Personal information

Iran, Malaysia, United States

Biography

Roozbeh. H, BSc, MSc, PhD, is a Human Geneticist. He possesses expertise in transcriptomics and the molecular mechanisms of metabolic disorders and cancers. His research applies advanced transcriptomics techniques to uncover the complexities of these conditions. His doctoral thesis focused on identifying non-invasive diagnostic biomarkers, particularly non-coding RNAs such as microRNAs (miRNAs) and long non-coding RNAs (lncRNAs), and exploring their roles as diagnostic and prognostic indicators. Dr. Roozbeh's expertise includes transcriptomic data analysis to investigate gene expression patterns, genetic variants, and their evolution under genetic and clinical influences. He is passionate about uncovering the complexities of metabolic and cancer-related conditions in patients through personalized medicine, cutting-edge molecular diagnostics, and innovative therapeutic approaches.

Activities

Works (14)

A high-throughput RNA sequency of peripheral blood mononuclear cells reveals on inflammatory state in women with PCOS

Archives of Medical Research
2025 | Journal article
Contributors: Heidarzadehpilehrood, Roozbeh; Pirhoushiaran, Maryam; Osman, Malina Binti; Ling, King-Hwa; Hamid, Habibah Abdul
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Upregulated PCAT-1 predicts poor prognosis and reduced immune cell infiltration in head and neck squamous cell carcinoma through the miR-145-5p / FSCN-1 axis

Molecular Biology Reports
2025-12 | Journal article
Contributors: Maryam Pirhoushiaran; Roozbeh Heidarzadehpilehrood; Mahnoosh Mokhtarinejad; Sara Hesami; Nima Rezaei; Abbas Shakoori Farahani
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Dysregulated key long non-coding RNAs TP53TG1, RFPL1S, DLEU1, and HCG4 associated with epithelial-mesenchymal transition (EMT) in castration-resistant prostate cancer

Advances in Cancer Biology - Metastasis
2025-03 | Journal article
Contributors: Tahmineh Mehrabi; Roozbeh Heidarzadehpilehrood; Meysam Mobasheri; Tabassom Sobati; Masoumeh Heshmati; Maryam Pirhoushiaran
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Silencing of long non-coding RNAs MIR22HG, LNCTAM34A, and TP53TG1 triggers cell survival/proliferation and inhibits apoptosis in women's breast cancer

Advances in Cancer Biology - Metastasis
2025-03 | Journal article
Contributors: Ahmed Al-Kateb; Roozbeh Heidarzadehpilehrood; Maryam Pirhoushiaran; Rasoul Abdollahzadeh; Mojtaba Saffari; Keivan Majidzadeh-A; Sepideh Mehrpoor Layeghi; Mohammad Hossein Modarressi
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Vitamin D receptor (VDR) gene polymorphisms and risk for polycystic ovary syndrome and infertility: An updated systematic review and meta-analysis

Metabolism Open
2025-03 | Journal article
Contributors: Roozbeh Heidarzadehpilehrood; Habibah Abdul Hamid; Maryam Pirhoushiaran
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Biomarker potential of competing endogenous RNA networks in Polycystic Ovary Syndrome (PCOS)

Non-Coding RNA Research
2024 | Journal article
Contributors: Heidarzadehpilehrood, Roozbeh; Pirhoushiaran, Maryam
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Upregulated long non-coding RNAs TMPO-AS1, DDX11-AS1, and POLE gene expression predict poor prognosis in head and neck squamous cell carcinoma (HNSCC)

Gene Reports
2024 | Journal article
Contributors: Mokhtarinejad, Mahnoosh; Pirhoushiaran, Maryam; Heidarzadehpilehrood, Roozbeh; Hesami, Sara; Azmoudeh-Ardalan, Farid; Farahani, Abbas Shakoori
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Upregulated long non-coding RNAs TMPO-AS1, DDX11-AS1, and POLE gene expression predict poor prognosis in head and neck squamous cell carcinoma (HNSCC) (vol 36, 101942, 2024)

Gene Reports
2024 | Journal article
Contributors: Mokhtarinejad, Mahnoosh; Pirhoushiaran, Maryam; Heidarzadehpilehrood, Roozbeh; Hesami, Sara; Azmoudeh-Ardalan, Farid; Farahani, Abbas Shakoori
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Unveiling Key Biomarkers and Therapeutic Drugs in Polycystic Ovary Syndrome (PCOS) Through Pathway Enrichment Analysis and Hub Gene-miRNA Networks

Iranian Journal of Pharmaceutical Research
2023 | Journal article
Contributors: Heidarzadehpilehrood, Roozbeh; Pirhoushiaran, Maryam; Osman, Malina Binti; Ling, King-Hwa; Hamid, Habibah Abdul
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Weighted Gene Co-Expression Network Analysis (WGCNA) Discovered Novel Long Non-Coding RNAs for Polycystic Ovary Syndrome

Biomedicines
2023 | Journal article
Contributors: Heidarzadehpilehrood, Roozbeh; Pirhoushiaran, Maryam; Osman, Malina Binti; Hamid, Habibah Abdul; Ling, King-Hwa
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A comprehensive bioinformatic analysis revealed novel MicroRNA biomarkers of Parkinson's disease

Cell Biology International
2022 | Journal article
Contributors: Rahimpour, Alireza; Heidarzadehpilehrood, Roozbeh; Abdollahi, Sepideh; Ranjbari, Haidar; Shams, Zinat; Ghasemi, Seyed Abbas; Najmaei, Shima; Pirhoushiaran, Maryam
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A Review on <i>CYP11A1</i>, <i>CYP17A1</i>, and <i>CYP19A1</i> Polymorphism Studies: Candidate Susceptibility Genes for Polycystic Ovary Syndrome (PCOS) and Infertility

Genes
2022 | Journal article
Contributors: Heidarzadehpilehrood, Roozbeh; Pirhoushiaran, Maryam; Abdollahzadeh, Rasoul; Osman, Malina Binti; Sakinah, Maryam; Nordin, Norshariza; Hamid, Habibah Abdul
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Bioinformatics Analysis of MicroRNA Profiles Unveils Novel Biological Markers of Alzheimer's Disease

Neurochemical Journal
2022 | Journal article
Contributors: Rahimpour, Alireza; Heidarzadehpilehrood, Roozbeh; Aghel, Majid; Jamalpoor, Zahra; Heydarian, Parichehr; Ghasemi, Seyed Abbas; Pirhoushiaran, Maryam
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Association of Vitamin D receptor gene polymorphisms and clinical/severe outcomes of COVID-19 patients

Infection, Genetics and Evolution
2021 | Journal article
Contributors: Abdollahzadeh, Rasoul; Shushizadeh, Mohammad Hossein; Barazandehrokh, Mina; Choopani, Sepideh; Azarnezhad, Asaad; Paknahad, Sahereh; Pirhoushiaran, Maryam; Makani, S. Zahra; Yeganeh, Razieh Zarifian; Al-Kateb, Ahmed et al.
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Peer review (36 reviews for 14 publications/grants)

Review activity for Biochemical genetics. (2)
Review activity for Biomolecules & biomedicine (1)
Review activity for Biomolecules & biomedicine (2)
Review activity for BMC complementary medicine and therapies. (1)
Review activity for BMC immunology (1)
Review activity for BMC women's health (4)
Review activity for Discover Oncology. (3)
Review activity for European journal of medical research. (1)
Review activity for Hereditas. (1)
Review activity for Journal of ovarian research. (10)
Review activity for Microbiome (1)
Review activity for Middle East Fertility Society Journal. (1)
Review activity for Molecular neurobiology. (2)
Review activity for Scientific reports. (6)