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ResearcherID: A-4233-2009

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Employment (1)

Instituto Butantan: São Paulo, São Paulo, BR

1987-02-18 to present | Pesquisador Científico (Laboratório de Fisiopatologia)
Employment
Source: Self-asserted source
Luis Goncalves

Education and qualifications (1)

Instituto Butantan: São Paulo, São Paulo, BR

(Laboratório de Fisiopatologia)
Education
Source: Self-asserted source
Luis Goncalves

Works (42)

Effects of Mauritia flexuosa L. f. buriti oil on symptoms induced by Bothrops moojeni snake envenomation

Journal of Ethnopharmacology
2023-09 | Journal article
DOI: 10.1016/j.jep.2023.116612
Part of ISSN: 0378-8741
Contributors: Patrícia Siqueira de Melo Rodrigues; Hemilly Martins; Milena Santos Falcão; Márcio Trevisan; Fernanda Calheta Vieira Portaro; Lais Gomes da Silva ; Ida Sigueko Sano-Martins; Luís Roberto de Camargo Gonçalves; Carla Seibert
Source: Self-asserted source
Luis Goncalves

Design, in silico and pharmacological evaluation of a peptide inhibitor of BACE-1

Frontiers in Pharmacology
2023-06-16 | Journal article
DOI: 10.3389/fphar.2023.1184006
Part of ISSN: 1663-9812
Contributors: Renata Boldin; Bianca Cestari Zychar; Luis Roberto C. Gonçalves; Juliana Mozer Sciani
Source: Self-asserted source
Luis Goncalves

Biological characterization of bristle extract of Lonomia descimoni caterpillar (Lepidoptera, Saturniidae) and effectiveness of Lonomia antivenom to neutralize experimental envenomation in rats

Toxicon
2023-02 | Journal article
DOI: 10.1016/j.toxicon.2022.107004
Part of ISSN: 0041-0101
Contributors: Isabelle Valle dos Anjos; Camila Gonzalez; Juana Diaz; Juliana Mozer Sciani; Ida S. Sano-Martins; Luís Roberto C. Gonçalves
Source: Self-asserted source
Luis Goncalves

Formyl peptide receptors are involved in CTX-induced impairment of lymphocyte functions

Toxicon
2023-01 | Journal article
DOI: 10.1016/j.toxicon.2022.106986
Part of ISSN: 0041-0101
Contributors: Vanessa Zambelli; Natália Gabriele Hösch; Sarah Farom; Bianca C. Zychar; Diva D. Spadacci-Morena; Luciana Vieira Carvalho; Rui Curi; Lucilia B. Lepsch; Cristoforo Scavone; Osvaldo Augusto Sant’Anna et al.
Source: Self-asserted source
Luis Goncalves

Modulation of Adhesion Molecules Expression by Different Metalloproteases Isolated from Bothrops Snakes

Toxins
2021-11-15 | Journal article
DOI: 10.3390/toxins13110803
Contributors: Bianca C. Zychar; Patrícia B. Clissa; Eneas Carvalho; Adilson S. Alves; Cristiani Baldo; Eliana L. Faquim-Mauro; Luís Roberto C. Gonçalves
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Synergistic effect of serine protease inhibitors and a bothropic antivenom in reducing local hemorrhage and coagulopathy caused by Bothrops jararaca venom

Toxicon
2021-08 | Journal article
DOI: 10.1016/j.toxicon.2021.06.009
Part of ISSN: 0041-0101
Source: Self-asserted source
Luis Goncalves

Leukocyte recruitment induced by snake venom metalloproteinases: Role of the catalytic domain

Biochemical and Biophysical Research Communications
2020-01 | Journal article
DOI: 10.1016/j.bbrc.2019.10.144
Contributors: Bianca Cestari Zychar; Patrícia Bianca Clissa; Eneas Carvalho; Cristiani Baldo; Luis Roberto C. Gonçalves
Source: check_circle
Crossref

Elevated plasma levels of hepatocyte growth factor in rats experimentally envenomated with Bothrops jararaca venom: Role of snake venom metalloproteases

Toxicon
2019-04 | Journal article
DOI: 10.1016/j.toxicon.2019.03.003
Contributors: B.C. Prezoto; E.E. Kato; L.R.C. Gonçalves; S.C. Sampaio; I.S. Sano-Martins
Source: check_circle
Crossref

Effectiveness of Lonomia antivenom in recovery from the coagulopathy induced by Lonomia orientoandensis and Lonomia casanarensis caterpillars in rats

PLOS Neglected Tropical Diseases
2018-08-16 | Journal article
DOI: 10.1371/journal.pntd.0006721
Contributors: Ida S. Sano-Martins; Jean-Philippe Chippaux; Camila González; Isabelle Valle Anjos; Juana Díaz; Luis Roberto C. Gonçalves
Source: check_circle
Crossref

Edema and Nociception Induced by Philodryas patagoniensis Venom in Mice: A Pharmacological Evaluation with Implications for the Accident Treatment

Journal of Pharmacology and Experimental Therapeutics
2017 | Journal article
DOI: 10.1124/jpet.116.239640
WOSUID:

WOS:000401897700002
Contributors: Lopes, Priscila Hess; Rocha, Marisa M. T.; Kuniyoshi, Alexandre Kazuo; Vieira Portaro, Fernanda Calheta; Goncalves, Luis Roberto C.
Source: Self-asserted source
Luis Goncalves via ResearcherID

Experimental Bothrops atrox envenomation: Efficacy of antivenom therapy and the combination of Bothrops antivenom with dexamethasone

Plos Neglected Tropical Diseases
2017 | Journal article
DOI: 10.1371/journal.pntd.0005458
WOSUID:

WOS:000402251300048
Contributors: Barreto, Gnls; de Oliveira, S. S.; dos Anjos, I. V.; Chalkidis, H. D.; Mourao, R. H. V.; Moura-da-Silva, A. M.; Sano-Martins, I. S.; Goncalves, L. R. D.
Source: Self-asserted source
Luis Goncalves via ResearcherID

Preliminary molecular characterization of a proinflammatory and nociceptive molecule from the Echinometra lucunter spines extracts

Journal of Venomous Animals and Toxins Including Tropical Diseases
2017 | Journal article
DOI: 10.1186/s40409-017-0133-8
WOSUID:

WOS:000412195600001
Contributors: Sciani, Juliana Mozer; Zychar, Bianca; Goncalves, Luis Roberto; Giorgi, Renata; Nogueira, Thiago; Pimenta, Daniel Carvalho
Source: Self-asserted source
Luis Goncalves via ResearcherID

Echinometrin: A novel mast cell degranulating peptide from the coelomic liquid of Echinometra lucunter sea urchin

Peptides
2014 | Journal article
DOI: 10.1016/j.peptides.2013.07.031
WOSUID:

WOS:000334507700003
Contributors: Sciani, Juliana Mozer; Sampaio, Marlos Cortez; Zychar, Bianca Cestari; de Camargo Goncalves, Luis Roberto; Giorgi, Renata; Nogueira, Thiago de Oliveira; de Melo, Robson Lopes; Pereira Teixeira, Catarina de Fatima; Pimenta, Daniel Carvalho
Source: Self-asserted source
Luis Goncalves via ResearcherID

Inhibitory effect of Crotalus durissus terrificus venom on chronic edema induced by injection of bacillus Calmette-Guerin into the footpad of mice

Toxicon
2013 | Journal article
DOI: 10.1016/j.toxicon.2012.12.003
WOSUID:

WOS:000315239300012
Contributors: da Silva, Nancy Gimenes; Sampaio, Sandra Coccuzzo; Goncalves, Luis Roberto C.
Source: Self-asserted source
Luis Goncalves via ResearcherID
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Inflammatory effects of patagonfibrase, a metalloproteinase from Philodryas patagoniensis (Patagonia Green Racer; Dipsadidae) venom

Experimental Biology and Medicine
2011 | Journal article
DOI: 10.1258/ebm.2011.011125
WOSUID:

WOS:000296106900009
Contributors: Elisa Peichoto, Maria; Zychar, Bianca Cestari; Luiz Tavares, Flavio; Goncalves, Luis Roberto Camargo; Acosta, Ofelia; Santoro, Marcelo Larami
Source: Self-asserted source
Luis Goncalves via ResearcherID

Involvement of circulating platelets on the hyperalgesic response evoked by carrageenan and Bothrops jararaca snake venom

Journal of Thrombosis and Haemostasis
2011 | Journal article
DOI: 10.1111/j.1538-7836.2011.04449.x
WOSUID:

WOS:000295382900022
Contributors: Yamashita, K. M.; Nogueira, T. O.; Senise, L. V.; Cirillo, M. C.; Goncalves, L. R. C.; Sano-Martins, I. S.; Giorgi, R.; Santoro, M. L.
Source: Self-asserted source
Luis Goncalves via ResearcherID

Pro-inflammatory effects of the aqueous extract of Echinometra lucunter sea urchin spines

Experimental Biology and Medicine
2011 | Journal article
DOI: 10.1258/ebm.2010.010257
WOSUID:

WOS:000295201200004
Contributors: Sciani, Juliana Mozer; Zychar, Bianca Cestari; Goncalves, Luis Roberto Camargo; Nogueira, Thiago de Oliveira; Giorgi, Renata; Pimenta, Daniel Carvalho
Source: Self-asserted source
Luis Goncalves via ResearcherID

Contribution of metalloproteases, serine proteases and phospholipases A(2) to the inflammatory reaction induced by Bothrops jararaca crude venom in mice

Toxicon
2010 | Journal article
DOI: 10.1016/j.toxicon.2009.07.025
WOSUID:

WOS:000274579100008
Contributors: Zychar, Bianca Cestari; Dale, Camila Squazoni; Demarchi, Denise Soares; Goncalves, Luis Roberto C.
Source: Self-asserted source
Luis Goncalves via ResearcherID

Crotoxin is responsible for the long-lasting anti-inflammatory effect of Crotalus durissus terrificus snake venom: involvement of formyl peptide receptors

Toxicon
2010 | Journal article
DOI: 10.1016/j.toxicon.2009.12.011
WOSUID:

WOS:000276436600006
Contributors: Nunes, F. P. B.; Zychar, B. C.; Della-Casa, M. S.; Sampaio, S. C.; Goncalves, L. R. C.; Cirillo, M. C.
Source: Self-asserted source
Luis Goncalves via ResearcherID

Effect of plant neutrophil elastase inhibitor on leucocyte migration, adhesion and cytokine release in inflammatory conditions

British Journal of Pharmacology
2010 | Journal article
DOI: 10.1111/j.1476-5381.2010.00924.x
WOSUID:

WOS:000282179000014
Contributors: Oliveira, C.; Navarro-Xavier, R. A.; Anjos-Vallota, E. A.; Martins, J. O.; Silveira, V. L. F.; Goncalves, L. R. C.; Araujo, M. S.; Motta, G.; Sannomiya, P.; Oliva, M. L. V.
Source: Self-asserted source
Luis Goncalves via ResearcherID

Preclinical assessment of the neutralizing capacity of antivenoms produced in six Latin American countries against medically-relevant Bothrops snake venoms

Toxicon
2010 | Journal article
DOI: 10.1016/j.toxicon.2010.07.001
WOSUID:

WOS:000282253900014
Contributors: Segura, A.; Castillo, M. C.; Nunez, V.; Yarleque, A.; Goncalves, L. R. C.; Villalta, M.; Bonilla, C.; Herrera, M.; Vargas, M.; Fernandez, M. et al.
Source: Self-asserted source
Luis Goncalves via ResearcherID

Crotoxin alters lymphocyte distribution in rats: Involvement of adhesion molecules and lipoxygenase-derived mediators

Toxicon
2008 | Journal article
DOI: 10.1016/j.toxicon.2008.03.004
WOSUID:

WOS:000257645200005
Contributors: Zambelli, Vanessa O.; Sampaio, Sandra C.; Sudo-Hayashi, Lia S.; Greco, Karin; Britto, Luiz R. G.; Alves, Adilson S.; Zychar, Bianca C.; Goncalves, Luis R. C.; Spadacci-Morena, Diva D.; Otton, Rosemari et al.
Source: Self-asserted source
Luis Goncalves via ResearcherID

Phenol used as a preservative in Bothrops antivenom induces impairment in leukocyte-endothelial interactions

Toxicon
2008 | Journal article
DOI: 10.1016/j.toxicon.2008.01.016
WOSUID:

WOS:000256999600003
Contributors: Zychar, Bianca Cestari; Castro, Norberto Carone, Jr.; Marcelino, Jose Roberto; Goncalves, Luis Roberto C.
Source: Self-asserted source
Luis Goncalves via ResearcherID
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Preferred source (of 2)‎

Effect of dexamethasone associated with serum therapy on treatment of Bothrops jararaca venom-induced paw edema in mice

Inflammation Research
2007 | Journal article
DOI: 10.1007/s00011-007-7054-x
WOSUID:

WOS:000250513500003
Contributors: Araujo, S. Dias; de Souza, A.; Nunes, R. P. B.; Goncalves, L. R. C.
Source: Self-asserted source
Luis Goncalves via ResearcherID

Efficacy of serum therapy on the treatment of rats experimentally envenomed by bristle extract of the caterpillar Lonomia obliqua: Comparison with epsilon-aminocaproic acid therapy

Toxicon
2007 | Journal article
DOI: 10.1016/j.toxicon.2007.04.004
WOSUID:

WOS:000249172400005
Contributors: Goncalves, Luis Roberto C.; Sousa-e-Silva, M. Cristina C.; Torny, Sandra C.; Sano-Martins, Ida S.
Source: Self-asserted source
Luis Goncalves via ResearcherID

Purification and characterization of patagonfibrase, a metalloproteinase showing alpha-fibrinogenolytic and hemorrhagic activities, from Philodryas patagoniensis snake venom

Biochimica Et Biophysica Acta-General Subjects
2007 | Journal article
DOI: 10.1016/j.bbagen.2006.12.014
WOSUID:

WOS:000245832500010
Contributors: Peichoto, M. E.; Teibler, P.; Mackessy, S. P.; Leiva, L.; Acosta, O.; Goncalves, L. R. C.; Tanaka-Azevedo, A. M.; Santoro, M. L.
Source: Self-asserted source
Luis Goncalves via ResearcherID

Effects of Lonomia obliqua (lepidoptera, saturniidae) toxin on clotting, inflammatory and antibody responsiveness in genetically selected lines of mice

Toxicon
2004 | Journal article
DOI:

10.1016/j.toxicon.2004.03.010

Part of ISSN:

0041-0101
Contributors: Ramos, A. T.; Goncalves, L. R. C.; Ribeiro, O. G.; Campos, A. C. R.; Sant'Anna, O. A.
Source: Self-asserted source
Luis Goncalves via ResearcherID

High molecular mass kininogen inhibits metalloproteinases of Bothrops jararaca snake venom

Biochemical and Biophysical Research Communications
2004 | Journal article
DOI: 10.1016/j.bbrc.2004.03.182
WOSUID:

WOS:000221254200009
Contributors: Goncalves, L. R. C.; Chudzinski-Tavassi, A. M.
Source: Self-asserted source
Luis Goncalves via ResearcherID

Intravascular hemolysis induced by Lonomia obliqua caterpillar bristle extract: an experimental model of envenomation in rats

Toxicon
2004 | Journal article
DOI: 10.1016/j.toxicon.2004.08.019
WOSUID:

WOS:000225053300010
Contributors: Seibert, C. S.; Oliveira, M. R. L.; Goncalves, L. R. C.; Santoro, M. L.; Sano-Martins, I. S.
Source: Self-asserted source
Luis Goncalves via ResearcherID

The C-terminus of murine S100A9 inhibits hyperalgesia and edema induced by jararhagin

Peptides
2004 | Journal article
DOI: 10.1016/j.peptides.2003.12.008
WOSUID:

WOS:000220267900011
Contributors: Dale, C. S.; Goncalves, L. R. C.; Juliano, L.; Juliano, M. A.; da Silva, A. M. M.; Giorgi, R.
Source: Self-asserted source
Luis Goncalves via ResearcherID
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Specific heterologous F(ab ')(2) antibodies revert blood incoagulability resulting from envenoming by Lonomia obliqua caterpillars

American Journal of Tropical Medicine and Hygiene
2001 | Journal article
WOSUID:

WOS:000169921600012
Contributors: Rocha-Campos, A. C. M.; Goncalves, L. R. C.; Higashi, H. C.; Yamagushi, I. K.; Fernandes, I.; Oliveira, J. E.; Ribela, Mtcp; Sousa-E-Silva, M. C. C.; Da Silva, W. D.
Source: Self-asserted source
Luis Goncalves via ResearcherID

Bothrops asper snake venom and its metalloproteinase BaP-1 activate the complement system. Role in leucocyte recruitment

Mediators of Inflammation
2000 | Journal article
WOSUID:

WOS:000165928300001
Contributors: Farsky, S. H. P.; Goncalves, L. R. C.; Gutierrez, J. M.; Correa, A. P.; Rucavado, A.; Gasque, P.; Tambourgi, D. V.
Source: Self-asserted source
Luis Goncalves via ResearcherID

Local haemorrhage induced by Bothrops jararaca venom: relationship to neurogenic inflammation

Mediators of Inflammation
2000 | Journal article
DOI:

10.1080/096293500411569

Part of ISSN:

0962-9351
Contributors: Goncalves, L. R. C.; Mariano, M.
Source: Self-asserted source
Luis Goncalves via ResearcherID
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Characterization of local tissue damage evoked by Bothrops jararaca venom in the rat connective tissue microcirculation: an intravital microscopic study

Toxicon
1999 | Journal article
DOI: 10.1016/s0041-0101(98)00241-4
WOSUID:

WOS:000080532600010
Contributors: Farsky, S. H. P.; Goncalves, L. R. C.; Cury, Y.
Source: Self-asserted source
Luis Goncalves via ResearcherID

Comparison of the biological activities in venoms from three subspecies of the South American rattlesnake (Crotalus durissus terrificus, C-durissus cascavella and C-durissus collilineatus)

Comparative Biochemistry and Physiology C-Toxicology & Pharmacology
1999 | Journal article
DOI: 10.1016/s0742-8413(98)10079-8
WOSUID:

WOS:000078250700007
Contributors: Santoro, M. L.; Sousa-e-Silva, M. C. C.; Goncalves, L. R. C.; Almeida-Santos, S. M.; Cardoso, D. F.; Laporta-Ferreira, I. L.; Saiki, M.; Peres, C. A.; Sano-Martins, I. S.
Source: Self-asserted source
Luis Goncalves via ResearcherID

Comparative study of the venoms of three subspecies of Lachesis muta (bushmaster) from Brazil, Colombia and Costa Rica

Toxicon
1998 | Journal article
DOI:

10.1016/S0041-0101(98)00089-0

Part of ISSN:

0041-0101
Contributors: Otero, R.; Furtado, M. D. D.; Goncalves, L. R. C.; Nunez, V.; Garcia, M. E.; Osorio, R. G.; Romero, M.; Gutierrez, J. M.
Source: Self-asserted source
Luis Goncalves via ResearcherID
grade
Preferred source (of 2)‎

Detection of calcium-binding proteins in venom and Duvernoy's glands of South American snakes and their secretions

Comparative Biochemistry and Physiology C-Toxicology & Pharmacology
1997 | Journal article
WOSUID:

WOS:A1997YJ80900014
Contributors: Goncalves, L. R. C.; Yamanouye, N.; NunezBurgos, G. B.; Furtado, M. F. D.; Britto, L. R. G.; Nicolau, J.
Source: Self-asserted source
Luis Goncalves via ResearcherID

Development of an antivenom against toxins of Lonomia obliqua caterpillars

Toxicon
1996 | Journal article
DOI: 10.1016/0041-0101(96)00052-9
WOSUID:

WOS:A1996VL39000008
Contributors: daSilva, W. D.; Campos, Acmr; Goncalves, L. R. C.; SousaeSilva, M. C. C.; Higahsi, H. G.; Yamagushi, I. K.; Kelen, E. M. A.
Source: Self-asserted source
Luis Goncalves via ResearcherID
grade
Preferred source (of 2)‎

The venom of South American rattlesnakes inhibits macrophage functions and is endowed with anti-inflammatory properties

Mediators of Inflammation
1996 | Journal article
DOI: 10.1155/s0962935196000038
WOSUID:

WOS:A1996UB56500003
Contributors: Silva, Mccd; Goncalves, L. R. C.; Mariano, M.
Source: Self-asserted source
Luis Goncalves via ResearcherID

HIGH INHIBITORY ACTIVITY ON PROTEASES IN A REPTILE PLASMA (BOTHROPS-JARARACA SNAKE) IMPAIRS ITS INTRINSIC FIBRINOLYTIC-LIKE MECHANISM

Fibrinolysis
1995 | Journal article
DOI: 10.1016/s0268-9499(95)80068-9
WOSUID:

WOS:A1995QQ39400003
Contributors: Chudzinskitavassi, A. M.; Polizello, A. C. M.; Goncalves, L. R. C.; Rothschild, Z.; Kelen, E. M. A.
Source: Self-asserted source
Luis Goncalves via ResearcherID

ALTERATION OF THE PROTEIN-COMPOSITION OF BOTHROPS-JARARACA VENOM AND VENOM GLAND BY ISOPROTERENOL TREATMENT

International Journal of Biochemistry
1993 | Journal article
WOSUID:

WOS:A1993LZ56500015
Contributors: Burgos, G. B. N.; Goncalves, L. R. C.; Furtado, M. F. D.; Fernandes, W.; Nicolau, J.
Source: Self-asserted source
Luis Goncalves via ResearcherID

THE EFFICACY OF THE BOTHROPIC-CROTALIC ANTIVENOM ON THE NEUTRALIZATION OF THE MAIN BOTHROPS-JARARACUSSU VENOM ACTIVITIES

Revista Do Instituto De Medicina Tropical De Sao Paulo
1992 | Journal article
WOSUID:

WOS:A1992JE78100001
Contributors: Dossantos, M. C.; Goncalves, L. R. C.; Fortesdias, C. L.; Cury, Y.; Gutierrez, J. M.; Furtado, M. D. D.
Source: Self-asserted source
Luis Goncalves via ResearcherID

Peer review (11 reviews for 4 publications/grants)

Review activity for Journal of ethnopharmacology. (2)
Review activity for PLoS neglected tropical diseases (7)
Review activity for Toxicon. (1)
Review activity for Toxins. (1)
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