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Hong Kong SAR China

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Hong Kong University of Science and Technology: Hong Kong, HK

Assistant Professor, Department of Chemistry; Assistant Professor, Environmental Science Programs (ENVS), Office of the Dean of Science
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Hong Kong University of Science and Technology

Works (50 of 85)

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Bisphenol A in Disposable Face Masks: A Novel Human Exposure Pathway and Impact on the Aquatic Environment

Chemical Research in Toxicology
2025-02-17 | Journal article
Contributors: Hei-Tak Tse; Chun-Kit Au; Wan Chan
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Crossref

Absorptivity Is an Important Determinant in the Toxicity Difference between Aristolochic Acid I and Aristolochic Acid II

Journal of Agricultural and Food Chemistry
2025-01-29 | Journal article
Contributors: Hong-Ching Kwok; Hei-Tak Tse; Ka-Ki Ng; Shuangshuang Wang; Chun-Kit Au; Zongwei Cai; Wan Chan
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Crossref

Redox and Photochemical Reactivity of Cerium(IV) Carbonate and Carboxylate Complexes Supported by a Tripodal Oxygen Ligand

Inorganic Chemistry
2025-01-27 | Journal article
Contributors: Hoang-Long Pham; Xinxin Jiang; Qiaolin Yan; Yat-Ming So; Wan Chan; Herman H. Y. Sung; Ian D. Williams; Wa-Hung Leung
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Crossref

Aristolochic Acids and Aristoloxazines Are Widespread in the Soil of Aristolochiaceae Herb Cultivation Fields

Environmental Science & Technology
2024-12-24 | Journal article
Contributors: Man-Lung Chin; Haoyu Zhang; Chun-Kit Au; Wing-Laam Luk; Zongwei Cai; Wan Chan
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Crossref

Surgical Face Mask as an Air Sampling Device for Assessing Personal Exposure to Airborne Antimicrobial Resistance Gene-Bearing Bacteria

Analytical Chemistry
2024-10-22 | Journal article
Contributors: Yat-Hing Ham; Jinping Cheng; Stefan Nagl; Jian Zhen Yu; Zongwei Cai; Wan Chan
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Crossref

Using 2-(2-Chlorophenyl)thiazolidine-4-carboxylic Acid as a Novel Biomarker for 2-Chlorobenzalmalononitrile Exposure

Chemical Research in Toxicology
2024-10-21 | Journal article
Contributors: Guanrui Pan; Hei-Tak Tse; Ho-Wai Chan; Wan Chan
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Crossref

Urinary Thioproline and Thioprolinyl Glycine as Specific Biomarkers of Formaldehyde Exposure in Humans

Environmental Science & Technology
2024-09-17 | Journal article
Contributors: Guanrui Pan; Chun-Kit Au; Yat-Hing Ham; Jian Zhen Yu; Zongwei Cai; Wan Chan
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Crossref

Positive Feedback Mechanism in Aristolochic Acid I Exposure-Induced Anemia and DNA Adduct Formation: Implications for Balkan Endemic Nephropathy

Journal of Agricultural and Food Chemistry
2024-08-14 | Journal article
Contributors: Yat-Hing Ham; Man-Lung Chin; Guanrui Pan; Shuangshuang Wang; Nikola M. Pavlović; Wan Chan
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Crossref

Combustion-Derived Pollutants Linked with Kidney Disease in Low-Lying Flood-Affected Areas in the Balkans

Environmental Science & Technology
2024-07-02 | Journal article
Contributors: Wanlin Guo; Hong Ching Kwok; Stephen M. Griffith; Stefan Nagl; Dragan Milovanović; Miljana Pavlović; Nikola M. Pavlović; Jian Zhen Yu; Peter C. Dedon; Wan Chan
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Crossref

Aristolochic Acid Exposure via Dermal Contact or Inhalation of Herbal Powders: Evidence of Occupational Exposure in Herbalists with Urothelial Cancer

Chemical Research in Toxicology
2024-06-17 | Journal article
Contributors: Hong-Ching Kwok; Wan Chan
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Crossref

Effects of Heavy Metal Co-Exposure on the formation of DNA Adducts from Aristolochic Acid I: Implications for Balkan Endemic Nephropathy Development

Chemical Research in Toxicology
2024-04-15 | Journal article
Contributors: Chun-Kit Au; Stefan Nagl; Wan Chan
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Crossref

Fabrication of a Simple and Efficient HPLC Reduction Column for Online Conversion of Aristolochic Acids to Aristolactams Prior to Sensitive Fluorescence Detection

Analytical Chemistry
2023-08-22 | Journal article
Contributors: Man-Lung Chin; Chun-Kit Au; Chi-Kong Chan; Long Jin; Milena Z. Živković Stošić; Miljana R. Đorđević Zlatković; Dragan Zlatković; Nikola M. Pavlović; Wan Chan
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Crossref

Face Mask as a Versatile Sampling Device for the Assessment of Personal Exposure to 54 Toxic Compounds in Environmental Tobacco Smoke

Chemical Research in Toxicology
2023-07-17 | Journal article
Contributors: Wanlin Guo; Jian Zhen Yu; Wan Chan
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Crossref

Effects of Diet on Aristolochic Acid-DNA Adduct Formation: Implications for Balkan Endemic Nephropathy Etiology

Chemical Research in Toxicology
2023-03-20 | Journal article
Contributors: Jiayin Zhang; Chi-Kong Chan; Nikola M. Pavlović; Wan Chan
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Crossref

Bioaccumulation and DNA Adduct Formation of Aristolactam I: Unmasking a Toxicological Mechanism in the Pathophysiology of Aristolochic Acid Nephropathy

Chemical Research in Toxicology
2023-02-20 | Journal article
Contributors: Chun-Kit Au; Yat-Hing Ham; Wan Chan
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Crossref

Polyurethane Foam Face Masks as a Dosimeter for Quantifying Personal Exposure to Airborne Volatile and Semi-Volatile Organic Compounds

Chemical Research in Toxicology
2022-09-19 | Journal article
Contributors: Zhihan Sun; Wanlin Guo; Chi-Kong Chan; Long Jin; Stephen M. Griffith; Jian Zhen Yu; Wan Chan
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Crossref

Wheatgrass (Triticum aestivum) as an Efficient Phytoremediation Plant for Aristolochic Acid-Contaminated Water and Arable Soil

ACS Agricultural Science & Technology
2022-06-20 | Journal article
Contributors: Hong-Ching Kwok; Wan Chan
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Crossref

LC-MS/MS Quantitation of Formaldehyde–Glutathione Conjugates as Biomarkers of Formaldehyde Exposure and Exposure-Induced Antioxidants: A New Look on an Old Topic

Chemical Research in Toxicology
2022-05-16 | Journal article
Contributors: Yat-Hing Ham; Guanrui Pan; Ho Wai Chan; Wan Chan
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Crossref

Synergistic Interaction of Polycyclic Aromatic Hydrocarbons, Phthalate Esters, or Phenol on DNA Adduct Formation by Aristolochic Acid I: Insights into the Etiology of Balkan Endemic Nephropathy

Chemical Research in Toxicology
2022-05-16 | Journal article
Contributors: Jiayin Zhang; Kwan-Kit Jason Chan; Wan Chan
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Crossref

DNA–Protein Cross-Links Formed by Reacting Lysine with Apurinic/Apyrimidinic Sites in DNA and Human Cells: Quantitative Analysis by Liquid Chromatography–Tandem Mass Spectrometry Coupled with Stable Isotope Dilution

Analytical Chemistry
2022-01-18 | Journal article
Contributors: Wan Chan; Long Jin
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Crossref

On the Flip Side of Mask Wearing: Increased Exposure to Volatile Organic Compounds and a Risk-Reducing Solution

Environmental Science & Technology
2021-10-19 | Journal article
Contributors: Long Jin; Stephen M. Griffith; Zhihan Sun; Jian Zhen Yu; Wan Chan
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Crossref

Polyurethane-Based Face Mask as a Sampling Device for Environmental Tobacco Smoke

Analytical Chemistry
2021-10-19 | Journal article
Contributors: Wan Chan; Wanlin Guo; Jian Zhen Yu
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Crossref

Determination of Aristolochic Acids in Soil, Water, and Herbal Plants in Medicinal Plant Cultivation Areas: An Emerging Environmental Contaminant Worth Concerning

ACS Agricultural Science & Technology
2021-10-18 | Journal article
Contributors: Chi-Kong Chan; Lei Xiong; Nikola M. Pavlović; Wan Chan
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Crossref

Probing the Hidden Role of Mitochondrial DNA Damage and Dysfunction in the Etiology of Aristolochic Acid Nephropathy

Chemical Research in Toxicology
2021-08-16 | Journal article
Contributors: Wan Chan; Yat-Hing Ham
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Crossref

Quantitation of γ-Glutamylcysteine–Formaldehyde Conjugate in Formaldehyde- and Oxidative Stress-Exposed Cells by Liquid Chromatography–Tandem Mass Spectrometry

Chemical Research in Toxicology
2021-07-19 | Journal article
Contributors: Yao Zhao; Wan Chan
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Crossref

Analysis of Polycyclic Aromatic Hydrocarbons and Phthalate Esters in Soil and Food Grains from the Balkan Peninsula: Implication on DNA Adduct Formation by Aristolochic Acid I and Balkan Endemic Nephropathy

Environmental Science & Technology
2021-07-06 | Journal article
Contributors: Wanlin Guo; Jiayin Zhang; Zhihan Sun; William H. Orem; Calin A. Tatu; Niko S. Radulović; Dragan Milovanović; Nikola M. Pavlović; Wan Chan
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Crossref

Formation, Stability, and Antioxidative Properties of 2-Methylthioproline and 2-Methylthioprolineglycine in Grape Wines

ACS Food Science & Technology
2021-06-18 | Journal article
Contributors: Wan Chan; Yao Zhao; Kwan-Kit Jason Chan
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Crossref

Analysis of aristolochic acids in Houttuynia cordata by liquid chromatography–tandem mass spectrometry

Journal of Mass Spectrometry
2021-04 | Journal article
Contributors: Chi‐Kong Chan; Guanrui Pan; Wan Chan
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Crossref

Fabric Masks as a Personal Dosimeter for Quantifying Exposure to Airborne Polycyclic Aromatic Hydrocarbons

Environmental Science & Technology
2021-04-20 | Journal article
Contributors: Wan Chan; Long Jin; Zhihan Sun; Stephen M. Griffith; Jian Zhen Yu
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Crossref

Quantitation of Protein Adducts of Aristolochic Acid I by Liquid Chromatography–Tandem Mass Spectrometry: A Novel Method for Biomonitoring Aristolochic Acid Exposure

Chemical Research in Toxicology
2021-01-18 | Journal article
Contributors: Chi-Kong Chan; Kwan-Kit Jason Chan; Ning Liu; Wan Chan
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Crossref

Proteomics Study of DNA–Protein Crosslinks in Methylmethanesulfonate and Fe2+-EDTA-Exposed Human Cells

Chemical Research in Toxicology
2020-11-16 | Journal article
Contributors: Yat-Hing Ham; K. K. Jason Chan; Dominik Madej; Henry Lam; Wan Chan
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Crossref

Determination of Aristolochic Acids in Vegetables: Nephrotoxic and Carcinogenic Environmental Pollutants Contaminating a Broad Swath of the Food Supply and Driving Incidence of Balkan Endemic Nephropathy

Chemical Research in Toxicology
2020-09-21 | Journal article
Contributors: Chun-Kit Au; Jiayin Zhang; Chi-Kong Chan; Cui Li; Guorui Liu; Nikola M. Pavlović; Jing Yao; Wan Chan
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Crossref

LC-MS/MS Coupled with a Stable-Isotope Dilution Method for the Quantitation of Thioproline-Glycine: A Novel Metabolite in Formaldehyde- and Oxidative Stress-Exposed Cells

Chemical Research in Toxicology
2020-07-20 | Journal article
Contributors: Guanrui Pan; Yat-Hing Ham; Ho Wai Chan; Jing Yao; Wan Chan
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Crossref

Thioproline Serves as an Efficient Antioxidant Protecting Human Cells from Oxidative Stress and Improves Cell Viability

Chemical Research in Toxicology
2020-07-20 | Journal article
Contributors: Yat-Hing Ham; K. K. Jason Chan; Wan Chan
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Crossref

Identifying Cysteine, N-Acetylcysteine, and Glutathione Conjugates as Novel Metabolites of Aristolochic Acid I: Emergence of a New Detoxification Pathway

Chemical Research in Toxicology
2020-06-15 | Journal article
Contributors: Jiayin Zhang; Chi-Kong Chan; Yat-Hing Ham; Wan Chan
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Crossref

Quantitation of DNA Adducts of Aristolochic Acids in Repair-Deficient Cells: A Mechanistic Study of the DNA Repair Mechanism

Chemical Research in Toxicology
2020-06-15 | Journal article
Contributors: Chun-Kit Au; Chi-Kong Chan; Ka-Ki Tung; Jiayin Zhang; Wan Chan
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Crossref

Liquid chromatography–tandem mass spectrometry analysis of aristolochic acids in soil samples collected from Serbia: Link to Balkan endemic nephropathy

Rapid Communications in Mass Spectrometry
2020-04 | Journal article
Contributors: Chi‐Kong Chan; K.K. Jason Chan; Nikola M. Pavlović; Wan Chan
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Crossref

Occurrence and Environmental Stability of Aristolochic Acids in Groundwater Collected from Serbia: Links to Human Exposure and Balkan Endemic Nephropathy

Environmental Science & Technology
2020-02-04 | Journal article
Contributors: Ka-Ki Tung; Chi-Kong Chan; Yao Zhao; Kwan-Kit Jason Chan; Guorui Liu; Nikola M. Pavlović; Wan Chan
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Crossref

Quantitation of N6-Formyl-lysine Adduct Following Aristolochic Acid Exposure in Cells and Rat Tissues by Liquid Chromatography-Tandem Mass Spectrometry Coupled with Stable Isotope-Dilution Method

Chemical Research in Toxicology
2019-10-21 | Journal article
Contributors: Yao Zhao; Chi-Kong Chan; K. K. Jason Chan; Wan Chan
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Crossref

Quantification of a Novel DNA–Protein Cross-Link Product Formed by Reacting Apurinic/Apyrimidinic Sites in DNA with Cysteine Residues in Protein by Liquid Chromatography-Tandem Mass Spectrometry Coupled with the Stable Isotope-Dilution Method

Analytical Chemistry
2019-04-16 | Journal article
Contributors: Wan Chan; Yat-Hing Ham; Long Jin; Ho Wai Chan; Yee-Lam Wong; Chi-Kong Chan; Pui-Yin Chung
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Crossref

Evaluating the performance of sample preparation methods for ultra‐performance liquid chromatography/mass spectrometry based serum metabonomics

Rapid Communications in Mass Spectrometry
2019-03-30 | Journal article
Contributors: Wan Chan; Yao Zhao; Jiayin Zhang
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Crossref

Quantitation of DNA Adducts in Target and Nontarget Organs of Aristolochic Acid I-Exposed Rats: Correlating DNA Adduct Levels with Organotropic Activities

Chemical Research in Toxicology
2019-03-18 | Journal article
Contributors: Yushuo Liu; Chi-Kong Chan; Long Jin; Sum-Kok Wong; Wan Chan
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Crossref

Investigation of the chemical structure and formation mechanism of polydopamine from self‐assembly of dopamine by liquid chromatography/mass spectrometry coupled with isotope‐labelling techniques

Rapid Communications in Mass Spectrometry
2019-03-15 | Journal article
Contributors: Wan Chan
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Crossref

Etiology of Balkan Endemic Nephropathy: An Update on Aristolochic Acids Exposure Mechanisms

Chemical Research in Toxicology
2018-11-19 | Journal article
Contributors: Chi-Kong Chan; Yushuo Liu; Nikola M. Pavlović; Wan Chan
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Crossref

Quantification of DNA and Protein Adducts of 1-Nitropyrene: Significantly Higher Levels of Protein than DNA Adducts in the Internal Organs of 1-Nitropyrene Exposed Rats

Chemical Research in Toxicology
2018-08-20 | Journal article
Contributors: Wan Chan; Sum-Kok Wong; Weiwei Li
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Crossref

Plant Uptake and Metabolism of Nitrofuran Antibiotics in Spring Onion Grown in Nitrofuran-Contaminated Soil

Journal of Agricultural and Food Chemistry
2017-05-31 | Journal article
Contributors: Yinan Wang; K. K. Jason Chan; Wan Chan
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Crossref

Development of a QuEChERS-Based Method for Determination of Carcinogenic 2-Nitrofluorene and 1-Nitropyrene in Rice Grains and Vegetables: A Comparative Study with Benzo[a]pyrene

Journal of Agricultural and Food Chemistry
2017-03-08 | Journal article
Contributors: Kailin Deng; Wan Chan
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Crossref

Comparison of DNA and RNA adduct formation: Significantly higher levels of RNA than DNA modifications in the internal organs of aristolochic acids-dosed rats.

Chemical Research Toxicology
2015 | Journal article
DOI:

10.1021/tx500423m

HANDLE:

1783.1/66388

Contributors: Leung, Ming Kit; Chan, Wan
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Hong Kong University of Science and Technology

A novel reversed-phase HPLC method for the determination of urinary creatinine by pre-column derivatization with ethyl chloroformate: comparative studies with the standard Jaff, and isotope-dilution mass spectrometric assays

Analytical and bioanalytical chemistry
2014 | Journal article
DOI:

10.1007/s00216-013-7592-8

HANDLE:

1783.1/60551

Contributors: Leung, Elvis Ming Kit; Chan, Wan
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Hong Kong University of Science and Technology

Determination of Aristolochic Acids by High-Performance Liquid Chromatography with Fluorescence Detection

Journal of agricultural and food chemistry
2014 | Journal article
DOI:

10.1021/jf501609j

HANDLE:

1783.1/61424

Contributors: Wang, Yinan; Chan, Wan
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Hong Kong University of Science and Technology
Items per page:
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Peer review (115 reviews for 9 publications/grants)

Review activity for ACS applied materials & interfaces. (2)
Review activity for ACS sensors. (1)
Review activity for Analytical chemistry. (19)
Review activity for Chemical research in toxicology. (64)
Review activity for Environmental science & technology letters. (2)
Review activity for Environmental science & technology. (7)
Review activity for Journal of agricultural and food chemistry. (17)
Review activity for Journal of medicinal chemistry. (2)
Review activity for Journal of the American Society for Mass Spectrometry. (1)