Personal information

United States

Activities

Employment (2)

Wyss Institute: Boston, US

2023 to present | Scientist II
Employment
Source: Self-asserted source
Megan Sperry

Harvard University Wyss Institute for Biologically Inspired Engineering: Boston, MA, US

2019 to 2023 | Postdoctoral Fellow
Employment
Source: Self-asserted source
Megan Sperry

Education and qualifications (3)

University of Pennsylvia: Philadelphia, Pennsylvania, US

2013 to 2019 | PhD (Bioengineering)
Education
Source: Self-asserted source
Megan Sperry

Imperial College London: London, GB

2012 to 2014 | MPhil (Structural Biomechanics)
Education
Source: Self-asserted source
Megan Sperry

Boston University: Boston, Massachusetts, US

2008 to 2012 | BS (Biomedical Engineering)
Education
Source: Self-asserted source
Megan Sperry

Works (25)

Inflammatory Bowel Disease Drivers Revealed in Human Organ Chips

2024-12-08 | Preprint
Contributors: Alican Özkan; Gwenn Merry; David B. Chou; Ryan R. Posey; Anna Stejskalova; Karina Calderon; Megan Sperry; Viktor Horvath; Lorenzo E. Ferri; Emanuela Carlotti et al.
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Crossref

Identification of pharmacological inducers of a reversible hypometabolic state for whole organ preservation

eLife
2024-09-24 | Journal article
Contributors: Megan M Sperry; Berenice Charrez; Haleh Fotowat; Erica Gardner; Kanoelani Pilobello; Zohreh Izadifar; Tiffany Lin; Abigail Kuelker; Sahith Kaki; Michael Lewandowski et al.
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Crossref

Identification of pharmacological inducers of a reversible hypometabolic state for whole organ preservation

eLife
2024-09-24 | Journal article
Contributors: Megan M Sperry; Berenice Charrez; Haleh Fotowat; Erica Gardner; Kanoelani Pilobello; Zohreh Izadifar; Tiffany Lin; Abigail Kuelker; Sahith Kaki; Michael Lewandowski et al.
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Crossref

Identification of pharmacological inducers of a reversible hypometabolic state for whole organ preservation

2024-08-08 | Preprint
Contributors: Megan M Sperry; Berenice Charrez; Haleh Fotowat; Erica Gardner; Kanoelani Pilobello; Zohreh Izadifar; Tiffany Lin; Abigail Kuelker; Sahith Kaki; Michael Lewandowski et al.
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Crossref

Identification of pharmacological inducers of a reversible hypometabolic state for whole organ preservation

2024-02-06 | Preprint
Contributors: Megan M. Sperry; Berenice Charrez; Haleh Fotowat; Erica Gardner; Kanoelani Pilobello; Zohreh Izadifar; Tiffany Lin; Abigail Kuelker; Sahith Kaki; Michael Lewandowski et al.
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Crossref

Embryos assist morphogenesis of others through calcium and ATP signaling mechanisms in collective teratogen resistance

Nature Communications
2024-01-17 | Journal article
Contributors: Angela Tung; Megan M. Sperry; Wesley Clawson; Ananya Pavuluri; Sydney Bulatao; Michelle Yue; Ramses Martinez Flores; Vaibhav P. Pai; Patrick McMillen; Franz Kuchling et al.
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Crossref

Target-agnostic drug prediction integrated with medical record analysis uncovers differential associations of statins with increased survival in COVID-19 patients

PLOS Computational Biology
2023-05-05 | Journal article
Contributors: Megan M. Sperry; Teresa M. Przytycka; Tomiko T. Oskotsky; Ivana Marić; Shruti Kaushal; Takako Takeda; Viktor Horvath; Rani K. Powers; Melissa Rodas; Brooke Furlong et al.
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Crossref

Identification of pharmacological inducers of a reversible hypometabolic state for whole organ preservation

2023-02-28 | Preprint
Contributors: Megan M. Sperry; Berenice Charrez; Haleh Fotowat; Erica Gardner; Kanoelani Pilobello; Zohreh Izadifar; Tiffany Lin; Abigail Kuelker; Sahith Kaki; Michael Lewandowski et al.
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Crossref

Enhancers of Host Immune Tolerance to Bacterial Infection Discovered Using Linked Computational and Experimental Approaches

Advanced Science
2022-09 | Journal article
Contributors: Megan M. Sperry; Richard Novak; Vishal Keshari; Alexandre L. M. Dinis; Mark J. Cartwright; Diogo M. Camacho; Jean‐François Paré; Michael Super; Michael Levin; Donald E. Ingber
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Crossref

Target-agnostic drug prediction integrated with medical record analysis uncovers differential associations of statins with increased survival in COVID-19 patients

2022-04-13 | Preprint
Contributors: Megan M. Sperry; Tomiko Oskotsky; Ivana Marić; Shruti Kaushal; Takako Takeda; Viktor Horvath; Rani K. Powers; Melissa Rodas; Brooke Furlong; Mercy Soong et al.
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Crossref

Target-agnostic discovery of Rett Syndrome therapeutics by coupling computational network analysis and CRISPR-enabled in vivo disease modeling

2022-03-21 | Preprint
Contributors: R. Novak; T. Lin; S. Kaushal; M. Sperry; F. Vigneault; E. Gardner; S. Loomba; K. Shcherbina; V. Keshari; A. Dinis et al.
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Crossref

Painful temporomandibular joint overloading induces structural remodeling in the pericellular matrix of that joint's chondrocytes

Journal of Orthopaedic Research
2022-02 | Journal article
Contributors: Melissa Franklin; Megan M. Sperry; Evan Phillips; Eric J. Granquist; Michele Marcolongo; Beth A. Winkelstein
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Crossref

Acute multidrug delivery via a wearable bioreactor facilitates long-term limb regeneration and functional recovery in adult Xenopus laevis

Science Advances
2022-01-28 | Journal article
Contributors: Nirosha J. Murugan; Hannah J. Vigran; Kelsie A. Miller; Annie Golding; Quang L. Pham; Megan M. Sperry; Cody Rasmussen-Ivey; Anna W. Kane; David L. Kaplan; Michael Levin
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Crossref

Enhancers of host immune tolerance to bacterial infection discovered using linked computational and experimental approaches

2021-10-01 | Other
Contributors: Megan M. Sperry; Richard Novak; Vishal Keshari; Alexandre L. M. Dinis; Mark J. Cartwright; Diogo M. Camacho; Jean-François Paré; Mike Super; Michael Levin; Donald E. Ingber
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Crossref

Early changes in brain network topology and activation of affective pathways predict persistent pain in the rat.

Pain
2020-08 | Journal article
Contributors: Sperry MM; Granquist EJ; Winkelstein BA
Source: Self-asserted source
Megan Sperry via Europe PubMed Central

Intra‐articular etanercept attenuates pain and hypoxia from TMJ loading in the rat

Journal of Orthopaedic Research
2020-06 | Journal article
Contributors: Megan M. Sperry; Ya‐Hsin Yu; Sonia Kartha; Prabesh Ghimire; Rachel L. Welch; Beth A. Winkelstein; Eric J. Granquist
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Crossref

Experimental Methods to Inform Diagnostic Approaches for Painful TMJ Osteoarthritis

Journal of Dental Research
2019 | Journal article
EID:

2-s2.0-85062567791

Contributors: Sperry, M.M.; Kartha, S.; Winkelstein, B.A.; Granquist, E.J.
Source: Self-asserted source
Megan Sperry via Scopus - Elsevier

Lower back pain and healthy subjects exhibit distinct lower limb perturbation response strategies: A preliminary study

Journal of Back and Musculoskeletal Rehabilitation
2019 | Journal article
EID:

2-s2.0-85060979378

Contributors: Sperry, M.M.; Phillips, A.T.M.; Mcgregor, A.H.
Source: Self-asserted source
Megan Sperry via Scopus - Elsevier

Response to the Letter to the Editor: “Intra-articular Injection of Mono-iodoacetate and TMJ Osteoarthritis”

Journal of Dental Research
2019 | Journal article
EID:

2-s2.0-85067873947

Contributors: Sperry, M.M.; Kartha, S.; Winkelstein, B.A.; Granquist, E.J.
Source: Self-asserted source
Megan Sperry via Scopus - Elsevier

Grading facial expression is a sensitive means to detect grimace differences in orofacial pain in a rat model

Scientific Reports
2018 | Journal article
EID:

2-s2.0-85060915193

Contributors: Sperry, M.M.; Yu, Y.-H.; Welch, R.L.; Granquist, E.J.; Winkelstein, B.A.
Source: Self-asserted source
Megan Sperry via Scopus - Elsevier

Inter-subject FDG PET Brain Networks Exhibit Multi-scale Community Structure with Different Normalization Techniques

Annals of Biomedical Engineering
2018 | Journal article
EID:

2-s2.0-85047954412

Contributors: Sperry, M.M.; Kartha, S.; Granquist, E.J.; Winkelstein, B.A.
Source: Self-asserted source
Megan Sperry via Scopus - Elsevier

Mapping of pain circuitry in early post-natal development using manganese-enhanced MRI in rats

Neuroscience
2017 | Journal article
EID:

2-s2.0-85018470998

Contributors: Sperry, M.M.; Kandel, B.M.; Wehrli, S.; Bass, K.N.; Das, S.R.; Dhillon, P.S.; Gee, J.C.; Barr, G.A.
Source: Self-asserted source
Megan Sperry via Scopus - Elsevier

Rentian scaling for the measurement of optimal embedding of complex networks into physical space

Journal of Complex Networks
2017 | Journal article
EID:

2-s2.0-85023192851

Contributors: Sperry, M.M.; Telesford, Q.K.; Klimm, F.; Bassett, D.S.
Source: Self-asserted source
Megan Sperry via Scopus - Elsevier

The Interface of Mechanics and Nociception in Joint Pathophysiology: Insights from the Facet and Temporomandibular Joints

Journal of Biomechanical Engineering
2017 | Journal article
EID:

2-s2.0-85009985641

Contributors: Sperry, M.M.; Ita, M.E.; Kartha, S.; Zhang, S.; Yu, Y.-H.; Winkelstein, B.
Source: Self-asserted source
Megan Sperry via Scopus - Elsevier

Characterization of the poroelastic material properties of skeletal repair tissues using microindentation

ASME 2011 Summer Bioengineering Conference, SBC 2011
2011 | Conference paper
EID:

2-s2.0-84881250204

Contributors: Sperry, M.M.; Hayward, L.N.M.; Miller, G.J.; Morgan, E.F.
Source: Self-asserted source
Megan Sperry via Scopus - Elsevier

Peer review (1 review for 1 publication/grant)

Review activity for Nature reviews. (1)