Personal information

Emails & domains

Verified email domains

Websites & social links

University Profile
EQUATOR Collaboration

Other IDs

Scopus Author ID: 54880010400
Loop profile: 1431442

Keywords

Uveitis, Ophthalmology, Outcome Measures, Endpoints, Imaging

Countries

United Kingdom

Biography

Professor Alastair Denniston is a consultant ophthalmologist (eye specialist) at University Hospitals Birmingham NHS Foundation Trust, one of the UK’s largest acute healthcare organisations. His work focuses on use of health data research and the application of digital healthcare (including artificial intelligence) to improve patient care in the ‘real world’. The impact of his work has been recognised internationally with the award of 'Nature Medicine Notable Advances of the Year' in both 2019 and 2020.

Alastair leads a team committed to ensuring that the best innovation within the broad field of ‘artificial intelligence’ is translated safely, efficiently, equitably and inclusively to patients. This includes improving the design and reporting of clinical trials in this area (international standards CONSORT-AI and SPIRIT-AI), highlighting issues of representativeness including the risk of health data poverty; developing tools to support safe deployment (including validation datasets); and working with regulators and other stake-holder groups to support the best of these innovations right through the implementation pathway to routine patient care and public health.

Alastair has a particular interest in research and digital innovation to tackle sight-threatening disease. He is the Director of INSIGHT, the UK’s Health Data Research Hub for Eye Health which is focused on eye disease and its application to wider health, including diabetes and dementia (unlocking the power of ‘oculomics’). INSIGHT enables the use of anonymised large-scale data and advanced analytics, including artificial intelligence, to develop new insights in disease detection, diagnosis, treatments and personalised healthcare.

Alastair is a Member of the UK Government’s Regulatory Horizons Council, and is AI Theme Lead for the Centre for Regulatory Science and Innovation (Birmingham, UK).

Activities

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Employment (3)

Health Data Research UK: London, GB

Employment
Source: Self-asserted source
Alastair K Denniston

University of Birmingham: Birmingham, W Midlands, GB

2012-01-01 to present
Employment
Source: Self-asserted source
Alastair K Denniston

University Hospitals Birmingham NHSFT: Birmingham, GB

2012-01-01 to present (Department of Ophthalmology)
Employment
Source: Self-asserted source
Alastair K Denniston

Education and qualifications (7)

General Medical Council: London, London, GB

2011-01-01 to present | Certificate of Completion of Training
Qualification
Source: Self-asserted source
Alastair K Denniston

University of Birmingham: Birmingham, West Midlands, GB

2010-01-01 to present | PhD
Qualification
Source: Self-asserted source
Alastair K Denniston

Royal College of Ophthalmologists: London, London, GB

2010-01-01 to present | FRCOphth (Royal College of Ophthalmologists)
Qualification
Source: Self-asserted source
Alastair K Denniston

Royal College of Ophthalmologists: London, GB

2003-01-01 to present | MRCOphth (Royal College of Ophthalmologists)
Qualification
Source: Self-asserted source
Alastair K Denniston

University of Cambridge: Cambridge, Cambridgeshire, GB

2000-01-01 to present | MA
Qualification
Source: Self-asserted source
Alastair K Denniston

Royal College of Physicians: London, London, GB

2000-01-01 to present | MRCP
Qualification
Source: Self-asserted source
Alastair K Denniston

University of Cambridge: Cambridge, Cambridgeshire, GB

1995-01-01 to present | BA (Hons)
Qualification
Source: Self-asserted source
Alastair K Denniston

Professional activities (13)

Health Data Research UK: London, GB

Membership
Source: Self-asserted source
Alastair K Denniston

Wellcome Trust: London, London, GB

2020-10-01 | State of AI Report
Distinction
Source: Self-asserted source
Alastair K Denniston

Twitter (United States): San Francisco, California, US

2020-02-01 | Two papers nominated (Eric Topol's Top 4 papers for Clinicians wanting to get into AI)
Distinction
Source: Self-asserted source
Alastair K Denniston

Nature: London, London, GB

2019-12-01 | 'Top 5 notable advances of 2019' and #1 for digital health for 'First meta-analysis of AI diagnostics' - Senior author (Nature Medicine)
Distinction
Source: Self-asserted source
Alastair K Denniston

NIHR Central Commissioning Facility: London, GB

2019-09-01 | Highly commended in the Senior Investigator of the Year Award (West Midlands)
Distinction
Source: Self-asserted source
Alastair K Denniston

National Opthalmology Awards: Birmingham, West Midlands, GB

2019-01-01 | Clinical Leadership Award for the Opthalmology Team of the Year (National Opthalmology Awards)
Distinction
Source: Self-asserted source
Alastair K Denniston

University Hospitals Birmingham NHS Foundation Trust: Birmingham, Birmingham, GB

2018-12-01 | 'Best in Care' Award for outstanding care and clinical leadership at Queen Elizabeth Hospitals Birmingham
Distinction
Source: Self-asserted source
Alastair K Denniston

Academy of Medical Sciences: Birmingham, GB

2018-11-01 | Selected for the highly prestigious AMS leadership programme for the life sciences; FLIER, Future Leaders in Innovation, Enterprise and Research
Distinction
Source: Self-asserted source
Alastair K Denniston

West Midlands AHSN: Birmingham, West Midlands, GB

2017-11-01 | Meridian Celebration of Innovation Awards - Awarded 'One to Watch' status in the Advanced Diagnostics, Genomics and Precision Medine Award
Distinction
Source: Self-asserted source
Alastair K Denniston

Health Education England London: London, London, GB

2017-07-01 | Emerging Leader Award (Regional)
Distinction
Source: Self-asserted source
Alastair K Denniston

National Institute for Health Research: London, London, GB

2015-04-01 | Assessing Impact and Directing treatment in patients with Uveitic Macular Oedema (AID UMO) Study (NIHR Academy)
Distinction
Source: Self-asserted source
Alastair K Denniston

University of Birmingham: Birmingham, Birmingham, GB

2011-09-01 | £3,500 College Fellowship Award to support a Clinical Research Fellowship in Uveitis with Professor Andrew Dick at University of Bristol (College of Medical & Dental Sciences)
Distinction
Source: Self-asserted source
Alastair K Denniston

Academy of Medical Sciences: London, London, GB

2011-09-01 | Wellcome AMS Clinical Lecturer Starter Grant of £28,000 awarded for research into predicting outcome for uveitis patients undergoing cataract surgery
Distinction
Source: Self-asserted source
Alastair K Denniston

Funding (18)

Therapies for Long COVID in non-hospitalised individuals: From symptoms, patient-reported outcomes and immunology to targeted therapies (The TLC Study)

2021-03 to 2023-02 | Grant
National Institute for Health Research (London, London, GB)
Source: Self-asserted source
Alastair K Denniston

The ATHENA Study

2020-11 to 2023-10 | Grant
National Institute for Health Research (Southampton, Southampton, GB)
Source: Self-asserted source
Alastair K Denniston

The ASTUTE pragmatic randomized controlled trial

2020-01 to 2023-12 | Grant
National Institute for Health Research (Southampton, Southampton, GB)
Source: Self-asserted source
Alastair K Denniston

The HERMES Study

2019-11 to 2022-10 | Grant
National Institute for Health Research (Southampton, Southampton, GB)
Source: Self-asserted source
Alastair K Denniston

INSIGHT: The Health Data Research Hub for Eye Health

2019-10 to 2022-09 | Award
Innovate UK (London, London, GB)
URL: https://www.hdruk.ac.uk/helping-with-health-data/our-hubs-across-the-uk/insight/
Source: Self-asserted source
Alastair K Denniston

PIONEER: The Health Data Research Hub for Acute Care

2019-10 to 2021-04 | Award
Innovate UK (London, London, GB)
URL: https://www.hdruk.ac.uk/helping-with-health-data/our-hubs-across-the-uk/pioneer/
Source: Self-asserted source
Alastair K Denniston

Quantitative Imaging and Artificial Intelligence in Birdshot Chorioretinopathy

2019-09 to 2022-09 | Grant
Fight for Sight UK (London, London, GB)
URL: https://www.fightforsight.org.uk/our-research/
Source: Self-asserted source
Alastair K Denniston

Quantitative Imaging using Swept Source Anterior Segment OCT

2018-11 to 2020-08 | Grant
Heidelberg Engineering (Franklin, MA 02038, Franklin, MA 02038, DE)
Source: Self-asserted source
Alastair K Denniston

Delivering 'drop-based' immunotherapeutic therapy to the choroid and retina

2018-08 to 2021-08 | Grant
Fight for Sight UK (London, London, GB)
URL: https://www.fightforsight.org.uk/
Source: Self-asserted source
Alastair K Denniston

Tackling Blindness through Quantitative Imaging

2018-08 to 2020-08 | Grant
HB Allen Charitable Trust (London, London, GB)
Source: Self-asserted source
Alastair K Denniston

Measuring Uveitis Activity Using Spectral Domain Optical Coherence Tomography Research Enrichment

2018-04 to 2020-11 | Grant
Wellcome Trust (London, London, GB)
Source: Self-asserted source
Alastair K Denniston

Measuring Uveitis Activity using Spectral Domain Optical Coherence Tomography

2017-11-01 to 2020-10-31 | Grant
Wellcome Trust (London, GB)
URL: https://app.dimensions.ai/details/grant/grant.7159869
GRANT_NUMBER:

200141/Z/15/Z
Source: Self-asserted source
Alastair K Denniston via DimensionsWizard

Treatment According to Response in Giant cEll arTeritis

2017-11 to 2020-11 | Grant
Medical Research Council (London, London, GB)
URL: https://mrc.ukri.org/
Source: Self-asserted source
Alastair K Denniston

Measuring Uveitis Activity Using Spectral Domain Optical Coherence Tomography

2016-04 to 2019-04 | Grant
Wellcome Trust (London, London, GB)
Source: Self-asserted source
Alastair K Denniston

Assessing Impact and Directing treatment in patients eith Uveitic Macular Oedema

2015-08 to 2020-08 | Grant
National Institute for Health Research (Southampton, Southampton, GB)
Source: Self-asserted source
Alastair K Denniston

Colour Contrast Sensitivity for the Detection of Pre-Symptomatic Stage of Neovascular Age-Related Macular Degeneration

2014-02 to 2017-02 | Grant
Dunhill Medical Trust (London, London, GB)
URL: https://dunhillmedical.org.uk/
Source: Self-asserted source
Alastair K Denniston

Equipment grant for Multicolour Spectralis HRA-OCT Retinal Imaging and PASCAL Laser

2012-10 to 2013-10 | Grant
QEHB Charities (Birmingham, Birmingham, GB)
Source: Self-asserted source
Alastair K Denniston

Predicting risk in patients with uveitis undergoing cataract surgery.

2011-09-26 to present | Grant
Academy of Medical Sciences (London, GB)
URL: https://app.dimensions.ai/details/grant/grant.6909394
GRANT_NUMBER:

None-SGL005\1007
Source: Self-asserted source
Alastair K Denniston via DimensionsWizard

Peer review (1 review for 1 publication/grant)

Review activity for Nature biomedical engineering. (1)
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