Personal information

Websites & social links

ResearchGate profile
Scopus profile

Other IDs

Scopus Author ID: 22950014100
ResearcherID: M-3654-2015
SciProfiles: 1885456

Countries

France, Spain, United States

Activities

Collapse all

Employment (7)

Universitat de Lleida: Lleida, Catalunya, ES

2017-02-01 to present | Assistant Professor (Basic Medical Sciences)
Employment
Source: Self-asserted source
Fabien Delaspre

Institut de Recerca Biomèdica de Lleida: Lleida, ES

2015-07-14 to present | Research Fellow (Basic Medical Sciences)
Employment
Source: Self-asserted source
Fabien Delaspre

Johns Hopkins Medicine McKusick-Nathans Institute of Genetic Medicine: Baltimore, MD, US

2013-12-01 to 2015-06-30 | Research Fellow
Employment
Source: Self-asserted source
Fabien Delaspre

Johns Hopkins University School of Medicine: Baltimore, MD, US

2011-07-01 to 2013-11-30 | PostDoctoral fellow (Surgery)
Employment
Source: Self-asserted source
Fabien Delaspre

Institut Hospital del Mar d'Investigacions Mèdiques: Barcelona, Catalunya, ES

2006-03-20 to 2010-12-31 | PhD Student (Molecular mechanisms of tumorigenesis)
Employment
Source: Self-asserted source
Fabien Delaspre

Laboratoire des Interactions Plantes Micro-organismes: Castanet Tolosan, Midi-Pyrénées, FR

2005-11-01 to 2006-01-31 | Research Assistant (Julia Vorholt Group)
Employment
Source: Self-asserted source
Fabien Delaspre

Laboratoire d´Analyses médicales Escaret: Murat, Auvergne, FR

2001-07-01 to 2001-08-31 | Lab Technician trainee
Employment
Source: Self-asserted source
Fabien Delaspre

Education and qualifications (4)

Universidad Abierta de Cataluña: Barcelona, Catalunya, ES

2010-10 to 2012-06 | Master in City management and Urbanism
Education
Source: Self-asserted source
Fabien Delaspre

Universitat Pompeu Fabra: Barcelona, Catalunya, ES

2006-03-21 to 2011-02-04 | PhD Biomedicine
Education
Source: Self-asserted source
Fabien Delaspre

Université Paul Sabatier: Toulouse, Midi-Pyrénées, FR

2003-09-01 to 2005-06-30 | Master (Genetic - Microbiology)
Education
Source: Self-asserted source
Fabien Delaspre

Université Paul Sabatier: Toulouse, Midi-Pyrénées, FR

2000-09 to 2003-06 | Licence Biology
Education
Source: Self-asserted source
Fabien Delaspre

Professional activities (1)

Sociedad Española de Bioquímica y Biología Molecular: Madrid, ES

2015 to present
Membership
Source: Self-asserted source
Fabien Delaspre

Funding (2)

Juan de la cierva - Incorporación

2019-01 to 2021-06 | Contract
Ministerio de Ciencia e Innovación (Madrid, ES)
URL: http://www.ciencia.gob.es/portal/site/MICINN/menuitem.dbc68b34d11ccbd5d52ffeb801432ea0/?vgnextoid=8d50f4215103f510VgnVCM1000001d04140aRCRD
GRANT_NUMBER:

IJCI-2017-31347
Source: Self-asserted source
Fabien Delaspre

Maturation of Human Embryonic Stem Cells-Derived Pancreatic Progenitors into Insulin Producing Cells

2013-07 to 2015-06 | Salary award
Maryland Stem Cells Research Fund (Columbia, Maryland, US)
URL: http://www.mscrf.org/index.cfm
GRANT_NUMBER: 2013-MSCRFF-050
Source: Self-asserted source
Fabien Delaspre

Works (23)

Mitochondrial impairment, decreased sirtuin activity and protein acetylation in dorsal root ganglia in Friedreich Ataxia models

Cellular and Molecular Life Sciences
2024-12 | Journal article
DOI: 10.1007/s00018-023-05064-4
Contributors: Arabela Sanz-Alcázar; Elena Britti; Fabien Delaspre; Marta Medina-Carbonero; Maria Pazos-Gil; Jordi Tamarit; Joaquim Ros; Elisa Cabiscol
Source: check_circle
Crossref

Deciphering the ferroptosis pathways in dorsal root ganglia of Friedreich ataxia models. The role of LKB1/AMPK, KEAP1, and GSK3β in the impairment of the NRF2 response

Redox Biology
2024-10 | Journal article
DOI: 10.1016/j.redox.2024.103339
Contributors: Arabela Sanz-Alcázar; Marta Portillo-Carrasquer; Fabien Delaspre; Maria Pazos-Gil; Jordi Tamarit; Joaquim Ros; Elisa Cabiscol
Source: check_circle
Crossref

SYSTEMIC FRATAXIN DEFICIENCY CAUSES TISSUE-DEPENDENT IRON HOMEOSTASIS ALTERATIONS: IMPLICATIONS FOR FRIEDREICH ATAXIA

2024-07-06 | Preprint
DOI: 10.1101/2024.07.05.602088
Contributors: Maria Pazos-Gil; Marta Medina-Carbonero; Arabela Sanz-Alcázar; Marta Portillo-Carrasquer; Luiza Oliveira; Gonzalo Hernandez; Mayka Sánchez; Fabien Delaspre; Elisa Cabiscol; Joaquim Ros et al.
Source: check_circle
Crossref

Deficient mitochondrial respiration impairs sirtuin activity in dorsal root ganglia in Friedreich Ataxia mouse and cell models

2023-02-03 | Preprint
DOI: 10.1101/2023.02.01.526688
Contributors: Arabela Sanz-Alcázar; Elena Britti; Fabien Delaspre; Marta Medina-Carbonero; Maria Pazos-Gil; Jordi Tamarit; Joaquim Ros; Elisa Cabiscol
Source: check_circle
Crossref

Mice harboring the FXN I151F point mutation present decreased frataxin levels, a Friedreich Ataxia-like phenotype and mitochondrial alterations

FEBS Open Bio
2022 | Journal article
WOSUID: WOS:000821444601146
Contributors: Medina-Carbonero, M.; Sanz-Alcazar, A.; Pazos-Gil, M.; Britti, E.; Delaspre, F.; Cabiscol, E.; Ros, J.; Tamarit, J.
Source: check_circle
Web of Science Researcher Profile Sync

Mitochondrial dysfunction and redox alterations in cellular models and the I151F mouse model of Friedreich Ataxia: role of Sirt3

FEBS Open Bio
2022 | Journal article
WOSUID: WOS:000821444601175
Contributors: Sanz-Alcazar, A.; Britti, E.; Delaspre, F.; Medina-Carbonero, M.; Pazos-Gil, M.; Tamarit, J.; Ros, J.; Cabiscol, E.
Source: check_circle
Web of Science Researcher Profile Sync

Evolution of an Iron-Detoxifying Protein: Eukaryotic and Rickettsia Frataxins Contain a Conserved Site Which Is Not Present in Their Bacterial Homologues

International Journal of Molecular Sciences
2022-10-29 | Journal article
DOI: 10.3390/ijms232113151
Contributors: Rui Alves; Maria Pazos-Gil; Marta Medina-Carbonero; Arabela Sanz-Alcázar; Fabien Delaspre; Jordi Tamarit
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Mice harboring the FXN I151F pathological point mutation present decreased frataxin levels, a Friedreich ataxia-like phenotype, and mitochondrial alterations

Cellular and Molecular Life Sciences
2022-02 | Journal article
DOI: 10.1101/2021.04.05.438486
DOI: 10.1007/s00018-021-04100-5
Part of ISSN: 1420-682X
Part of ISSN: 1420-9071
Source: Self-asserted source
Fabien Delaspre
grade
Preferred source (of 2)‎

Mitochondrial iron and calcium homeostasis in Friedreich ataxia

IUBMB Life
2021-03 | Journal article
DOI: 10.1002/iub.2457
Contributors: Jordi Tamarit; Elena Britti; Fabien Delaspre; Marta Medina‐Carbonero; Arabela Sanz‐Alcázar; Elisa Cabiscol; Joaquim Ros
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

PPAR gamma agonist leriglitazone improves frataxin-loss impairments in cellular and animal models of Friedreich Ataxia

Neurobiology of Disease
2021-01 | Journal article
DOI: 10.1016/j.nbd.2020.105162
Contributors: Laura Rodríguez-Pascau; Elena Britti; Pablo Calap-Quintana; Yi Na Dong; Cristina Vergara; Fabien Delaspre; Marta Medina-Carbonero; Jordi Tamarit; Federico V. Pallardó; Pilar Gonzalez-Cabo et al.
Source: check_circle
Crossref

Calcitriol increases frataxin levels and restores altered markers in cell models of Friedreich Ataxia

[]
2020-04-10 | Preprint
DOI: 10.1042/bcj20200331
DOI: 10.1101/2020.04.09.034017
Part of ISSN: 0264-6021
Part of ISSN: 1470-8728
Source: Self-asserted source
Fabien Delaspre
grade
Preferred source (of 2)‎

Calpain-Inhibitors Protect Frataxin-Deficient Dorsal Root Ganglia Neurons from Loss of Mitochondrial Na+/Ca2+ Exchanger, NCLX, and Apoptosis.

Neurochemical research
2020-04-06 | Journal article
DOI: 10.1007/s11064-020-03020-3
PMID: 32249386
Source: Self-asserted source
Fabien Delaspre

Mitochondrial calcium signaling and Neurodegenerative Diseases

2018-11-16 | Journal article
DOI: 10.1042/NS20180061
Source: Self-asserted source
Fabien Delaspre

HIF-1α- Targeting Acriflavine Provides Long Term Survival and Radiological Tumor Response in Brain Cancer Therapy

Scientific Reports
2017-12 | Journal article
DOI: 10.1038/s41598-017-14990-w
Contributors: Antonella Mangraviti; Tula Raghavan; Francesco Volpin; Nicolas Skuli; David Gullotti; Jinyuan Zhou; Laura Asnaghi; Eric Sankey; Ann Liu; Yuan Wang et al.
Source: check_circle
Crossref

Mitochondrial pore opening and loss of Ca2+ exchanger NCLX levels occur after frataxin depletion.

Biochimica et biophysica acta
2017-12 | Journal article
DOI: 10.1016/j.bbadis.2017.12.005
PMID: 29223733
Source: Self-asserted source
Fabien Delaspre via Europe PubMed Central
grade
Preferred source (of 2)‎

Frataxin-deficient neurons and mice models of Friedreich ataxia are improved by TAT-MTScs-FXN treatment.

Journal of cellular and molecular medicine
2017-10 | Journal article
DOI: 10.1111/jcmm.13365
PMID: 28980774
Source: Self-asserted source
Fabien Delaspre via Europe PubMed Central
grade
Preferred source (of 2)‎

Sox9b is a mediator of retinoic acid signaling restricting endocrine progenitor differentiation.

2016-08 | Journal article
PMID: 27565026
Contributors: Huang W; Beer RL; Delaspre F; Wang G; Edelman HE; Park H; Azuma M; Parsons MJ
Source: Self-asserted source
Fabien Delaspre via Europe PubMed Central

Centroacinar cells are progenitors that contribute to endocrine pancreas regeneration.

2015-07 | Journal article
DOI: 10.2337/db15-0153
PMID: 26153247
Contributors: Delaspre F; Beer RL; Rovira M; Huang W; Wang G; Gee S; Vitery MD; Wheelan SJ; Parsons MJ
Source: Self-asserted source
Fabien Delaspre via Europe PubMed Central
grade
Preferred source (of 2)‎

First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass.

2015-07 | Journal article
DOI: 10.7554/eLife.08261
PMID: 26218223
Contributors: Wang G; Rajpurohit SK; Delaspre F; Walker SL; White DT; Ceasrine A; Kuruvilla R; Li RJ; Shim JS; Liu JO et al.
Source: Self-asserted source
Fabien Delaspre via Europe PubMed Central
grade
Preferred source (of 3)‎

Retinoic acid plays an evolutionarily conserved and biphasic role in pancreas development.

2014-10 | Journal article
DOI: 10.1016/j.ydbio.2014.07.021
PMID: 25127993
Contributors: Huang W; Wang G; Delaspre F; Vitery Mdel C; Beer RL; Parsons MJ
Source: Self-asserted source
Fabien Delaspre via Europe PubMed Central
grade
Preferred source (of 2)‎

Directed pancreatic acinar differentiation of mouse embryonic stem cells via embryonic signalling molecules and exocrine transcription factors.

2013 | Journal article
DOI: 10.1371/journal.pone.0054243
PMID: 23349836
PMC: PMC3547908
Contributors: Delaspre F; Massumi M; Salido M; Soria B; Ravassard P; Savatier P; Skoudy A
Source: Self-asserted source
Fabien Delaspre via Europe PubMed Central
grade
Preferred source (of 2)‎

Murine embryonic stem cell-derived pancreatic acinar cells recapitulate features of early pancreatic differentiation.

2008-10 | Journal article
DOI: 10.1053/j.gastro.2008.06.049
PMID: 18725222
PMC: PMC2586982
Contributors: Rovira M; Delaspre F; Massumi M; Serra SA; Valverde MA; Lloreta J; Dufresne M; Payré B; Konieczny SF; Savatier P et al.
Source: Self-asserted source
Fabien Delaspre via Europe PubMed Central
grade
Preferred source (of 2)‎

The Ralstonia solanacearum pathogenicity regulator HrpB induces 3-hydroxy-oxindole synthesis.

2007-10 | Journal article
DOI: 10.1073/pnas.0700782104
PMID: 17890323
PMC: PMC2000445
Contributors: Delaspre F; Nieto Peñalver CG; Saurel O; Kiefer P; Gras E; Milon A; Boucher C; Genin S; Vorholt JA
Source: Self-asserted source
Fabien Delaspre via Europe PubMed Central
grade
Preferred source (of 2)‎

Peer review (14 reviews for 7 publications/grants)

Review activity for Biomedicines. (2)
Review activity for Cells. (1)
Review activity for International journal of molecular sciences. (5)
Review activity for iScience. (2)
Review activity for Life. (2)
Review activity for Redox report. (1)
Review activity for Scientific reports. (1)
How many people are using ORCID?