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Scopus Author ID: 6701315459

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United Kingdom

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Employment (3)

University of Birmingham: Birmingham, Birmingham, GB

2000-01-01 to present | Reader in Structural Biology (School of Biosciences)
Employment
Source: Self-asserted source
Klaus Fütterer

Washington University in St. Louis: MO, MO, US

1995-04-01 to 1999-12-31 | Research Associate (Department of Biochemistry and Molecular Biophysics)
Employment
Source: Self-asserted source
Klaus Fütterer

Australian National University: Canberra, ACT, AU

1994-04-01 to 1995-03-31 | Postdoctoral Fellow (Research School of Chemistry)
Employment
Source: Self-asserted source
Klaus Fütterer

Education and qualifications (2)

Technische Universität Berlin: Berlin, Berlin, DE

1989-07-01 to 1994-01-14 | Dr. rer. nat. (Fachbereich Bergbau und Geowissenschaften)
Education
Source: Self-asserted source
Klaus Fütterer

Karlsruher Institut für Technologie: Karlsruhe, Baden-Württemberg, DE

1984-04-01 to 1989-06-12 | Diplom-Physiker (Fakultät für Physik)
Education
Source: Self-asserted source
Klaus Fütterer

Works (50 of 70)

Items per page:
Page 1 of 2

Cryo-electron microscopy structure of the di-domain core of Mycobacterium tuberculosis polyketide synthase 13, essential for mycobacterial mycolic acid synthesis

Microbiology
2024-10-16 | Journal article
DOI: 10.1099/mic.0.001505
Contributors: Hannah E. Johnston; Sarah M. Batt; Alistair K. Brown; Christos G. Savva; Gurdyal S. Besra; Klaus Fütterer
Source: check_circle
Crossref

CryoEM structure of the di-domain core ofMycobacterium tuberculosispolyketide synthase 13, essential for mycobacterial mycolic acid synthesis

2024-04-28 | Preprint
DOI: 10.1101/2024.04.28.591520
Contributors: Hannah E Johnston; Sarah M Batt; Alistair K Brown; Christos G Savva; Gurdyal S Besra; Klaus Fütterer
Source: check_circle
Crossref

Crystal structure of the TreS:Pep2 complex, initiating α-glucan synthesis in the GlgE pathway of mycobacteria

Journal of Biological Chemistry
2019-05-03 | Journal article
DOI: 10.1074/jbc.RA118.004297
Contributors: Ali A. Kermani; Rana Roy; Chai Gopalasingam; Klaudia I. Kocurek; Trushar R. Patel; Luke J. Alderwick; Gurdyal S. Besra; Klaus Fütterer
Source: check_circle
Crossref

Crystal structure of Mycobacterium tuberculosis FadB2 implicated in mycobacterial β-oxidation

2019-01-08 | Journal article
DOI: 10.1107/s2059798318017242
Part of ISSN: 2059-7983
Source: Self-asserted source
Klaus Fütterer

Novel insight into the reaction of nitro, nitroso and hydroxylamino benzothiazinones and of benzoxacinones with Mycobacterium tuberculosis DprE1

2018-09-07 | Journal article
DOI: 10.1038/s41598-018-31316-6
Part of ISSN: 2045-2322
Source: Self-asserted source
Klaus Fütterer

Determinants of the Inhibition of DprE1 and CYP2C9 by Antitubercular Thiophenes

2017-09-07 | Journal article
DOI: 10.1002/anie.201707324
Part of ISSN: 1433-7851
Source: Self-asserted source
Klaus Fütterer

Inhibiting mycobacterial tryptophan synthase by targeting the inter-subunit interface

Scientific Reports
2017-08-25 | Journal article
DOI: 10.1038/s41598-017-09642-y
Contributors: Katherine A. Abrahams; Jonathan A. G. Cox; Klaus Fütterer; Joaquín Rullas; Fátima Ortega-Muro; Nicholas J. Loman; Patrick J. Moynihan; Esther Pérez-Herrán; Elena Jiménez; Jorge Esquivias et al.
Source: check_circle
Crossref

Carbon Nanofibers Functionalized with Active Screen Plasma-Deposited Metal Nanoparticles for Electrical Energy Storage Devices

2017-07-12 | Journal article
DOI: 10.1021/acsami.7b05567
Part of ISSN: 1944-8244
Part of ISSN: 1944-8252
Source: Self-asserted source
Klaus Fütterer

Structural and functional analysis of the solute-binding protein UspC from Mycobacterium tuberculosis that is specific for amino sugars

Open Biology
2016-06 | Journal article
DOI: 10.1098/rsob.160105
Contributors: Elizabeth Fullam; Ivan Prokes; Klaus Fütterer; Gurdyal S. Besra
Source: check_circle
Crossref
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Preferred source (of 2)‎

THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria

Nat Microbiol.
2016-01-18 | Journal article
DOI: 10.1038/nmicrobiol.2015.6.
Source: Self-asserted source
Klaus Fütterer

Biochemical and structural characterization of mycobacterial aspartyl-tRNA synthetase AspS, a promising TB drug target

PLoS ONE
2014 | Journal article
DOI: 10.1371/journal.pone.0113568
EID:

2-s2.0-84915803426
Contributors: Gurcha, S.S.; Usha, V.; Cox, J.A.G.; Fütterer, K.; Abrahams, K.A.; Bhatt, A.; Alderwick, L.J.; Reynolds, R.C.; Loman, N.J.; Nataraj, V. et al.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Erratum: Identification of a small molecule with activity against drug-resistant and persistent tuberculosis (Proceedings of the National Academy of Sciences of the United States of America (2013) 27:110 (E2510-E2517))

Proceedings of the National Academy of Sciences of the United States of America
2013 | Journal article
DOI: 10.1073/pnas.1314629110
EID:

2-s2.0-84884666768
Contributors: Wang, F.; Sambandan, D.; Halder, R.; Wang, J.; Batt, S.M.; Weinrick, B.; Ahmad, I.; Yang, P.; Zhang, Y.; Kim, J. et al.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Identification of a small molecule with activity against drug-resistant and persistent tuberculosis

Proceedings of the National Academy of Sciences of the United States of America
2013 | Journal article
DOI: 10.1073/pnas.1309171110
EID:

2-s2.0-84879707160
Contributors: Wang, F.; Sambandan, D.; Halder, R.; Wang, J.; Batt, S.M.; Weinrick, B.; Ahmad, I.; Yang, P.; Zhang, Y.; Kim, J. et al.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Synthesis of α-glucan in mycobacteria involves a hetero-octameric complex of trehalose synthase TreS and Maltokinase Pep2

ACS chemical biology
2013-08-13 | Journal article
DOI: 10.1021/cb400508k
Source: Self-asserted source
Klaus Fütterer
grade
Preferred source (of 2)‎

Bacterial to Biogenesis Structure Lipoarabinomannan

Bacterial Glycomics: Current Research, Technology and Applications
2012 | Journal article
Source: Self-asserted source
Klaus Fütterer

Structural basis of inhibition of Mycobacterium tuberculosis DprE1 by benzothiazinone inhibitors

Proceedings of the National Academy of Sciences of the United States of America
2012 | Journal article
DOI: 10.1073/pnas.1205735109
EID:

2-s2.0-84863919677
Contributors: Batt, S.M.; Jabeen, T.; Bhowruth, V.; Quill, L.; Lund, P.A.; Eggeling, L.; Alderwick, L.J.; Fuẗterer, K.; Besra, G.S.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

The C-terminal domain of the arabinosyltransferase mycobacterium tuberculosis EmbC is a lectin-like carbohydrate binding module

PLoS Pathogens
2011 | Journal article
DOI: 10.1371/journal.ppat.1001299
EID:

2-s2.0-79952211396
Contributors: Alderwick, L.J.; Lloyd, G.S.; Ghadbane, H.; May, J.W.; Bhatt, A.; Eggeling, L.; Fütterer, K.; Besra, G.S.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Acceptor substrate discrimination in phosphatidyl-myo-inositol mannoside synthesis: Structural and mutational analysis of mannosyltransferase corynebacterium glutamicum PimB′

Journal of Biological Chemistry
2010 | Journal article
DOI: 10.1074/jbc.M110.165407
EID:

2-s2.0-78549234746
Contributors: Batt, S.M.; Jabeen, T.; Mishra, A.K.; Veerapen, N.; Krumbach, K.; Eggeling, L.; Besra, G.S.; Fütterer, K.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

CLEC-2 activates Syk through dimerization

Blood
2010 | Journal article
DOI: 10.1182/blood-2009-08-237834
EID:

2-s2.0-77951062027
Contributors: Hughes, C.E.; Pollitt, A.Y.; Mori, J.; Eble, J.A.; Tomlinson, M.G.; Hartwig, J.H.; O'Callaghan, C.A.; Fütterer, K.; Watson, S.P.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

The Staphylococcus aureus autoinducer-2 synthase LuxS is regulated by Ser/Thr phosphorylation

Journal of Bacteriology
2010 | Journal article
DOI: 10.1128/JB.00853-10
EID:

2-s2.0-78649361924
Contributors: Cluzel, M.-E.; Zanella-Cléon, I.; Cozzone, A.J.; Fütterer, K.; Duclos, B.; Molle, V.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Bacterial flagellar diversity and evolution: seek simplicity and distrust it?

Trends in Microbiology
2009 | Journal article
DOI: 10.1016/j.tim.2008.10.002
EID:

2-s2.0-58149302693
Contributors: Snyder, L.A.S.; Loman, N.J.; Fütterer, K.; Pallen, M.J.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Platensimycin activity against mycobacterial β-ketoacyl-ACP synthases

PLoS ONE
2009 | Journal article
DOI: 10.1371/journal.pone.0006306
EID:

2-s2.0-67650930400
Contributors: Brown, A.K.; Taylor, R.C.; Bhatt, A.; Fütterer, K.; Besra, G.S.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Structure of the diaminopimelate epimerase DapF from Mycobacterium tuberculosis

Acta Crystallographica Section D: Biological Crystallography
2009 | Journal article
DOI: 10.1107/S0907444909002522
EID:

2-s2.0-63149100467
Contributors: Usha, V.; Dover, L.G.; Roper, D.I.; Fütterer, K.; Besra, G.S.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

The Mycobacterium tuberculosis β-ketoacyl-acyl carrier protein synthase III activity is inhibited by phosphorylation on a single threonine residue

Journal of Biological Chemistry
2009 | Journal article
DOI: 10.1074/jbc.M806537200
EID:

2-s2.0-65249174626
Contributors: Veyron-Churlet, R.; Molle, V.; Taylor, R.C.; Brown, A.K.; Besra, G.S.; Zanella-Cléon, I.; Fütterer, K.; Kremer, L.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Differential specific radiation damage in the CuII-bound and PdII-bound forms of an α-helical foldamer: A case study of crystallographic phasing by RIP and SAD

Acta Crystallographica Section D: Biological Crystallography
2008 | Journal article
DOI: 10.1107/S0907444907065948
EID:

2-s2.0-40449113461
Contributors: Fütterer, K.; Ravelli, R.B.G.; White, S.A.; Nicoll, A.J.; Allemann, R.K.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Donor substrate recognition in the raffinose-bound E342A mutant of fructosyltransferase Bacillus subtilis levansucrase

BMC Structural Biology
2008 | Journal article
DOI: 10.1186/1472-6807-8-16
EID:

2-s2.0-41549120638
Contributors: Meng, G.; Fütterer, K.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

EmbR2, a structural homologue of EmbR, inhibits the Mycobacterium tuberculosis kinase/substrate pair PknH/EmbR

Biochemical Journal
2008 | Journal article
DOI: 10.1042/BJ20071384
EID:

2-s2.0-40449124718
Contributors: Molle, V.; Reynolds, R.C.; Alderwick, L.J.; Besra, G.S.; Cozzoime, A.J.; Fütterer, K.; Kremer, L.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Identification of the insulin-responsive tyrosine phosphorylation sites on IRSp53

European Journal of Cell Biology
2008 | Journal article
DOI: 10.1016/j.ejcb.2008.02.010
EID:

2-s2.0-49249085903
Contributors: Heung, M.-Y.; Visegrady, B.; Fütterer, K.; Machesky, L.M.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

"Wunder" F-BAR Domains: Going from Pits to Vesicles

Cell
2007 | Journal article
DOI: 10.1016/j.cell.2007.05.006
EID:

2-s2.0-34249005822
Contributors: Fütterer, K.; Machesky, L.M.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Dimerization of inositol monophosphatase Mycobacterium tuberculosis SuhB is not constitutive, but induced by binding of the activator Mg<sup>2+</sup>

BMC Structural Biology
2007 | Journal article
DOI: 10.1186/1472-6807-7-55
EID:

2-s2.0-36248997046
Contributors: Brown, A.K.; Meng, G.; Ghadbane, H.; Scott, D.J.; Dover, L.G.; Nigou, J.; Besra, G.S.; Fütterer, K.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Regulation of cell wall synthesis and growth

Current Molecular Medicine
2007 | Journal article
DOI: 10.2174/156652407780598601
EID:

2-s2.0-34248673209
Contributors: Dover, L.G.; Alderwick, L.J.; Brown, A.K.; Futterer, K.; Besra, G.S.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Replacement of the essential Dictyostelium Arp2 gene by its Entamoeba homologue using parasexual genetics

BMC Genetics
2007 | Journal article
DOI: 10.1186/1471-2156-8-28
EID:

2-s2.0-34447282292
Contributors: Zaki, M.; King, J.; Fütterer, K.; Insall, R.H.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Structure of Mycobacterium tuberculosis mtFabD, a malonyl-CoA:acyl carrier protein transacylase (MCAT)

Acta Crystallographica Section F: Structural Biology and Crystallization Communications
2007 | Journal article
DOI: 10.1107/S1744309107042455
EID:

2-s2.0-34848914787
Contributors: Ghadbane, H.; Brown, A.K.; Kremer, L.; Besra, G.S.; Fütterer, K.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

“Wunder” F-BAR domains: going from pits to vesicles

Cell
2007 | Journal article
Source: Self-asserted source
Klaus Fütterer

Designed high affinity Cu<sup>2+</sup>-binding α-helical foldamer

Journal of the American Chemical Society
2006 | Journal article
DOI: 10.1021/ja061513u
EID:

2-s2.0-33746063213
Contributors: Nicoll, A.J.; Miller, D.J.; Fütterer, K.; Ravelli, R.; Allemann, R.K.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Molecular structure of EmbR, a response element of Ser/Thr kinase signaling in Mycobacterium tuberculosis

Proceedings of the National Academy of Sciences of the United States of America
2006 | Journal article
DOI: 10.1073/pnas.0507766103
EID:

2-s2.0-33644500423
Contributors: Alderwick, L.J.; Molle, V.; Kremer, L.; Cozzone, A.J.; Dafforn, T.R.; Besra, G.S.; Fütterer, K.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Anti-bacterial compounds directed against pilus biogenesis, adhesion and activity; co-crystals of pilus subunits and methods of use thereof

2006-05 | Other
Source: Self-asserted source
Klaus Fütterer

Control of protein conformation through high affinity copper binding

2005 | Journal article
Source: Self-asserted source
Klaus Fütterer

Structural basis of filopodia formation induced by the IRSp53/MIM homology domain of human IRSp53

EMBO Journal
2005 | Journal article
DOI: 10.1038/sj.emboj.7600535
EID:

2-s2.0-13444291116
Contributors: Millard, T.H.; Bompard, G.; Heung, M.Y.; Dafforn, T.R.; Scott, D.J.; Machesky, L.M.; Fütterer, K.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Crystal structure of the TetR/CamR family repressor Mycobacterium tuberculosis EthR implicated in ethionamide resistance

Journal of Molecular Biology
2004 | Journal article
DOI: 10.1016/j.jmb.2004.06.003
EID:

2-s2.0-3242812945
Contributors: Dover, L.G.; Corsino, P.E.; Daniels, I.R.; Cocklin, S.L.; Tatituri, V.; Besra, G.S.; Fütterer, K.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

The C-terminal domain of full-length E. coli SSB is disordered even when bound to DNA

Protein Science
2004 | Journal article
DOI: 10.1110/ps.04661904
EID:

2-s2.0-3042625942
Contributors: Savvides, S.N.; Raghunathan, S.; Fütterer, K.; Kozlov, A.G.; Lohman, T.M.; Waksman, G.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

The Structure of Mycobacterium tuberculosis MPT51 (FbpC1) Defines a New Family of Non-catalytic α/β Hydrolases

Journal of Molecular Biology
2004 | Journal article
DOI: 10.1016/j.jmb.2003.11.001
EID:

2-s2.0-0346996696
Contributors: Wilson, R.A.; Maughan, W.N.; Kremer, L.; Besra, G.S.; Fütterer, K.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Crystallization and preliminary X-ray diffraction data of Mycobacterium tuberculosis FbpC1 (Rv3803c)

Acta Crystallographica - Section D Biological Crystallography
2003 | Journal article
DOI: 10.1107/S0907444903020456
EID:

2-s2.0-0347812950
Contributors: Wilson, R.A.; Rai, S.; Maughan, W.N.; Kremer, L.; Kariuki, B.M.; Harris, K.D.M.; Wagner, T.; Besra, G.S.; Fütterer, K.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Erratum: Identification and characterisation of a novel human isoform of Arp2/3 complex subunit p16-ARC/ARPC5 (Cell Motility and the Cytoskeleton (2003) 54 (81-90))

Cell Motility and the Cytoskeleton
2003 | Journal article
DOI: 10.1002/cm.10104
EID:

2-s2.0-0037372891
Contributors: Millard, T.H.; Behrendt, B.; Launay, S.; Fütterer, K.; Machesky, L.M.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Identification and characterisation of a novel human isoform of Arp2/3 complex subunit p16-ARC/ARPC5

Cell Motility and the Cytoskeleton
2003 | Journal article
DOI: 10.1002/cm.10087
EID:

2-s2.0-0037215933
Contributors: Millard, T.H.; Behrendt, B.; Launay, S.; Fütterer, K.; Machesky, L.M.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Structural framework of fructosyl transfer in Bacillus subtilis levansucrase

Nature Structural Biology
2003 | Journal article
DOI: 10.1038/nsb974
EID:

2-s2.0-0242490546
Contributors: Meng, G.; Fütterer, K.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Tetratricopeptide-like repeats in type-III-secretion chaperones and regulators

FEMS Microbiology Letters
2003 | Journal article
DOI: 10.1016/S0378-1097(03)00344-6
EID:

2-s2.0-0038546513
Contributors: Pallen, M.J.; Francis, M.S.; Fütterer, K.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

9 Biology and enzymology of protein N-myristoylation

Enzymes
2001 | Book
DOI: 10.1016/S1874-6047(01)80022-6
EID:

2-s2.0-0141828378
Contributors: Bhatnagar, R.S.; Ashrafi, K.; Fütterer, K.; Waksman, G.; Gordon, J.I.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

Crystallographic phasing of myristoyl-CoA-protein N-myristoyltransferase using an iodinated analog of myristoyl-CoA

Acta Crystallographica Section D: Biological Crystallography
2001 | Journal article
DOI: 10.1107/S090744490100052X
EID:

2-s2.0-0035093084
Contributors: Fütterer, K.; Murray, C.L.; Bhatnagar, R.S.; Gokel, G.W.; Gordon, J.I.; Waksman, G.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier

The "open" and "closed" structures of the type-C inorganic pyrophosphatases from Bacillus subtilis and Streptococcus gordonii

Journal of Molecular Biology
2001 | Journal article
DOI: 10.1006/jmbi.2001.5070
EID:

2-s2.0-0035798394
Contributors: Ahn, S.; Milner, A.J.; Fütterer, K.; Konopka, M.; Ilias, M.; Young, T.W.; White, S.A.
Source: Self-asserted source
Klaus Fütterer via Scopus - Elsevier
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