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Activities

Employment (5)

Prelude Corporation: Laguna Hills, CA, US

2010-07 to 2015-12 | Senior Director, Scientific and Clinical Affairs
Employment
Source: Self-asserted source
Steven Linke

Prediction Sciences: La Jolla, CA, US

2004-08 to 2010-06 | Senior Scientist
Employment
Source: Self-asserted source
Steven Linke

Sanford Burnham Prebys Medical Discovery Institute: La Jolla, CA, US

2002-09 to 2004-03 | Junior Faculty (Research Associate) (Signal Transduction Program)
Employment
Source: Self-asserted source
Steven Linke

National Cancer Institute: Bethesda, MD, US

1997-06 to 2002-05 | Cancer Research Training Award Fellow (Laboratory of Human Carcinogenesis)
Employment
Source: Self-asserted source
Steven Linke

Salk Institute for Biological Studies: La Jolla, CA, US

1996-09 to 1997-04 | Post-doctoral fellow (Gene Expression Laboratory)
Employment
Source: Self-asserted source
Steven Linke

Education and qualifications (3)

University of California San Diego: La Jolla, CA, US

1991-09 to 1996-08 | PhD/Biology (Biology)
Education
Source: Self-asserted source
Steven Linke

North Dakota State University: Fargo, ND, US

1986-09 to 1991-03 | BS/Biotechnology
Education
Source: Self-asserted source
Steven Linke

North Dakota State University: Fargo, ND, US

1986-09 to 1991-03 | BS/Microbiology
Education
Source: Self-asserted source
Steven Linke

Funding (5)

Multi-marker prognostic profile to predict invasive progression in DCIS patients

Source: Self-asserted source
Steven Linke via DimensionsWizard

SBIR Phase II: Multi-Marker Prognostic Test for Breast Cancer Outcome

Source: Self-asserted source
Steven Linke via DimensionsWizard

GeneRx - colorectal cancer recurrence prediction

Source: Self-asserted source
Steven Linke via DimensionsWizard

SBIR Phase I: Multi-Marker Prognostic Test for Breast Cancer Outcome

Source: Self-asserted source
Steven Linke via DimensionsWizard

GeneRx - colorectal cancer recurrence prediction

Source: Self-asserted source
Steven Linke via DimensionsWizard

Works (35)

Prognostic Risk Assessment and Prediction of Radiotherapy Benefit for Women with Ductal Carcinoma In Situ (DCIS) of the Breast, in a Randomized Clinical Trial (SweDCIS)

Cancers
2021-12 | Journal article | Author
Contributors: Fredrik Wärnberg; Per Karlsson; Erik Holmberg; Kerstin Sandelin; Pat W. Whitworth; Jess Savala; Todd Barry; Glen Leesman; Steven Linke; Steve Shivers et al.
Source: check_circle
Multidisciplinary Digital Publishing Institute
grade
Preferred source (of 2)‎

Image analysis algorithms for immunohistochemical assessment of cell death events and fibrosis in tissue sections

Journal of Histochemistry & Cytochemistry
2009 | Journal article
Source: Self-asserted source
Steven Linke

Prognostic marker profile to assess risk in stage I--III hormone receptor-positive breast cancer patients

International journal of cancer
2009 | Journal article
Source: Self-asserted source
Steven Linke

Diagnostic markers predictive of outcomes in colorectal cancer treatment and progression and methods of use thereof

2009-11 | Other
Source: Self-asserted source
Steven Linke

Diagnostic markers of breast cancer treatment and progression and methods of use thereof

2009-03 | Other
Source: Self-asserted source
Steven Linke

A multimarker model to predict outcome in tamoxifen-treated breast cancer patients.

Clinical cancer research
2006 | Journal article
Source: Self-asserted source
Steven Linke

Diagnostic markers of breast cancer treatment and progression and methods of use thereof

2006-12 | Other
Source: Self-asserted source
Steven Linke

BLM helicase facilitates Mus81 endonuclease activity in human cells

Cancer research
2005 | Journal article
Source: Self-asserted source
Steven Linke

Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest

J Cell Biol
2004 | Journal article
Source: Self-asserted source
Steven Linke

The mismatch DNA repair heterodimer, hMSH2/6, regulates BLM helicase

Oncogene
2004 | Journal article
Source: Self-asserted source
Steven Linke

BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination

The EMBO journal
2003 | Journal article
Source: Self-asserted source
Steven Linke

Human malignant glioma cell lines are sensitive to low radiation doses

International journal of cancer
2003 | Journal article
Source: Self-asserted source
Steven Linke

Involvement of Crm1 in hepatitis B virus X protein-induced aberrant centriole replication and abnormal mitotic spindles

Molecular and cellular biology
2003 | Journal article
Source: Self-asserted source
Steven Linke

Nitric oxide-induced cellular stress and p53 activation in chronic inflammation

Proceedings of the national academy of sciences
2003 | Journal article
Source: Self-asserted source
Steven Linke

p53 interacts with hRAD51 and hRAD54, and directly modulates homologous recombination

Cancer research
2003 | Journal article
Source: Self-asserted source
Steven Linke

UV-C-induced DNA damage leads to p53-dependent nuclear trafficking of PML

Oncogene
2003 | Journal article
Source: Self-asserted source
Steven Linke

The p53 network in lung carcinogenesis

Oncogene
2002 | Journal article
Source: Self-asserted source
Steven Linke

The processing of Holliday junctions by BLM and WRN helicases is regulated by p53

Journal of Biological Chemistry
2002 | Journal article
Source: Self-asserted source
Steven Linke

The p53 network in lung carcinogenesis

Oncogene
2002-10 | Journal article
Part of ISSN: 0950-9232
Contributors: Ana I Robles; Steven P Linke; Curtis C Harris
Source: Self-asserted source
Steven Linke via Crossref Metadata Search

DNA damage-inducible gene p33ING2 negatively regulates cell proliferation through acetylation of p53

Proceedings of the National Academy of Sciences
2001 | Journal article
Source: Self-asserted source
Steven Linke

Functional interaction of p53 and BLM DNA helicase in apoptosis

Journal of Biological Chemistry
2001 | Journal article
Source: Self-asserted source
Steven Linke

Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis

Nature genetics
2001 | Journal article
Source: Self-asserted source
Steven Linke

Identification of a functional domain in a GADD45-mediated G2/M checkpoint

Journal of Biological Chemistry
2000 | Journal article
Source: Self-asserted source
Steven Linke

p53-mediated apoptosis and genomic instability syndromes

Breast Cancer Research
2000-03 | Journal article
Part of ISSN: 1465-542X
Contributors: EA Spillare; XW Wang; SP Linke; A Robles; CC Harris
Source: Self-asserted source
Steven Linke via Crossref Metadata Search

Centrosome amplification and a defective G2--M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform--deficient cells

Molecular cell
1999 | Journal article
Source: Self-asserted source
Steven Linke

Has the smart bomb been defused?

Nature
1998-09 | Journal article
Part of ISSN: 0028-0836
Contributors: Steven P. Linke
Source: Self-asserted source
Steven Linke via Crossref Metadata Search

Cell Cycle Control of Genetic Stability

Genomic Instability and Immortality in Cancer
1997 | Other
Part of ISBN: 9781461374480
Contributors: Geoffrey M. Wahl; Steven P. Linke; Thomas G. Paulson; Li-chun Huang
Source: Self-asserted source
Steven Linke via Crossref Metadata Search

DNA rereplication in the presence of mitotic spindle inhibitors in human and mouse fibroblasts lacking either p53 or pRb function

Cancer research
1997 | Journal article
Source: Self-asserted source
Steven Linke

p53 mediates permanent arrest over multiple cell cycles in response to $γ$-irradiation

Cancer research
1997 | Journal article
Source: Self-asserted source
Steven Linke

p53-mediated accumulation of hypophosphorylated pRb after the G 1 restriction point fails to halt cell cycle progression

Oncogene
1997 | Journal article
Source: Self-asserted source
Steven Linke

A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.

Genes & development
1996 | Journal article
Source: Self-asserted source
Steven Linke

The tumorigenic potential and cell growth characteristics of p53-deficient cells are equivalent in the presence or absence of Mdm2

Proceedings of the National Academy of Sciences
1996 | Journal article
Source: Self-asserted source
Steven Linke

Genetic instability as a consequence of inappropriate entry into and progression through S-phase

Cancer and Metastasis Reviews
1995 | Journal article
Source: Self-asserted source
Steven Linke

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts.

Genes & development
1994 | Journal article
Source: Self-asserted source
Steven Linke

Protein-kinase-A-dependent activator in transcription factor CREB reveals new role for CREM repressers

Nature
1993 | Journal article
Source: Self-asserted source
Steven Linke