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United Kingdom

Biography

Miraz Rahman is a Professor of Medicinal Chemistry in School of Cancer & Pharmaceutical Sciences, King’s College London. After working three years in the industry, he went back to academia and obtained his PhD from the School of Pharmacy (currently UCL School of Pharmacy) in synthetic medicinal chemistry. His research activities are focused on the application of advanced computational chemistry, synthetic medicinal chemistry and chemical biology techniques to the design, synthesis and evaluation of novel drug-like chemical scaffolds as anticancer and anti-infective agents. He joined King’s College London in 2012 and currently holds the position of Chair in Medicinal Chemistry and Antimicrobial Research Theme Lead of Institute of Pharmaceutical Science. He is working with UK Health Security Agency to develop new generation efflux resistant antimicrobials and new chemical tools to study antimicrobial resistance (AMR). His research group has invented new classes of efflux resistant antibiotics and antifungal agents that are currently being commercialised. Professor Rahman has experience in both early and late-stage drug discovery and translational research, co-founding Transcriptogen Ltd (2013), Femtogenix Ltd (2015) and the antibiotic company Necobiotix Ltd (2020).

Activities

Employment (12)

King's College London: London, GB

Employment
Source: check_circle
King's College London

King's College London: London, GB

2021-10-01 to present | Professor of Medicinal Chemistry (Institute of Pharmaceutical Science)
Employment
Source: Self-asserted source
Khondaker Miraz Rahman

King's College London: London, GB

2018-09-01 to 2021-09-30 | Reader in Medicinal Chemistry (Institute of Pharmaceutical Science)
Employment
Source: Self-asserted source
Khondaker Miraz Rahman

King's College London: London, London, GB

2015-09-01 to 2018-08-31 | Senior Lecturer in Medicinal Chemistry (Institute of Pharmaceutical Science)
Employment
Source: Self-asserted source
Khondaker Miraz Rahman

King's College London: London, London, GB

2012-05-15 to 2015-08-31 | Lecturer in Medicinal Chemistry (Institute of Pharmaceutical Science)
Employment
Source: Self-asserted source
Khondaker Miraz Rahman

King's College London: London, London, GB

2012-01-01 to 2012-05-14 | Senior Research Fellow (Institute of Pharmaceutical Science)
Employment
Source: Self-asserted source
Khondaker Miraz Rahman

University College London: London, GB

2007-07-01 to 2011-12-31 | CRUK Post-doctoral Research Fellow (School of Pharmacy)
Employment
Source: Self-asserted source
Khondaker Miraz Rahman

University of Dhaka Faculty of Pharmacy: Dhaka, Dhaka District, BD

2005-06-01 to 2011-02-01 | Assistant Professor in Pharmaceutical Chemistry (Pharmaceutical Chemistry)
Employment
Source: Self-asserted source
Khondaker Miraz Rahman

University College London: London, GB

2008-12-01 to 2009-06-01 | Research Assitant (School of Pharmacy)
Employment
Source: Self-asserted source
Khondaker Miraz Rahman

University of Dhaka Faculty of Pharmacy: Dhaka, Dhaka District, BD

2003-10-01 to 2005-05-31 | Lecturer in Pharmaceutical Chemistry (Pharmaceutical Chemistry)
Employment
Source: Self-asserted source
Khondaker Miraz Rahman

University of Asia Pacific: Dhaka, Dhaka District, BD

2001-04-01 to 2003-09-01 | Lecturer in Pharmaceutical Chemistry (Pharmacy)
Employment
Source: Self-asserted source
Khondaker Miraz Rahman

Eskayef Bangladesh Limited: Dhaka, BD

1997-10-01 to 2001-03-31 | R&D Pharmacist (Research and Development)
Employment
Source: Self-asserted source
Khondaker Miraz Rahman

Education and qualifications (5)

King's College London: London, London, GB

2012-10-01 to 2014-06-01 | PGCAP HE (King's Learning Institute)
Education
Source: Self-asserted source
Khondaker Miraz Rahman

University College London: London, GB

2009-07-01 to 2011-12-31 | Post-doctoral Fellow (School of Pharmacy)
Education
Source: Self-asserted source
Khondaker Miraz Rahman

University College London: London, GB

2005-09-30 to 2009-10-31 | Ph D in Medicinal Chemistry (School of Pharmacy)
Education
Source: Self-asserted source
Khondaker Miraz Rahman

University of Dhaka Faculty of Pharmacy: Dhaka, Dhaka District, BD

1997-07-01 to 1999-04-30 | M Pharm (Pharmacy)
Education
Source: Self-asserted source
Khondaker Miraz Rahman

University of Dhaka Faculty of Pharmacy: Dhaka, Dhaka District, BD

1993-07-01 to 1997-06-30 | B Pharm (Pharmacy)
Education
Source: Self-asserted source
Khondaker Miraz Rahman

Funding (14)

Bisbiguanide analogues as probes for assessing membrane barrier function in multidrug resistant Gram-negative bacteria.

2021-10 to 2025-09 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
Source: Self-asserted source
Khondaker Miraz Rahman

Heme oxygenase-1 inhibition for the immunotherapy treatment of cancer’

2020-12 to 2021-12 | Grant
Medical Research Council (Swindon, GB)
Part of GRANT_NUMBER:

MC_PC_19041

Source: Self-asserted source
Khondaker Miraz Rahman

Synthesis of Analogues of the TrkB Antagonist A3

2020-10 to 2021-06 | Grant
Auris Medical (Basel, CH)
GRANT_NUMBER:

857506

Source: Self-asserted source
Khondaker Miraz Rahman

Identification of New Therapeutic Combinations for Clinical Trial against COVID-19 Through Repurposing of Drugs with Known Safety Profile.

2020-05 to 2020-12 | Grant
NIHR King's Biomedical Research Centre (London, GB)
GRANT_NUMBER:

RE16763

Source: Self-asserted source
Khondaker Miraz Rahman

The role of the anaplerotic node in redox homeostasis and pathogenesis of Mycobacterium tuberculosis and its exploitation as a therapeutic target

2020-03-01 to 2023-02-28 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/T007737/1
Source: Self-asserted source
Khondaker Miraz Rahman via DimensionsWizard

Exploring bias in platelet P2Y1 receptor signalling: host defence versus haemostasis.

2020-01 to 2022-12 | Grant
Medical Research Council (Swindon, GB)
Part of GRANT_NUMBER: MR/T015845/1
Source: Self-asserted source
Khondaker Miraz Rahman

Development of new antibiofilm agents through repurposing of existing licensed drugs

2019-11 to 2021-10 | Grant
National Biofilms Innovation Centre (Southampton, GB)
GRANT_NUMBER:

POC2-091

Source: Self-asserted source
Khondaker Miraz Rahman

Assessing the relevance of Galleria mellonella to antibiotic drug discovery for pulmonary infections

2019-07-14 to 2020-01-14 | Grant
National Centre for the Replacement Refinement and Reduction of Animals in Research (London, GB)
GRANT_NUMBER: NC/T001240/1
Source: Self-asserted source
Khondaker Miraz Rahman via DimensionsWizard

A combined, chemical-microbiology approach to understand the function of novel antibiotic resistance determinant in Gram-negative bacteria.

2018-09-23 to 2022-09-29 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: 2124508
Source: Self-asserted source
Khondaker Miraz Rahman via DimensionsWizard

Development of ARB-Linked 4-oxoquinolizine Antibiotics with Extended Spectrum Activity

2017-12 to 2020-12 | Award
Emergent Biosolutions (Maryland, US)
GRANT_NUMBER: JGAWUMR
Source: Self-asserted source
Khondaker Miraz Rahman

Using chemical modification of a novel antimicrobial drug scaffold to reduce efflux from multridrug resistant Gram-negative ESKAPE pathogens

2015-09-30 to 2019-09-29 | Grant
Biotechnology and Biological Sciences Research Council (Swindon, GB)
GRANT_NUMBER: BB/M015033/1
Source: Self-asserted source
Khondaker Miraz Rahman via DimensionsWizard

The Development of Novel Highly-Cytotoxic MGBA (Minor Groove Binding Agent) Payloads for Antibody Drug Conjugates (ADCs).

KCL Confidence in Concept 2013

2014-03-01 to 2016-04-29 | Grant
Medical Research Council (London, GB)
GRANT_NUMBER: MC_PC_13065
Source: Self-asserted source
Khondaker Miraz Rahman via DimensionsWizard

Novel NF-kB Transcription Factor Inhibitors for the Treatment of Haematological Cancers

2012-10-01 to 2016-03-31 | Grant
Worldwide Cancer Research (St Andrews, GB)
GRANT_NUMBER:

WCR-12-1263

Source: Self-asserted source
Khondaker Miraz Rahman via DimensionsWizard

Peer review (132 reviews for 37 publications/grants)

Review activity for ACS infectious diseases. (6)
Review activity for ACS medicinal chemistry letters. (2)
Review activity for Advanced science. (2)
Review activity for Angewandte Chemie. (1)
Review activity for Antimicrobial agents and chemotherapy. (1)
Review activity for Biochemical journal. (2)
Review activity for Biochemical pharmacology. (2)
Review activity for Bioorganic & medicinal chemistry letters. (1)
Review activity for Bioorganic & medicinal chemistry. (4)
Review activity for British journal of pharmacology. (2)
Review activity for Chemical communications. (7)
Review activity for ChemMedChem. (2)
Review activity for Communications biology. (2)
Review activity for Critical reviews in microbiology. (1)
Review activity for Heliyon. (9)
Review activity for Journal of antimicrobial chemotherapy. (2)
Review activity for Journal of biomolecular structure and dynamics. (1)
Review activity for Journal of materials chemistry. (1)
Review activity for Journal of medicinal chemistry. (24)
Review activity for Journal of pharmacy and pharmacology. (2)
Review activity for MedChemComm. (3)
Review activity for Medicine. (1)
Review activity for Microbial drug resistance. (1)
Review activity for Molecules. (3)
Review activity for Natural product reports. (2)
Review activity for Nature communications (2)
Review activity for New journal of chemistry. (4)
Review activity for npj biofilms and microbiomes. (2)
Review activity for Organic & biomolecular chemistry. (18)
Review activity for Pharmaceutics. (2)
Review activity for PloS one. (2)
Review activity for RSC advances (4)
Review activity for RSC medicinal chemistry. (4)
Review activity for Science advances. (2)
Review activity for Scientific reports. (6)
Review activity for Theranostics (1)
Review activity for Tuberculosis. (1)