Mohammad Najlah (0000-0001-7670-2859)

Personal information

Biography

Mohammad's research interests focus on the fabrication of multifunctional nanomedicines for drug delivery application. He has excellent experience of higher education as a teacher, researcher, external examiner and manager.
Mohammad took a pharmacy degree followed by postgraduate diploma (Industrial Pharmacy) at Damascus University and worked as a community pharmacist. He obtained his PhD (2007) from the University of Manchester, focusing on the ‘development of nano-medicines based on dendrimer prodrugs’. This research was continued at the University of Central Lancashire (UCLan) where he worked as a research fellow. During that period, he also contributed in founding of the School of Pharmacy and Biomedical Sciences. Administrative Affairs until the end of 2013.

Since joining Anglia Ruskin University, Mohammad has been instrumental in developing the SuperLabs Complex including the Pharmaceutical Research Lab, the establishment of new undergraduate and postgraduate programmes and leading the Pharmaceutical Research Group.
Mohammad is a Fellow of the Royal Society of Chemistry and external examiner for a number of UK institutions. He has supervised several PhD students to completion, is a regular reviewer for many international pharmaceutical and chemistry journals and has active research collaborations in several UK and International Universities.

Research interests
Development of Nano-Enabled Drug Carriers to Overcome Pan-Chemoresistance of Cancer Stem(-like) Cells
Engineering novel nanomaterials, polymeric prodrugs/conjugates and polymeric nano-particulates for drug delivery applications such as enhancing water solubility or/and overcoming the P-glycoprotein drug efflux transporter
Design and development of pharmaceutical carriers for pulmonary drug delivery
Using laser skin resurfacing to improve the permeability of drugs across the skin
Colloidal formulations (aerosols, nanoemulsions and nanodispersions)
Clinical pharmaceutics

Activities

Collapse all

Anglia Ruskin University: Chelmsford, Essex, GB

2021-08-01 to present | Professor of Pharmaceutics & Nanomedicine (School of Allied Health )

Employment

Mohammad Najlah

https://orcid.org/0000-0001-7670-2859

Personal information

Emails & domains

Verified email domains

Websites & social links

Other IDs

Countries

Biography

Activities

Employment (5)

Anglia Ruskin University: Chelmsford, Essex, GB

Anglia Ruskin University, School of Allied Health: Chelmsford, Essex, GB

Anglia Ruskin University, Faculty of Medical Science: Chelmsford, Essex, GB

Anglia Ruskin University, Faculty of Medical Science : Chelmsford, Essex, GB

Anglia Ruskin University: Chelmsford, Essex, GB

Education and qualifications (4)

University of Central Lancashire: Preston, Lancashire, GB

University of Manchester: Manchester, Manchester, GB

Damascus University: Damascus, SY

Damascus University: Damascus, SY

Professional activities (3)

Royal Society of Chemistry: London, London, GB

Higher Education Academy: London, GB

Controlled Release Society: Mount Laurel, US

Funding (4)

To develop and embed, the optimisation of processing techniques to suit specific applications for homogenisers

Open a new line of production for liposomal-based skincare formulations

Embedding the development, analysis and knowledge of liposomal formulation - both dry and liquid

Surfactant-Based Delivery Systems for The Treatment of Breast Cancer

Works (50 of 66)

PLGA-Nano-Encapsulated Disulfiram Inhibits Cancer Stem Cells and Targets Non-Small Cell Lung Cancer In Vitro and In Vivo

The Anticancer Activity of Monosaccharides: Perspectives and Outlooks

Exploring Disulfiram’s Anticancer Potential: PLGA Nano-Carriers for Prolonged Drug Delivery and Potential Improved Therapeutic Efficacy

Preparation and Characterisation of Zinc Diethyldithiocarbamate–Cyclodextrin Inclusion Complexes for Potential Lung Cancer Treatment

Data from PLGA–Nano-Encapsulated Disulfiram Inhibits Hypoxia-Induced NF-κB, Cancer Stem Cells, and Targets Glioblastoma <i>In Vitro</i> and <i>In Vivo</i>

Data from PLGA–Nano-Encapsulated Disulfiram Inhibits Hypoxia-Induced NF-κB, Cancer Stem Cells, and Targets Glioblastoma <i>In Vitro</i> and <i>In Vivo</i>

Supplementary Figure from PLGA–Nano-Encapsulated Disulfiram Inhibits Hypoxia-Induced NF-κB, Cancer Stem Cells, and Targets Glioblastoma <i>In Vitro</i> and <i>In Vivo</i>

Supplementary Figure from PLGA–Nano-Encapsulated Disulfiram Inhibits Hypoxia-Induced NF-κB, Cancer Stem Cells, and Targets Glioblastoma <i>In Vitro</i> and <i>In Vivo</i>

Supplementary Figure from PLGA–Nano-Encapsulated Disulfiram Inhibits Hypoxia-Induced NF-κB, Cancer Stem Cells, and Targets Glioblastoma <i>In Vitro</i> and <i>In Vivo</i>

Supplementary Figure from PLGA–Nano-Encapsulated Disulfiram Inhibits Hypoxia-Induced NF-κB, Cancer Stem Cells, and Targets Glioblastoma <i>In Vitro</i> and <i>In Vivo</i>

Amlexanox-loaded nanoliposomes showing enhanced anti-inflammatory activity in cultured macrophages: A potential formulation for treatment of oral aphthous stomatitis

Preparation and Characterization of Disulfiram and Beta Cyclodextrin Inclusion Complexes for Potential Application in the Treatment of SARS-CoV-2 via Nebulization

PLGA–Nano-Encapsulated Disulfiram Inhibits Hypoxia-Induced NF-κB, Cancer Stem Cells, and Targets Glioblastoma In Vitro and In Vivo

Scientific validation of three-dimensional stereophotogrammetry compared to the IGAIS clinical scale for assessing wrinkles and scars after laser treatment

Treatment of Scars with Laser-Assisted Delivery of Growth Factors and Vitamin C: A Comparative, Randomised, Double-blind, Early Clinical Trial

Comparative Study on the Outcome of Periorbital Wrinkles Treated with Laser-Assisted Delivery of Vitamin C or Vitamin C Plus Growth Factors: A Randomized, Double-blind, Clinical Trial

Drug Repurposing Supported by Nanotechnology: a Promising Strategy to Fight Cancer

Sunscreens Containing Cyclodextrin Inclusion Complexes for Enhanced Efficiency: A Strategy for Skin Cancer Prevention

Cyclodextrin Diethyldithiocarbamate Copper II Inclusion Complexes: A Promising Chemotherapeutic Delivery System against Chemoresistant Triple Negative Breast Cancer Cell Lines

Scientific Validation of Three-Dimensional Stereophotogrammetry Compared to the IGAIS Clinical Scale for Assessing Wrinkles and Scars after Laser Treatment

Carbon nanotubes drug delivery system for cancer treatment

Intelligent image-based colourimetric tests using machine learning framework for lateral flow assays

Letrozole-loaded nonionic surfactant vesicles prepared via a slurry-based proniosome technology: Formulation development and characterization

Proliposome powder or tablets for generating inhalable liposomes using a medical nebulizer

Taxane anticancer formulations: challenges and achievements

Development, characterization and stability evaluation of ciprofloxacin-loaded parenteral nutrition nanoemulsions.

Drink types unmask the health risks associated with alcohol intake - Prospective evidence from the general population.

Development of Injectable PEGylated Liposome Encapsulating Disulfiram for Colorectal Cancer Treatment

Development, characterisation and in vitro evaluation of disulfiram loaded PEGylated nanoparticles for breast cancer treatment

Development of long circulating PEGylated liposome of disulfiram for colorectal cancer therapy

The use of albumin solid dispersion to enhance the solubility of unionizable drugs

Spray-Dried Proliposome Microparticles for High-Performance Aerosol Delivery Using a Monodose Powder Inhaler.

In Vitro Evaluation of Third Generation PAMAM Dendrimer Conjugates

Development and characterisation of disulfiram-loaded PLGA nanoparticles for the treatment of non-small cell lung cancer

Efficient approach to enhance drug solubility by particle engineering of bovine serum albumin

Ethanol-based proliposome delivery systems of paclitaxel for in vitro application against brain cancer cells

Liposome Delivery Systems for Inhalation: A Critical Review Highlighting Formulation Issues and Anticancer Applications

Novel paclitaxel formulations solubilized by parenteral nutrition nanoemulsions for application against glioma cell lines

A simple approach to predict the stability of phospholipid vesicles to nebulization without performing aerosolization studies

Effect of non-cross-linked calcium on characteristics, swelling behaviour, drug release and mucoadhesiveness of calcium alginate beads

The cytotoxic mechanisms of disulfiram and copper(ii) in cancer cells

A facile approach to manufacturing non-ionic surfactant nanodipsersions using proniosome technology and high-pressure homogenization.

Stability of parenteral nanoemulsions loaded with paclitaxel: the influence of lipid phase composition, drug concentration and storage temperature.

PAMAM dendrimers as aerosol drug nanocarriers for pulmonary delivery via nebulization.

The effects of suspension particle size on the performance of air-jet, ultrasonic and vibrating-mesh nebulisers.

A study of the effects of sodium halides on the performance of air-jet and vibrating-mesh nebulizers

Delivery of paclitaxel across cellular barriers using a dendrimer-based nanocarrier

An Ethanol-Based Proliposome Technology for Enhanced Delivery and Improved “Respirability” of Antiasthma Aerosols Generated Using a Micropump Vibrating-Mesh Nebulizer

Dendrimer-Based Prodrugs: Synthesis and Biological Evaluation