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Works (11)

Guiding the future of clinical care and clinical research in Birt-Hogg-Dubé

European Journal of Human Genetics
2024-12 | Journal article
DOI: 10.1038/s41431-024-01696-7
Contributors: Michel Alchoueiry; W. Clark Lambert; Elizabeth P. Henske
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The Spectrum of Renal “TFEopathies”: Flipping the mTOR Switch in Renal Tumorigenesis

Physiology
2024-11-01 | Journal article
DOI: 10.1152/physiol.00026.2024
Contributors: Nicola Alesi; Kaushal Asrani; Tamara L. Lotan; Elizabeth P. Henske
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Clinical practice recommendations for kidney involvement in tuberous sclerosis complex: a consensus statement by the ERKNet Working Group for Autosomal Dominant Structural Kidney Disorders and the ERA Genes & Kidney Working Group

Nature Reviews Nephrology
2024-06 | Journal article
DOI: 10.1038/s41581-024-00818-0
Contributors: Djalila Mekahli; Roman-Ulrich Müller; Matko Marlais; Tanja Wlodkowski; Stefanie Haeberle; Marta López de Argumedo; Carsten Bergmann; Luc Breysem; Carla Fladrowski; Elizabeth P. Henske et al.
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Bi-steric mTORC1 inhibitors induce apoptotic cell death in tumor models with hyperactivated mTORC1

Journal of Clinical Investigation
2023-11-01 | Journal article
DOI: 10.1172/JCI167861
Contributors: Heng Du; Yu Chi Yang; Heng-Jia Liu; Min Yuan; John M. Asara; Kwok-Kin Wong; Elizabeth P. Henske; Mallika Singh; David J. Kwiatkowski
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Lymphangioleiomyomatosis: circulating levels of FGF23 and pulmonary diffusion

Jornal Brasileiro de Pneumologia
2023-04-03 | Journal article
DOI: 10.36416/1806-3756/e20220356
Contributors: Anthony J Esposito1,2; Jewel Imani1; Shikshya Shrestha1; Shefali Bagwe1; Anthony M Lamattina1; Marina Vivero3; Hilary J Goldberg1; Ivan O Rosas4; Elizabeth P Henske1; Souheil Y El-Chemaly1
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mTORC1 upregulates B7-H3/CD276 to inhibit antitumor T cells and drive tumor immune evasion

Nature Communications
2023-03-03 | Journal article
DOI: 10.1038/s41467-023-36881-7
Contributors: Heng-Jia Liu; Heng Du; Damir Khabibullin; Mahsa Zarei; Kevin Wei; Gordon J. Freeman; David J. Kwiatkowski; Elizabeth P. Henske
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Angiotensin II receptor type 1 blockade regulates Klotho expression to induce TSC2-deficient cell death

Journal of Biological Chemistry
2022-11 | Journal article
DOI: 10.1016/j.jbc.2022.102580
Contributors: Shikshya Shrestha; Elio Adib; Jewel Imani; Dean J. Aguiar; Anthony M. Lamattina; Dereje D. Tassew; Elizabeth P. Henske; Mark A. Perrella; Carmen Priolo; Souheil El-Chemaly
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Keeping up with the Rag GTPases

Nature Cell Biology
2022-09 | Journal article
DOI: 10.1038/s41556-022-00981-1
Contributors: Nicola Alesi; Elizabeth P. Henske
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Midkine expression by stem-like tumor cells drives persistence to mTOR inhibition and an immune-suppressive microenvironment

Nature Communications
2022-08-26 | Journal article
DOI: 10.1038/s41467-022-32673-7
Contributors: Yan Tang; David J. Kwiatkowski; Elizabeth P. Henske
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Lung-selective mRNA delivery of synthetic lipid nanoparticles for the treatment of pulmonary lymphangioleiomyomatosis

Proceedings of the National Academy of Sciences
2022-02-22 | Journal article
DOI: 10.1073/pnas.2116271119
Contributors: Min Qiu; Yan Tang; Jinjin Chen; Rachel Muriph; Zhongfeng Ye; Changfeng Huang; Jason Evans; Elizabeth P. Henske; Qiaobing Xu
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Kidney intercalated cells and the transcription factor FOXi1 drive cystogenesis in tuberous sclerosis complex

Proceedings of the National Academy of Sciences
2021-02-09 | Journal article
DOI: 10.1073/pnas.2020190118
Contributors: Sharon Barone; Kamyar Zahedi; Marybeth Brooks; Elizabeth P. Henske; Yirong Yang; Erik Zhang; John J. Bissler; Jane J. Yu; Manoocher Soleimani
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