Personal information

Countries

Canada, United States, India, Portugal

Biography

I am a molecular and structural biologist investigating protein structures and cellular pathways regulated by innate immune proteins. During my PhD, I used cell biology and different biophysical techniques for protein characterization. I have significant experience in cloning, expression and purification of proteins. Currently using cryo-electron microscopy to obtain high-resolution protein structures.

Activities

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Employment (4)

Princeton University: Princeton, NJ, US

2021-06-01 to 2023-05-31 | Postdoctoral Research Associate (Molecular Biology)
Employment
Source: Self-asserted source
Amit Koul

University of Manitoba: Winnipeg, MB, CA

2014-05-01 to 2020-10-20 | Teaching Assistant (Chemistry)
Employment
Source: Self-asserted source
Amit Koul

Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica: Oeiras, Lisboa, PT

2011-09-01 to 2012-05-31 | Research Assistant (Raman Spectrsocopy Laboratory)
Employment
Source: Self-asserted source
Amit Koul

Universidade Nova de Lisboa Instituto de Tecnologia Química e Biológica: Oeiras, Lisboa, PT

2010-10-01 to 2011-03-31 | Trainee (Biological Chemistry)
Employment
Source: Self-asserted source
Amit Koul

Education and qualifications (3)

University of Manitoba: Winnipeg, Manitoba, CA

2014-05-01 to 2020-10-20 | PhD (Chemistry)
Education
Source: Self-asserted source
Amit Koul

Bangalore University: Bangalore, Karnataka, IN

2008-08-01 to 2010-08-01 | Master of Science Biotechnology (Biotechnology)
Education
Source: Self-asserted source
Amit Koul

Bangalore University: Bengaluru, Karnataka, IN

2002-06-01 to 2005-06-01 | Bachelor of science Biotechnology (Biotechnology)
Education
Source: Self-asserted source
Amit Koul

Funding (3)

Advancement of Hyperimmune candidates against select pathogens from the Antibody Therapeutics Business Unit’s Lead Generation Program

Source: Self-asserted source
Amit Koul

Impact of double-stranded RNA characteristics on the activation of human 2′–5′-oligoadenylate synthetase 2 (OAS2)

2015-09 to 2018-09 | Award
University of Manitoba (Winnipeg, MB, CA)
Source: Self-asserted source
Amit Koul

Electron transfer dynamic of R. marinus caa3 cytochrome C domains

2011-09 to 2012-05 | Award
Instituto de Tecnologia Química e Biológica (Oeiras, Lisbon, PT)
Source: Self-asserted source
Amit Koul

Works (7)

Distinct domain organization and diversity of 2′-5′-oligoadenylate synthetases

Biochemistry and Cell Biology
2024-08-01 | Journal article
DOI: 10.1139/bcb-2023-0369
Contributors: Amit Koul; Lok Tin Hui; Nikhat Lubna; Sean A. McKenna
Source: check_circle
Crossref

Mathematical modelling of OAS2 activation by dsRNA and effects of dsRNA lengths

AIMS Mathematics
2021 | Journal article
DOI: 10.3934/math.2021351
Part of ISSN: 2473-6988
Source: Self-asserted source
Amit Koul

Structural and Hydrodynamic Characterization of Dimeric Human Oligoadenylate Synthetase 2

Biophysical Journal
2020-06 | Journal article
DOI: 10.1016/j.bpj.2020.04.025
Contributors: Amit Koul; Danielle Gemmill; Nikhat Lubna; Markus Meier; Natalie Krahn; Evan P. Booy; Jörg Stetefeld; Trushar R. Patel; Sean A. McKenna
Source: check_circle
Crossref

Impact of double-stranded RNA characteristics on the activation of human 2′–5′-oligoadenylate synthetase 2 (OAS2)

Biochemistry and Cell Biology
2020-02 | Journal article
DOI: 10.1139/bcb-2019-0060
Part of ISSN: 0829-8211
Part of ISSN: 1208-6002
Source: Self-asserted source
Amit Koul

The long non-coding RNA BC200 (BCYRN1) is critical for cancer cell survival and proliferation

Molecular Cancer
2017-12 | Journal article
DOI: 10.1186/s12943-017-0679-7
Part of ISSN: 1476-4598
Source: Self-asserted source
Amit Koul

Structural studies of RNA-protein complexes: A hybrid approach involving hydrodynamics, scattering, and computational methods

Methods
2017-04 | Journal article
DOI: 10.1016/j.ymeth.2016.12.002
Part of ISSN: 1046-2023
Source: Self-asserted source
Amit Koul

Characterization of the termini of the West Nile virus genome and their interactions with the small isoform of the 2′ 5′-oligoadenylate synthetase family

Journal of Structural Biology
2015-05 | Journal article
DOI: 10.1016/j.jsb.2015.04.005
Part of ISSN: 1047-8477
Source: Self-asserted source
Amit Koul

Peer review (8 reviews for 1 publication/grant)

Review activity for STAR protocols. (8)
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