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nference
Publications

Keywords

virus, infectious diseases, evolution, electronic health record, clinical notes, digital pathology, electrophysiology, genetics, genomics, proteomics, RNA-sequencing, Single cell sequencing, Genomics, Viral evolution, Neural networks, Machine learning, Artificial Intelligence

Countries

United States, Canada, India

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Employment (1)

Nference (United States): Cambridge, Massachusetts, US

2013 to present | Founder & Chief Scientific Officer
Employment
Source: Self-asserted source
Venky Soundararajan

Education and qualifications (3)

Harvard Medical School: Boston, MA, US

2011 to 2012 | Research Fellow (Genetics)
Education
Source: Self-asserted source
Venky Soundararajan

Massachusetts Institute of Technology: Cambridge, Massachusetts, US

2005 to 2010 | PhD (Biological Engineering)
Education
Source: Self-asserted source
Venky Soundararajan

Indian Institute of Technology Guwahati: Guwahati, Assam, IN

2001 to 2005 | B.Tech. (Electronics & Communications Engineering)
Education
Source: Self-asserted source
Venky Soundararajan

Works (29)

On the Origins of Omicron’s Unique Spike Gene Insertion

Vaccines
2022-09 | Journal article | Author
DOI: 10.3390/vaccines10091509
Contributors: A. J. Venkatakrishnan; Praveen Anand; Patrick Lenehan; Rohit Suratekar; Bharathwaj Raghunathan; Michiel Niesen; Venky Soundararajan
Source: check_circle
Multidisciplinary Digital Publishing Institute
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Preferred source (of 2)‎

Individuals with recent prior SARS-CoV-2 infection are at reduced risk of Omicron infection and associated hospitalization

2022-08-15 | Preprint
DOI: 10.1101/2022.08.10.22278641
Contributors: Mihika Nadig; Michiel JM Niesen; Patrick Lenehan; Vineet Agarwal; Jason Ross; Sankar Ardhanari; AJ Venkatakrishnan; Venky Soundararajan
Source: check_circle
Crossref

Quantifying the immunological distinctiveness of emerging SARS-CoV-2 variants in the context of prior regional herd exposure

PNAS Nexus
2022-07-01 | Journal article
DOI: 10.1093/pnasnexus/pgac105
Contributors: Michiel J M Niesen; Karthik Murugadoss; Patrick J Lenehan; Aron Marchler-Bauer; Jiyao Wang; Ryan Connor; J Rodney Brister; A J Venkatakrishnan; Venky Soundararajan; Karen E Nelson
Source: check_circle
Crossref

On the origin of Omicron’s unique Spike gene insertion

2022-06-06 | Preprint
DOI: 10.1101/2022.06.03.22275976
Contributors: AJ Venkatakrishnan; Praveen Anand; Patrick J Lenehan; Rohit Suratekar; Bharathwaj Raghunathan; Michiel JM Niesen; Venky Soundararajan
Source: check_circle
Crossref

Genetic alteration of human MYH6 is mimicked by SARS-CoV-2 polyprotein: mapping viral variants of cardiac interest

Cell Death Discovery
2022-03-21 | Journal article
DOI: 10.1038/s41420-022-00914-9
Contributors: Praveen Anand; Patrick J. Lenehan; Michiel Niesen; Unice Yoo; Dhruti Patwardhan; Marcelo Montorzi; A. J. Venkatakrishnan; Venky Soundararajan
Source: check_circle
Crossref

Quantifying the immunological distinctiveness of emerging SARS-CoV-2 variants in the context of prior regional herd exposure

2022-03-07 | Preprint
DOI: 10.1101/2022.03.06.22271974
Contributors: Michiel J.M. Niesen; Karthik Murugadoss; AJ Venkatakrishnan; Patrick J. Lenehan; Venky Soundararajan
Source: check_circle
Crossref

High diversity in Delta variant across countries revealed by genome‐wide analysis of SARS‐CoV‐2 beyond the Spike protein

Molecular Systems Biology
2022-02 | Journal article
DOI: 10.15252/msb.202110673
Contributors: Rohit Suratekar; Pritha Ghosh; Michiel J M Niesen; Gregory Donadio; Praveen Anand; Venky Soundararajan; A J Venkatakrishnan
Source: check_circle
Crossref

Omicron variant of SARS-CoV-2 harbors a unique insertion mutation of putative viral or human genomic origin

2021-12-03 | Preprint
DOI: 10.31219/osf.io/f7txy
Contributors: AJ Venkatakrishnan; Praveen Anand; Patrick Lenehan; Rohit Suratekar; Bharathwaj Raghunathan; Michiel J.M. Niesen; Venky Soundararajan
Source: check_circle
Crossref

Genetic alteration of human MYH6 is mimicked by SARS-CoV-2 polyprotein: mapping viral variants of cardiac interest

2021-11-29 | Other
DOI: 10.1101/2021.11.23.469709
Contributors: Praveen Anand; Patrick J. Lenehan; Michiel Niesen; Unice Yoo; Dhruti Patwardhan; Marcelo Montorzi; AJ Venkatakrishnan; Venky Soundararajan
Source: check_circle
Crossref

High diversity in Delta variant across countries revealed via genome-wide analysis of SARS-CoV-2 beyond the Spike protein

2021-09-02 | Other
DOI: 10.1101/2021.09.01.458647
Contributors: Rohit Suratekar; Pritha Ghosh; Michiel J.M. Niesen; Gregory Donadio; Praveen Anand; Venky Soundararajan; A.J. Venkatakrishnan
Source: check_circle
Crossref

Anemia during SARS-CoV-2 infection is associated with rehospitalization after viral clearance

iScience
2021-07 | Journal article
DOI: 10.1016/j.isci.2021.102780
Contributors: Patrick J. Lenehan; Eshwan Ramudu; A.J. Venkatakrishnan; Gabriela Berner; Reid McMurry; John C. O'Horo; Andrew D. Badley; William Morice, II; John Halamka; Venky Soundararajan
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Crossref

Building a best-in-class automated de-identification tool for electronic health records through ensemble learning

Patterns
2021-06 | Journal article
DOI: 10.1016/j.patter.2021.100255
Contributors: Karthik Murugadoss; Ajit Rajasekharan; Bradley Malin; Vineet Agarwal; Sairam Bade; Jeff R. Anderson; Jason L. Ross; William A. Faubion, Jr.; John D. Halamka; Venky Soundararajan et al.
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Crossref

Case fatality rates for COVID-19 are higher than case fatality rates for motor vehicle accidents for individuals over 40 years of age

2021-04-13 | Other
DOI: 10.1101/2021.04.09.21255193
Contributors: Arjun Puranik; Michiel J.M. Niesen; Emily Lindemer; Patrick Lenehan; Tudor Cristea-Platon; Colin Pawlowski; Venky Soundararajan
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Crossref

COVID-associated pediatric hospitalization and ICU admission trends across a multi-state health system and the broader US population

2021-04-05 | Other
DOI: 10.1101/2021.04.02.21254593
Contributors: AJ Venkatakrishnan; Colin Pawlowski; John C. O’Horo; Andrew Badley; John Halamka; Venky Soundararajan
Source: check_circle
Crossref

Enoxaparin is associated with lower rates of mortality than unfractionated Heparin in hospitalized COVID-19 patients

EClinicalMedicine
2021-03 | Journal article
DOI: 10.1016/j.eclinm.2021.100774
Contributors: Colin Pawlowski; AJ Venkatakrishnan; Christian Kirkup; Gabriela Berner; Arjun Puranik; John C. O'Horo; Andrew D. Badley; Venky Soundararajan
Source: check_circle
Crossref

COVID-19 hospitalization and ICU admission trends in younger patients and the pediatric population

2021-03-29 | Preprint
DOI: 10.31219/osf.io/cj4sf
Contributors: Colin Pawlowski; AJ Venkatakrishnan; Andrew D. Badley; John C O'Horo; John Halamka; Venky Soundararajan
Source: check_circle
Crossref

Counties with lower insurance coverage are associated with both slower vaccine rollout and higher COVID-19 incidence across the United States

2021-03-26 | Other
DOI: 10.1101/2021.03.24.21254270
Contributors: Emily Lindemer; Mayank Choudhary; Gregory Donadio; Colin Pawlowski; Venky Soundararajan
Source: check_circle
Crossref

Higher COVID-19 vaccination rates are linked to decreased county-level COVID-19 incidence across USA

2021-03-08 | Other
DOI: 10.1101/2021.03.05.21252946
Contributors: Arjun Puranik; AJ Venkatakrishnan; Colin Pawlowski; Bharathwaj Raghunathan; Eshwan Ramudu; Patrick Lenehan; Vineet Agarwal; Savita Jayaram; Mayank Choudhary; Venky Soundararajan
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Crossref

FDA-approved COVID-19 vaccines are effective per real-world evidence synthesized across a multi-state health system

2021-02-24 | Other
DOI: 10.21203/rs.3.rs-237155/v1
Contributors: Venky Soundararajan; Colin Pawlowski; Patrick Lenehan; Arjun Puranik; Vineet Agarwal; AJ Venkatakrishnan; Michiel Niesen; John O'Horo; Andrew Badley; John Halamka
Source: check_circle
Crossref

FDA-authorized COVID-19 vaccines are effective per real-world evidence synthesized across a multi-state health system

2021-02-18 | Other
DOI: 10.1101/2021.02.15.21251623
Contributors: Colin Pawlowski; Patrick Lenehan; Arjun Puranik; Vineet Agarwal; AJ Venkatakrishnan; Michiel J.M. Niesen; John C. O’Horo; Andrew D. Badley; John Halamka; Venky Soundararajan
Source: check_circle
Crossref

FDA-authorized COVID-19 vaccines are effective per real-world evidence synthesized across a multi-state health system

2021-02-17 | Preprint
DOI: 10.31219/osf.io/y6pdw
Contributors: Colin Pawlowski; Patrick Lenehan; Arjun Puranik; Vineet Agarwal; AJ Venkatakrishnan; Michiel J.M. Niesen; John C O'Horo; Andrew D. Badley; John Halamka; Venky Soundararajan
Source: check_circle
Crossref

Hair loss in females and thromboembolism in males are significantly enriched in post-acute sequelae of COVID (PASC) relative to recent medical history

2021-01-05 | Other
DOI: 10.1101/2021.01.03.20248997
Contributors: Venky Soundararajan; Samir Awasthi; Elliot Akama-Garren; Saran Liukasemsarn; John C O'Horo; Ryan T Hurt; Amy W Williams; Gregory J. Gores; Andrew D Badley; Praveen Anand et al.
Source: check_circle
Crossref

Building a Best-in-Class Automated De-identification Tool for Electronic Health Records Through Ensemble Learning

2020-12-23 | Other
DOI: 10.1101/2020.12.22.20248270
Contributors: Karthik Murugadoss; Ajit Rajasekharan; Bradley Malin; Vineet Agarwal; Sairam Bade; Jeff R. Anderson; Jason L. Ross; William A. Faubion, Jr.; John D. Halamka; Venky Soundararajan et al.
Source: check_circle
Crossref

Anemia is a risk factor for rehospitalization after SARS-CoV-2 clearance

2020-12-04 | Other
DOI: 10.1101/2020.12.02.20242958
Contributors: Patrick Lenehan; Eshwan Ramudu; AJ Venkatakrishnan; Gabriela Berner; Reid McMurry; John C. O’Horo; Andrew D. Badley; William Morice, II; John Halamka; Venky Soundararajan
Source: check_circle
Crossref

Enoxaparin is associated with lower rates of thrombosis, kidney injury, and mortality than Unfractionated Heparin in hospitalized COVID patients

2020-10-11 | Other
DOI: 10.1101/2020.10.06.20208025
Contributors: Colin Pawlowski; AJ Venkatakrishnan; Christian Kirkup; Gabriela Berner; Arjun Puranik; John C. O’Horo; Andrew D. Badley; Venky Soundararajan
Source: check_circle
Crossref

Benchmarking evolutionary tinkering underlying human–viral molecular mimicry shows multiple host pulmonary–arterial peptides mimicked by SARS-CoV-2

Cell Death Discovery
2020-10-02 | Journal article
DOI: 10.1038/s41420-020-00321-y
Contributors: A. J. Venkatakrishnan; Nikhil Kayal; Praveen Anand; Andrew D. Badley; George M. Church; Venky Soundararajan
Source: check_circle
Crossref

Multi-pronged human protein mimicry by SARS-CoV-2 reveals bifurcating potential for MHC detection and immune evasion

2020-06-19 | Preprint
DOI: 10.1101/2020.06.19.161620
Contributors: AJ Venkatakrishnan; Nikhil Kayal; Praveen Anand; Andrew D. Badley; George M. Church; Venky Soundararajan
Source: check_circle
Crossref

SARS-CoV-2 strategically mimics proteolytic activation of human ENaC

eLife
2020-05-26 | Journal article
DOI: 10.7554/eLife.58603
Contributors: Praveen Anand; Arjun Puranik; Murali Aravamudan; AJ Venkatakrishnan; Venky Soundararajan
Source: check_circle
Crossref

SARS-CoV-2 selectively mimics a cleavable peptide of human ENaC in a strategic hijack of host proteolytic machinery

2020-04-30 | Preprint
DOI: 10.1101/2020.04.29.069476
Contributors: Praveen Anand; Arjun Puranik; Murali Aravamudan; AJ Venkatakrishnan; Venky Soundararajan
Source: check_circle
Crossref
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