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Inflammasomes, Exposomes, TRPV4, Lung Physiology, Mitochondria
United States

Biography

Diego F. Alvarez, M.D., Ph.D. - Physiology Leader & Innovator | Advancing Medical Education & Medical Research

Leadership in Action.

I am a newly appointed clinical professor of physiology in the Department of Biomedical Sciences at the Tilman J. Fertitta Family College of Medicine. With 30 years of experience in academic settings, my career has been dedicated to developing and leading healthcare and medical educational infrastructures in university environments. As Health and Medical Care Director, I fostered interprofessional programs, leading over twenty professionals and supporting staff while also practicing medicine.

I founded and developed the foundational science department, serving as Chair of the Department of Physiology and Pharmacology, where I oversaw six faculty members and their supporting staff. My pioneering efforts in curriculum mapping and teaching integrated physiology and system-based learning have enhanced medical education significantly. I excel in directing system-based, cohesive biomedical/clinical medicine courses, promoting a comprehensive understanding of physiology integrated with clinical applications.

Expertise & Research.

My research focuses on elucidating mechanisms underlying pulmonary edema, investigating stress responses in pulmonary endothelial cells, and exploring pulmonary vascular repair by endothelial progenitor cells. My work on stress-induced amyloids and host responses activating inflammasomes has led to the discovery of novel treatment pathways for pulmonary edema and myocardial infarction, with intellectual property products in the pipeline for clinical trials. This innovative research has been supported by prominent institutions such as the National Institutes of Health (NIH) and the American Heart Association (AHA). More recently, my work has involved studying exposomes, including how community quality of life affects human health. I have published over fifty peer-reviewed original articles in indexed journals and regularly present scientific abstracts at professional meetings.

Impact & Recognition.

I have received over twenty awards and recognitions, including being a founding member of undergraduate and graduate health programs. As a clinical practitioner, I was recognized with an “Excellence in Health Care Practice” award. For my teaching abilities, I have received multiple accolades, including the "Top Prof Distinguished Member of the University Community" award from the Mortar Board Senior Honor Society and the esteemed "Red Sash Award for Distinguished Faculty" from the University of South Alabama Medical Students. During my tenure at Sam Houston State University, I was honored with tenure and recently received the 2024 “Excellence in Teaching Award” from the student body at Sam Houston State University College of Osteopathic Medicine. I have mentored over twenty junior faculty, helping them achieve program independence as researchers and progress through the academic promotion and tenure ladder. I have been recognized by my peers and contributed to serving as a study section reviewer for the NIH, a member of the editorial board for two medical journals and serving in leadership roles at The American Physiological Society (APS), and The American Thoracic Society (ATS).

Educational background.

I earned my medical degree from La Universidad Libre in Cali, Colombia in 1994 and my Ph.D. in basic medical sciences (physiology) from the University of South Alabama in 2005 under the mentorship of Mary Townsley and Aubrey Taylor. I completed my postdoctoral fellowship in 2007 at the University of South Alabama under the mentorship of Dr. Troy Stevens.

Looking Forward.

In my current role, I am committed to developing scholarly infrastructure to address health disparities and understand the impact of environmental factors (exposomes) on public health in Southeast Texas while training the next generation of physicians.

For 30 years, I have served as a visionary leader in medical education and scientific discovery. As a Clinical Professor of Physiology at Tilman J. Fertitta Family College of Medicine I am enthusiastic about fostering a comprehensive understanding of physiology for future healthcare professionals.

Activities

Employment (4)

University of Houston: Houston, Texas, US

2024-05-15 to present | Clinical Professor of Physiology (Biomedical Sciences)
Employment
Source: Self-asserted source
Diego F. Alvarez MD, PhD

Sam Houston State University: Conroe, Texas, US

2019-06-01 to 2024-05-14 | Chair and Professor (Physiology and Pharmacology)
Employment
Source: Self-asserted source
Diego F. Alvarez MD, PhD

University of South Alabama: Mobile, Alabama, US

2015-10-01 to 2019-05-31 | Associate Professor (Physiology & Cell Biology)
Employment
Source: Self-asserted source
Diego F. Alvarez MD, PhD

University of South Alabama: Mobile, US

2007 to 2015 | Assistant Professor (Internal Medicine and Pharmacology)
Employment
Source: Self-asserted source
Diego F. Alvarez MD, PhD

Education and qualifications (4)

University of South Alabama College of Medicine: Mobile, AL, US

2005 to 2007 | Postdoctoral fellow (Center for Lung Biology)
Education
Source: Self-asserted source
Diego F. Alvarez MD, PhD

University of South Alabama College of Medicine: Mobile, AL, US

2000 to 2005 | PhD in Basic Medical Sciences (Physiology) (Physiology & Cell Biology)
Education
Source: Self-asserted source
Diego F. Alvarez MD, PhD

Universidad Santiago de Cali: Cali, Valle, CO

1997 to 1998 | Diploma/Certificate Institutional Educational Project
Education
Source: Self-asserted source
Diego F. Alvarez MD, PhD

Universidad Libre - Cali: Cali, Valle, CO

1988 to 1994 | MD (College of Medicine)
Education
Source: Self-asserted source
Diego F. Alvarez MD, PhD

Funding (4)

Caspase-1, the Microvascular Endothelium, and Infection

2015-04-01 to 2020-03-31 | Grant
National Heart Lung and Blood Institute (Bethesda, US)
GRANT_NUMBER: R01HL118334
Source: Self-asserted source
Diego F. Alvarez MD, PhD via DimensionsWizard

Infusion of resident endothelial progenitors promotes repair of microvascular barrier during acute lung injury

2008-07-01 to 2012-06-30 | Grant
American Heart Association (Dallas, US)
GRANT_NUMBER:

0835134N

Source: Self-asserted source
Diego F. Alvarez MD, PhD via DimensionsWizard

Role of P450 arachidonic acid metabolites in regulation of pulmonary endothelial cell permeability

2003-07-01 to 2005-07-30 | Grant
American Heart Association (Dallas, US)
GRANT_NUMBER:

0315049B

Source: Self-asserted source
Diego F. Alvarez MD, PhD via DimensionsWizard

Lung endothelial cell phenotypes

2000-12-01 to 2023-04-30 | Grant
National Heart Lung and Blood Institute (Bethesda, US)
GRANT_NUMBER: P01HL066299
Source: Self-asserted source
Diego F. Alvarez MD, PhD via DimensionsWizard

Works (50 of 58)

Items per page:
Page 1 of 2

Studying the Pulmonary Endothelium in Health and Disease: An Official American Thoracic Society Workshop Report

American Journal of Respiratory Cell and Molecular Biology
2024-10 | Journal article
Contributors: Rebecca F. Hough; Cristina M. Alvira; Julie A. Bastarache; Serpil C. Erzurum; Wolfgang M. Kuebler; Eric P. Schmidt; Larissa A. Shimoda; Steven H. Abman; Diego F. Alvarez; Patrick Belvitch et al.
Source: check_circle
Crossref
grade
Preferred source (of 2)‎

Endothelial Heterogeneity in the Response to Autophagy Drives Small Vessel Muscularization in Pulmonary Hypertension.

Circulation
2024-06-14 | Journal article | Author
Contributors: Qi Zhang; Yaoita N; Tabuchi A; Shao-Fei Liu; Shiau-Haln Chen; Li Q; Hegemann N; Li C; Julie RODOR; Sara Timm et al.
Source: Self-asserted source
Diego F. Alvarez MD, PhD

Tau and Aβ42 in lavage fluid of pneumonia patients are associated with end-organ dysfunction: A prospective exploratory study.

PloS one
2024-02-23 | Journal article | Author
Contributors: Renema P; Jean-Francois Pittet; Brandon AP; Leal SM Jr; Gu S; Promer G; Hackney A; Braswell P; Pickering A; Rafield G et al.
Source: Self-asserted source
Diego F. Alvarez MD, PhD

Amyloid-β and caspase-1 are indicators of sepsis and organ injury.

ERJ open research
2024-01-01 | Journal article
Contributors: Tuckey AN; Brandon A; Eslaamizaad Y; Siddiqui W; Nawaz T; Clarke C; Sutherland E; Williams V; Spadafora D; Barrington RA et al.
Source: Self-asserted source
Diego F. Alvarez MD, PhD

Integrative Toolkit to Analyze Cellular Signals: Forces, Motion, Morphology, and Fluorescence.

Journal of visualized experiments : JoVE
2022-03-05 | Journal article
Contributors: Nguyen A; Battle K; Paudel SS; Xu N; Bell J; Ayers L; Chapman C; Ajay Pratap Singh; Palanki S; Rich T et al.
Source: Self-asserted source
Diego F. Alvarez MD, PhD

ExoU Induces Lung Endothelial Cell Damage and Activates Pro-Inflammatory Caspase-1 during <i>Pseudomonas aeruginosa</i> Infection

Toxins
2022-02 | Journal article | Author
Contributors: Kierra S. Hardy; Amanda Tuckey; Phoibe Renema; Mita Patel; Abu-Bakr Al-Mehdi; Domenico Spadafora; Cody A. Schlumpf; Robert A. Barrington; Mikhail F. Alexeyev; Troy Stevens et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute

Carbonic Anhydrase IX and Hypoxia Promote Rat Pulmonary Endothelial Cell Survival during Infection

American Journal of Respiratory Cell and Molecular Biology
2021-12 | Journal article
Part of ISSN: 1044-1549
Part of ISSN: 1535-4989
Source: Self-asserted source
Diego F. Alvarez MD, PhD

Engineering Functional Vasculature in Decellularized Lungs Depends on Comprehensive Endothelial Cell Tropism.

Frontiers in bioengineering and biotechnology
2021-08-16 | Journal article
Source: Self-asserted source
Diego F. Alvarez MD, PhD

Development of an endothelial cell restricted transgenic reporter rat: A resource for physiological studies of vascular biology.

American journal of physiology. Heart and circulatory physiology
2020-06-26 | Journal article
Source: Self-asserted source
Diego F. Alvarez MD, PhD

cAMP signaling primes lung endothelial cells to activate caspase-1 during Pseudomonas aeruginosa infection

American Journal of Physiology-Lung Cellular and Molecular Physiology
2020-03-18 | Journal article
Part of ISSN: 1040-0605
Part of ISSN: 1522-1504
Source: Self-asserted source
Diego F. Alvarez MD, PhD

Unleashing shear: Role of intercellular traction and cellular moments in collective cell migration.

Biochemical and biophysical research communications
2019-12-24 | Journal article
Source: Self-asserted source
Diego F. Alvarez MD, PhD

Mechanical signaling in a pulmonary microvascular endothelial cell monolayer.

Biochemical and biophysical research communications
2019-09-09 | Journal article
Source: Self-asserted source
Diego F. Alvarez MD, PhD

Ticagrelor Does Not Protect Isolated Rat Hearts, Thus Clouding Its Proposed Cardioprotective Role Through ENT 1 in Heart Tissue.

Journal of cardiovascular pharmacology and therapeutics
2019-02-11 | Journal article
Source: Self-asserted source
Diego F. Alvarez MD, PhD

Analysis of pulmonary vascular injury and repair during Pseudomonas aeruginosa infection-induced pneumonia and acute respiratory distress syndrome.

Pulmonary circulation
2019-01-01 | Journal article
Source: Self-asserted source
Diego F. Alvarez MD, PhD

Caspase-1 inhibition by VX-765 administered at reperfusion in P2Y<inf>12</inf> receptor antagonist-treated rats provides long-term reduction in myocardial infarct size and preservation of ventricular function

Basic Research in Cardiology
2018 | Journal article
EID:

2-s2.0-85049809862

Contributors: Audia, J.P.; Yang, X.-M.; Crockett, E.S.; Housley, N.; Haq, E.U.; O’Donnell, K.; Cohen, M.V.; Downey, J.M.; Alvarez, D.F.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Nosocomial pneumonia elicits an endothelial proteinopathy: Evidence for a source of neurotoxic amyloids in critically ill patients

American Journal of Respiratory and Critical Care Medicine
2018 | Journal article
EID:

2-s2.0-85058789560

Contributors: Lin, M.T.; Balczon, R.; Pittet, J.-F.; Wagener, B.M.; Moser, S.A.; Morrow, K.A.; Voth, S.; Francis, C.M.; Leavesley, S.; Bell, J. et al.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Re-endothelialization of rat lung scaffolds through passive, gravity-driven seeding of segment-specific pulmonary endothelial cells

Journal of Tissue Engineering and Regenerative Medicine
2018 | Journal article
EID:

2-s2.0-85019047870

Contributors: Scarritt, M.E.; Pashos, N.C.; Motherwell, J.M.; Eagle, Z.R.; Burkett, B.J.; Gregory, A.N.; Mostany, R.; Weiss, D.J.; Alvarez, D.F.; Bunnell, B.A.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

The Highly Selective Caspase-1 Inhibitor VX-765 Provides Additive Protection Against Myocardial Infarction in Rat Hearts When Combined with a Platelet Inhibitor

Journal of Cardiovascular Pharmacology and Therapeutics
2017 | Journal article
EID:

2-s2.0-85029913554

Contributors: Yang, X.-M.; Downey, J.M.; Cohen, M.V.; Housley, N.A.; Alvarez, D.F.; Audia, J.P.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Caspase-1 activation protects lung endothelial barrier function during infection-induced stress

American Journal of Respiratory Cell and Molecular Biology
2016 | Journal article
EID:

2-s2.0-84992371727

Contributors: Alvarez, D.F.; Housley, N.; Koloteva, A.; Zhou, C.; O'Donnell, K.; Audia, J.P.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Evaluation of Microvascular Perfusion and Resuscitation after Severe Injury

The American surgeon
2015 | Journal article
EID:

2-s2.0-84966415676

Contributors: Lee, Y.-L.L.; Simmons, J.D.; Gillespie, M.N.; Alvarez, D.F.; Gonzalez, R.P.; Brevard, S.B.; Frotan, M.A.; Schneider, A.M.; Richards, W.O.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

A novel vascular homing peptide strategy to selectively enhance pulmonary drug efficacy in pulmonary arterial hypertension

American Journal of Pathology
2014 | Journal article
EID:

2-s2.0-84892367888

Contributors: Toba, M.; Alzoubi, A.; O'Neill, K.; Abe, K.; Urakami, T.; Komatsu, M.; Alvarez, D.; Järvinen, T.A.H.; Mann, D.; Ruoslahti, E. et al.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Bariatric surgery improves the circulating numbers and biological activity of late outgrowth endothelial progenitor cells

Surgery for Obesity and Related Diseases
2014 | Journal article
EID:

2-s2.0-84928793857

Contributors: Richards, W.O.; Prutzman, K.B.; O'Hea, M.F.; Audia, J.P.; Alvarez, D.F.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Excitation-scanning hyperspectral imaging microscope

Journal of Biomedical Optics
2014 | Journal article
EID:

2-s2.0-84898453625

Contributors: Favreau, P.F.; Hernandez, C.; Heaster, T.; Alvarez, D.F.; Rich, T.C.; Prabhat, P.; Leavesley, S.J.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

The Pseudomonas aeruginosa exoenzyme Y impairs endothelial cell proliferation and vascular repair following lung injury

American Journal of Physiology - Lung Cellular and Molecular Physiology
2014 | Journal article
EID:

2-s2.0-84900807344

Contributors: Stevens, T.C.; Ochoa, C.D.; Morrow, K.A.; Robson, M.J.; Prasain, N.; Zhou, C.; Alvarez, D.F.; Frank, D.W.; Balczon, R.; Stevens, T.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Thin-film tunable filters for hyperspectral fluorescence microscopy

Journal of Biomedical Optics
2014 | Journal article
EID:

2-s2.0-84887251702

Contributors: Favreau, P.; Hernandez, C.; Lindsey, A.S.; Alvarez, D.F.; Rich, T.; Prabhat, P.; Leavesley, S.J.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Alteration of mitochondrial function and insulin sensitivity in primary mouse skeletal muscle cells isolated from transgenic and knockout mice: Role of OGG1

Endocrinology
2013 | Journal article
EID:

2-s2.0-84880650785

Contributors: Yuzefovych, L.V.; Schuler, A.M.; Chen, J.; Alvarez, D.F.; Eide, L.; LeDoux, S.P.; Wilson, G.L.; Rachek, L.I.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

An approach for characterizing and comparing hyperspectral microscopy systems

Sensors (Switzerland)
2013 | Journal article
EID:

2-s2.0-84880958091

Contributors: Annamdevula, N.S.; Sweat, B.; Favreau, P.; Lindsey, A.S.; Alvarez, D.F.; Rich, T.C.; Leavesley, S.J.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Bariatric surgery rapidly improves mitochondrial respiration in morbidly obese patients

Surgical Endoscopy
2013 | Journal article
EID:

2-s2.0-84890125598

Contributors: Nijhawan, S.; Richards, W.; O'Hea, M.F.; Audia, J.P.; Alvarez, D.F.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Dysfunctional resident lung mesenchymal stem cells contribute to pulmonary microvascular remodeling

Pulmonary Circulation
2013 | Journal article
EID:

2-s2.0-84890032027

Contributors: Chow, K.; Fessel, J.P.; Kaoriihida-Stansbury; Schmidt, E.P.; Gaskill, C.; Alvarez, D.; Graham, B.; Harrison, D.G.; Wagner, D.H.; Nozik-Grayck, E. et al.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

In the absence of effector proteins, the Pseudomonas aeruginosa type three secretion system needle tip complex contributes to lung injury and systemic inflammatory responses

PLoS ONE
2013 | Journal article
EID:

2-s2.0-84896716494

Contributors: Audia, J.P.; Lindsey, A.S.; Housley, N.A.; Ochoa, C.R.; Zhou, C.; Toba, M.; Oka, M.; Annamdevula, N.S.; Fitzgerald, M.S.; Frank, D.W. et al.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Lactate Dehydrogenase A Expression Is Necessary to Sustain Rapid Angiogenesis of Pulmonary Microvascular Endothelium

PLoS ONE
2013 | Journal article
EID:

2-s2.0-84884611017

Contributors: Parra-Bonilla, G.; Alvarez, D.F.; Alexeyev, M.; Vasauskas, A.; Stevens, T.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Hyperspectral imaging microscopy for identification and quantitative analysis of fluorescently-labeled cells in highly autofluorescent tissue

Journal of Biophotonics
2012 | Journal article
EID:

2-s2.0-83155184659

Contributors: Leavesley, S.J.; Annamdevula, N.; Boni, J.; Stocker, S.; Grant, K.; Troyanovsky, B.; Rich, T.C.; Alvarez, D.F.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Terminal sialic acids are an important determinant of pulmonary endothelial barrier integrity

American Journal of Physiology - Lung Cellular and Molecular Physiology
2012 | Journal article
EID:

2-s2.0-84861172289

Contributors: Cioffi, D.L.; Pandey, S.; Alvarez, D.F.; Cioff, E.A.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Comparision of hyper-spectral wide-field and confocal fluorescence microscopic techniques

Food, Pharmaceutical and Bioengineering Division - Core Programming Topic at the 2011 AIChE Annual Meeting
2011 | Conference paper
EID:

2-s2.0-85054882239

Contributors: Annamdevula, N.S.; Stringfellow, A.; Alvarez, D.; Rich, T.C.; Leavesley, S.J.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Heterogeneous activation of p19<sup>Arf</sup>in pulmonary artery smooth muscle cells

American Journal of Physiology - Lung Cellular and Molecular Physiology
2011 | Journal article
EID:

2-s2.0-79955052176

Contributors: Solodushko, V.; Alvarez, D.F.; Viator, R.; Messerall, T.; Fouty, B.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Monitoring physiology trainee needs to focus professional society responses: The APS Trainee Needs surveys

American Journal of Physiology - Advances in Physiology Education
2011 | Journal article
EID:

2-s2.0-79958696668

Contributors: Matyas, M.L.; Lowy, M.E.; Sweazea, K.L.; Alvarez, D.F.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Critical role for lactate dehydrogenase A in aerobic glycolysis that sustains pulmonary microvascular endothelial cell proliferation

American Journal of Physiology - Lung Cellular and Molecular Physiology
2010 | Journal article
EID:

2-s2.0-77957368245

Contributors: Parra-Bonilla, G.; Alvarez, D.F.; Al-Mehdi, A.-B.; Alexeyev, M.; Stevens, T.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Human embryonic stem cell-derived vascular progenitor cells capable of endothelial and smooth muscle cell function

Experimental Hematology
2010 | Journal article
EID:

2-s2.0-76749091589

Contributors: Hill, K.L.; Obrtlikova, P.; Alvarez, D.F.; King, J.A.; Keirstead, S.A.; Allred, J.R.; Kaufman, D.S.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Mechanisms of transcriptional regulation and prognostic significance of activated leukocyte cell adhesion molecule in cancer

Molecular Cancer
2010 | Journal article
EID:

2-s2.0-77957349771

Contributors: King, J.A.; Tan, F.; Mbeunkui, F.; Chambers, Z.; Cantrell, S.; Chen, H.; Alvarez, D.; Shevde, L.A.; Ofori-Acquah, S.F.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Perivascular fluid cuffs decrease lung compliance by increasing tissue resistance

Critical Care Medicine
2010 | Journal article
EID:

2-s2.0-77953081693

Contributors: Lowe, K.; Alvarez, D.F.; King, J.A.; Stevens, T.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Publishing flow cytometry data

American Journal of Physiology - Lung Cellular and Molecular Physiology
2010 | Journal article
EID:

2-s2.0-74949118948

Contributors: Alvarez, D.F.; Helm, K.; DeGregori, J.; Roederer, M.; Majka, S.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Neovascular capacity of endothelial progenitor cells in the adult pulmonary circulation

American Journal of Physiology - Lung Cellular and Molecular Physiology
2009 | Journal article
EID:

2-s2.0-67049118243

Contributors: Majka, S.; Alvarez, D.F.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

TRPing on the lung endothelium: Calcium channels that regulate barrier function

Antioxidants and Redox Signaling
2009 | Journal article
EID:

2-s2.0-60749126088

Contributors: Cioffi, D.L.; Lowe, K.; Alvarez, D.F.; Barry, C.; Stevens, T.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Type 5 phosphodiesterase expression is a critical determinant of the endothelial cell angiogenic phenotype

American Journal of Physiology - Lung Cellular and Molecular Physiology
2009 | Journal article
EID:

2-s2.0-59449085665

Contributors: Zhu, B.; Zhang, L.; Alexeyev, M.; Alvarez, D.F.; Strada, S.J.; Stevens, T.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Lung microvascular endothelium is enriched with progenitor cells that exhibit vasculogenic capacity

American Journal of Physiology - Lung Cellular and Molecular Physiology
2008 | Journal article
EID:

2-s2.0-41549140757

Contributors: Alvarez, D.F.; Huang, L.; King, J.A.; Elzarrad, M.K.; Yoder, M.C.; Stevens, T.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Lung vascular cell heterogeneity: Endothelium, smooth muscle, and fibroblasts

Proceedings of the American Thoracic Society
2008 | Journal article
EID:

2-s2.0-50849085475

Contributors: Stevens, T.; Phan, S.; Frid, M.G.; Alvarez, D.; Herzog, E.; Stenmark, K.R.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Quantum dots - Utilization in TEM

Microscopy and Microanalysis
2008 | Journal article
EID:

2-s2.0-49549085519

Contributors: King, J.; Agarwal, S.; Syklawer, E.; Prasain, N.; Chen, H.; Resmondo, J.; McDonald, F.; Bauer, N.; Alvarez, D.; Wu, S. et al.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Regulatory role for nucleosome assembly protein-1 in the proliferative and vasculogenic phenotype of pulmonary endothelium

American Journal of Physiology - Lung Cellular and Molecular Physiology
2008 | Journal article
EID:

2-s2.0-41549100928

Contributors: Clark, J.; Alvarez, D.F.; Alexeyev, M.; King, J.A.C.; Huang, L.; Yoder, M.C.; Stevens, T.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Thrombin enhances the barrier function of rat microvascular endothelium in a PAR-1-dependent manner

American Journal of Physiology - Lung Cellular and Molecular Physiology
2008 | Journal article
EID:

2-s2.0-39149129997

Contributors: Troyanovsky, B.; Alvarez, D.F.; King, J.A.; Schaphorst, K.L.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier

Phenotypic Heterogeneity in Lung Capillary and Extra-Alveolar Endothelial Cells. Increased Extra-Alveolar Endothelial Permeability is Sufficient to Decrease Compliance

Journal of Surgical Research
2007 | Journal article
EID:

2-s2.0-35248893990

Contributors: Lowe, K.; Alvarez, D.; King, J.; Stevens, T.
Source: Self-asserted source
Diego F. Alvarez MD, PhD via Scopus - Elsevier
Items per page:
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