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ResearcherID: A-7186-2010

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Employment (1)

University of Glasgow: Glasgow, Glasgow, GB

2009-08-01 to present | Professor (Institute of Infection, Immunity and Inflammation)
Employment
Source: Self-asserted source
James Brewer

Education and qualifications (2)

University of Strathclyde: Glasgow, Glasgow, GB

1989-10-01 to 1992-09-30 | Ph.D. (Immunology)
Education
Source: Self-asserted source
James Brewer

University of Strathclyde: Glasgow, Glasgow, GB

1985-10-01 to 1989-06-01 | B.Sc (Immunology)
Education
Source: Self-asserted source
James Brewer

Works (50 of 127)

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Page 1 of 3

The effect of abatacept on T-cell activation is not long-lived in vivo

Discovery Immunology
2024-01-01 | Journal article
DOI: 10.1093/discim/kyad029
Contributors: Larissa C da Rosa; Hannah E Scales; Robert A Benson; James M Brewer; Iain B McInnes; Paul Garside
Source: check_circle
Crossref

Spermidine suppresses DC activation via eIF5A hypusination and metabolic adaptation

2023-12-08 | Preprint
DOI: 10.1101/2023.12.07.570665
Contributors: Gavin R Meehan; Utku Gunes; Hannah E Scales; George Finney; Ross Deehan; Sofia Sintoris; Aegli Athanasiadou; James M Brewer
Source: check_circle
Crossref

Review: Unravelling the Role of DNA Sensing in Alum Adjuvant Activity

Discovery Immunology
2023-01-01 | Journal article
DOI: 10.1093/discim/kyac012
Contributors: Zara Gatt; Utku Gunes; Arianna Raponi; Larissa Camargo da Rosa; James M Brewer
Source: check_circle
Crossref

A discovery pipeline for identification and in vivo validation of drugs that alter T cell/ dendritic cell interaction

2022-04-12 | Preprint
DOI: 10.1101/2022.04.11.487526
Contributors: Hannah E. Scales; Chantal Keijzer; Emma Evertsson; Paul Garside; Stephen Delaney; James M. Brewer
Source: check_circle
Crossref

Dissecting the molecular control of immune cell accumulation in the inflamed joint

JCI Insight
2022-04-08 | Journal article
DOI: 10.1172/jci.insight.151281
Contributors: Catriona T. Prendergast; Robert A. Benson; Hannah E. Scales; Caio Santos Bonilha; John J. Cole; Iain McInnes; James M. Brewer; Paul Garside
Source: check_circle
Crossref

Orally administered antigen can reduce or exacerbate pathology in an animal model of inflammatory arthritis dependent upon the timing of administration

2022-01-08 | Preprint
DOI: 10.1101/2022.01.07.475399
Contributors: Gavin R Meehan; Iain B McInnes; James M Brewer; Paul Garside
Source: check_circle
Crossref

Revealing stromal and lymphoid sources of Col3a1-expression during inflammation using a novel reporter mouse

Discovery Immunology
2022-01-01 | Journal article
DOI: 10.1093/discim/kyac008
Contributors: Larissa C da Rosa; Hannah E Scales; Sangeet Makhija; Katie Sutherland; Robert A Benson; James M Brewer; Paul Garside
Source: check_circle
Crossref

Junctional adhesion molecule-A on dendritic cells regulates Th1 differentiation

Immunology Letters
2021-07 | Journal article
DOI: 10.1016/j.imlet.2021.05.001
Contributors: Caio S. Bonilha; Robert A. Benson; Hannah E. Scales; James M. Brewer; Paul Garside
Source: check_circle
Crossref

Developing a xenograft model of human vasculature in the mouse ear pinna

Scientific Reports
2020-02-06 | Journal article
DOI: 10.1038/s41598-020-58650-y
Contributors: Gavin R. Meehan; Hannah E. Scales; Rowland Osii; Mariana De Niz; Jennifer C. Lawton; Matthias Marti; Paul Garside; Alister Craig; James M. Brewer
Source: check_circle
Crossref

Developing a xenograft model of human vasculature in the mouse ear pinna

2019-10-02 | Other
DOI: 10.1101/789537
Contributors: Gavin R. Meehan; Hannah E. Scales; Rowland Osii; Mariana De Niz; Jennifer C. Lawton; Matthias Marti; Paul Garside; Alister Craig; James M. Brewer
Source: check_circle
Crossref

Spatiotemporal Modeling of the Key Migratory Events During the Initiation of Adaptive Immunity.

Frontiers in immunology
2019-04-05 | Journal article
DOI: 10.3389/fimmu.2019.00598
PMID: 31024523
PMC: PMC6460458
Source: Self-asserted source
James Brewer

Effects of host-derived chemokines on the motility and viability of Trypanosoma brucei.

Parasite immunology
2018-12-27 | Journal article
DOI: 10.1111/pim.12609
PMID: 30525202
Source: Self-asserted source
James Brewer

In vivo multiplex molecular imaging of vascular inflammation using surface-enhanced Raman spectroscopy.

Theranostics
2018-11-29 | Journal article
DOI: 10.7150/thno.28665
PMID: 30613292
PMC: PMC6299693
Source: Self-asserted source
James Brewer

A Novel Cellular Pathway of Antigen Presentation and CD4 T Cell Activation in vivo.

Frontiers in immunology
2018-11-22 | Journal article
DOI: 10.3389/fimmu.2018.02684
PMID: 30524434
PMC: PMC6262026
Source: Self-asserted source
James Brewer

Non-Invasive Multiphoton Imaging of Islets Transplanted Into the Pinna of the NOD Mouse Ear Reveals the Immediate Effect of Anti-CD3 Treatment in Autoimmune Diabetes.

Frontiers in immunology
2018-05-18 | Journal article
DOI: 10.3389/fimmu.2018.01006
PMID: 29867981
PMC: PMC5968092
Source: Self-asserted source
James Brewer

A cryptic cycle in haematopoietic niches promotes initiation of malaria transmission and evasion of chemotherapy

Nature Communications
2018-04-27 | Journal article
DOI: 10.1038/s41467-018-04108-9
Contributors: Rebecca S. Lee; Andrew P. Waters; James M. Brewer
Source: check_circle
Crossref

Visualising the interaction of CD4 T cells and DCs in the evolution of inflammatory arthritis.

Annals of the rheumatic diseases
2018-01-22 | Journal article
DOI: 10.1136/annrheumdis-2017-212279
PMID: 29358281
Source: Self-asserted source
James Brewer

Model answers: Rational application of murine models in arthritis research.

European journal of immunology
2017-12-14 | Journal article
DOI: 10.1002/eji.201746938
PMID: 29193037
PMC: PMC5814907
Source: Self-asserted source
James Brewer

SipA Activation of Caspase-3 Is a Decisive Mediator of Host Cell Survival at Early Stages of Salmonella enterica Serovar Typhimurium Infection.

Infection and immunity
2017-08-18 | Journal article
DOI: 10.1128/IAI.00393-17
PMID: 28630067
PMC: PMC5563584
Source: Self-asserted source
James Brewer

MicroRNA-34a dependent regulation of AXL controls the activation of dendritic cells in inflammatory arthritis.

Nature communications
2017-06-22 | Journal article
DOI: 10.1038/ncomms15877
PMID: 28639625
PMC: PMC5489689
Source: Self-asserted source
James Brewer

Multispectral oximetry of murine tendon microvasculature with inflammation.

Biomedical optics express
2017-05-08 | Journal article
DOI: 10.1364/BOE.8.002896
PMID: 28663914
PMC: PMC5480437
Source: Self-asserted source
James Brewer

Neutrophil swarming and extracellular trap formation play a significant role in Alum adjuvant activity.

NPJ vaccines
2017-01-23 | Journal article
DOI: 10.1038/s41541-016-0001-5
PMID: 29263862
PMC: PMC5604741
Source: Self-asserted source
James Brewer

Abatacept Inhibition of T Cell Priming in Mice by Induction of a Unique Transcriptional Profile That Reduces Their Ability to Activate Antigen-Presenting Cells.

2016-03 | Journal article
DOI: 10.1002/art.39470
PMID: 26473409
Contributors: Patakas A; Ji RR; Weir W; Connolly SE; Benson RA; Nadler SG; Brewer JM; McInnes IB; Garside P
Source: Self-asserted source
James Brewer via Europe PubMed Central

Assessment of murine collagen-induced arthritis by longitudinal non-invasive duplexed molecular optical imaging.

2016-03 | Journal article
DOI: 10.1093/rheumatology/kev361
PMID: 26475798
Contributors: Scales HE; Ierna M; Smith KM; Ross K; Meiklejohn GR; Patterson-Kane JC; McInnes IB; Brewer JM; Garside P; Maffia P
Source: Self-asserted source
James Brewer via Europe PubMed Central

Perivascular Arrest of CD8+ T Cells Is a Signature of Experimental Cerebral Malaria.

2015 | Journal article
DOI: 10.1371/journal.ppat.1005210
PMID: 26562533
PMC: PMC4643016
Contributors: Shaw TN; Stewart-Hutchinson PJ; Strangward P; Dandamudi DB; Coles JA; Villegas-Mendez A; Gallego-Delgado J; van Rooijen N; Zindy E; Rodriguez A et al.
Source: Self-asserted source
James Brewer via Europe PubMed Central

Antigen presentation kinetics control T cell/dendritic cell interactions and follicular helper T cell generation in vivo

eLife
2015-08-10 | Journal article
DOI: 10.7554/eLife.06994
Contributors: Robert A Benson; Megan KL MacLeod; Benjamin G Hale; Agapitos Patakas; Paul Garside; James M Brewer
Source: check_circle
Crossref

Artery Tertiary Lymphoid Organs Control Aorta Immunity and Protect against Atherosclerosis via Vascular Smooth Muscle Cell Lymphotoxin β Receptors.

2015-06 | Journal article
DOI: 10.1016/j.immuni.2015.05.015
PMID: 26084025
PMC: PMC4678289
Contributors: Hu D; Mohanta SK; Yin C; Peng L; Ma Z; Srikakulapu P; Grassia G; MacRitchie N; Dever G; Gordon P et al.
Source: Self-asserted source
James Brewer via Europe PubMed Central

Cellular imaging in rheumatic diseases.

2015-06 | Journal article
DOI: 10.1038/nrrheum.2015.34
PMID: 25800215
Contributors: Benson RA; McInnes IB; Brewer JM; Garside P
Source: Self-asserted source
James Brewer via Europe PubMed Central

Intravital imaging of a massive lymphocyte response in the cortical dura of mice after peripheral infection by trypanosomes.

2015-04 | Journal article
DOI: 10.1371/journal.pntd.0003714
PMID: 25881126
PMC: PMC4400075
Contributors: Coles JA; Myburgh E; Ritchie R; Hamilton A; Rodgers J; Mottram JC; Barrett MP; Brewer JM
Source: Self-asserted source
James Brewer via Europe PubMed Central

Mechanisms of autoimmunity in human diseases: a critical review of current dogma

Current opinion in rheumatology
2014 | Journal article
DOI: 10.1097/BOR.0000000000000037
WOSUID:

WOS:000332829900020
Contributors: Benson, Robert a; Brewer, James M.; Platt, Andrew M.
Source: Self-asserted source
James Brewer via ResearcherID

MHCII-Mediated Dialog between Group 2 Innate Lymphoid Cells and CD4+ T Cells Potentiates Type 2 Immunity and Promotes Parasitic Helminth Expulsion

Immunity
2014 | Journal article
DOI: 10.1016/j.immuni.2014.06.016
WOSUID:

WOS:000341455300015
Contributors: Oliphant, Christopher J; Hwang, You Yi; Walker, Jennifer A; Salimi, Maryam; Wong, See Heng; Brewer, James M; Englezakis, Alexandros; Barlow, Jillian L; Hams, Emily; Scanlon, Seth T et al.
Source: Self-asserted source
James Brewer via ResearcherID

Murine aortic smooth muscle cells acquire, though fail to present exogenous protein antigens on major histocompatibility complex class II molecules.

2014 | Journal article
DOI: 10.1155/2014/949845
PMID: 25136640
PMC: PMC4127268
Contributors: Maddaluno M; MacRitchie N; Grassia G; Ialenti A; Butcher JP; Garside P; Brewer JM; Maffia P
Source: Self-asserted source
James Brewer via Europe PubMed Central

The active metabolite of spleen tyrosine kinase inhibitor fostamatinib abrogates the CD4+ T cell-priming capacity of dendritic cells

Rheumatology (Oxford, England)
2014 | Journal article
DOI: 10.1093/rheumatology/keu273
WOSUID:

WOS:000350211000028
Contributors: Platt, Andrew M.; Benson, Robert a; McQueenie, Ross; Butcher, John P.; Braddock, Martin; Brewer, James M.; McInnes, Iain B.; Garside, Paul
Source: Self-asserted source
James Brewer via ResearcherID

Using lymph node transplantation as an approach to image cellular interactions between the skin and draining lymph nodes during parasitic infections.

2014-02 | Journal article
DOI: 10.1016/j.parint.2013.07.010
PMID: 23892176
PMC: PMC3863950
Contributors: Lawton JC; Benson RA; Garside P; Brewer JM
Source: Self-asserted source
James Brewer via Europe PubMed Central

In vivo imaging of trypanosome-brain interactions and development of a rapid screening test for drugs against CNS stage trypanosomiasis

PLoS neglected tropical diseases
2013 | Journal article
DOI: 10.1371/journal.pntd.0002384
Contributors: Myburgh, Elmarie; Coles, Jonathan a; Ritchie, Ryan; Kennedy, Peter G. E.; McLatchie, Alex P.; Rodgers, Jean; Taylor, Martin C.; Barrett, Michael P.; Brewer, James M.; Mottram, Jeremy C.
Source: Self-asserted source
James Brewer via ResearcherID

Plasmacytoid dendritic cells : Biomarkers or potential therapeutic targets in atherosclerosis ?

Pharmacology & Therapeutics
2013 | Journal article
DOI: 10.1016/j.pharmthera.2012.10.001
WOSUID:

WOS:000314560700003
Contributors: Grassia, Gianluca; Macritchie, Neil; Platt, Andrew M.; Brewer, James M.; Garside, Paul; Maffia, Pasquale
Source: Self-asserted source
James Brewer via ResearcherID

Analysis of intracellular enzyme activity by surface enhanced Raman scattering.

2013-11 | Journal article
DOI: 10.1039/c3an00729d
PMID: 24003438
Contributors: Stevenson R; McAughtrie S; Senior L; Stokes RJ; McGachy H; Tetley L; Nativo P; Brewer JM; Alexander J; Faulds K et al.
Source: Self-asserted source
James Brewer via Europe PubMed Central

A novel method to allow non-invasive, longitudinal imaging of the murine immune system in vivo

Blood
2012 | Journal article
DOI: 10.1182/blood-2011-09-378356
WOSUID:

WOS:000301941700022
Contributors: Gibson, Vivienne B.; Benson, Robert a; Bryson, Karen J.; McInnes, Iain B.; Rush, Catherine M.; Grassia, Gianluca; Maffia, Pasquale; Jenkinson, Eric J.; White, Andrea J.; Anderson, Graham et al.
Source: Self-asserted source
James Brewer via ResearcherID

Acute inflammatory response to cobalt chromium orthopaedic wear debris in a rodent air-pouch model

Journal of the Royal Society Interface
2012 | Journal article
DOI: 10.1098/rsif.2012.0006
WOSUID:

WOS:000306750500008
Contributors: Akbar, Moeed; Fraser, Alasdair R.; Graham, Gerard J.; Brewer, James M.; Grant, M. Helen
Source: Self-asserted source
James Brewer via ResearcherID

Alum increases antigen uptake, reduces antigen degradation and sustains antigen presentation by DCs in vitro

Immunology Letters
2012 | Journal article
DOI: 10.1016/j.imlet.2012.06.002
WOSUID:

WOS:000309310600008
Contributors: Ghimire, Tirth R.; Benson, Robert A.; Garside, Paul; Brewer, James M.
Source: Self-asserted source
James Brewer via ResearcherID

Antigen depot is not required for alum adjuvanticity

Faseb Journal
2012 | Journal article
DOI: 10.1096/fj.11-184556
WOSUID:

WOS:000300949300029
Contributors: Hutchison, Sharon; Benson, Robert A.; Gibson, Vivienne B.; Pollock, Abigail H.; Garside, Paul; Brewer, James M.
Source: Self-asserted source
James Brewer via ResearcherID

Detection of inflammation in vivo by surface-enhanced Raman scattering provides higher sensitivity than conventional fluorescence imaging

Analytical chemistry
2012 | Journal article
DOI: 10.1021/ac3006445
WOSUID:

WOS:000306441200022
Contributors: McQueenie, Ross; Stevenson, Ross; Benson, Robert; MacRitchie, Neil; McInnes, Iain; Maffia, Pasquale; Faulds, Karen; Graham, Duncan; Brewer, James; Garside, Paul
Source: Self-asserted source
James Brewer via ResearcherID

Plasmacytoid Dendritic Cells Play a Key Role in Promoting Atherosclerosis in Apolipoprotein E-Deficient Mice

Arteriosclerosis Thrombosis and Vascular Biology
2012 | Journal article
DOI: 10.1161/ATVBAHA.112.251314
WOSUID:

WOS:000310058900009
Contributors: MacRitchie, Neil; Grassia, Gianluca; Sabir, Suleman R.; Maddaluno, Marcella; Welsh, Paul; Sattar, Naveed; Ialenti, Armando; Kurowska-Stolarska, Mariola; McInnes, Iain B.; Brewer, James M. et al.
Source: Self-asserted source
James Brewer via ResearcherID

Th17 Effector Cells Support B Cell Responses Outside of Germinal Centres

Plos One
2012 | Journal article
DOI: 10.1371/journal.pone.0049715
WOSUID:

WOS:000311885300061
Contributors: Patakas, Agapitos; Benson, Robert A.; Withers, David R.; Conigliaro, Paola; McInnes, Iain B.; Brewer, James M.; Garside, Paul
Source: Self-asserted source
James Brewer via ResearcherID

Arthritis in space and time - To boldly go!

Febs Letters
2011 | Journal article
DOI: 10.1016/j.febslet.2011.04.069
WOSUID:

WOS:000297318000007
Contributors: Benson, R. A.; Patakas, A.; McQueenie, R.; Ross, K.; McInnes, I. B.; Brewer, J. M.; Garside, P.
Source: Self-asserted source
James Brewer via ResearcherID

Characterization of the Anticollagen Antibody Response in a New Model of Chronic Polyarthritis

Arthritis and Rheumatism
2011 | Journal article
DOI: 10.1002/art.30413
WOSUID:

WOS:000293840200020
Contributors: Conigliaro, Paola; Benson, Robert A.; Patakas, Agapitos; Kelly, Sharon M.; Valesini, Guido; Holmdahl, Rikard; Brewer, James M.; McInnes, Iain B.; Garside, Paul
Source: Self-asserted source
James Brewer via ResearcherID

Effect of chromium and cobalt ions on primary human lymphocytes in vitro

Journal of Immunotoxicology
2011 | Journal article
DOI: 10.3109/1547691X.2011.553845
WOSUID:

WOS:000290167000005
Contributors: Akbar, Moeed; Brewer, James M.; Grant, M. Helen
Source: Self-asserted source
James Brewer via ResearcherID

Effects of Streptococcus mutans on Dendritic Cell Activation and Function

Journal of Dental Research
2011 | Journal article
DOI: 10.1177/0022034511412970
WOSUID:

WOS:000294838200013
Contributors: Butcher, J. P.; Malcolm, J.; Benson, R. A.; Deng, D. M.; Brewer, J. M.; Garside, P.; Culshaw, S.
Source: Self-asserted source
James Brewer via ResearcherID

In Vivo Real-Time Multiphoton Imaging of T Lymphocytes in the Mouse Brain After Experimental Stroke

Stroke
2011 | Journal article
DOI: 10.1161/STROKEAHA.110.603704
WOSUID:

WOS:000289835900047
Contributors: Fumagalli, Stefano; Coles, Jonathan A.; Ejlerskov, Patrick; Ortolano, Fabrizio; Bushell, Trevor J.; Brewer, James M.; De Simoni, Maria-Grazia; Dever, Gary; Garside, Paul; Maffia, Pasquale et al.
Source: Self-asserted source
James Brewer via ResearcherID

Putative existence of reciprocal dialogue between Tfh and B cells and its impact on infectious and autoimmune disease

Immunology Letters
2011 | Journal article
DOI: 10.1016/j.imlet.2011.03.002
WOSUID:

WOS:000292714800013
Contributors: Patakas, Agapitos; Platt, Andrew M.; Butcher, John P.; Maffia, Pasquale; McInnes, Iain B.; Brewer, James M.; Garside, Paul; Benson, Robert A.
Source: Self-asserted source
James Brewer via ResearcherID
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