive Function through Computation

eneuro
2022-03 | Journal article
DOI: 10.1523/ENEURO.0316-21.2022
Contributors: Katrin Amunts; Javier DeFelipe; Cyriel Pennartz; Alain Destexhe; Michele Migliore; Philippe Ryvlin; Steve Furber; Alois Knoll; Lise Bitsch; Jan G. Bjaalie et al.
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Adaptive control of Lipschitz time-delay systems by sigma modification with application to neuronal population dynamics

Systems & Control Letters
2022-01 | Journal article
DOI: 10.1016/j.sysconle.2021.105082
Contributors: Jakub Orłowski; Antoine Chaillet; Alain Destexhe; Mario Sigalotti
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Crossref

Conductance-Based Adaptive Exponential Integrate-and-Fire Model

Neural Comput
2021 | Journal article
Source: Self-asserted source
Alain Destexhe

Properties and computational consequences of fast dendritic spikes during natural behavior

2021-12-27 | Preprint
DOI: 10.1101/2021.12.27.474234
Contributors: Alain Destexhe; Mayank Mehta
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A network model of the modulation of gamma oscillations by NMDA receptors in cerebral cortex

2021-12-23 | Preprint
DOI: 10.1101/2021.12.21.473671
Contributors: Eduarda Susin; Alain Destexhe
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Integration, coincidence detection and resonance in networks of spiking neurons expressing Gamma oscillations and asynchronous states

PLOS Computational Biology
2021-09-16 | Journal article
DOI: 10.1371/journal.pcbi.1009416
Contributors: Eduarda Susin; Arvind Kumar; Alain Destexhe
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Crossref

An Anatomically Constrained Model of V1 Simple Cells Predicts the Coexistence of Push–Pull and Broad Inhibition

The Journal of Neuroscience
2021-09-15 | Journal article
DOI: 10.1523/JNEUROSCI.0928-20.2021
Contributors: M. Morgan Taylor; Diego Contreras; Alain Destexhe; Yves Frégnac; Jan Antolik
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Crossref

A comprehensive neural simulation of slow-wave sleep and highly responsive wakefulness dynamics

2021-09-01 | Other
DOI: 10.1101/2021.08.31.458365
Contributors: Jennifer S. Goldman; Lionel Kusch; Bahar Hazal Yalçinkaya; Damien Depannemaecker; Trang-Anh E. Nghiem; Viktor Jirsa; Alain Destexhe
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Crossref

Awake perception is associated with dedicated neuronal assemblies in cerebral cortex

2021-09-01 | Preprint
DOI: 10.1101/2021.08.31.458322
Contributors: Anton Filipchuk; Joanna Schwenkgrub; Alain Destexhe; Brice Bathellier
Source: check_circle
Crossref

Extracellular and intracellular components of the impedance of neural tissue

2021-08-06 | Preprint
DOI: 10.1101/2021.08.05.455210
Contributors: Claude Bedard; Charlotte Piette; Laurent Venance; Alain Destexhe
Source: check_circle
Crossref

Integration, coincidence detection and resonance in networks of spiking neurons expressing gamma oscillations and asynchronous states

2021-05-03 | Preprint
DOI: 10.1101/2021.05.03.442436
Contributors: Eduarda Susin; Alain Destexhe
Source: check_circle
Crossref

A key role of astrocytic calcium dynamics to link neuronal activity with the BOLD signal

2021-04-23 | Preprint
DOI: 10.1101/2021.04.23.441146
Contributors: Federico Tesler; Marja-Leena Linne; Alain Destexhe
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Crossref

Is There Sufficient Evidence for Criticality in Cortical Systems?

eneuro
2021-03 | Journal article
DOI: 10.1523/ENEURO.0551-20.2021
Contributors: Alain Destexhe; Jonathan D. Touboul
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Modulation of intercolumnar synchronization by endogenous electric fields in cerebral cortex

Science Advances
2021-03-05 | Journal article
DOI: 10.1126/sciadv.abc7772
Contributors: Beatriz Rebollo; Bartosz Telenczuk; Alvaro Navarro-Guzman; Alain Destexhe; Maria V. Sanchez-Vives
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Cholinergic Switch between Two Types of Slow Waves in Cerebral Cortex

Cereb Cortex
2020 | Journal article
Source: Self-asserted source
Alain Destexhe

Experimental and Computational Study on Motor Control and Recovery After Stroke: Toward a Constructive Loop Between Experimental and Virtual Embodied Neuroscience

Front Syst Neurosci
2020 | Journal article
Source: Self-asserted source
Alain Destexhe

Brain-scale emergence of slow-wave synchrony and highly responsive asynchronous states based on biologically realistic population models simulated in The Virtual Brain

2020-12-29 | Preprint
DOI: 10.1101/2020.12.28.424574
Contributors: Jennifer S. Goldman; Lionel Kusch; Bahar Hazal Yalcinkaya; Damien Depannemaecker; Trang-Anh E. Nghiem; Viktor Jirsa; Alain Destexhe
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A kernel-based method to calculate local field potentials from networks of spiking neurons

J Neurosci Methods
2020-10 | Journal article
Source: Self-asserted source
Alain Destexhe

Modelling unitary fields and the single-neuron contribution to local field potentials in the hippocampus

J Physiol
2020-09 | Journal article
Source: Self-asserted source
Alain Destexhe

Modelling unitary fields and the single‐neuron contribution to local field potentials in the hippocampus

The Journal of Physiology
2020-09 | Journal article
DOI: 10.1113/JP279452
Contributors: Maria Teleńczuk; Bartosz Teleńczuk; Alain Destexhe
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Crossref

A mean-field approach to the dynamics of networks of complex neurons, from nonlinear Integrate-and-Fire to Hodgkin-Huxley models

J Neurophysiol
2020-03 | Journal article
Source: Self-asserted source
Alain Destexhe
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Peer review (5 reviews for 4 publications/grants)

Review activity for eLife (1)
Review activity for Nature communications (1)
Review activity for Nature methods. (1)
Review activity for PloS one. (2)
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