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Works (24)

Encapsulation of copper phenanthroline within horse spleen apoferritin: characterisation, cytotoxic activity and ability to retain temozolomide

RSC Advances
2024 | Journal article
DOI: 10.1039/D3RA07430G
Contributors: Maria Letizia Cassioli; Michael Fay; Lyudmila Turyanska; Tracey D. Bradshaw; Neil R. Thomas; Anca Pordea
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Cannabidiol and fluorinated derivative anti-cancer properties against glioblastoma multiforme cell lines, and synergy with imidazotetrazine agents

BJC Reports
2024-09-09 | Journal article
DOI: 10.1038/s44276-024-00088-0
Contributors: Alice Brookes; Nicholas Kindon; David J. Scurr; Morgan R. Alexander; Pavel Gershkovich; Tracey D. Bradshaw
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Conofolidine: A Natural Plant Alkaloid That Causes Apoptosis and Senescence in Cancer Cells

Molecules
2024-06-04 | Journal article
DOI: 10.3390/molecules29112654
Contributors: Mohammed Zuhair Al-Hayali; Choy-Eng Nge; Kuan Hon Lim; Hilary M. Collins; Toh-Seok Kam; Tracey D. Bradshaw
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Probing the Mechanism of Action of Bis(phenolato) Amine (ONO Donor Set) Titanium(IV) Anticancer Agents

Journal of Medicinal Chemistry
2024-02-22 | Journal article
DOI: 10.1021/acs.jmedchem.3c01874
Contributors: Mustapha Musa; Mohammed Abid; Tracey D. Bradshaw; David J. Boocock; Clare Coveney; Stephen P. Argent; Simon Woodward
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Correction to “Apoferritin-Encapsulated Jerantinine A for Transferrin Receptor Targeting and Enhanced Selectivity in Breast Cancer Therapy”

ACS Omega
2024-01-09 | Journal article
DOI: 10.1021/acsomega.3c09291
Contributors: Haneen Abuzaid; Salah Abdelrazig; Lenny Ferreira; Hilary M. Collins; Dong-Hyun Kim; Kuan-Hon Lim; Toh-Seok Kam; Neil R. Thomas; Lyudmila Turyanska; Tracey D. Bradshaw
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Conofolidine, a Natural Plant Alkaloid Causes Apoptosis and Senescence in Cancer Cells

2024-01-08 | Preprint
DOI: 10.20944/preprints202401.0602.v1
Contributors: Mohammed Zuhair Al-Hayali; Choy-Eng Nge; Kuan Hon Lim; Hilary M Collins; Toh Seok Kam; Tracey Dawn Bradshaw
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Highly electron deficient diketopyrrolopyrroles

Chemical Communications
2023 | Journal article
DOI: 10.1039/D2CC06770F
Contributors: Joshua Humphreys; Ferdinando Malagreca; Paul A. Hume; E. Stephen Davies; Stephen P. Argent; Tracey D. Bradshaw; David B. Amabilino
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Oral lipid-based formulations alter delivery of cannabidiol to different anatomical regions in the brain

International Journal of Pharmaceutics
2023-03 | Journal article
DOI: 10.1016/j.ijpharm.2023.122651
Contributors: Alice Brookes; Adelaide Jewell; Wanshan Feng; Tracey D. Bradshaw; James Butler; Pavel Gershkovich
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Design, and synthesis of selectively anticancer 4-cyanophenyl substituted thiazol-2-ylhydrazones

RSC Advances
2022 | Journal article
DOI: 10.1039/D2RA03226K
Contributors: Hasnain Mehmood; Mustapha Musa; Simon Woodward; Md Shahadat Hossan; Tracey D. Bradshaw; Muhammad Haroon; Andrew Nortcliffe; Tashfeen Akhtar
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In Vitro Anticancer Properties of Novel Bis-Triazoles

Current Issues in Molecular Biology
2022-12-29 | Journal article
DOI: 10.3390/cimb45010014
Contributors: Maysaa M. Saleh; Duaa A. Abuarqoub; Alaa M. Hammad; Md Shahadat Hossan; Najneen Ahmed; Nazneen Aslam; Abdallah Y. Naser; Christopher J. Moody; Charles A. Laughton; Tracey D. Bradshaw
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Apoferritin-Encapsulated Jerantinine A for Transferrin Receptor Targeting and Enhanced Selectivity in Breast Cancer Therapy

ACS Omega
2022-06-28 | Journal article
DOI: 10.1021/acsomega.2c00997
Contributors: Haneen Abuzaid; Salah Abdelrazig; Lenny Ferreira; Hilary M. Collins; Dong-Hyun Kim; Kuan-Hon Lim; Toh-Seok Kam; Lyudmila Turyanska; Tracey D. Bradshaw
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Near-infrared PbS quantum dots functionalized with affibodies and ZnPP for targeted imaging and therapeutic applications

Nano Express
2021-12-01 | Journal article
DOI: 10.1088/2632-959X/ac33b8
Contributors: Ali W Al-Ani; Francesco Zamberlan; Lenny Ferreira; Tracey D Bradshaw; Neil R Thomas; Lyudmila Turyanska
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Chemosensitization of Temozolomide-Resistant Pediatric Diffuse Midline Glioma Using Potent Nanoencapsulated Forms of a N(3)-Propargyl Analogue

ACS Applied Materials & Interfaces
2021-08-04 | Journal article
DOI: 10.1021/acsami.1c04164
Contributors: Vahid Heravi Shargh; Jeni Luckett; Kaouthar Bouzinab; Stephen Paisey; Lyudmila Turyanska; William G. B. Singleton; Stephen Lowis; Pavel Gershkovich; Tracey D. Bradshaw; Malcolm F. G. Stevens et al.
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Structure-based design of highly selective 2,4,5-trisubstituted pyrimidine CDK9 inhibitors as anti-cancer agents

European Journal of Medicinal Chemistry
2021-03 | Journal article
DOI: 10.1016/j.ejmech.2021.113244
Contributors: Hao Shao; David W. Foley; Shiliang Huang; Abdullahi Y. Abbas; Frankie Lam; Pavel Gershkovich; Tracey D. Bradshaw; Chris Pepper; Peter M. Fischer; Shudong Wang
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Delivery of Temozolomide and N3-Propargyl Analog to Brain Tumors Using an Apoferritin Nanocage

ACS Applied Materials & Interfaces
2020-03-18 | Journal article
DOI: 10.1021/acsami.0c01514
Contributors: Kaouthar Bouzinab; Helen S. Summers; Malcolm F. G. Stevens; Christopher J. Moody; Neil R. Thomas; Pavel Gershkovich; Nicola Weston; Marianne B. Ashford; Tracey D. Bradshaw; Lyudmila Turyanska
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The antitumour activity of 2‐(4‐amino‐3‐methylphenyl)‐5‐fluorobenzothiazole in human gastric cancer models is mediated by AhR signalling

Journal of Cellular and Molecular Medicine
2020-01 | Journal article
DOI: 10.1111/jcmm.14869
Contributors: Yuling Wang; Ying Liu; Tao Tang; Ying Luo; Malcolm F. G. Stevens; Xi Cheng; Yan Yang; Dongfang Shi; Jihong Zhang; Tracey D. Bradshaw
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Apoferritin encapsulation of cysteine protease inhibitors for cathepsin L inhibition in cancer cells

RSC Advances
2019 | Journal article
DOI: 10.1039/C9RA07161J
Contributors: José C. Quilles Junior; Fernanda dos Reis Rocho Carlos; A. Montanari; Andrei Leitão; Viviane W. Mignone; Maria Augusta Arruda; Lyudmila Turyanska; Tracey D. Bradshaw
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<p>Protein Encapsulation of Experimental Anticancer Agents 5F 203 and Phortress: Towards Precision Drug Delivery</p>

International Journal of Nanomedicine
2019-12 | Journal article
DOI: 10.2147/IJN.S226293
Contributors: Alastair F Breen; David Scurr; Maria Letizia Cassioli; Geoffrey Wells; Neil R Thomas; Jihong Zhang; Lyudmila Turyanska; Tracey D Bradshaw
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Development of novel apoferritin formulations for antitumour benzothiazoles

Cancer Reports
2019-08 | Journal article
DOI: 10.1002/cnr2.1155
Contributors: Alastair F. Breen; Geoffrey Wells; Lyudmila Turyanska; Tracey D. Bradshaw
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Synthesis and growth-inhibitory activities of imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamides related to the anti-tumour drug temozolomide, with appended silicon, benzyl and heteromethyl groups at the 3-position

MedChemComm
2018 | Journal article
DOI: 10.1039/C7MD00554G
Contributors: David Cousin; Marc G. Hummersone; Tracey D. Bradshaw; Jihong Zhang; Christopher J. Moody; Magdalena B. Foreiter; Helen S. Summers; William Lewis; Richard T. Wheelhouse; Malcolm F. G. Stevens
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Autophagy modulation: a prudent approach in cancer treatment?

Cancer Chemotherapy and Pharmacology
2018-12 | Journal article
DOI: 10.1007/s00280-018-3669-6
Contributors: Eleanor Bishop; Tracey D. Bradshaw
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Frontispiece: Synthesis of Highly Substituted 1,2‐Diazetidin‐3‐ones, Small‐Ring Scaffolds for Drug Discovery

Chemistry – A European Journal
2018-06-12 | Journal article
DOI: 10.1002/chem.201883365
Contributors: Marilia S. Santos; Andrew Nortcliffe; William Lewis; Tracey D. Bradshaw; Christopher J. Moody
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Synthesis of Highly Substituted 1,2‐Diazetidin‐3‐ones, Small‐Ring Scaffolds for Drug Discovery

Chemistry – A European Journal
2018-06-12 | Journal article
DOI: 10.1002/chem.201801309
Contributors: Marilia S. Santos; Andrew Nortcliffe; William Lewis; Tracey D. Bradshaw; Christopher J. Moody
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Development of a series of bis-triazoles as G-quadruplex ligands

RSC Advances
2017 | Journal article
DOI: 10.1039/C7RA07257K
Contributors: Maysaa M. Saleh; Charles A. Laughton; Tracey D. Bradshaw; Christopher J. Moody
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