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Scopus Author ID: 6602153219

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Queen Elizabeth Hospital: Woodville South, SA, AU

Team Leader (Oncology)
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Jennifer Hardingham

Works (50 of 65)

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Page 1 of 2

Differential antiangiogenic and anticancer activities of the active metabolites of ginsenoside Rg3

Journal of Ginseng Research
2024-03 | Journal article
DOI: 10.1016/j.jgr.2021.05.008
Contributors: Maryam Nakhjavani; Eric Smith; Kenny Yeo; Yoko Tomita; Timothy J. Price; Andrea Yool; Amanda R. Townsend; Jennifer E. Hardingham
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Data from Phase IB/II Study of Second-Line Therapy with Panitumumab, Irinotecan, and Everolimus (PIE) in <i>KRAS</i> Wild-Type Metastatic Colorectal Cancer

2023-03-31 | Preprint
DOI: 10.1158/1078-0432.c.6529089
Contributors: Amanda Townsend; Niall Tebbutt; Christos Karapetis; Pamela Cooper; Nimit Singhal; Susan Yeend; Louise Pirc; Rohit Joshi; Jennifer Hardingham; Timothy Price
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Data from Phase IB/II Study of Second-Line Therapy with Panitumumab, Irinotecan, and Everolimus (PIE) in <i>KRAS</i> Wild-Type Metastatic Colorectal Cancer

2023-03-31 | Preprint
DOI: 10.1158/1078-0432.c.6529089.v1
Contributors: Amanda Townsend; Niall Tebbutt; Christos Karapetis; Pamela Cooper; Nimit Singhal; Susan Yeend; Louise Pirc; Rohit Joshi; Jennifer Hardingham; Timothy Price
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Figure S1 from Phase IB/II Study of Second-Line Therapy with Panitumumab, Irinotecan, and Everolimus (PIE) in <i>KRAS</i> Wild-Type Metastatic Colorectal Cancer

2023-03-31 | Preprint
DOI: 10.1158/1078-0432.22475481
Contributors: Amanda Townsend; Niall Tebbutt; Christos Karapetis; Pamela Cooper; Nimit Singhal; Susan Yeend; Louise Pirc; Rohit Joshi; Jennifer Hardingham; Timothy Price
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Figure S1 from Phase IB/II Study of Second-Line Therapy with Panitumumab, Irinotecan, and Everolimus (PIE) in <i>KRAS</i> Wild-Type Metastatic Colorectal Cancer

2023-03-31 | Preprint
DOI: 10.1158/1078-0432.22475481.v1
Contributors: Amanda Townsend; Niall Tebbutt; Christos Karapetis; Pamela Cooper; Nimit Singhal; Susan Yeend; Louise Pirc; Rohit Joshi; Jennifer Hardingham; Timothy Price
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Figure S2 from Phase IB/II Study of Second-Line Therapy with Panitumumab, Irinotecan, and Everolimus (PIE) in <i>KRAS</i> Wild-Type Metastatic Colorectal Cancer

2023-03-31 | Preprint
DOI: 10.1158/1078-0432.22475478
Contributors: Amanda Townsend; Niall Tebbutt; Christos Karapetis; Pamela Cooper; Nimit Singhal; Susan Yeend; Louise Pirc; Rohit Joshi; Jennifer Hardingham; Timothy Price
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Figure S2 from Phase IB/II Study of Second-Line Therapy with Panitumumab, Irinotecan, and Everolimus (PIE) in <i>KRAS</i> Wild-Type Metastatic Colorectal Cancer

2023-03-31 | Preprint
DOI: 10.1158/1078-0432.22475478.v1
Contributors: Amanda Townsend; Niall Tebbutt; Christos Karapetis; Pamela Cooper; Nimit Singhal; Susan Yeend; Louise Pirc; Rohit Joshi; Jennifer Hardingham; Timothy Price
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Immunohistochemistry features and molecular pathology of appendiceal neoplasms

Critical Reviews in Clinical Laboratory Sciences
2021-08-18 | Journal article
DOI: 10.1080/10408363.2021.1881756
Contributors: Reger R. Mikaeel; Joanne P. Young; Gonzalo Tapia Rico; Peter J. Hewett; Jennifer E. Hardingham; Wendy Uylaki; Mehgan Horsnell; Timothy J. Price
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Anti-Cancer Effects of an Optimised Combination of Ginsenoside Rg3 Epimers on Triple Negative Breast Cancer Models

Pharmaceuticals
2021-06-30 | Journal article
DOI: 10.3390/ph14070633
Contributors: Maryam Nakhjavani; Eric Smith; Helen M. Palethorpe; Yoko Tomita; Kenny Yeo; Tim J. Price; Amanda R. Townsend; Jennifer E. Hardingham
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Anti-Angiogenic Properties of Ginsenoside Rg3 Epimers: In Vitro Assessment of Single and Combination Treatments

Cancers
2021-05-06 | Journal article
DOI: 10.3390/cancers13092223
Contributors: Maryam Nakhjavani; Eric Smith; Kenny Yeo; Helen M. Palethorpe; Yoko Tomita; Tim J. Price; Amanda R. Townsend; Jennifer E. Hardingham
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In Vitro Synergistic Inhibition of HT-29 Proliferation and 2H-11 and HUVEC Tubulogenesis by Bacopaside I and II Is Associated with Ca2+ Flux and Loss of Plasma Membrane Integrity

Pharmaceuticals
2021-05-06 | Journal article
DOI: 10.3390/ph14050436
Contributors: Yoko Tomita; Eric Smith; Helen M. Palethorpe; Maryam Nakhjavani; Kenny K. L. Yeo; Amanda R. Townsend; Timothy J. Price; Andrea J. Yool; Jennifer E. Hardingham
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Appendiceal neoplasm incidence and mortality rates are on the rise in Australia

Expert Review of Gastroenterology & Hepatology
2021-02-01 | Journal article
DOI: 10.1080/17474124.2021.1832467
Contributors: Reger R. Mikaeel; Joanne P. Young; Jennifer E. Hardingham; Gonzalo Tapia Rico; Peter J. Hewett; Erin L. Symonds; Suzanne Edwards; Eric Smith; Yoko Tomita; Wendy Uylaki et al.
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High Preoperative Levels of Circulating SFRP5 Predict Better Prognosis in Colorectal Cancer Patients

Future Oncology
2020-11 | Journal article
DOI: 10.2217/fon-2020-0356
Contributors: Chandra Kirana; Eric Smith; Doan T Ngo; Markus I Trochsler; Peter J Hewett; Richard S Stubbs; Jennifer E Hardingham; Guy J Maddern; Ehud Hauben
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Anti-Angiogenic Properties of Ginsenoside Rg3

Molecules
2020-10-23 | Journal article
DOI: 10.3390/molecules25214905
Contributors: Maryam Nakhjavani; Eric Smith; Amanda R. Townsend; Timothy J. Price; Jennifer E. Hardingham
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Druggable Molecular Targets for the Treatment of Triple Negative Breast Cancer

Journal of Breast Cancer
2019 | Journal article
DOI: 10.4048/jbc.2019.22.e39
Contributors: Maryam Nakhjavani; Jennifer E Hardingham; Helen M Palethorpe; Tim J Price; Amanda R Townsend
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Outcomes for Metastatic Colorectal Cancer Based on Microsatellite Instability: Results from the South Australian Metastatic Colorectal Cancer Registry

Targeted Oncology
2019 | Journal article
DOI: 10.1007/s11523-018-0615-9
EID:

2-s2.0-85060185397
Contributors: Chong, L.C.; Townsend, A.R.; Young, J.; Roy, A.; Piantadosi, C.; Hardingham, J.E.; Roder, D.; Karapetis, C.; Padbury, R.; Maddern, G. et al.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

Right or Left Primary Site of Colorectal Cancer: Outcomes From the Molecular Analysis of the AGITG MAX Trial

Clinical Colorectal Cancer
2019 | Journal article
DOI: 10.1016/j.clcc.2018.12.002
EID:

2-s2.0-85060755567
Contributors: Tapia Rico, G.; Price, T.; Tebbutt, N.; Hardingham, J.; Lee, C.; Buizen, L.; Wilson, K.; Gebski, V.; Townsend, A.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

Bacopasides I and II Act in Synergy to Inhibit the Growth, Migration and Invasion of Breast Cancer Cell Lines

Molecules
2019-09-30 | Journal article
DOI: 10.3390/molecules24193539
Contributors: Helen M. Palethorpe; Eric Smith; Yoko Tomita; Maryam Nakhjavani; Andrea J. Yool; Timothy J. Price; Joanne P. Young; Amanda R. Townsend; Jennifer E. Hardingham
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Combined pharmacological administration of AQP1 ion channel blocker AqB011 and water channel blocker Bacopaside II amplifies inhibition of colon cancer cell migration

Scientific Reports
2019-09-02 | Journal article
DOI: 10.1038/s41598-019-49045-9
Contributors: Michael L. De Ieso; Jinxin V. Pei; Saeed Nourmohammadi; Eric Smith; Pak Hin Chow; Mohamad Kourghi; Jennifer E. Hardingham; Andrea J. Yool
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Stereoselective Anti-Cancer Activities of Ginsenoside Rg3 on Triple Negative Breast Cancer Cell Models

Pharmaceuticals
2019-08-01 | Journal article
DOI: 10.3390/ph12030117
Contributors: Maryam Nakhjavani; Helen M. Palethorpe; Yoko Tomita; Eric Smith; Timothy J. Price; Andrea J. Yool; Jinxin V. Pei; Amanda R. Townsend; Jennifer E. Hardingham
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Bumetanide-Derived Aquaporin 1 Inhibitors, AqB013 and AqB050 Inhibit Tube Formation of Endothelial Cells through Induction of Apoptosis and Impaired Migration In Vitro

International Journal of Molecular Sciences
2019-04 | Journal article | Author
DOI: 10.3390/ijms20081818
Contributors: Yoko Tomita; Helen Palethorpe; Eric Smith; Maryam Nakhjavani; Amanda R. Townsend; Timothy J. Price; Andrea Yool; Jennifer Hardingham
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Multidisciplinary Digital Publishing Institute
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Reduced aquaporin-1 transcript expression in colorectal carcinoma is associated with promoter hypermethylation

Epigenetics
2019-02-01 | Journal article
DOI: 10.1080/15592294.2019.1580112
Contributors: Eric Smith; Yoko Tomita; Helen M. Palethorpe; Stuart Howell; Maryam Nakhjavani; Amanda R. Townsend; Timothy J. Price; Joanne P. Young; Jennifer E. Hardingham
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Ginsenoside Rg3: Potential Molecular Targets and Therapeutic Indication in Metastatic Breast Cancer

Medicines
2019-01 | Journal article | Author
DOI: 10.3390/medicines6010017
Contributors: Maryam Nakhjavani; Jennifer Hardingham; Helen M Palethorpe; Yoko Tomita; Eric Smith; Tim J Price; Amanda R Townsend
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Multidisciplinary Digital Publishing Institute
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The prognostic impact of consensus molecular subtypes (CMS) and its predictive effects for bevacizumab benefit in metastatic colorectal cancer: molecular analysis of the AGITG MAX clinical trial

Annals of oncology : official journal of the European Society for Medical Oncology
2018 | Journal article
DOI: 10.1093/annonc/mdy410
EID:

2-s2.0-85058589953
Contributors: Mooi, J.K.; Wirapati, P.; Asher, R.; Lee, C.K.; Savas, P.; Price, T.J.; Townsend, A.; Hardingham, J.; Buchanan, D.; Williams, D. et al.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

Phase IB/II Study of Second-Line Therapy with Panitumumab, Irinotecan, and Everolimus (PIE) in KRAS Wild-Type Metastatic Colorectal Cancer

Clinical Cancer Research
2018-08-15 | Journal article
DOI: 10.1158/1078-0432.CCR-17-3590
Contributors: Amanda Townsend; Niall Tebbutt; Christos Karapetis; Pamela Cooper; Nimit Singhal; Susan Yeend; Louise Pirc; Rohit Joshi; Jennifer Hardingham; Timothy Price
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The Purified Extract from the Medicinal Plant <i>Bacopa monnieri</i>, Bacopaside II, Inhibits Growth of Colon Cancer Cells In Vitro by Inducing Cell Cycle Arrest and Apoptosis

Cells
2018-07 | Journal article
DOI: 10.3390/cells7070081
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Multidisciplinary Digital Publishing Institute
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The Aquaporin 1 Inhibitor Bacopaside II Reduces Endothelial Cell Migration and Tubulogenesis and Induces Apoptosis

International Journal of Molecular Sciences
2018-02 | Journal article
DOI: 10.3390/ijms19030653
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Biology and therapeutic implications of VEGF-A splice isoforms and single-nucleotide polymorphisms in colorectal cancer

International Journal of Cancer
2017 | Journal article
DOI: 10.1002/ijc.30567
EID:

2-s2.0-85011632816
Contributors: Canavese, M.; Ngo, D.T.M.; Maddern, G.J.; Hardingham, J.E.; Price, T.J.; Hauben, E.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

Findings in young adults at colonoscopy from a hospital service database audit

BMC Gastroenterology
2017 | Journal article
DOI: 10.1186/s12876-017-0612-y
EID:

2-s2.0-85018465465
Contributors: Wong, S.; Lidums, I.; Rosty, C.; Ruszkiewicz, A.; Parry, S.; Win, A.K.; Tomita, Y.; Vatandoust, S.; Townsend, A.; Patel, D. et al.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

Soluble HLA-G is a differential prognostic marker in sequential colorectal cancer disease stages

International Journal of Cancer
2017 | Journal article
DOI: 10.1002/ijc.30667
EID:

2-s2.0-85016425278
Contributors: Kirana, C.; Ruszkiewicz, A.; Stubbs, R.S.; Hardingham, J.E.; Hewett, P.J.; Maddern, G.J.; Hauben, E.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

High early growth response 1 (EGR1) expression correlates with resistance to anti-EGFR treatment in vitro and with poorer outcome in metastatic colorectal cancer patients treated with cetuximab

Clinical and Translational Oncology
2017-06-22 | Journal article
DOI: 10.1007/s12094-016-1596-8
Contributors: S. S. Kumar; Y. Tomita; J. Wrin; M. Bruhn; A. Swalling; M. Mohammed; T. J. Price; J. E. Hardingham
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Role of Aquaporin 1 Signalling in Cancer Development and Progression

International Journal of Molecular Sciences
2017-01 | Journal article
DOI: 10.3390/ijms18020299
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Multidisciplinary Digital Publishing Institute
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Differential inhibition of water and ion channel activities of mammalian aquaporin-1 by two structurally related bacopaside compounds derived from the medicinal plant bacopa monnieri

Molecular Pharmacology
2016 | Journal article
DOI: 10.1124/mol.116.105882
EID:

2-s2.0-84987879927
Contributors: Pei, J.V.; Kourghi, M.; De Ieso, M.L.; Campbell, E.M.; Dorward, H.S.; Hardingham, J.E.; Yool, A.J.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

Pharmacological blockade of aquaporin-1 water channel by AqB013 restricts migration and invasiveness of colon cancer cells and prevents endothelial tube formation in vitro

Journal of Experimental and Clinical Cancer Research
2016 | Journal article
DOI: 10.1186/s13046-016-0310-6
EID:

2-s2.0-84959212627
Contributors: Dorward, H.S.; Du, A.; Bruhn, M.A.; Wrin, J.; Pei, J.V.; Evdokiou, A.; Price, T.J.; Yool, A.J.; Hardingham, J.E.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

Correlation of extended RAS and PIK3CA gene mutation status with outcomes from the phase III AGITG MAX STUDY involving capecitabine alone or in combination with bevacizumab plus or minus mitomycin C in advanced colorectal cancer

British Journal of Cancer
2015 | Journal article
DOI: 10.1038/bjc.2015.37
EID:

2-s2.0-84925340214
Contributors: Price, T.J.; Bruhn, M.A.; Lee, C.K.; Hardingham, J.E.; Townsend, A.R.; Mann, K.P.; Simes, J.; Weickhardt, A.; Wrin, J.W.; Wilson, K. et al.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

Detection and clinical significance of circulating tumor cells in colorectal cancer—20 years of progress

Molecular Medicine
2015 | Journal article
DOI: 10.2119/molmed.2015.00149
EID:

2-s2.0-84945948733
Contributors: Hardingham, J.E.; Grover, P.; Winter, M.; Hewett, P.J.; Price, T.J.; Thierry, B.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

Rising incidence of early-onset colorectal cancer in Australia over two decades: Report and review

Journal of Gastroenterology and Hepatology (Australia)
2015 | Journal article
DOI: 10.1111/jgh.12792
EID:

2-s2.0-84919623529
Contributors: Young, J.P.; Win, A.K.; Rosty, C.; Flight, I.; Roder, D.; Young, G.P.; Frank, O.; Suthers, G.K.; Hewett, P.J.; Ruszkiewicz, A. et al.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

Can we accurately report PTEN status in advanced colorectal cancer?

BMC Cancer
2014 | Journal article
DOI: 10.1186/1471-2407-14-128
EID:

2-s2.0-84896736808
Contributors: Hocking, C.; Hardingham, J.E.; Broadbridge, V.; Wrin, J.; Townsend, A.R.; Tebbutt, N.; Cooper, J.; Ruszkiewicz, A.; Lee, C.; Price, T.J.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

Circulating tumour cells: The evolving concept and the inadequacy of their enrichment by EpCAM-based methodology for basic and clinical cancer research

Annals of Oncology
2014 | Journal article
DOI: 10.1093/annonc/mdu018
EID:

2-s2.0-84905174495
Contributors: Grover, P.K.; Cummins, A.G.; Price, T.J.; Roberts-Thomson, I.C.; Hardingham, J.E.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

KRAS G13D mutation and sensitivity to cetuximab or panitumumab in a colorectal cancer cell line model

Gastrointestinal Cancer Research
2014 | Journal article
EID:

2-s2.0-84894592709
Contributors: Sree Kumar, S.; Price, T.J.; Mohyieldin, O.; Borg, M.; Townsend, A.; Hardingham, J.E.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

Nanostructured polystyrene well plates allow unbiased high-throughput characterization of circulating tumor cells

ACS Applied Materials and Interfaces
2014 | Journal article
DOI: 10.1021/am505201s
EID:

2-s2.0-84917706893
Contributors: Wan, Y.; Winter, M.; Delalat, B.; Hardingham, J.E.; Grover, P.K.; Wrin, J.; Voelcker, N.H.; Price, T.J.; Thierry, B.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

Proangiogenic tumor proteins as potential predictive or prognostic biomarkers for bevacizumab therapy in metastatic colorectal cancer

International Journal of Cancer
2014 | Journal article
DOI: 10.1002/ijc.28698
EID:

2-s2.0-84901057832
Contributors: Bruhn, M.A.; Townsend, A.R.; Khoon Lee, C.; Shivasami, A.; Price, T.J.; Wrin, J.; Arentz, G.; Tebbutt, N.C.; Hocking, C.; Cunningham, D. et al.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

ROS1 and ALK fusions in colorectal cancer, with evidence of intratumoral heterogeneity for molecular drivers

Molecular Cancer Research
2014 | Journal article
DOI: 10.1158/1541-7786.MCR-13-0479-T
EID:

2-s2.0-84893116875
Contributors: Aisner, D.L.; Nguyen, T.T.; Paskulin, D.D.; Le, A.T.; Haney, J.; Schulte, N.; Chionh, F.; Hardingham, J.; Mariadason, J.; Tebbutt, N. et al.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

A simple, cost-effective and flexible method for processing of snap-frozen tissue to prepare large amounts of intact RNA using laser microdissection

Biochimie
2012 | Journal article
DOI: 10.1016/j.biochi.2012.06.031
EID:

2-s2.0-84868209251
Contributors: Grover, P.K.; Cummins, A.G.; Price, T.J.; Roberts-Thomson, I.C.; Hardingham, J.E.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

Desmin expression in colorectal cancer stroma correlates with advanced stage disease and marks angiogenic microvessels

Clinical Proteomics
2011 | Journal article
DOI: 10.1186/1559-0275-8-16
EID:

2-s2.0-84860870241
Contributors: Arentz, G.; Chataway, T.; Price, T.J.; Izwan, Z.; Hardi, G.; Cummins, A.G.; Hardingham, J.E.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

Impact of KRAS and BRAF gene mutation status on outcomes from the phase III AGITG MAX trial of capecitabine alone or in combination with bevacizumab and mitomycin in advanced colorectal cancer

Journal of Clinical Oncology
2011 | Journal article
DOI: 10.1200/JCO.2010.34.5520
EID:

2-s2.0-79960149283
Contributors: Price, T.J.; Hardingham, J.E.; Lee, C.K.; Weickhardt, A.; Townsend, A.R.; Wrin, J.W.; Chua, A.; Shivasami, A.; Cummins, M.M.; Murone, C. et al.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

Small Cell Lung Cancer: Patterns of care and their influence on survival - 25years experience of a single Australian oncology unit

Asia-Pacific Journal of Clinical Oncology
2011 | Journal article
DOI: 10.1111/j.1743-7563.2011.01426.x
EID:

2-s2.0-80052227813
Contributors: Bishnoi, S.; Pittman, K.; Colbeck, M.; Townsend, A.; Hardingham, J.; Sukumaran, S.; Hooper, B.; Tuck, M.; Roder, D.; Luke, C. et al.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

Length of lymphangiogenesis in the rectal tissues distal to rectal cancer

Tumor Biology
2010 | Journal article
DOI: 10.1007/s13277-010-0084-y
EID:

2-s2.0-78449253600
Contributors: Li, L.-R.; Fang, Y.-J.; Pan, Z.-Z.; Wu, X.-J.; Wan, D.-S.; Hardingham, J.E.; Rieger, N.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

Stem cell marker olfactomedin 4: Critical appraisal of its characteristics and role in tumorigenesis

Cancer and Metastasis Reviews
2010 | Journal article
DOI: 10.1007/s10555-010-9262-z
EID:

2-s2.0-79952202070
Contributors: Grover, P.K.; Hardingham, J.E.; Cummins, A.G.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier

Extent of over-expression of hepatocyte growth factor receptor in colorectal tumours is dependent on the choice of normaliser

Biochemical and Biophysical Research Communications
2006 | Journal article
DOI: 10.1016/j.bbrc.2006.01.060
EID:

2-s2.0-32344451368
Contributors: Laidlaw, A.M.; Copeland, B.; Ross, C.M.; Hardingham, J.E.
Source: Self-asserted source
Jennifer Hardingham via Scopus - Elsevier
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Peer review (2 reviews for 1 publication/grant)

Review activity for BMC gastroenterology (2)
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