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Employment (2)

Chengdu Medical College: Chengdu, Sichuan, CN

2021-06-01 to present | Associate Professor (Department of Cardiothoracic Surgery，First Affiliated Hospital of Chengdu Medical College)
Employment
Source: Self-asserted source
Hu Chen

Sichuan University : Chengdu, Sichuan, CN

2017-02-24 to 2021-05-31 (School of Life Sciences)
Employment
Source: Self-asserted source
Hu Chen

Education and qualifications (2)

Sun Yat-Sen University: Guangzhou, Guangdong, CN

2013-08-21 to 2016-09-03 | PhD (School of Life Sciences)
Education
Source: Self-asserted source
Hu Chen

Sun Yat-Sen University: Guangzhou, Guangdong, CN

2010-09-01 to 2013-07-01 | Master (School of Life Sciences)
Education
Source: Self-asserted source
Hu Chen

Works (13)

ΔNp63α promotes radioresistance in esophageal squamous cell carcinoma through the PLEC-KEAP1-NRF2 feedback loop.

Cell death & disease
2024-11-05 | Journal article | Author
DOI: 10.1038/s41419-024-07194-4
PMID: 39500864
PMC: PMC11538512
Contributors: Tao J; Mao M; Lu Y; Deng L; Yu S; Zeng X; Jia W; Wu Z; Chenghua Li; Ma R et al.
Source: Self-asserted source
Hu Chen

Primary Lung Squamous Cell Carcinoma With Intestinal Metastasis: A Case Report and Literature Review

The Clinical Respiratory Journal
2024-08 | Journal article
DOI: 10.1111/crj.13817
Contributors: Jin Tao; Zhiqiang Wu; Rongfei Huang; Jun Li; Tiewei Xu; Yujie Gao; Weikun Jia; Hu Chen
Source: check_circle
Crossref

Comparative proteomics reveals that fatty acid metabolism is involved in myocardial adaptation to chronic hypoxic injury

PLOS ONE
2024-06-17 | Journal article
DOI: 10.1371/journal.pone.0305571
Contributors: Hu Chen; Partha Mukhopadhyay; Shiran Yu; Xiaoyun Zhang; Yujie Gao; Hongqi Wang; Yuankun Li; Dongsheng He; Weikun Jia
Source: check_circle
Crossref

Hypoxia-activated XBP1s recruits HDAC2-EZH2 to engage epigenetic suppression of ΔNp63α expression and promote breast cancer metastasis independent of HIF1α

Cell Death & Differentiation
2024-04 | Journal article
DOI: 10.1038/s41418-024-01271-z
Contributors: Hu Chen; Shuhan Yu; Ruidong Ma; Liyuan Deng; Yong Yi; Mengmeng Niu; Chuan Xu; Zhi-Xiong Jim Xiao
Source: check_circle
Crossref

CCT8 promotes cell migration and tumor metastasis in lung adenocarcinomas.

Journal of Cancer
2023-10-02 | Journal article
DOI: 10.7150/jca.87983
PMID: 37928427
Contributors: Wu Z; Deng L; Tao J; Lu Y; Zeng X; Jia W; Chen H
Source: Self-asserted source
Hu Chen

ER stress activates TAp73α to promote colon cancer cell apoptosis via the PERK-ATF4 pathway.

Journal of Cancer
2023-07-03 | Journal article
DOI: 10.7150/jca.84170
PMID: 37497416
Contributors: Sun S; Yi Y; Xiao ZJ; Chen H
Source: Self-asserted source
Hu Chen

E47 upregulates ΔNp63α to promote growth of squamous cell carcinoma

Cell Death & Disease
2021-04-08 | Journal article
DOI: 10.1038/s41419-021-03662-3
Contributors: Jing Xu; Fengtian Li; Ya Gao; Rongtian Guo; Liangping Ding; Mengyuan Fu; Yong Yi; Hu Chen; Zhi-Xiong Jim Xiao; Mengmeng Niu
Source: check_circle
Crossref

Hotspot mutant p53-R273H inhibits KLF6 expression to promote cell migration and tumor metastasis

Cell Death & Disease
2020-07-30 | Journal article
DOI: 10.1038/s41419-020-02814-1
Contributors: Shengnan Sun; Hu Chen; Lijuan Sun; Miao Wang; Xianqiang Wu; Zhi-Xiong Jim Xiao
Source: check_circle
Crossref

HER2 Upregulates ATF4 to Promote Cell Migration via Activation of ZEB1 and Downregulation of E-Cadherin

International Journal of Molecular Sciences
2019-05-06 | Journal article
DOI: 10.3390/ijms20092223
Contributors: Peng Zeng; Shengnan Sun; Rui Li; Zhi-Xiong Xiao; Hu Chen
Source: check_circle
Crossref

ΔNp63α is a common inhibitory target in oncogenic PI3K/Ras/Her2-induced cell motility and tumor metastasis

Proc Natl Acad Sci U S A
2017-05-16 | Journal article
DOI: 10.1073/pnas.1617816114
PMID: 28468801
Source: Self-asserted source
Hu Chen

ATF4 regulates SREBP1c expression to control fatty acids synthesis in 3T3-L1 adipocytes differentiation

BBA-Gene Regulatory Mechanism
2016-07-20 | Journal article
DOI: 10.1016/j.bbagrm.2016.07.010
PMID: 27452504
Source: Self-asserted source
Hu Chen

miR-709 inhibits 3T3-L1 cell differentiation by targeting GSK3β of Wnt/β-catenin signaling

Cellular Signalling
2014-07-20 | Journal article
DOI: 10.1016/j.cellsig.2014.07.017
PMID: 25038456
Source: Self-asserted source
Hu Chen

MicroRNA-344 inhibits 3T3-L1 cell differentiation via targeting GSK3β of Wnt/β-catenin signaling pathway

FEBS Letters
2013-12-10 | Journal article
DOI: 10.1016/j.febslet.2013.12.002
PMID: 24333578
Source: Self-asserted source
Hu Chen

Peer review (3 reviews for 2 publications/grants)

Review activity for Advanced science. (1)
Review activity for World journal of surgical oncology (2)
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