Personal information

Biography

Professor of Ophthalmology, Centre for Ophthalmology and Visual Science since 2009.
David is internationally recognised as a genetic ophthalmologist with over 350 publications. From 2005-09 he was Pfizer Australia Senior Research Fellow and in 2010 an Alcon Research Institute Awardee. Before moving to Western Australia in 2009, he was Associate Professor at University of Melbourne’s Department of Ophthalmology and Clinical Professor at the University of Tasmania. In 1993 he initiated the Glaucoma Inheritance Study in Tasmania, creating one of the largest glaucoma biobanks in the world. He leads the Twins Eye Studies in Tasmania and WA and several genetic and epidemiological eye health studies in WA.

Activities

Employment (10)

The University of Western Australia: Perth, AU

Employment
Source: check_circle
University of Western Australia

The University of Western Australia: Crawley, WA, AU

2009-03-05 to present | Professor of Ophthalmology (Centre for Ophthalmology & Visual Science)
Employment
Source: Self-asserted source
David Mackey AO

Lions Eye Institute: Nedlands, WA, AU

2009-03-05 to 2019-03-04 | Managing Director
Employment
Source: Self-asserted source
David Mackey AO

University of Western Australia: WA, WA, AU

2016-01-01 to 2017-02-01 | Associate Dean (Research) (Faculty of Medicine Dentistry & Health Sciences)
Employment
Source: Self-asserted source
David Mackey AO

University of Melbourne: Melbourne, VIC, AU

1997 to 2009-02 | Associate Professor (Department of Opthalmology)
Employment
Source: Self-asserted source
David Mackey AO

University of Tasmania: Hobart, TAS, AU

2005 to 2009 | Clinical Professor, Pfizer Australia Senior Research Fellow
Employment
Source: Self-asserted source
David Mackey AO

University of Melbourne: Melbourne, VIC, AU

1994 to 1996 | Senior Lecturer (Department of Paediatrics)
Employment
Source: Self-asserted source
David Mackey AO

Moorfields Eye Hospital: London, London, GB

1993 to 1993 | Wellcome Research Fellow, Clinical Fellow in Hereditary eye diseases
Employment
Source: Self-asserted source
David Mackey AO

Johns Hopkins Wilmer Eye Institute: Baltimore, MD, US

1991 to 1993 | Clinical Fellow in Ophthalmology
Employment
Source: Self-asserted source
David Mackey AO

Royal Children's Hospital: Melbourne, VIC, AU

1990 to 1991 | Clinical Research Fellow in Ophthalmology
Employment
Source: Self-asserted source
David Mackey AO

Education and qualifications (6)

The University of Western Australia: Perth, AU

Education
Source: check_circle
University of Western Australia

Royal Australian and New Zealand College of Ophthalmologists: Surry Hills, NSW, AU

1991 to present | FRANCZO
Education
Source: Self-asserted source
David Mackey AO

Royal Australasian College of Surgeons: Melbourne, VIC, AU

1991 to present | FRACS
Education
Source: Self-asserted source
David Mackey AO

University of Melbourne: Melbourne, VIC, AU

1993-03 | M.D.
Education
Source: Self-asserted source
David Mackey AO

University of Tasmania: Hobart, TAS, AU

1983-12 | M.B.B.S.
Education
Source: Self-asserted source
David Mackey AO

University of Tasmania: Hobart, TAS, AU

1980-12 | B.Med. Sci.
Education
Source: Self-asserted source
David Mackey AO

Professional activities (11)

Asia-Pacific Academy of Ophthalmology: Hong Kong, CN

Regional Secretary [Australia & New Zealand] and Chair of the Membership Committee, 2016-current): Vice-President (elected Feb 2023)
Membership
Source: Self-asserted source
David Mackey AO

Academia Ophthalmologica Internationalis: San Francisco, US

2024 to present | Member
Membership
Source: Self-asserted source
David Mackey AO

Academy of Asia-Pacific Professors of Ophthalmology : Hong Kong, HK

2017 to present | Fellow
Membership
Source: Self-asserted source
David Mackey AO

Australian Academy of Health and Medical Sciences: Brisbane, Queensland, AU

2014 to present | Fellow
Membership
Source: Self-asserted source
David Mackey AO

Glaucoma Research Society: Baltimore, US

2010 to present | Member
Membership
Source: Self-asserted source
David Mackey AO

International Society for Genetic Eye Disease and Retinoblastoma: Cleveland, US

2009 to present | Member
Membership
Source: Self-asserted source
David Mackey AO

Royal Australian and New Zealand College of Ophthalmologists: Surry Hills, NSW, AU

1991 to present | Fellow
Membership
Source: Self-asserted source
David Mackey AO

Winston Churchill Memorial Trust: ACT, ACT, AU

2015 | Kevin Bell Winston Churchill Fellowship Trust Award 2015
Distinction
Source: Self-asserted source
David Mackey AO

Harvard Club of Australia: Sydney, New South Wales, AU

2014 | Nonprofit Fellowship Award: Strategic Perspectives in Nonprofit Management
Distinction
Source: Self-asserted source
David Mackey AO

Alcon Research Institute: Fort Worth, TX, US

2010 | Alcon Research Institute 2010 Awardee
Distinction
Source: Self-asserted source
David Mackey AO

University of Tasmania: TAS, TAS, AU

2009 | University Foundation Graduate Award
Distinction
Source: Self-asserted source
David Mackey AO

Funding (43)

Preventing myopia and glaucoma in children at high genetic risk, leveraging the Western Australian Origins Project and the Raine Study

2024-01 to 2026-12 | Grant
Stan Perron Charitable Foundation (WA, WA, AU)
Source: Self-asserted source
David Mackey AO

Profiling the choroidal genetics to determine its role in myopia and myopic macular degeneration

2024-01 to 2024-12 | Grant
Ophthalmic Research Institute of Australia (Sydney, AU)
Source: Self-asserted source
David Mackey AO

Genetic risk and trajectories of aging influencing glaucoma in the Busselton Baby Boomer Study.

2024 to 2027 | Grant
WA Health (East Perth, AU)
Source: Self-asserted source
David Mackey AO

What is the normal range of intraocular pressure in children and young adults, and does it predict later glaucoma?

2023-11 to 2025-06 | Grant
Glaucoma Australia (NSW, NSW, AU)
GRANT_NUMBER:

Quinlivan Research Grant

Source: Self-asserted source
David Mackey AO

Understanding the genetic, environmental, hormonal and other factors that could trigger vision loss from Leber Hereditary Optic Neuropathy

2023-11 to 2024-04 | Grant
Mito Foundation (NSW, NSW, AU)
GRANT_NUMBER:

G192

Source: Self-asserted source
David Mackey AO

Introducing Mitochondrial Donation into Australia: The mitoHOPE (Healthy Outcomes Pilot and Evaluation) Program

2023-06 to 2028-05 | Grant
National Health and Medical Research Council (Canberra, Australian Capital Territory, AU)
GRANT_NUMBER:

MRFF 2023189

Source: Self-asserted source
David Mackey AO

Ensuring genetics based prediction of glaucoma can benefit all Australians

2022-06 to 2024-06 | Grant
National Health and Medical Research Council (ACT, ACT, AU)
GRANT_NUMBER:

MRFF 2017350

Source: Self-asserted source
David Mackey AO

Applying machine learning to efficiently analyse fundus autofluorescence images in preparation for gene therapy

2021 to 2021 | Grant
Ophthalmic Research Institute of Australia (NSW, NSW, AU)
Source: Self-asserted source
David Mackey AO

Translating genetic determinants of glaucoma into better diagnosis and treatment

2019-01 to 2023-12 | Grant
National Health and Medical Research Council (ACT, ACT, AU)
GRANT_NUMBER:

1150144

Source: Self-asserted source
David Mackey AO

Understanding, predicting, preventing and treating the highly heritable, common eye diseases glaucoma and myopia to reduce blindness and visual impairment

2019-01 to 2023-12 | Grant
National Health and Medical Research Council (ACT, ACT, AU)
GRANT_NUMBER:

1154518

Source: Self-asserted source
David Mackey AO
grade
Preferred source (of 2)‎

Establishing Risk of Vision Loss in Leber Hereditary Optic Neuropathy Families

2018 to 2018 | Grant
The Ophthalmic Research Institute of Australia (NSW, NSW, AU)
Source: Self-asserted source
David Mackey AO

Young adult myopia: genetic and environmental associations

2017-01 to 2020-12 | Grant
National Health and Medical Research Council (Canberra, ACT, AU)
GRANT_NUMBER:

1121979

Source: Self-asserted source
David Mackey AO

Targeting at risk relatives of glaucoma patients for early diagnosis and treatment (TARRGET)

2016-12 to 2019-11 | Grant
National Health and Medical Research Council (Canberra, ACT, AU)
GRANT_NUMBER:

1132454

Source: Self-asserted source
David Mackey AO

From discovery to therapy in genetic eye diseases

2016-11 to 2021-10 | Grant
National Health and Medical Research Council (Canberra, ACT, AU)
GRANT_NUMBER:

1116360

Source: Self-asserted source
David Mackey AO

Preparing Australia for the Genomics Revolution

2016 to 2020 | Grant
National Health and Medical Research Council (Canberra, ACT, AU)
GRANT_NUMBER:

1113531

Source: Self-asserted source
David Mackey AO

Pathways to treatment in blinding genetic retinal eye diseases

2016 to 2018 | Grant
National Health and Medical Research Council (Canberra, ACT, AU)
GRANT_NUMBER:

1099165

Source: Self-asserted source
David Mackey AO

WA Atom pilot study: Atropine treatment of myopia

2016 to 2017 | Grant
Telethon - Perth Children's Hospital Research Fund (Perth, Western Australia, AU)
Source: Self-asserted source
David Mackey AO

Mass Cytometry: A breakthrough in multidimensional systems biology

2016 to 2016 | Grant
Australian Research Council (Canberra, ACT, AU)
GRANT_NUMBER:

LEI150100066

Source: Self-asserted source
David Mackey AO

Modelling LHON using human induced pluripotent stem cells

2015 to 2017 | Grant
National Health and Medical Research Council (Canberra, ACT, AU)
GRANT_NUMBER:

1084256

Source: Self-asserted source
David Mackey AO

Optic Nerve Structure and Gene-Environment Association

2014-07-01 to 2016-06-30 | Grant
BrightFocus Foundation (Clarksburg, US)
GRANT_NUMBER:

G2014032

Source: check_circle
ProposalCentral

Centres of Research Excellence in Twin Research

2014-03 to 2018-03 | Grant
National Health and Medical Research Council (ACT, ACT, AU)
GRANT_NUMBER:

1079102

Source: Self-asserted source
David Mackey AO

Energy therapy to preserve vision in young men at risk of blindness

2014-01-01 to 2016-12-31 | Grant
National Health and Medical Research Council (Canberra, AU)
GRANT_NUMBER: 1061472
GRANT_NUMBER: 1061472
Source: Self-asserted source
David Mackey AO via DimensionsWizard

Identifying glaucoma risk variants in the Norfolk island genetic isolate

2014-01-01 to 2016-12-31 | Grant
National Health and Medical Research Council (Canberra, AU)
GRANT_NUMBER: 1058806
GRANT_NUMBER: 1058806
Source: Self-asserted source
David Mackey AO via DimensionsWizard

Finding glaucoma genes by sequencing large families known to carry susceptibility variants

2013-01-01 to 2015-12-31 | Grant
National Health and Medical Research Council (Canberra, AU)
GRANT_NUMBER: 1044996
GRANT_NUMBER: 1044996
Source: Self-asserted source
David Mackey AO via DimensionsWizard

The long-term consequences of IVF treatment for the offspring - a prospective cohort study using the Raine Cohort for comparison

2013 to 2017 | Grant
National Health and Medical Research Council (ACT, ACT, AU)
GRANT_NUMBER:

1042269

Source: Self-asserted source
David Mackey AO

Towards translation of glaucoma blindness genes into clinical practice: predicting risk of Glaucoma: Relevant SNPs with Strong Association (PROGRESSA) Study

2013 to 2017 | Grant
National Health and Medical Research Council (Canberra, ACT, AU)
GRANT_NUMBER:

1048037

Source: Self-asserted source
David Mackey AO

Translation of genetic eye research

2012-01-01 to 2016-12-31 | Grant
National Health and Medical Research Council (Canberra, AU)
GRANT_NUMBER: 1023911
GRANT_NUMBER: 1023911
Source: Self-asserted source
David Mackey AO via DimensionsWizard

Genes for juvenile-onset myopia

2012-01-01 to 2014-12-31 | Grant
National Health and Medical Research Council (Canberra, AU)
GRANT_NUMBER: 1021105
GRANT_NUMBER: 1021105
Source: Self-asserted source
David Mackey AO via DimensionsWizard

Genetic etiologies of congenital esotropia

2012-01-01 to 2014-12-31 | Grant
National Health and Medical Research Council (Canberra, AU)
GRANT_NUMBER: 1031920
GRANT_NUMBER: 1031920
Source: Self-asserted source
David Mackey AO via DimensionsWizard

Myopia and colour vision

2012-01-01 to 2013-12-31 | Grant
National Health and Medical Research Council (Canberra, AU)
GRANT_NUMBER: 1030148
GRANT_NUMBER: 1030148
Source: Self-asserted source
David Mackey AO via DimensionsWizard

The role of EPHA2 signalling and environmental modifiers in cataract

2011 to 2013 | Grant
National Health and Medical Research Council (Canberra, ACT, AU)
GRANT_NUMBER:

1009955

Source: Self-asserted source
David Mackey AO
grade
Preferred source (of 2)‎

Energy supply and nerve protection in inherited eye diseases

2010-01-01 to 2012-12-31 | Grant
National Health and Medical Research Council (Canberra, AU)
GRANT_NUMBER: 590200
GRANT_NUMBER: 590200
Source: Self-asserted source
David Mackey AO via DimensionsWizard

The role of low sun exposure in the onset of type 1 diabetes mellitus.

2010 to 2012 | Grant
National Health Medical Research Centre (ACT, ACT, AU)
GRANT_NUMBER:

546425

Source: Self-asserted source
David Mackey AO

A genome-wide association scan for glaucoma

2009-01-01 to 2011-12-31 | Grant
National Health and Medical Research Council (Canberra, AU)
GRANT_NUMBER: 535074
GRANT_NUMBER: 535074
Source: Self-asserted source
David Mackey AO via DimensionsWizard

Molecular basis of pseudoexfoliation syndrome

2009-01-01 to 2011-12-31 | Grant
National Health and Medical Research Council (Canberra, AU)
GRANT_NUMBER: 535044
GRANT_NUMBER: 535044
Source: Self-asserted source
David Mackey AO via DimensionsWizard

Investigation of central corneal thickness in relation to glaucoma

2009-01-01 to 2010-12-31 | Grant
National Health and Medical Research Council (Canberra, AU)
GRANT_NUMBER: 535077
GRANT_NUMBER: 535077
Source: Self-asserted source
David Mackey AO via DimensionsWizard

Genetic studies of cataracts

2007-01-01 to 2009-12-31 | Grant
National Health and Medical Research Council (Canberra, AU)
GRANT_NUMBER: 426753
GRANT_NUMBER: 426753
Source: Self-asserted source
David Mackey AO via DimensionsWizard

Ophthalmic Examination of Dizygotic Twins in Queensland

2005-04-01 to 2007-03-31 | Grant
BrightFocus Foundation (Clarksburg, US)
GRANT_NUMBER:

G2005002

Source: check_circle
ProposalCentral

TWIN EYE STUDY OF GLAUCOMA

2005-01-01 to 2007-12-31 | Grant
National Health and Medical Research Council (Canberra, AU)
GRANT_NUMBER: 350415
GRANT_NUMBER: 350415
Source: Self-asserted source
David Mackey AO via DimensionsWizard

Genetic studies of congenital cataract

2004-01-01 to 2006-12-31 | Grant
National Health and Medical Research Council (Canberra, AU)
GRANT_NUMBER: 275566
GRANT_NUMBER: 275566
Source: Self-asserted source
David Mackey AO via DimensionsWizard

Genetics of Optic Neuropathies including Glaucoma

2003-01-01 to 2005-12-31 | Grant
National Health and Medical Research Council (Canberra, AU)
GRANT_NUMBER: 229960
GRANT_NUMBER: 229960
Source: Self-asserted source
David Mackey AO via DimensionsWizard

The genetics of glaucoma

2000 to 2002 | Grant
National Health and Medical Research Council (ACT, ACT, AU)
GRANT_NUMBER:

128202

Source: Self-asserted source
David Mackey AO

High penetrance deleterious mutations in blinding glaucoma

Grant
NHMRC (CANBERRA, AU)
GRANT_NUMBER:

1107098

GRANT_NUMBER:

1107098

Source: Self-asserted source
David Mackey AO
grade
Preferred source (of 2)‎

Peer review (10 reviews for 6 publications/grants)

Review activity for Cell. (2)
Review activity for Eye (3)
Review activity for Journal of AAPOS (2)
Review activity for Nature communications (1)
Review activity for Ophthalmology and therapy. (1)
Review activity for Orphanet journal of rare diseases. (1)