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Employment (7)

Children's Hospital of Philadelphia: Philadelphia, PA, US

2017 to present | Section Chief, Cellular Therapy and Transplant (Division of Oncology)
Employment
Source: Self-asserted source
Stephan Grupp

Children's Hospital of Philadelphia: Philadelphia, PA, US

2015 to present | Director, Cancer Immunotherapy Program (Division of Oncology)
Employment
Source: Self-asserted source
Stephan Grupp

University of Pennsylvania: Philadelphia, PA, US

2011 to present | Professor with Tenure (Pediatrics)
Employment
Source: Self-asserted source
Stephan Grupp

Children's Hospital of Philadelphia: Philadelphia, PA, US

2001 to present | Medical Director, Cell and Gene Therapy Lab (Division of Oncology)
Employment
Source: Self-asserted source
Stephan Grupp

Children's Hospital of Philadelphia: Philadelphia, PA, US

1996 to present | Pediatric attending physician (Division of Oncology)
Employment
Source: Self-asserted source
Stephan Grupp

University of Pennsylvania: Philadelphia, PA, US

2006 to 2011 | Associate Professor (Pediatrics)
Employment
Source: Self-asserted source
Stephan Grupp

University of Pennsylvania: Philadelphia, PA, US

1996 to 2006 | Assistant Professor (Pediatrics)
Employment
Source: Self-asserted source
Stephan Grupp

Works (36)

Allogeneic chimeric antigen receptor cell therapies for cancer: progress made and remaining roadblocks

Nature Reviews Clinical Oncology
2025-01 | Journal article
Contributors: Caroline Diorio; David T. Teachey; Stephan A. Grupp
Source: check_circle
Crossref

CD4+ T Cells Mediate Dendritic Cell Licensing to Promote Multi‐Antigen Anti‐Leukemic Immune Response

Cancer Medicine
2025-01 | Journal article
Contributors: Luis Gil‐de‐Gómez; Joseph J. Mattei; Jessica H. Lee; Stephan A. Grupp; Gregor S. D. Reid; Alix E. Seif
Source: check_circle
Crossref

Long-term safety of lentiviral or gammaretroviral gene-modified T cell therapies

Nature Medicine
2025-01-20 | Journal article
Contributors: Julie K. Jadlowsky; Elizabeth O. Hexner; Amy Marshall; Stephan A. Grupp; Noelle V. Frey; James L. Riley; Elizabeth Veloso; Holly McConville; Walter Rogal; Cory Czuczman et al.
Source: check_circle
Crossref

Novel MAGIC composite scores using both clinical symptoms and biomarkers best predict treatment outcomes of acute GVHD

Blood
2024-08-29 | Journal article
Contributors: Yu Akahoshi; Nikolaos Spyrou; Daniela Weber; Paibel Aguayo-Hiraldo; Francis Ayuk; Chantiya Chanswangphuwana; Hannah K. Choe; Matthias Eder; Aaron M. Etra; Stephan A. Grupp et al.
Source: check_circle
Crossref

INSPIRED Symposium Part 5: Expanding the Use of CAR T Cells in Children and Young Adults

Transplantation and Cellular Therapy
2024-06 | Journal article
Contributors: Aimee C. Talleur; Vanessa A. Fabrizio; Richard Aplenc; Stephan A. Grupp; Crystal Mackall; Robbie Majzner; Rosa Nguyen; Rayne Rouce; Amy Moskop; Kevin O. McNerney
Source: check_circle
Crossref

ACT To Sustain: Adoptive Cell Therapy To Sustain Access to Non-Commercialized Genetically Modified Cell Therapies

Transplantation and Cellular Therapy
2024-05 | Journal article
Contributors: Rebecca A. Gardner; Claire White; Magdi Elsallab; Stephanie Farnia; Ellen Fraint; Bambi Grilley; Alison Bateman-House; Stephan A. Grupp; Saad Kenderian; Frederick L. Locke et al.
Source: check_circle
Crossref

Flares of acute graft-versus-host disease: a Mount Sinai Acute GVHD International Consortium analysis

Blood Advances
2024-04-23 | Journal article
Contributors: Yu Akahoshi; Nikolaos Spyrou; Matthias Hoepting; Paibel Aguayo-Hiraldo; Francis Ayuk; Chantiya Chanswangphuwana; Hannah K. Choe; Matthias Eder; Aaron M. Etra; Stephan A. Grupp et al.
Source: check_circle
Crossref

Unanswered questions following reports of secondary malignancies after CAR-T cell therapy

Nature Medicine
2024-02 | Journal article
Contributors: Bruce L. Levine; Marcelo C. Pasquini; John E. Connolly; David L. Porter; Michael P. Gustafson; Jaap J. Boelens; Edwin M. Horwitz; Stephan A. Grupp; Marcela V. Maus; Frederick L. Locke et al.
Source: check_circle
Crossref

INSPIRED Symposium Part 1: Clinical Variables Associated with Improved Outcomes for Children and Young Adults treated with Chimeric Antigen Receptor T cells for B cell Acute Lymphoblastic Leukemia

Transplantation and Cellular Therapy
2023-10 | Journal article
Contributors: Regina M. Myers; Elad Jacoby; Michael A. Pulsipher; Marcelo C. Pasquini; Stephan A. Grupp; Nirali N. Shah; Theodore W. Laetsch; Kevin J. Curran; Liora M. Schultz
Source: check_circle
Crossref

Prevention of veno-occlusive disease/sinusoidal obstruction syndrome: a never-ending story and no easy answer

Bone Marrow Transplantation
2023-08 | Journal article
Contributors: Selim Corbacioglu; Stephan A. Grupp; Paul Gerard Richardson; Rafael Duarte; Antonio Pagliuca; Tapani Ruutu; Kris Mahadeo; Enric Carreras
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Crossref

In vivo hematopoietic stem cell modification by mRNA delivery

Science
2023-07-28 | Journal article
Contributors: Laura Breda; Tyler E. Papp; Michael P. Triebwasser; Amir Yadegari; Megan T. Fedorky; Naoto Tanaka; Osheiza Abdulmalik; Giulia Pavani; Yongping Wang; Stephan A. Grupp et al.
Source: check_circle
Crossref

Reply to W.H. Tong et al

Journal of Clinical Oncology
2023-05-01 | Journal article
Contributors: Theodore W. Laetsch; Ranjan Tiwari; Stephan A. Grupp
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Crossref

Data from Characterization of Leukemic Resistance to CD19-Targeted CAR T-cell Therapy through Deep Genomic Sequencing

2023-04-04 | Preprint
Contributors: Gregory M. Chen; Chia-Hui Chen; Jessica Perazzelli; Stephan A. Grupp; David M. Barrett; Kai Tan
Source: check_circle
Crossref

Data from Characterization of Leukemic Resistance to CD19-Targeted CAR T-cell Therapy through Deep Genomic Sequencing

2023-04-04 | Preprint
Contributors: Gregory M. Chen; Chia-Hui Chen; Jessica Perazzelli; Stephan A. Grupp; David M. Barrett; Kai Tan
Source: check_circle
Crossref

Supplementary Figures from Characterization of Leukemic Resistance to CD19-Targeted CAR T-cell Therapy through Deep Genomic Sequencing

2023-04-04 | Preprint
Contributors: Gregory M. Chen; Chia-Hui Chen; Jessica Perazzelli; Stephan A. Grupp; David M. Barrett; Kai Tan
Source: check_circle
Crossref

Supplementary Figures from Characterization of Leukemic Resistance to CD19-Targeted CAR T-cell Therapy through Deep Genomic Sequencing

2023-04-04 | Preprint
Contributors: Gregory M. Chen; Chia-Hui Chen; Jessica Perazzelli; Stephan A. Grupp; David M. Barrett; Kai Tan
Source: check_circle
Crossref

Supplementary legends from Characterization of Leukemic Resistance to CD19-Targeted CAR T-cell Therapy through Deep Genomic Sequencing

2023-04-04 | Preprint
Contributors: Gregory M. Chen; Chia-Hui Chen; Jessica Perazzelli; Stephan A. Grupp; David M. Barrett; Kai Tan
Source: check_circle
Crossref

Supplementary legends from Characterization of Leukemic Resistance to CD19-Targeted CAR T-cell Therapy through Deep Genomic Sequencing

2023-04-04 | Preprint
Contributors: Gregory M. Chen; Chia-Hui Chen; Jessica Perazzelli; Stephan A. Grupp; David M. Barrett; Kai Tan
Source: check_circle
Crossref

Supplementary Table 1 from Characterization of Leukemic Resistance to CD19-Targeted CAR T-cell Therapy through Deep Genomic Sequencing

2023-04-04 | Preprint
Contributors: Gregory M. Chen; Chia-Hui Chen; Jessica Perazzelli; Stephan A. Grupp; David M. Barrett; Kai Tan
Source: check_circle
Crossref

Supplementary Table 1 from Characterization of Leukemic Resistance to CD19-Targeted CAR T-cell Therapy through Deep Genomic Sequencing

2023-04-04 | Preprint
Contributors: Gregory M. Chen; Chia-Hui Chen; Jessica Perazzelli; Stephan A. Grupp; David M. Barrett; Kai Tan
Source: check_circle
Crossref

Supplementary Table 2 from Characterization of Leukemic Resistance to CD19-Targeted CAR T-cell Therapy through Deep Genomic Sequencing

2023-04-04 | Preprint
Contributors: Gregory M. Chen; Chia-Hui Chen; Jessica Perazzelli; Stephan A. Grupp; David M. Barrett; Kai Tan
Source: check_circle
Crossref

Supplementary Table 2 from Characterization of Leukemic Resistance to CD19-Targeted CAR T-cell Therapy through Deep Genomic Sequencing

2023-04-04 | Preprint
Contributors: Gregory M. Chen; Chia-Hui Chen; Jessica Perazzelli; Stephan A. Grupp; David M. Barrett; Kai Tan
Source: check_circle
Crossref

Automation of Hematopoietic Cell Transplantation Outcomes Reporting Leads to Dramatic Reduction in Errors Reported to Real-World Data Registry

Transplantation and Cellular Therapy
2023-03 | Journal article
Contributors: David S. Anderson; Richard S. Hanna; Amir Reza Pashmina Azar; Victoria Collier; Patricia Hankins; Brandon Loudon; Timothy S. Olson; Stephan A. Grupp; Charles A. Phillips; Stephan Kadauke
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Crossref

Data from Statistical Considerations for Analyses of Time-To-Event Endpoints in Oncology Clinical Trials: Illustrations with CAR-T Immunotherapy Studies

2023-03-31 | Preprint
Contributors: Yimei Li; Wei-Ting Hwang; Shannon L. Maude; David T. Teachey; Noelle V. Frey; Regina M. Myers; Allison Barz Leahy; Hongyan Liu; David L. Porter; Stephan A. Grupp et al.
Source: check_circle
Crossref

Data from Statistical Considerations for Analyses of Time-To-Event Endpoints in Oncology Clinical Trials: Illustrations with CAR-T Immunotherapy Studies

2023-03-31 | Preprint
Contributors: Yimei Li; Wei-Ting Hwang; Shannon L. Maude; David T. Teachey; Noelle V. Frey; Regina M. Myers; Allison Barz Leahy; Hongyan Liu; David L. Porter; Stephan A. Grupp et al.
Source: check_circle
Crossref

Supplementary Data from Statistical Considerations for Analyses of Time-To-Event Endpoints in Oncology Clinical Trials: Illustrations with CAR-T Immunotherapy Studies

2023-03-31 | Preprint
Contributors: Yimei Li; Wei-Ting Hwang; Shannon L. Maude; David T. Teachey; Noelle V. Frey; Regina M. Myers; Allison Barz Leahy; Hongyan Liu; David L. Porter; Stephan A. Grupp et al.
Source: check_circle
Crossref

Supplementary Data from Statistical Considerations for Analyses of Time-To-Event Endpoints in Oncology Clinical Trials: Illustrations with CAR-T Immunotherapy Studies

2023-03-31 | Preprint
Contributors: Yimei Li; Wei-Ting Hwang; Shannon L. Maude; David T. Teachey; Noelle V. Frey; Regina M. Myers; Allison Barz Leahy; Hongyan Liu; David L. Porter; Stephan A. Grupp et al.
Source: check_circle
Crossref

Supplementary Table from Statistical Considerations for Analyses of Time-To-Event Endpoints in Oncology Clinical Trials: Illustrations with CAR-T Immunotherapy Studies

2023-03-31 | Preprint
Contributors: Yimei Li; Wei-Ting Hwang; Shannon L. Maude; David T. Teachey; Noelle V. Frey; Regina M. Myers; Allison Barz Leahy; Hongyan Liu; David L. Porter; Stephan A. Grupp et al.
Source: check_circle
Crossref

Supplementary Table from Statistical Considerations for Analyses of Time-To-Event Endpoints in Oncology Clinical Trials: Illustrations with CAR-T Immunotherapy Studies

2023-03-31 | Preprint
Contributors: Yimei Li; Wei-Ting Hwang; Shannon L. Maude; David T. Teachey; Noelle V. Frey; Regina M. Myers; Allison Barz Leahy; Hongyan Liu; David L. Porter; Stephan A. Grupp et al.
Source: check_circle
Crossref

Supplementary Table from Statistical Considerations for Analyses of Time-To-Event Endpoints in Oncology Clinical Trials: Illustrations with CAR-T Immunotherapy Studies

2023-03-31 | Preprint
Contributors: Yimei Li; Wei-Ting Hwang; Shannon L. Maude; David T. Teachey; Noelle V. Frey; Regina M. Myers; Allison Barz Leahy; Hongyan Liu; David L. Porter; Stephan A. Grupp et al.
Source: check_circle
Crossref

Supplementary Table from Statistical Considerations for Analyses of Time-To-Event Endpoints in Oncology Clinical Trials: Illustrations with CAR-T Immunotherapy Studies

2023-03-31 | Preprint
Contributors: Yimei Li; Wei-Ting Hwang; Shannon L. Maude; David T. Teachey; Noelle V. Frey; Regina M. Myers; Allison Barz Leahy; Hongyan Liu; David L. Porter; Stephan A. Grupp et al.
Source: check_circle
Crossref

Characterization of Leukemic Resistance to CD19-Targeted CAR T-cell Therapy through Deep Genomic Sequencing

Cancer Immunology Research
2023-01-03 | Journal article
Contributors: Gregory M. Chen; Chia-Hui Chen; Jessica Perazzelli; Stephan A. Grupp; David M. Barrett; Kai Tan
Source: check_circle
Crossref

Statistical Considerations for Analyses of Time-To-Event Endpoints in Oncology Clinical Trials: Illustrations with CAR-T Immunotherapy Studies

Clinical Cancer Research
2022-09-15 | Journal article
Contributors: Yimei Li; Wei-Ting Hwang; Shannon L. Maude; David T. Teachey; Noelle V. Frey; Regina M. Myers; Allison Barz Leahy; Hongyan Liu; David L. Porter; Stephan A. Grupp et al.
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Crossref

Mesenchymal stromal cell therapy induces high responses and survival in children with steroid refractory GVHD and poor risk biomarkers

Bone Marrow Transplantation
2021-11-01 | Journal article
Contributors: Stelios Kasikis; Janna Baez; Isha Gandhi; Stephan Grupp; Carrie L. Kitko; Steven Kowalyk; Pietro Merli; George Morales; Michael A. Pulsipher; Muna Qayed et al.
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Crossref

Will allogeneic CAR T cells for CD19+ malignancies take autologous CAR T cells ‘off the shelf’?

Nature Reviews Clinical Oncology
2021-04 | Journal article
Contributors: Amanda M. DiNofia; Stephan A. Grupp
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Practical guidelines for monitoring and management of coagulopathy following tisagenlecleucel CAR T-cell therapy

Blood Advances
2021-01-26 | Journal article
Contributors: Jochen Buechner; Stephan A. Grupp; Hidefumi Hiramatsu; David T. Teachey; Susana Rives; Theodore W. Laetsch; Gregory A. Yanik; Patricia Wood; Rakesh Awasthi; Lan Yi et al.
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Peer review (4 reviews for 4 publications/grants)

Review activity for Nature cancer. (1)
Review activity for Nature communications (1)
Review activity for Nature immunology. (1)
Review activity for Nature reviews. (1)