Personal information

Emails & domains

Verified email addresses

Verified email domains

Websites & social links

Stem cell biology, developmental cancer and immunotherapy laboratory
Department of Physiological Sciences, University of Barcelona

Other IDs

Scopus Author ID: 57210200956
ResearcherID: AAA-9071-2019

Keywords

Aneuploidy, chromosomal instability, Centromere, Cell division, Acute lymphoblastic leukaemia

Countries

Spain, United Kingdom

Activities

Collapse all

Employment (4)

University of Barcelona: Barcelona, ES

2024-11-25 to present | Assistant Professor (Physiological Sciences)
Employment
Source: Self-asserted source
Oscar Molina

Josep Carreras Leukaemia Research Institute: Barcelona, Catalunya, ES

2017-01-04 to 2024-11-24 | Postdoctoral Researcher (Department of Biomedicine, School of Medicine UB)
Employment
Source: Self-asserted source
Oscar Molina

University of Edinburgh: Edinburgh, Edinburgh, GB

2012-02-01 to 2016-12-21 | Postdoctoral Researcher (Wellcome Trust Centre for Cell Biology)
Employment
Source: Self-asserted source
Oscar Molina

Universitat Autònoma de Barcelona: Barcelona, Catalunya, ES

2005-04-01 to 2011-12-21 | PhD Student (Cell Biology, Physiology and Immunology)
Employment
Source: Self-asserted source
Oscar Molina

Education and qualifications (2)

Autonomous University of Barcelona: Bellaterra, Catalonia, ES

2006-05-01 to 2011-12-21 | PhD (Department of Cell Biology, Physiology and Immunology)
Education
Source: Self-asserted source
Oscar Molina

Autonomous University of Barcelona: Bellaterra, Catalonia, ES

2001-07 to 2005-02 | BSc. Biology, Genetics and Cell Biology
Qualification
Source: Self-asserted source
Oscar Molina

Professional activities (1)

Autonomous University of Barcelona: Cerdanyola del Vallès, ES

2023-09-14 to 2026-09-14 | Associated lecturer in Cell Biology (Cell Biology, phisiology and immunology. )
Invited position
Source: Self-asserted source
Oscar Molina

Funding (6)

Chromosome instability and leukemia-initiating stem cell-driven pathophysiology of aneuploid childhood B-cell acute lymphoblastic leukemia

2024-01 to 2026-12 | Grant
Deutsche José Carreras Leukämie-Stiftung (Munich, DE)
GRANT_NUMBER:

DJCLS15 R/2023
Source: Self-asserted source
Oscar Molina

Clonal heterogeneity and leukemia-initiating stem cell-driven pathophysiology of aneuploid childhood B cell acute lymphoblastic leukemia

2024-01 to 2026-12 | Grant
Ministerio de Ciencia e Innovación (Madrid, ES)
GRANT_NUMBER:

PID2022-142966OB-I00
Source: Self-asserted source
Oscar Molina

Investigador AECC

2021-12 to 2025-12 | Contract
Fundación Científica Asociación Española Contra el Cáncer (Barcelona, ES)
GRANT_NUMBER: INVES211226MOLI
Source: Self-asserted source
Oscar Molina

Post-doctoral programme Beatriu de Pinos

2017-09 to 2019-08 | Contract
European Commission (Brussels, BE)
URL: https://grants.uberresearch.com/501100000780/96398/Post-doctoral-programme-Beatriu-de-Pinos
GRANT_NUMBER: grant.246535
Source: Self-asserted source
Oscar Molina
grade
Preferred source (of 2)‎

Lady Tata International award for research on Leukemia

2017-08 to 2018-01 | Award
Lady Tata Memorial Trust (London, GB)
Source: Self-asserted source
Oscar Molina

EMBO Long-Term postdoctoral fellowship

2013-01 to 2014-12 | Contract
European Molecular Biology Organization (Heidelberg, DE)
GRANT_NUMBER:

ALTF-453-2012
Source: Self-asserted source
Oscar Molina

Works (32)

Susceptibility of Simuliidae (Diptera) larvae to a new Bti-based solid formulation in Cascavel, Brazil

Zoologia (Curitiba)
2025 | Journal article
DOI: 10.1590/s1984-4689.v42.e24020
Contributors: Paula C. Lis; Luis F.A. Alves; João A.C. Zequi; Priscilla de F. Cardoso; Gislayne T. Vilas-Bôas; Francisco A. Marques; Renan R. Schorr; Itamar F. Andreazza; Óscar S. Molina
Source: check_circle
Crossref

Backtracking NOM1::ETV6 fusion to neonatal pathogenesis of t(7;12) (q36;p13) infant AML

Leukemia
2024-08 | Journal article
DOI: 10.1038/s41375-024-02293-9
Contributors: Pablo Bousquets-Muñoz; Oscar Molina; Ignacio Varela; Ángel Álvarez-Eguiluz; Javier Fernández-Mateos; Ana Gómez; Elena G. Sánchez; Milagros Balbín; David Ruano; Manuel Ramírez-Orellana et al.
Source: check_circle
Crossref

Integrative single‐cell expression and functional studies unravels a sensitization to cytarabine‐based chemotherapy through HIF pathway inhibition in AML leukemia stem cells

HemaSphere
2024-02 | Journal article
DOI: 10.1002/hem3.45
Contributors: Talia Velasco‐Hernandez; Juan L. Trincado; Meritxell Vinyoles; Adria Closa; Alba Martínez‐Moreno; Francisco Gutiérrez‐Agüera; Oscar Molina; Virginia C. Rodríguez‐Cortez; Pau Ximeno‐Parpal; Narcís Fernández‐Fuentes et al.
Source: check_circle
Crossref

Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression

EMBO Molecular Medicine
2023-12-15 | Journal article
DOI: 10.1038/s44321-023-00006-w
Contributors: Oscar Molina; Carmen Ortega-Sabater; Namitha Thampi; Narcís Fernández-Fuentes; Mercedes Guerrero-Murillo; Alba Martínez-Moreno; Meritxell Vinyoles; Talía Velasco-Hernández; Clara Bueno; Juan L Trincado et al.
Source: check_circle
Crossref

A human genome editing–based MLL::AF4 ALL model recapitulates key cellular and molecular leukemogenic features

Blood
2023-11-16 | Journal article
DOI: 10.1182/blood.2023020858
Contributors: Clara Bueno; Raul Torres-Ruiz; Talia Velasco-Hernandez; Oscar Molina; Paolo Petazzi; Alba Martinez; Virginia Rodriguez; Meritxell Vinyoles; Sandra Cantilena; Owen Williams et al.
Source: check_circle
Crossref

Low input capture Hi-C (liCHi-C) identifies promoter-enhancer interactions at high-resolution

Nature Communications
2023-01-17 | Journal article
DOI: 10.1038/s41467-023-35911-8
Contributors: Laureano Tomás-Daza; Llorenç Rovirosa; Paula López-Martí; Andrea Nieto-Aliseda; François Serra; Ainoa Planas-Riverola; Oscar Molina; Rebecca McDonald; Cedric Ghevaert; Esther Cuatrecasas et al.
Source: check_circle
Crossref

Clonal heterogeneity and rates of specific chromosome gains are risk predictors in childhood high-hyperdiploid B-cell acute lymphoblastic leukemia.

Molecular oncology
2022-06 | Journal article
DOI: 10.1002/1878-0261.13276
PMID: 35726693
Contributors: Ramos-Muntada M; Trincado JL; Blanco J; Bueno C; Rodríguez-Cortez VC; Bataller A; López-Millán B; Schwab C; Ortega M; Velasco P et al.
Source: Self-asserted source
Oscar Molina via Europe PubMed Central

KMT2A-CBL rearrangements in acute leukemias: clinical characteristics and genetic breakpoints

Blood Advances
2021-12-28 | Journal article
DOI: 10.1182/bloodadvances.2021005736
Contributors: Alex Bataller; Francesca Guijarro; Aurélie Caye-Eude; Marion Strullu; Arthur Sterin; Oscar Molina; Patrice Chevallier; Marketa Zaliova; Jan Zuna; Pablo Mozas et al.
Source: check_circle
Crossref

Near-Haploidy and Low-Hypodiploidy in B-Cell Acute Lymphoblastic Leukemia: When Less Is Too Much

Cancers
2021-12-22 | Journal article
DOI: 10.3390/cancers14010032
Contributors: Oscar Molina; Alex Bataller; Namitha Thampi; Jordi Ribera; Isabel Granada; Pablo Velasco; José Luis Fuster; Pablo Menéndez
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Engraftment characterization of risk-stratified AML in NSGS mice

Blood Advances
2021-12-14 | Journal article
DOI: 10.1182/bloodadvances.2020003958
Contributors: Rafael Díaz de la Guardia; Talía Velasco-Hernandez; Francisco Gutiérrez-Agüera; Heleia Roca-Ho; Oscar Molina; Cesar Nombela-Arrieta; Alex Bataller; Jose Luis Fuster; Eduardo Anguita; Susana Vives et al.
Source: check_circle
Crossref

The insecticides permethrin and chlorpyriphos show limited genotoxicity and no leukemogenic potential in human and murine hematopoietic stem progenitor cells.

Haematologica
2021-10 | Journal article
DOI: 10.3324/haematol.2021.279047
PMID: 34706497
Contributors: Rodriguez-Cortez VC; Navarrete-Meneses MP; Molina O; Velasco-Hernandez T; Gonzalez J; Romecin P; Gutierrez-Aguera F; Roca-Ho H; Vinyoles M; Kowarz E et al.
Source: Self-asserted source
Oscar Molina via Europe PubMed Central

A novel and efficient tandem CD19- and CD22-directed CAR for B cell ALL.

Molecular therapy : the journal of the American Society of Gene Therapy
2021-09 | Journal article
DOI: 10.1016/j.ymthe.2021.08.033
PMID: 34478871
Contributors: Zanetti SR; Velasco-Hernandez T; Gutierrez-Agüera F; Díaz VM; Romecín PA; Roca-Ho H; Sánchez-Martínez D; Tirado N; Baroni ML; Petazzi P et al.
Source: Self-asserted source
Oscar Molina via Europe PubMed Central

Aneuploidy in Cancer: Lessons from Acute Lymphoblastic Leukemia.

Trends in cancer
2020-09-17 | Journal article
DOI: 10.1016/j.trecan.2020.08.008
PMID: 32952102
Source: Self-asserted source
Oscar Molina

Efficient elimination of primary B-ALL cells in vitro and in vivo using a novel 4-1BB-based CAR targeting a membrane-distal CD22 epitope.

Journal for immunotherapy of cancer
2020-08 | Journal article
DOI: 10.1136/jitc-2020-000896
PMID: 32788237
PMC: PMC7422657
Contributors: Velasco-Hernandez T; Zanetti SR; Roca-Ho H; Gutierrez-Aguera F; Petazzi P; Sánchez-Martínez D; Molina O; Baroni ML; Fuster JL; Ballerini P et al.
Source: Self-asserted source
Oscar Molina via Europe PubMed Central

Impaired Condensin Complex and Aurora B kinase underlie mitotic and chromosomal defects in hyperdiploid B-cell ALL

Blood
2020-04-22 | Journal article
DOI: 10.1182/blood.2019002538
Contributors: Oscar Molina; Meritxell Vinyoles; Isabel Granada; Heleia Roca-Ho; Francisco Gutierrez-Agüera; Luis Valledor; Carlos Manuel López-López; Pablo Rodríguez-González; Juan Luis Trincado; Sofía Tirados-Menéndez et al.
Source: check_circle
Crossref

CD133-directed CAR T-cells for MLL leukemia: on-target, off-tumor myeloablative toxicity.

Leukemia
2019-02-18 | Journal article
DOI: 10.1038/s41375-019-0418-8
PMID: 30778134
Source: Self-asserted source
Oscar Molina
grade
Preferred source (of 2)‎

NG2 antigen is a therapeutic target for MLL-rearranged B-cell acute lymphoblastic leukemia.

Leukemia
2019-01-11 | Journal article
DOI: 10.1038/s41375-018-0353-0
PMID: 30635633
Source: Self-asserted source
Oscar Molina
grade
Preferred source (of 2)‎

Human Artificial Chromosome with Regulated Centromere: A Tool for Genome and Cancer Studies

ACS Synthetic Biology
2018-09-21 | Journal article
DOI: 10.1021/acssynbio.8b00230
Contributors: Natalay Kouprina; Nikolai Petrov; Oscar Molina; Mikhail Liskovykh; Elisa Pesenti; Jun-ichirou Ohzeki; Hiroshi Masumoto; William C. Earnshaw; Vladimir Larionov
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Generation of a Synthetic Human Chromosome with Two Centromeric Domains for Advanced Epigenetic Engineering Studies

ACS Synthetic Biology
2018-04-20 | Journal article
DOI: 10.1021/acssynbio.8b00018
Contributors: Elisa Pesenti; Natalay Kouprina; Mikhail Liskovykh; Joan Aurich-Costa; Vladimir Larionov; Hiroshi Masumoto; William C. Earnshaw; Oscar Molina
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

HP1α targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry

The EMBO Journal
2018-02 | Journal article
DOI: 10.15252/embj.201797677
Part of ISSN: 0261-4189
Contributors: Jan G Ruppert; Kumiko Samejima; Melpomeni Platani; Oscar Molina; Hiroshi Kimura; A Arockia Jeyaprakash; Shinya Ohta; William C Earnshaw
Source: Self-asserted source
Oscar Molina via Crossref Metadata Search
grade
Preferred source (of 2)‎

Using human artificial chromosomes to study centromere assembly and function

Chromosoma
2017-10-07 | Journal article
DOI: 10.1007/s00412-017-0633-x
Contributors: Oscar Molina; Natalay Kouprina; Hiroshi Masumoto; Vladimir Larionov; William C. Earnshaw
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Molecular basis for Cdk1-regulated timing of Mis18 complex assembly and CENP-A deposition.

EMBO reports
2017-04-04 | Journal article
DOI: 10.15252/embr.201643564
PMID: 28377371
PMC: PMC5452045
Source: Self-asserted source
Oscar Molina
grade
Preferred source (of 2)‎

PREditOR: a synthetic biology approach to removing heterochromatin from cells

Chromosome Research
2016-12-06 | Journal article
DOI: 10.1007/s10577-016-9539-3
Contributors: Oscar Molina; Mar Carmena; Isabella E. Maudlin; William C. Earnshaw
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Epigenetic engineering reveals a balance between histone modifications and transcription in kinetochore maintenance

Nature Communications
2016-11 | Journal article
DOI: 10.1038/ncomms13334
Part of ISSN: 2041-1723
Contributors: Oscar Molina; Giulia Vargiu; Maria Alba Abad; Alisa Zhiteneva; A. Arockia Jeyaprakash; Hiroshi Masumoto; Natalay Kouprina; Vladimir Larionov; William C. Earnshaw
Source: Self-asserted source
Oscar Molina via Crossref Metadata Search
grade
Preferred source (of 2)‎

3D-CLEM Reveals that a Major Portion of Mitotic Chromosomes Is Not Chromatin.

Molecular cell
2016-11-10 | Journal article
DOI: 10.1016/j.molcel.2016.10.009
PMID: 27840028
PMC: PMC5128728
Source: Self-asserted source
Oscar Molina
grade
Preferred source (of 2)‎

Deletions and duplications of the 22q11.2 region in spermatozoa from DiGeorge/velocardiofacial fathers

Molecular Cytogenetics
2014 | Journal article
DOI: 10.1186/s13039-014-0086-3
EID:

2-s2.0-84989306783
Contributors: Vergés, L.; Molina, Ò.; Geán, E.; Vidal, F.; Blanco, J.
Source: Self-asserted source
Oscar Molina via Scopus - Elsevier

Histone H4 Lys 20 Monomethylation of the CENP-A Nucleosome Is Essential for Kinetochore Assembly

Developmental Cell
2014 | Journal article
DOI: 10.1016/j.devcel.2014.05.001
EID:

2-s2.0-84904707415
Contributors: Hori, T.; Shang, W.-H.; Toyoda, A.; Misu, S.; Monma, N.; Ikeo, K.; Molina, O.; Vargiu, G.; Fujiyama, A.; Kimura, H. et al.
Source: Self-asserted source
Oscar Molina via Scopus - Elsevier

High rates of de novo 15q11q13 inversions in human spermatozoa

Molecular Cytogenetics
2012 | Journal article
DOI: 10.1186/1755-8166-5-11
EID:

2-s2.0-84856582662
Contributors: Molina, O.; Anton, E.; Vidal, F.; Blanco, J.
Source: Self-asserted source
Oscar Molina via Scopus - Elsevier

High-resolution fish on DNA fibers for low-copy repeats genome architecture studies

Genomics
2012 | Journal article
DOI: 10.1016/j.ygeno.2012.08.007
EID:

2-s2.0-84869861891
Contributors: Molina, O.; Blanco, J.; Anton, E.; Vidal, F.; Volpi, E.V.
Source: Self-asserted source
Oscar Molina via Scopus - Elsevier

Sperm rates of 7q11.23, 15q11q13 and 22q11.2 deletions and duplications: A FISH approach

Human Genetics
2011 | Journal article
DOI: 10.1007/s00439-010-0894-4
EID:

2-s2.0-78651244291
Contributors: Molina, O.; Anton, E.; Vidal, F.; Blanco, J.
Source: Self-asserted source
Oscar Molina via Scopus - Elsevier

Deletions and duplications of the 15q11-q13 region in spermatozoa from Prader-Willi syndrome fathers

Molecular Human Reproduction
2010 | Journal article
DOI: 10.1093/molehr/gaq005
EID:

2-s2.0-77954049435
Contributors: Molina, O.; Blanco, J.; Vidal, F.
Source: Self-asserted source
Oscar Molina via Scopus - Elsevier

FISH on sperm: spot-counting to stop counting? Not yet

Fertility and Sterility
2009 | Journal article
DOI: 10.1016/j.fertnstert.2008.07.1779
EID:

2-s2.0-70349454119
Contributors: Molina, O.; Sarrate, Z.; Vidal, F.; Blanco, J.
Source: Self-asserted source
Oscar Molina via Scopus - Elsevier

Peer review (8 reviews for 6 publications/grants)

Review activity for Cell death and disease. (1)
Review activity for Cellular and molecular life sciences (1)
Review activity for Cellular and molecular life sciences (1)
Review activity for Leukemia (3)
Review activity for Nature communications (1)
Review activity for PloS one. (1)
How many people are using ORCID?