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Employment (3)

The Francis Crick Institute: London, GB

2019-08-20 to present | SENIOR LABORATORY RESEARCH SCIENTIST (Protein Biogenesis)
Employment
Source: Self-asserted source
Aleksandra Pajak

Karolinska Institute: Stockholm, SE

2014-01-26 to 2018-09-30 | PostDoc (Medical Biochemistry & Biophysics)
Employment
Source: Self-asserted source
Aleksandra Pajak

Okayama University: Okayama, Okayama, JP

2013-03-01 to 2013-09-01 | PostDoc (Natural Science and Technology)
Employment
Source: Self-asserted source
Aleksandra Pajak

Education and qualifications (2)

Newcastle University: Newcastle upon Tyne, Tyne and Wear, GB

2009-09-01 to 2013-02-14 | PhD (Neurosience, Wellcome Trust Center for Mitochondria Research)
Education
Source: Self-asserted source
Aleksandra Pajak

Newcastle University: Newcastle upon Tyne, Tyne and Wear, GB

2008-10-01 to 2009-09-01 | MRes in Medical and Molecular Biosciences (Neurosience)
Education
Source: Self-asserted source
Aleksandra Pajak

Works (10)

Defects of mitochondrial RNA turnover lead to the accumulation of double-stranded RNA in vivo

PLOS Genetics
2019-07-31 | Journal article
DOI: 10.1371/journal.pgen.1008240
Contributors: Aleksandra Pajak; Aleksandra Trifunovic; Isabelle Laine; Paula Clemente; Najla El-Fissi; Florian A. Schober; Camilla Maffezzini; Javier Calvo-Garrido; Rolf Wibom; Roberta Filograna et al.
Source: check_circle
Crossref

Modulation of mtDNA copy number ameliorates the pathological consequences of a heteroplasmic mtDNA mutation in the mouse

Science Advances
2019-04-05 | Journal article
DOI: 10.1126/sciadv.aav9824
Contributors: R. Filograna; C. Koolmeister; M. Upadhyay; A. Pajak; P. Clemente; R. Wibom; M. L. Simard; A. Wredenberg; C. Freyer; J. B. Stewart et al.
Source: check_circle
Crossref

Chorea, psychosis, acanthocytosis, and prolonged survival associated with ELAC2 mutations.

Neurology
2018-09 | Journal article
DOI: 10.1212/WNL.0000000000006320
PMID: 30217939
PMC: PMC6177277
Contributors: Paucar M; Pajak A; Freyer C; Bergendal Å; Döry M; Laffita-Mesa JM; Stranneheim H; Lagerstedt-Robinson K; Savitcheva I; Walker RH et al.
Source: Self-asserted source
Aleksandra Pajak via Europe PubMed Central

Adult Onset Leigh Syndrome in the Intensive Care Setting: A Novel Presentation of a C12orf65 Related Mitochondrial Disease.

Journal of neuromuscular diseases
2015-10 | Journal article
DOI: 10.3233/jnd-150121
PMID: 27858754
PMC: PMC5240610
Contributors: Wesolowska M; Gorman GS; Alston CL; Pajak A; Pyle A; He L; Griffin H; Chinnery PF; Miller JA; Schaefer AM et al.
Source: Self-asserted source
Aleksandra Pajak via Europe PubMed Central

Intra-mitochondrial Methylation Deficiency Due to Mutations in SLC25A26.

American journal of human genetics
2015-10 | Journal article
DOI: 10.1016/j.ajhg.2015.09.013
PMID: 26522469
PMC: PMC4667130
Contributors: Kishita Y; Pajak A; Bolar NA; Marobbio CM; Maffezzini C; Miniero DV; Monné M; Kohda M; Stranneheim H; Murayama K et al.
Source: Self-asserted source
Aleksandra Pajak via Europe PubMed Central

SUV3 helicase is required for correct processing of mitochondrial transcripts.

Nucleic acids research
2015-07 | Journal article
DOI: 10.1093/nar/gkv692
PMID: 26152302
PMC: PMC4551930
Contributors: Clemente P; Pajak A; Laine I; Wibom R; Wedell A; Freyer C; Wredenberg A
Source: Self-asserted source
Aleksandra Pajak via Europe PubMed Central

C7orf30 specifically associates with the large subunit of the mitochondrial ribosome and is involved in translation.

Nucleic acids research
2012-01 | Journal article
DOI: 10.1093/nar/gkr1271
PMID: 22238375
PMC: PMC3351149
Contributors: Wanschers BF; Szklarczyk R; Pajak A; van den Brand MA; Gloerich J; Rodenburg RJ; Lightowlers RN; Nijtmans LG; Huynen MA
Source: Self-asserted source
Aleksandra Pajak via Europe PubMed Central

Termination of protein synthesis in mammalian mitochondria.

The Journal of biological chemistry
2011-08 | Journal article
DOI: 10.1074/jbc.r111.290585
PMID: 21873426
PMC: PMC3186377
Contributors: Chrzanowska-Lightowlers ZM; Pajak A; Lightowlers RN
Source: Self-asserted source
Aleksandra Pajak via Europe PubMed Central

Translation termination in human mitochondrial ribosomes.

Biochemical Society transactions
2010-12 | Journal article
DOI: 10.1042/bst0381523
PMID: 21118119
Contributors: Richter R; Pajak A; Dennerlein S; Rozanska A; Lightowlers RN; Chrzanowska-Lightowlers ZM
Source: Self-asserted source
Aleksandra Pajak via Europe PubMed Central

A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome.

The EMBO journal
2010-02 | Journal article
DOI: 10.1038/emboj.2010.14
PMID: 20186120
PMC: PMC2845271
Contributors: Richter R; Rorbach J; Pajak A; Smith PM; Wessels HJ; Huynen MA; Smeitink JA; Lightowlers RN; Chrzanowska-Lightowlers ZM
Source: Self-asserted source
Aleksandra Pajak via Europe PubMed Central
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